Will finasteride kill your beard growth?
Summary
TLDR视频讨论了抑制二氢睾酮(DHT)是否会影响胡须生长,以及非那雄胺(一种抑制DHT的药物)是否对胡须生长有害。视频中提到,面部毛发与头皮毛发在对雄激素的反应上有所不同,面部毛发更接近身体毛发,拥有更多的雄激素受体和5α-还原酶活性。尽管DHT会破坏头皮毛发,但对面部毛发的生长却是有益的,这种现象被称为“雄激素悖论”。研究显示,即使在DHT水平较低的情况下,胡须密度也可能增加,表明睾酮对胡须密度的影响更大。医生论坛上的讨论表明,使用非那雄胺的患者并未出现面部毛发生长问题。因此,非那雄胺不太可能对胡须生长产生负面影响,即使有,也只可能是生长速度减慢,而不会影响胡须密度。
Takeaways
- 🧔 视频作者本人无法长出浓密的胡须,这与遗传有关,并非与雄激素水平直接相关。
- 💊 Finasteride(非那雄胺)是一种药物,用于抑制DHT(二氢睾酮)的生成,以治疗脱发。
- 🤔 人们担心Finasteride可能因为抑制DHT而影响胡须的生长,但视频作者提出需要科学依据来验证这一点。
- 🧬 面部毛发与头皮毛发虽然看起来相似,但在对雄激素的反应上存在很大差异。
- 🔬 研究表明,面部毛发的毛囊比头皮毛发的毛囊有更多的雄激素受体和5α-还原酶活性。
- 😯 医学界称之为“雄激素悖论”,即雄激素对面部毛发生长是有益的,但对头皮毛发则是有害的。
- 🧪 一项研究比较了胡须毛囊和头皮毛囊的5α-还原酶活性,发现胡须毛囊产生的DHT显著多于头皮毛囊。
- 📊 另一项研究观察了胡须和头皮的真皮乳头细胞,发现胡须细胞对雄激素更为敏感。
- 🌾 研究还发现,患有乳糜泻(celiac disease)的人由于DHT水平较低,胡须密度增加,但线性生长减少。
- 👨⚕️ 医生论坛上的皮肤科医生表示,他们没有观察到Finasteride使用对胡须生长有负面影响的案例。
- 💪 视频作者总结说,Finasteride不会损害胡须生长,即使有影响,可能也只是减缓生长速度,而不会影响密度。
Q & A
抑制DHT(dehydrotestosterone)会影响胡须生长吗?
-根据视频内容,抑制DHT通常不会对胡须生长产生负面影响。面部毛发(包括胡须)与身体毛发和阴毛在对雄激素的反应上更为相似,而与头皮毛发不同。面部毛发对雄激素(特别是DHT)更为敏感,并且雄激素对胡须生长是有益的,这被称为雄激素悖论。
Finasteride(非那雄胺)会损害胡须生长吗?
-视频指出,尽管Finasteride抑制DHT,但并没有确凿的证据表明它会损害胡须生长。医生论坛中的皮肤科医生表示,他们的患者使用Finasteride后在胡须生长方面没有出现负面情况。
面部毛发与头皮毛发在对雄激素的反应上有何不同?
-面部毛发,包括胡须,与身体毛发和阴毛相比,有更多的雄激素受体和5α-还原酶活性。尽管如此,雄激素对面部毛发是有益的,而对那些遗传上有脱发倾向的人来说,雄激素对头皮毛发的影响是有害的。
雄激素悖论是什么?
-雄激素悖论是指雄激素,尤其是DHT,对面部毛发生长有益,而对头皮毛发生长有害的现象。尽管面部毛发和身体毛发有更多的雄激素受体和5α-还原酶活性,但它们对雄激素的反应与头皮毛发不同。
为什么Finasteride会增加睾酮水平?
-Finasteride通过抑制5α-还原酶活性来降低DHT水平,这导致睾酮水平相对增加,大约增加15%。这种增加的睾酮可能有助于胡须密度的增加。
关于DHT和睾酮对胡须生长的影响,有哪些科学研究?
-视频中提到了两项科学研究:一项研究比较了胡须毛囊和头皮毛囊的5α-还原酶活性和培养的真皮乳头细胞,发现胡须毛囊有更高水平的DHT。另一项研究观察了胡须和头皮的真皮乳头细胞培养,发现胡须细胞有更多的雄激素受体。
麸质不耐症(celiac disease)如何影响DHT和睾酮水平?
