Will finasteride kill your beard growth?

Haircafe
24 Jul 202008:41

Summary

TLDR视频讨论了抑制二氢睾酮(DHT)是否会影响胡须生长,以及非那雄胺(一种抑制DHT的药物)是否对胡须生长有害。视频中提到,面部毛发与头皮毛发在对雄激素的反应上有所不同,面部毛发更接近身体毛发,拥有更多的雄激素受体和5α-还原酶活性。尽管DHT会破坏头皮毛发,但对面部毛发的生长却是有益的,这种现象被称为“雄激素悖论”。研究显示,即使在DHT水平较低的情况下,胡须密度也可能增加,表明睾酮对胡须密度的影响更大。医生论坛上的讨论表明,使用非那雄胺的患者并未出现面部毛发生长问题。因此,非那雄胺不太可能对胡须生长产生负面影响,即使有,也只可能是生长速度减慢,而不会影响胡须密度。

Takeaways

  • 🧔 视频作者本人无法长出浓密的胡须,这与遗传有关,并非与雄激素水平直接相关。
  • 💊 Finasteride(非那雄胺)是一种药物,用于抑制DHT(二氢睾酮)的生成,以治疗脱发。
  • 🤔 人们担心Finasteride可能因为抑制DHT而影响胡须的生长,但视频作者提出需要科学依据来验证这一点。
  • 🧬 面部毛发与头皮毛发虽然看起来相似,但在对雄激素的反应上存在很大差异。
  • 🔬 研究表明,面部毛发的毛囊比头皮毛发的毛囊有更多的雄激素受体和5α-还原酶活性。
  • 😯 医学界称之为“雄激素悖论”,即雄激素对面部毛发生长是有益的,但对头皮毛发则是有害的。
  • 🧪 一项研究比较了胡须毛囊和头皮毛囊的5α-还原酶活性,发现胡须毛囊产生的DHT显著多于头皮毛囊。
  • 📊 另一项研究观察了胡须和头皮的真皮乳头细胞,发现胡须细胞对雄激素更为敏感。
  • 🌾 研究还发现,患有乳糜泻(celiac disease)的人由于DHT水平较低,胡须密度增加,但线性生长减少。
  • 👨‍⚕️ 医生论坛上的皮肤科医生表示,他们没有观察到Finasteride使用对胡须生长有负面影响的案例。
  • 💪 视频作者总结说,Finasteride不会损害胡须生长,即使有影响,可能也只是减缓生长速度,而不会影响密度。

Q & A

  • 抑制DHT(dehydrotestosterone)会影响胡须生长吗?

    -根据视频内容,抑制DHT通常不会对胡须生长产生负面影响。面部毛发(包括胡须)与身体毛发和阴毛在对雄激素的反应上更为相似,而与头皮毛发不同。面部毛发对雄激素(特别是DHT)更为敏感,并且雄激素对胡须生长是有益的,这被称为雄激素悖论。

  • Finasteride(非那雄胺)会损害胡须生长吗?

    -视频指出,尽管Finasteride抑制DHT,但并没有确凿的证据表明它会损害胡须生长。医生论坛中的皮肤科医生表示,他们的患者使用Finasteride后在胡须生长方面没有出现负面情况。

  • 面部毛发与头皮毛发在对雄激素的反应上有何不同?

    -面部毛发,包括胡须,与身体毛发和阴毛相比,有更多的雄激素受体和5α-还原酶活性。尽管如此,雄激素对面部毛发是有益的,而对那些遗传上有脱发倾向的人来说,雄激素对头皮毛发的影响是有害的。

  • 雄激素悖论是什么?

    -雄激素悖论是指雄激素,尤其是DHT,对面部毛发生长有益,而对头皮毛发生长有害的现象。尽管面部毛发和身体毛发有更多的雄激素受体和5α-还原酶活性,但它们对雄激素的反应与头皮毛发不同。

  • 为什么Finasteride会增加睾酮水平?

    -Finasteride通过抑制5α-还原酶活性来降低DHT水平,这导致睾酮水平相对增加,大约增加15%。这种增加的睾酮可能有助于胡须密度的增加。

  • 关于DHT和睾酮对胡须生长的影响,有哪些科学研究?

