Create your own liposomes

Summary

In this informative presentation, Belinda Carly from the Institute of Personal Play of Science demonstrates how to create personalized liposomes using Pro Lipo Neo. This revolutionary material allows formulators to encapsulate their chosen active ingredients, enhancing product efficacy and bioavailability. Carly explains three methods for incorporating both water-soluble and lipid-soluble actives into liposomes, emphasizing the importance of proper mixing techniques to maintain the delicate structures. By using Pro Lipo Neo, formulators can develop unique skincare solutions that stand out in a competitive market, significantly improving the delivery of active ingredients.

Takeaways

• 😀 Liposomes are microscopic vesicles that enhance the delivery of active ingredients to the skin.
• 🌊 Pro Lipo Neo is a revolutionary material that allows users to create custom liposomes with selected actives.
• 🚀 Active ingredients are only as effective as their ability to reach the delivery site; liposomes improve this process.
• 📈 Pro Lipo Neo can deliver up to 2.5 times more active penetration in almost half the time compared to traditional methods.
• 🧪 The creation of liposomes involves a simple process of mixing water-soluble and lipid-soluble actives with Pro Lipo Neo.
• 🌟 A color change from bright orange-yellow to milky yellow indicates successful liposome formation.
• 💧 Water-soluble actives can be effectively encapsulated in the aqueous core of liposomes, while lipid-soluble actives are incorporated in the bilayer.
• 🔬 Proper stirring equipment and low shear techniques are essential to maintain the integrity of liposomes during product formulation.
• 📦 Customized liposomes offer a unique marketing story and enhance product efficacy, setting brands apart from competitors.
• 🎉 Belinda Carly emphasizes the ease of making personalized liposomes, making it accessible for formulators.

Q & A

What is the main purpose of the presentation?

The presentation aims to demonstrate how to create personalized liposomes using a material called Pro Lipo Neo, allowing for the incorporation of customized active ingredients.

What are liposomes and why are they important in skincare?

Liposomes are microscopic vesicles made of phospholipid bilayers that can encapsulate active ingredients. They are important because they enhance the delivery of these ingredients into the skin, improving bioavailability and effectiveness.

What is Pro Lipo Neo, and how does it work?

Pro Lipo Neo is a ready-to-use mixture of phospholipids that, when activated by water, forms liposomes. This material allows formulators to create their own liposomes with specific active ingredients for tailored skincare products.

How does the effectiveness of liposomes compare to traditional delivery systems?

Liposomes have been shown to deliver up to 2.5 times more active penetration in nearly half the time compared to traditional delivery systems, making them a more efficient option for enhancing product efficacy.

What types of active ingredients can be incorporated into liposomes?

Both water-soluble and lipid-soluble active ingredients can be incorporated into liposomes, allowing for a wide range of formulations that cater to different skincare needs.

What are the three methods demonstrated for creating liposomes?

The presentation outlines three methods: incorporating a water-soluble active, incorporating a lipid-soluble active, and incorporating both types of actives.

What is the significance of the color change observed when creating liposomes?

The color change from orange-yellow to a milky beige indicates that the liposomes have formed successfully, signaling that the encapsulation of active ingredients is complete.

Why is it important to add liposomes to the final product after cooling?

Adding liposomes after cooling is crucial to preserve their delicate structures, which can be damaged by heat and excessive shear during mixing.

What type of equipment is recommended for mixing liposomal formulations?

Low shear mixing equipment, specifically sweeper blades, is recommended to avoid breaking the fragile liposome structures when incorporating them into the final product.

What is the overall benefit of creating unique liposomal formulations?

Creating unique liposomal formulations allows companies to differentiate their products in the market, providing enhanced delivery of actives and a compelling marketing story.