-麸质不耐症患者往往有较低的DHT水平和较高的睾酮水平。一项研究观察了这些人的线性头发生长和胡须密度,发现与健康个体相比,麸质不耐症患者的线性头发生长减少,而胡须密度增加。
为什么视频作者认为Finasteride不会影响胡须生长?
-视频作者认为,尽管Finasteride降低了DHT水平,但胡须毛囊的5α-还原酶活性更高,且有更多的雄激素受体,这可能弥补了DHT的减少。此外,使用Finasteride导致的睾酮水平增加可能有助于胡须密度的增加。
视频作者对秃顶和胡须的关联有何看法?
-视频作者认为,秃顶男性留胡须并不一定意味着他们更擅长生长胡须,而可能是因为他们在补偿头皮毛发的缺失。作者认为秃顶和胡须的组合看起来非常俗气和普通。
视频作者对于年轻人使用Finasteride有何建议?
-视频作者建议,对Finasteride感兴趣的年轻人应该像其他人一样与医生交谈,以确保他们在开始使用Finasteride之前已经完成了身体发育。但他们不应该担心Finasteride会影响他们的面部毛发生长。
Outlines
🧔 抑制DHT对胡须生长的影响
视频讨论了抑制DHT(二氢睾酮)是否会对胡须生长产生负面影响,以及使用抑制DHT的药物Finasteride是否对胡须生长有害。视频作者自嘲自己胡须稀疏,即使使用Finasteride也不太可能影响其胡须生长。作者提到胡须生长与遗传因素有关,并非完全依赖于雄激素水平。视频进一步探讨了雄激素对胡须生长的作用,指出胡须与身体其他部位的毛发在对雄激素的反应上更为相似,而与头皮毛发不同。提到了所谓的'雄激素悖论',即雄激素对胡须生长是有益的,而对头皮毛发则是有害的。此外,还介绍了两项科学研究,一项比较了胡须和头皮毛囊的5α还原酶活性,另一项研究了胡须和头皮的真皮乳头细胞对雄激素的敏感性。
💊 Finasteride对胡须生长的实际影响
视频作者继续讨论了Finasteride对胡须生长的具体影响。尽管没有直接关于Finasteride对胡须生长影响的研究,但通过医生论坛上的讨论,皮肤科医生们并没有观察到他们的患者在使用Finasteride后胡须生长出现问题。作者推测,由于胡须毛囊具有更高的5α还原酶活性和更多的雄激素受体,即使Finasteride降低了DHT水平,胡须生长可能也不会受到负面影响。此外,Finasteride使用后体内睾酮水平的增加可能有助于胡须密度的增加。视频作者还提到了一项研究,该研究观察了患有乳糜泻(一种自身免疫性疾病,患者不能摄入麸质)的男性,发现他们虽然DHT水平较低,但胡须密度较高,这进一步支持了DHT对胡须生长长度的影响较小,而睾酮对胡须密度的影响较大。最后,作者总结说,人们不需要在头皮毛发和胡须毛发之间做出选择,Finasteride不会损害胡须的生长,对于担心Finasteride影响胡须生长的人,他们可能即使不使用Finasteride也会有稀疏的胡须。
Mindmap
Keywords
💡dht
💡finasteride
💡胡须生长
💡androgens
💡5a reductase
💡androgen paradox
💡celiac disease
💡linear hair growth
💡beard density
💡testosterone
Highlights
抑制DHT(脱氢睾酮)是否会对胡须生长产生负面影响是视频中常被问及的问题之一。
Finasteride(非那雄胺)抑制DHT,但对胡须生长的影响尚不明确。
讲述者自身胡须生长情况不佳,与Finasteride使用无关。
胡须生长与遗传有关,并非完全依赖雄激素。
面部毛发与身体毛发在对雄激素反应上更为相似,与头皮毛发不同。
雄激素(特别是DHT)对胡须生长有益,这被称为雄激素悖论。
人类生理学和激素对人类毛发作用的某些方面没有完美的解释。
两项基础科学研究探讨了DHT对胡须毛发与头皮毛发的影响。
研究发现胡须毛囊比头皮毛囊有更高水平的DHT。
胡须毛发的毛囊细胞对雄激素更为敏感。
研究涉及12名健康男性和8名患有乳糜泻的男性,探讨了DHT和睾酮对胡须生长的影响。
乳糜泻患者相比健康人群,胡须密度增加,线性生长减少。
DHT对线性胡须生长很重要,而睾酮对胡须密度更重要。
目前没有关于Finasteride对胡须生长影响的研究,但医生论坛上的皮肤科医生表示没有患者报告负面效果。
Finasteride可能会减少线性胡须生长,但可能通过增加睾酮来增加胡须密度。
使用Finasteride的人不必担心它会影响胡须生长。
青少年在考虑使用Finasteride时应咨询医生,确保身体发育完成。
面部毛发对DHT非常敏感,可能不会受到Finasteride影响。
人们不必在头皮毛发和面部毛发之间做出选择,Finasteride不会破坏胡须生长。
讲述者个人不喜欢秃顶和胡须的组合,认为这是一种陈词滥调的外观。
Transcripts
what is up homies so one of the
questions i get asked about the most of
my videos is whether or not suppressing
dht
dehydrotestosterone can adversely affect
the development of beard growth
and if so does that mean finasteride
which obviously suppresses dht is
harmful to beer development
well for obvious reasons i'm not going
to pretend i know anything about growing
a good beard
what you're looking at is my facial hair
after six days not shaving and it's
possible from your perspective i still
look like i am clean shaven
that's right i only have to shave about
once a week or so and if i stop
shaving for about six months maybe i'll
start to have a beard on par with your
average 15 year old boy
this has nothing to do with my
finasteride use i have never been able
to grow good facial hair
in high school when my friends bragged
about how their beards were growing in
i would just lie and say that i do have
facial hair but i just prefer to just
shave it bro
and even my senior year of college my
face was as smooth as a baby's ass and
it wasn't until i was about 24 years old
or so that i noticed some little spuds
on my face that at best can be
interpreted as sorry excuses for facial
hair
and as it turns out this is just a
genetic trait and not necessarily linked
to androgens
some people even if they have high
androgen levels will just not be able to
grow good beards
and i obviously count amongst that
population and so
i over the years have just accepted as
part of my identity now
i know not every man is going to be okay
with poverty facial hair like me
facial hair can be used to accentuate an
already handsome face
or it can be even used to help hide some
less flattering facial features
such as acne scars or just poor facial
structure and a weak jawline for
instance
and they're also men who want to grow a
beard for cultural or spiritual reasons