    -视频中提到了两项科学研究:一项研究比较了胡须毛囊和头皮毛囊的5α-还原酶活性和培养的真皮乳头细胞,发现胡须毛囊有更高水平的DHT。另一项研究观察了胡须和头皮的真皮乳头细胞培养,发现胡须细胞有更多的雄激素受体。

  • 麸质不耐症(celiac disease)如何影响DHT和睾酮水平?

    -麸质不耐症患者往往有较低的DHT水平和较高的睾酮水平。一项研究观察了这些人的线性头发生长和胡须密度,发现与健康个体相比,麸质不耐症患者的线性头发生长减少,而胡须密度增加。

  • 为什么视频作者认为Finasteride不会影响胡须生长?

    -视频作者认为,尽管Finasteride降低了DHT水平,但胡须毛囊的5α-还原酶活性更高,且有更多的雄激素受体,这可能弥补了DHT的减少。此外,使用Finasteride导致的睾酮水平增加可能有助于胡须密度的增加。

  • 视频作者对秃顶和胡须的关联有何看法?

    -视频作者认为,秃顶男性留胡须并不一定意味着他们更擅长生长胡须,而可能是因为他们在补偿头皮毛发的缺失。作者认为秃顶和胡须的组合看起来非常俗气和普通。

  • 视频作者对于年轻人使用Finasteride有何建议?

    -视频作者建议,对Finasteride感兴趣的年轻人应该像其他人一样与医生交谈,以确保他们在开始使用Finasteride之前已经完成了身体发育。但他们不应该担心Finasteride会影响他们的面部毛发生长。

Outlines

00:00

🧔 抑制DHT对胡须生长的影响

视频讨论了抑制DHT(二氢睾酮)是否会对胡须生长产生负面影响,以及使用抑制DHT的药物Finasteride是否对胡须生长有害。视频作者自嘲自己胡须稀疏,即使使用Finasteride也不太可能影响其胡须生长。作者提到胡须生长与遗传因素有关,并非完全依赖于雄激素水平。视频进一步探讨了雄激素对胡须生长的作用,指出胡须与身体其他部位的毛发在对雄激素的反应上更为相似,而与头皮毛发不同。提到了所谓的'雄激素悖论',即雄激素对胡须生长是有益的,而对头皮毛发则是有害的。此外,还介绍了两项科学研究,一项比较了胡须和头皮毛囊的5α还原酶活性,另一项研究了胡须和头皮的真皮乳头细胞对雄激素的敏感性。

05:02

💊 Finasteride对胡须生长的实际影响

视频作者继续讨论了Finasteride对胡须生长的具体影响。尽管没有直接关于Finasteride对胡须生长影响的研究,但通过医生论坛上的讨论,皮肤科医生们并没有观察到他们的患者在使用Finasteride后胡须生长出现问题。作者推测,由于胡须毛囊具有更高的5α还原酶活性和更多的雄激素受体,即使Finasteride降低了DHT水平,胡须生长可能也不会受到负面影响。此外,Finasteride使用后体内睾酮水平的增加可能有助于胡须密度的增加。视频作者还提到了一项研究,该研究观察了患有乳糜泻(一种自身免疫性疾病,患者不能摄入麸质)的男性,发现他们虽然DHT水平较低,但胡须密度较高,这进一步支持了DHT对胡须生长长度的影响较小,而睾酮对胡须密度的影响较大。最后,作者总结说,人们不需要在头皮毛发和胡须毛发之间做出选择,Finasteride不会损害胡须的生长,对于担心Finasteride影响胡须生长的人,他们可能即使不使用Finasteride也会有稀疏的胡须。

Mindmap

Keywords

💡dht

DHT,即二氢睾酮,是一种雄激素,与男性特征的发展有关。在视频中,DHT被讨论为可能影响胡须生长的因素之一。例如,视频提到抑制DHT是否会对胡须生长产生不利影响,以及Finasteride(一种药物)如何通过抑制DHT来影响胡须生长。

