PENGUJIAN WAKTU LELEH SUPPOSITORIA | FARMASETIKA - TEKNOLOGI FARMASI - STFI Bandung

Summary

In this instructional video, Fauzan Arung Samudro demonstrates the process of performing a melt time test for suppositories. The test measures how long it takes for a suppository to dissolve completely at body temperature (37°C). Using a disintegration tester, the suppository is placed in a controlled environment, and the time it takes to melt is recorded. This procedure is vital for evaluating the quality and effectiveness of suppository formulations. The video concludes with a reminder of the importance of this test in pharmaceutical assessments.

Takeaways

• 😀 The video introduces the topic of 'melting time test' for suppositories, focusing on its importance in evaluating pharmaceutical formulations.
• 😀 The purpose of the melting time test is to measure the time required for a suppository to fully melt at body temperature (37°C).
• 😀 The test is mandatory in the evaluation process of suppository formulations to ensure their effectiveness in the body.
• 😀 Equipment used in this test includes a disintegration tester, suppository testing rods, and the suppository sample itself.
• 😀 The procedure begins by opening the test rod and placing the suppository sample into the testing tube.
• 😀 After inserting the suppository, the test rod is closed again, and the device is set up for testing.
• 😀 The device should be connected to power, and the temperature is set to 37°C ±1°C.
• 😀 Once the setup is complete, the suppository test rod is placed into the device, and the start button is pressed to initiate the test.
• 😀 During the test, the observer must monitor the suppository and record the time it takes to completely melt in the testing liquid.
• 😀 The video concludes by emphasizing the importance of this test in ensuring the proper function of suppositories when used by patients.

Q & A

What is the main focus of the video?

The video primarily explains the process of testing the melting time of suppositories, a key evaluation step in pharmaceutical preparations.

What does the melting time test for suppositories measure?

The test measures the amount of time it takes for a suppository to fully melt at a temperature of 37°C, which is the average body temperature.

Why is the melting time test important?

This test is crucial for evaluating the quality of suppositories, ensuring that they dissolve properly within the body for effective delivery of medication.

What equipment is required for the melting time test?

The test requires a disintegration tester, test rods, suppository samples, and a water bath set to 37°C.

What is the first step in conducting the melting time test?

The first step is to open the test rod and place the suppository sample into the test tubes.

How do you prepare the equipment for the test?

Ensure that the equipment is connected to electricity, switch on the power, and set the temperature of the water bath to 37°C (±1°C).

What is the role of the temperature in the test?

The temperature of 37°C (±1°C) is used to simulate the conditions of the human body, allowing the suppository to melt as it would when inserted.

What should be done after setting up the equipment?

After setting up, you attach the test rods to the equipment, insert the test tubes, and then press the start button to begin the test.

What do you need to observe during the test?

You need to observe how long it takes for the suppository to completely melt in the testing solution.

What is the final step in the test procedure?

The final step is to record the time it takes for the suppository to fully dissolve in the test solution.