so there are clearly many reasons as to
why growing a beard is important for a
lot of men
so because of that many men are
reluctant to start finasteride out of
fear
that its role in suppressing dht will
wreak havoc on their facial hair
so to better understand this let's look
at some of the science we have regarding
androgens
and the role they play in beer
development and growth so
the first thing to make note of is that
your facial hair and scalp hair
even though they look similar and have a
similar texture are
quite a bit different your facial hair
has a lot more in common with your body
hair and even your pubic hair
in regards to how it responds to
androgens in fact it's common knowledge
that androgens namely dht are what
destroy scalp hair
and that is why finasteride works since
it lowers dht levels on the scalp
however
facial hair and body hair have more
engine receptors as well as more 5a
reductase activity
compared to scalp hair yet despite this
it seems androgens are
actually beneficial to facial hair this
is what is known in the medical
community as the androgen paradox now
next time someone tries to bring up
intelligent design ask them what kind of
would think it was a good idea
idea to design men so that hormones grow
hair all over the body
the face the armpits the ass but for
some reason makes us go bald in the
scalp
i mean this should make it clear that
human evolution is not perfect
and oftentimes there is no good
explanation for certain aspects
of human physiology and the role
hormones play on human hair
is certainly a prime example of this so
there are two basic science studies
which i'll link below that examine dht
and facial hair versus scalp hair in the
first study the investigators compared
5a reductase activity and cultured
dermal papilla cells
from beard follicles and scalp follicles
they found that testosterone was taken
up by both kinds of hair follicles
but beard follicles were found to have
significantly higher levels of dht
whereas scalp hair follicles didn't this
implies that the testosterone in
facial hair is more actively metabolized
to dht
than in scalp hair implying that there
is more 5a reductase activity in beard
than in scalp follicles
the other study looked at cultures of
dermal papilla cells in the beard
and in the scalp and they found that
beard papilla cells had
many more anger receptors than scalp
cells this implies that facial
hair papilla cells are more sensitive to
androgens than scalp hair
however it seems that the effect of
androgens on facial hair is beneficial
whereas in those genetically predisposed
to hair loss the effect of androgens on
the scalp
is deleterious so to further explore
this androgen paradox
let us look at a study which involved 12
healthy men as well as
eight men who had celiac disease now for
those who don't know what celiac disease
is
it means you can't eat gluten and i'm
not talking about impressionable
bone broth and butter coffee slurping
karen's who just
imagined they can't eat gluten after
reading the first two pages of wheat
belly
when they were shopping for coconut oil
and homeopathic remedies at whole foods
one day
i'm talking about people who will get
severe inflammatory bowel issues
if they even consume a small amount of
it what is especially interesting about
people with celiac disease and this is
something i had no idea of
is that it turns out they tend to have
lower dht and higher testosterone
compared to healthy individuals now i'll
like a study below on this phenomenon
but getting back to the present study
they looked at both linear hair growth
and beer density in the groups of people
with normal and
abnormal testosterone and dht levels
linear hair growth is basically how much
the hair grows over time
very interestingly interestingly they
found that linear hair growth was
reduced in the celiac patients compared
to the controls
whereas beard density was increased in
