Penentuan Kadar Sulfadiazin secara Nitrimetri

Summary

The transcript outlines a comprehensive laboratory procedure focusing on the preparation of various chemical solutions. It covers the preparation of KI, starch solution as an indicator, and NaNO2, as well as the titration of sulfadiazine using NaNO2 in the presence of starch. The process includes precise measurements, dissolutions, heating, and titrations, with the aim of determining the concentration of sulfadiazine in tablets. The steps are meticulously performed, ensuring accurate results, with multiple titrations and repeated experiments to ensure reliability and consistency of the findings.

Takeaways

• 😀 The script describes the preparation of a 0.1% KI solution by dissolving 0.4g of KI in 100ml of distilled water.
• 😀 It involves the careful weighing of the KI and the glassware, and washing the glassware to ensure no residue is left behind.
• 😀 The script also covers the creation of a starch solution as an indicator, which is prepared by dissolving 0.5g of starch in 100ml of distilled water.
• 😀 The starch solution is heated for around 5 minutes, filtered, and then diluted with the KI solution to reach 100ml.
• 😀 After the starch solution is filtered and cooled, it is used for titration with a 0.1M sodium nitrite solution.
• 😀 The titration process involves slowly adding sodium nitrite and observing the color change on starch paper to determine the endpoint.
• 😀 Titration is continued with 0.5ml increments of sodium nitrite until the starch paper turns blue, signaling the endpoint.
• 😀 The script describes precise steps for preparing other solutions, including the sodium nitrite solution, which is carefully prepared to 0.1M concentration.
• 😀 It emphasizes the importance of labeling and storing the prepared solutions correctly to avoid contamination or mix-ups.
• 😀 A key focus of the script is the use of sulfadiazine tablets, which are weighed and titrated in a similar manner to determine their concentration using the starch indicator.

Q & A

What is the first step in preparing the KI 0.1% solution?

The first step is to weigh the KI (potassium iodide) using a watch glass. The initial weight of the watch glass is 12.7 grams, and the total weight of the watch glass plus KI is 13.1 grams.

How is the KI solution prepared after weighing?

After weighing the KI, it is transferred into a 100 mL beaker glass. The watch glass is rinsed with aquades (distilled water) to ensure all KI is transferred. The solution is then stirred until the KI is fully dissolved.

What is the next step after preparing the KI solution?

After the KI solution is prepared, the volume is adjusted by adding aquades until it reaches the 100 mL mark. The beaker is then labeled appropriately.

How is the starch paper used in the experiment?

The starch paper is used as an indicator in the experiment. Initially, it is weighed, and then a 0.5g of powdered starch is added to it. The starch is dissolved in 100 mL of aquades and stirred until homogenized.

What happens after the starch solution is prepared?

Once the starch solution is prepared, it is heated for about 5 minutes, then cooled by running water. After cooling, the solution is filtered to remove any solid particles.

What is done after the starch solution is filtered?

After filtration, the starch solution is diluted with KI 0.1% solution in equal volume (100 mL) and stirred to ensure complete mixing. A piece of starch paper is then dipped into the solution to check for color change.

How is the starch paper dried?

The starch paper is removed from the solution and allowed to dry by air drying.

What is the procedure for preparing the NaNO2 solution?

The NaNO2 solution (0.1 M) is prepared by weighing NaNO2 and dissolving it in aquades until it reaches a total volume of 100 mL. The solution is homogenized and the watch glass used for weighing is rinsed with aquades to remove any residual NaNO2.

What is the procedure for titration in the experiment?

The titration is performed by slowly adding NaNO2 solution (0.1 M) to the mixture while observing the color change on the starch paper. Each addition of NaNO2 (0.5 mL) is followed by checking if the starch paper changes to blue. The titration continues until the starch paper turns blue.

What is the significance of the blue color on the starch paper?

The appearance of a blue color on the starch paper indicates the endpoint of the titration, which is reached when all the available iodine has reacted with NaNO2.