PENGUJIAN KESERAGAMAN BOBOT SUPPOSITORIA | TEKNOLOGI FARMASI - STFI Bandung

Summary

This educational video by Riska Rahmawati provides a detailed guide on performing a weight uniformity test for suppositories (or ovules). Viewers learn the importance of ensuring consistent weight for pharmaceutical quality, with the test criteria outlined: no more than 5% deviation from the average weight and no individual unit deviating more than 10%. The video covers necessary materials, including a digital balance, and demonstrates the process of weighing 10 suppositories, calculating their average weight, and checking for acceptable weight deviations. This instructional content aims to improve testing practices and ensures that pharmaceutical products meet required standards.

Takeaways

• 😀 The video explains a test for uniformity of weight in suppositories or ovula.
• 😀 The purpose of the test is to ensure that the produced dosage forms have uniform weight and do not deviate from the average weight.
• 😀 The required standard is that no more than 2 suppositories should deviate by 5% from the average weight, and none should deviate by more than 10%.
• 😀 The materials used in the test include the suppositories to be tested and a digital balance.
• 😀 The procedure involves weighing 10 suppositories and recording their individual weights.
• 😀 An example weight of a suppository is provided: 15.43 grams.
• 😀 After weighing the individual suppositories, the average weight is calculated, which in this case is 1.54 grams.
• 😀 The deviation for each suppository should not exceed 0.77 grams (5%) from the average weight.
• 😀 No suppository's weight should deviate by more than 1.54 grams (10%) from the average weight.
• 😀 The video concludes with a reminder to ensure the uniformity of the suppository weights and the importance of this test for quality control.
• 😀 The video ends with a friendly goodbye and a thank you to the viewers.

Q & A

What is the purpose of conducting the weight uniformity test on suppositories or ovula?

The purpose is to ensure that the prepared suppositories or ovula have consistent weight and do not deviate from the average weight by more than acceptable limits.

What are the acceptable deviation limits for the weight of suppositories in the uniformity test?

The weight of the suppositories must not deviate by more than 5% from the average weight. Additionally, no suppository should deviate by more than 10% from the average weight.

What equipment is required to perform the weight uniformity test?

The test requires a digital scale and the suppositories or ovula to be tested.

How many suppositories should be weighed in the uniformity test?

Ten suppositories should be weighed during the test.

What is the correct procedure for conducting the weight uniformity test?

The procedure involves weighing each suppository individually and recording the results. The average weight is then calculated, and the deviation of each suppository is compared to the average weight.

How is the average weight of the suppositories determined?

The average weight is determined by summing the individual weights of the ten suppositories and dividing by the total number of suppositories.

What should the weight deviation for each suppository be in relation to the average weight?

Each suppository's weight must not deviate by more than 0.077 grams less or more than the average weight.

What action should be taken if the weight of any suppository deviates more than 10% from the average?

If any suppository's weight deviates more than 10% from the average, it would indicate a failure to meet the uniformity requirements and should be addressed accordingly.

What is the significance of the 5% deviation limit in the weight uniformity test?

The 5% deviation limit ensures that the weight of most suppositories remains close to the average, maintaining uniformity and consistency in the product batch.

What is the expected outcome of the weight uniformity test?

The expected outcome is that all the suppositories will meet the weight uniformity standards, with no deviations exceeding the prescribed limits of 5% for most and 10% for any individual suppository.