💡finasteride

Finasteride是一种常用于治疗男性脱发的药物,它通过抑制DHT的产生来工作。视频主要探讨了Finasteride是否会影响胡须的生长,以及它是否对那些想要长胡须的人有害。

💡胡须生长

胡须生长是视频中讨论的主要主题之一。视频解释了胡须生长与DHT和睾酮之间的关系,并探讨了Finasteride对胡须生长可能的影响。例如,视频提到即使使用Finasteride,胡须的生长速度可能会减慢,但密度可能不会减少。

💡androgens

雄激素是一类性激素,包括睾酮和DHT。在视频中,雄激素被讨论为影响胡须和头皮头发生长的关键因素。视频指出,尽管雄激素对头皮头发有破坏作用,但对胡须生长却是有益的。

💡5a reductase

5a还原酶是一种酶,它将睾酮转化为DHT。视频中提到,胡须毛囊中的5a还原酶活性比头皮毛囊中的要高,这表明胡须毛囊对雄激素更为敏感。

💡androgen paradox

雄激素悖论是医学界用来描述雄激素对不同类型头发生长影响不同的现象。视频解释说,尽管雄激素(特别是DHT)对头皮头发有破坏作用,但对胡须生长却是有益的。

💡celiac disease

乳糜泻是一种自身免疫性疾病,患者对麸质过敏。视频中提到,乳糜泻患者通常具有较低的DHT水平和较高的睾酮水平,这为研究DHT和睾酮对胡须生长的影响提供了一个有趣的案例。

💡linear hair growth

线性头发生长指的是头发随时间增长的长度。视频中提到,乳糜泻患者的线性头发生长速度较慢,这与他们较低的DHT水平有关。

💡beard density

胡须密度指的是胡须的密集程度。视频指出,乳糜泻患者的胡须密度较高,这可能与他们较高的睾酮水平有关。

💡testosterone

睾酮是主要的男性性激素,对肌肉生长、性特征发展等有重要作用。视频中讨论了睾酮对胡须生长的影响,指出睾酮可能对胡须密度有积极作用,而DHT对线性头发生长更为重要。

Highlights

抑制DHT(脱氢睾酮)是否会对胡须生长产生负面影响是视频中常被问及的问题之一。

Finasteride(非那雄胺)抑制DHT,但对胡须生长的影响尚不明确。

讲述者自身胡须生长情况不佳,与Finasteride使用无关。

胡须生长与遗传有关,并非完全依赖雄激素。

面部毛发与身体毛发在对雄激素反应上更为相似,与头皮毛发不同。

雄激素(特别是DHT)对胡须生长有益,这被称为雄激素悖论。

人类生理学和激素对人类毛发作用的某些方面没有完美的解释。

两项基础科学研究探讨了DHT对胡须毛发与头皮毛发的影响。

研究发现胡须毛囊比头皮毛囊有更高水平的DHT。

胡须毛发的毛囊细胞对雄激素更为敏感。

研究涉及12名健康男性和8名患有乳糜泻的男性,探讨了DHT和睾酮对胡须生长的影响。

乳糜泻患者相比健康人群,胡须密度增加,线性生长减少。

DHT对线性胡须生长很重要,而睾酮对胡须密度更重要。

目前没有关于Finasteride对胡须生长影响的研究,但医生论坛上的皮肤科医生表示没有患者报告负面效果。

Finasteride可能会减少线性胡须生长,但可能通过增加睾酮来增加胡须密度。

使用Finasteride的人不必担心它会影响胡须生长。

青少年在考虑使用Finasteride时应咨询医生,确保身体发育完成。

面部毛发对DHT非常敏感,可能不会受到Finasteride影响。

人们不必在头皮毛发和面部毛发之间做出选择,Finasteride不会破坏胡须生长。

讲述者个人不喜欢秃顶和胡须的组合,认为这是一种陈词滥调的外观。

Transcripts

play00:01

what is up homies so one of the

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questions i get asked about the most of

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my videos is whether or not suppressing

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dht

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dehydrotestosterone can adversely affect

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the development of beard growth

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and if so does that mean finasteride

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which obviously suppresses dht is