the celiac patients compared to controls
now remember the celiac patients have
lower dht levels and higher testosterone
levels implying that
dht is important for linear hair growth
but testosterone is more important for
beard density
now this is a small study but it is the
best data we have so far on different
effects of dht and testosterone on beard
growth
so i would count it as valuable so what
about
finasteride specifically well there is
no study on finasteride's role on facial
hair development that i can find
but searching a doctor's forum that
included dermatologist
point of view it seems that none of them
had any experience with their patients
experiencing anything negative regarding
finasteride use and beard growth
if there is any problem then it must be
very rare or else there probably would
be more data about it online so
what can we make out of all this well we
know that finasteride decreases dht
but we also know that 5a reductase
activity is higher
on the hair follicle of the beard
compared to the scalp hair and that
there are more angioreceptors on the
facial hair receptors compared to the
scalp
so it's possible the reason facial hair
doesn't seem to be adversely affected
is because the extra 5a reductase
activity
and higher quantity of angine receptors
makes up for the decrease in dht
also it could be theoretically helped by
the increase in testosterone from using
finasteride
which causes about a 15 percent increase
in testosterone
it might be that the increase in
testosterone increases beard density as
the study indicated but the only change
would be that linear hair growth would
be reduced
so you wouldn't have to shave as often
and it also may take longer to grow a
beard as a result of the reduction in
dht
so anyone looking for an excuse to not
use finasteride
well now you have one fewer excuse
finasteride will not hurt your beard
gains and anyone who has poor facial
hair while on finasteride
likely would have still had poor facial
hair even if they didn't use finasteride
kind of like me
so adolescents who are interested in
finasteride should of course talk to
their doctor just like anyone else
in order to make sure they're finished
with physical maturation before starting
finasteride
but they shouldn't worry about
finasteride affecting their facial hair
development i mean perhaps it will mean
their beard will
grow a little bit more slowly but
testosterone as we've already
established is the hormone
that is responsible for facial hair
development and density not so much so
dht and even still
facial hair is so sensitive to dht uh
due to the high quantity of android
receptors as well as the presence of 5a
reductase
that it may not even matter either way
even if you are on finasteride so
i've also seen some reddit posts where
people say their facial hair slows but
it hasn't decreased in density at all
which is anecdotal of course but
nevertheless corresponds to the research
done
on the subject so in conclusion people
do not have to choose between their
scalp hair and their facial hair
i mean i think a lot of people associate
beard hair with dh
dht just because a lot of bald guys grow
beards but they're just doing that
because they are compensating not
because they're better at growing beards
necessarily
and if you ask me the bald and bearded
look is just really cliched and boring
looking i mean it's such a
dime a dozen look i mean they basically
look like they're just trying to grow
their hair upside down so i can't stand
that look so
no finasteride won't screw up your beard
gains so stop worrying about it
and with that i am out and i'll be back
with more content
soon but keep in mind i'm still doing
some hardcore gaming tonight i'm
fighting soft some mongolian invaders
and goes to tsujima
uh so don't expect me to be too active
tonight but i will be back soon
and see you next time
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