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harmful to beer development

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well for obvious reasons i'm not going

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to pretend i know anything about growing

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a good beard

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what you're looking at is my facial hair

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after six days not shaving and it's

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possible from your perspective i still

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look like i am clean shaven

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that's right i only have to shave about

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once a week or so and if i stop

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shaving for about six months maybe i'll

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start to have a beard on par with your

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average 15 year old boy

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this has nothing to do with my

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finasteride use i have never been able

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to grow good facial hair

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in high school when my friends bragged

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about how their beards were growing in

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i would just lie and say that i do have

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facial hair but i just prefer to just

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shave it bro

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and even my senior year of college my

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face was as smooth as a baby's ass and

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it wasn't until i was about 24 years old

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or so that i noticed some little spuds

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on my face that at best can be

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interpreted as sorry excuses for facial

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hair

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and as it turns out this is just a

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genetic trait and not necessarily linked

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to androgens

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some people even if they have high

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androgen levels will just not be able to

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grow good beards

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and i obviously count amongst that

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population and so

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i over the years have just accepted as

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part of my identity now

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i know not every man is going to be okay

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with poverty facial hair like me

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facial hair can be used to accentuate an

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already handsome face

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or it can be even used to help hide some

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less flattering facial features

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such as acne scars or just poor facial

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structure and a weak jawline for

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instance

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and they're also men who want to grow a

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beard for cultural or spiritual reasons

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so there are clearly many reasons as to

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why growing a beard is important for a

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lot of men

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so because of that many men are

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reluctant to start finasteride out of

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fear

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that its role in suppressing dht will

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wreak havoc on their facial hair

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so to better understand this let's look

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at some of the science we have regarding

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androgens

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and the role they play in beer

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development and growth so

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the first thing to make note of is that

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your facial hair and scalp hair

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even though they look similar and have a

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similar texture are

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quite a bit different your facial hair

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has a lot more in common with your body

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hair and even your pubic hair

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in regards to how it responds to

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androgens in fact it's common knowledge

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that androgens namely dht are what

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destroy scalp hair

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and that is why finasteride works since

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it lowers dht levels on the scalp

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however

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facial hair and body hair have more

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engine receptors as well as more 5a

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reductase activity

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compared to scalp hair yet despite this

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it seems androgens are

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actually beneficial to facial hair this

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is what is known in the medical

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community as the androgen paradox now

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next time someone tries to bring up

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intelligent design ask them what kind of

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would think it was a good idea

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idea to design men so that hormones grow

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hair all over the body

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the face the armpits the ass but for

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some reason makes us go bald in the

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scalp

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i mean this should make it clear that

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human evolution is not perfect

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and oftentimes there is no good

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explanation for certain aspects

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of human physiology and the role

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hormones play on human hair

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is certainly a prime example of this so

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there are two basic science studies

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which i'll link below that examine dht

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and facial hair versus scalp hair in the

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first study the investigators compared

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5a reductase activity and cultured

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dermal papilla cells

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from beard follicles and scalp follicles

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they found that testosterone was taken

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up by both kinds of hair follicles

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but beard follicles were found to have

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significantly higher levels of dht

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whereas scalp hair follicles didn't this

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implies that the testosterone in

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facial hair is more actively metabolized

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to dht

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than in scalp hair implying that there

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is more 5a reductase activity in beard

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than in scalp follicles

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the other study looked at cultures of

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dermal papilla cells in the beard

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and in the scalp and they found that

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beard papilla cells had

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many more anger receptors than scalp

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cells this implies that facial

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hair papilla cells are more sensitive to

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androgens than scalp hair

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however it seems that the effect of

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androgens on facial hair is beneficial

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whereas in those genetically predisposed

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to hair loss the effect of androgens on

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the scalp

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is deleterious so to further explore

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this androgen paradox

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let us look at a study which involved 12

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healthy men as well as

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eight men who had celiac disease now for

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those who don't know what celiac disease

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is

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it means you can't eat gluten and i'm

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not talking about impressionable

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bone broth and butter coffee slurping

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karen's who just

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imagined they can't eat gluten after

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reading the first two pages of wheat

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belly

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when they were shopping for coconut oil

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and homeopathic remedies at whole foods

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one day

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i'm talking about people who will get

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severe inflammatory bowel issues

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if they even consume a small amount of

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it what is especially interesting about

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people with celiac disease and this is

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something i had no idea of

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is that it turns out they tend to have

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lower dht and higher testosterone

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compared to healthy individuals now i'll

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like a study below on this phenomenon

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but getting back to the present study

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they looked at both linear hair growth

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and beer density in the groups of people

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with normal and

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abnormal testosterone and dht levels

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linear hair growth is basically how much

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the hair grows over time

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very interestingly interestingly they

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found that linear hair growth was

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reduced in the celiac patients compared

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to the controls

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whereas beard density was increased in

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the celiac patients compared to controls

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now remember the celiac patients have

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lower dht levels and higher testosterone

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levels implying that

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dht is important for linear hair growth

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but testosterone is more important for

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beard density

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now this is a small study but it is the

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best data we have so far on different

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effects of dht and testosterone on beard

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growth

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so i would count it as valuable so what

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about

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finasteride specifically well there is

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no study on finasteride's role on facial

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hair development that i can find

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but searching a doctor's forum that

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included dermatologist

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point of view it seems that none of them

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had any experience with their patients

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experiencing anything negative regarding

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finasteride use and beard growth

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if there is any problem then it must be

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very rare or else there probably would

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be more data about it online so

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what can we make out of all this well we

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know that finasteride decreases dht

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but we also know that 5a reductase

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activity is higher

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on the hair follicle of the beard

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compared to the scalp hair and that

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there are more angioreceptors on the

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facial hair receptors compared to the

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scalp

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so it's possible the reason facial hair

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doesn't seem to be adversely affected

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is because the extra 5a reductase

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activity

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and higher quantity of angine receptors

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makes up for the decrease in dht

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also it could be theoretically helped by

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the increase in testosterone from using

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finasteride

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which causes about a 15 percent increase

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in testosterone

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it might be that the increase in

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testosterone increases beard density as

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the study indicated but the only change

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would be that linear hair growth would

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be reduced

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so you wouldn't have to shave as often

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and it also may take longer to grow a

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beard as a result of the reduction in

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dht

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so anyone looking for an excuse to not

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use finasteride

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well now you have one fewer excuse

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finasteride will not hurt your beard

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gains and anyone who has poor facial

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hair while on finasteride

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likely would have still had poor facial

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hair even if they didn't use finasteride

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kind of like me

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so adolescents who are interested in

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finasteride should of course talk to

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their doctor just like anyone else

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in order to make sure they're finished

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with physical maturation before starting

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finasteride

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but they shouldn't worry about

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finasteride affecting their facial hair

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development i mean perhaps it will mean

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their beard will

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grow a little bit more slowly but

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testosterone as we've already

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established is the hormone

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that is responsible for facial hair

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development and density not so much so

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dht and even still

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facial hair is so sensitive to dht uh

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due to the high quantity of android

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receptors as well as the presence of 5a

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reductase

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that it may not even matter either way

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even if you are on finasteride so

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i've also seen some reddit posts where

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people say their facial hair slows but

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it hasn't decreased in density at all

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which is anecdotal of course but

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nevertheless corresponds to the research

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done

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on the subject so in conclusion people

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do not have to choose between their

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scalp hair and their facial hair

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i mean i think a lot of people associate

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beard hair with dh

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dht just because a lot of bald guys grow

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beards but they're just doing that

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because they are compensating not

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because they're better at growing beards

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necessarily

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and if you ask me the bald and bearded

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look is just really cliched and boring

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looking i mean it's such a

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dime a dozen look i mean they basically

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look like they're just trying to grow

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their hair upside down so i can't stand

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that look so

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no finasteride won't screw up your beard

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gains so stop worrying about it

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and with that i am out and i'll be back

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with more content

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soon but keep in mind i'm still doing

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some hardcore gaming tonight i'm

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fighting soft some mongolian invaders

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and goes to tsujima

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uh so don't expect me to be too active

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tonight but i will be back soon

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and see you next time

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