Newly Discovered Cause of Insulin Resistance is Not Sugar or Saturated Fat - Dr. Venn Watson
Summary
TLDRIn this enlightening discussion, Dr. Stephanie Vin Watson reveals a groundbreaking study identifying a new nutritional deficiency syndrome, cellular fragility syndrome, linked to C15 fatty acid deficiency. The deficiency is associated with accelerated aging and increased risk of diseases like type 2 diabetes, heart disease, and fatty liver disease. Discovered through research on Navy dolphins, the syndrome is tied to ferroptosis, a form of cell death involving lipid peroxidation and iron. The conversation highlights the importance of C15 in cell membrane stability and the potential of supplementation and dietary changes in addressing this deficiency.
Takeaways
- 🧠 The script discusses a new study revealing a nutritional deficiency syndrome called 'cellular fragility syndrome' linked to C15 deficiencies.
- 🩸 The deficiency is connected to the weakening of cell membranes, accelerated aging, and a higher risk of diseases like type 2 diabetes, heart disease, and fatty liver disease at a younger age.
- 🧬 A decrease in C15 levels in cell membranes is associated with faster cell aging and the onset of aging-associated diseases.
- 🐬 The discovery was made through research on Navy dolphins, which showed signs of diseases typically seen in older age due to low C15 levels in their diet.
- 🔬 The study suggests that ferroptosis—a type of cell death involving iron and reactive oxygen species (ROS)—plays a role in the development of these diseases, especially when C15 is deficient.
- 🌐 The problem of C15 deficiency is widespread, particularly in developed countries, and is linked to modern dietary changes and agricultural practices.
- 🥛 Sardinia is highlighted as a region with unusually high life expectancy and lower rates of heart disease, possibly due to traditional diets rich in C15 from sheep and goat dairy products.
- 🧀 The script emphasizes the importance of C15 in dairy products, especially those from grass-fed animals, which have higher C15 content compared to grain-fed counterparts.
- 🌿 The potential solution includes supplementing with pure C15 to overcome dietary deficiencies and the challenges of modern food production.
- 👶 There is a call to action for the inclusion of C15 in infant formulas and a reconsideration of dietary guidelines regarding dairy fat for children.
- 🔗 The script concludes with the need for further research, awareness, and practical solutions to address the C15 deficiency and its global health implications.
Q & A
What is the primary issue discussed in the interview?
-The primary issue discussed in the interview is the discovery of a new nutritional deficiency syndrome called cellular fragility syndrome, which is linked to a deficiency in C15 fatty acids and is associated with various health problems such as insulin resistance, metabolic syndrome, and increased risk of heart disease, stroke, and type 2 diabetes.
What is cellular fragility syndrome?
-Cellular fragility syndrome is a newly discovered deficiency syndrome caused by a lack of C15 fatty acids in cell membranes. This deficiency leads to weak cell membranes, accelerated aging, and an increased risk of various diseases, including type 2 diabetes, fatty liver disease, and heart disease.
How does C15 deficiency impact the liver and pancreas?
-C15 deficiency leads to lipid peroxidation and iron deposition in the liver, causing liver cells to become weak and not respond appropriately to glucose, leading to insulin resistance. In the pancreas, iron deposition affects beta cells, reducing insulin production, which further exacerbates metabolic issues.
What is the role of lipid peroxidation in cellular fragility syndrome?
-Lipid peroxidation occurs when fragile fatty acids in the cell membrane are exposed to oxygen, leading to damage. This process, combined with iron deposition, results in the production of reactive oxygen species (ROS), which can damage cell components, including mitochondria, contributing to cell death and the onset of diseases.
What is the significance of the discovery of cellular fragility syndrome?
-The discovery of cellular fragility syndrome is significant because it identifies a new nutritional deficiency that can be detected and corrected. Understanding and addressing this deficiency could help prevent or mitigate the development of various aging-associated diseases.
How does the study of Navy dolphins contribute to the understanding of cellular fragility syndrome?
-The study of Navy dolphins, which showed signs of liver disease, insulin resistance, and fatty liver disease, led to the discovery of C15 deficiency as a key factor. This provided a clean model to understand the pathophysiology of the syndrome and the role of C15 in cellular health.
What is the connection between C15 deficiency and ferroptosis?
-C15 deficiency is linked to the initiation of ferroptosis, a form of cell death characterized by lipid peroxidation and iron deposition. The deficiency leads to fragile cell membranes, which in turn triggers the ferroptosis process, contributing to various diseases.
What are the dietary sources of C15 fatty acids?
-C15 fatty acids are primarily found in dairy fat, particularly in milk from grass-fed animals. The type of dairy, such as sheep and goat milk, and the diet of the animals (e.g., grass from high altitudes) can significantly influence the C15 content.
Why is Sardinia mentioned in the context of C15 and longevity?
-Sardinia is noted for its high levels of longevity, and one factor contributing to this is the consumption of dairy products rich in C15, such as peino cheese. The high C15 content in their diet is thought to support cellular health and contribute to their longevity.
What are some potential solutions to address C15 deficiency?
-Potential solutions include dietary changes to increase the intake of C15-rich foods, supplementation with pure C15, and possibly the fortification of foods with C15. Additionally, changes in agricultural practices to increase C15 content in dairy products could be beneficial.
Outlines
🧠 Cellular Fragility Syndrome and Metabolic Disorders
The paragraph discusses the onset of insulin resistance and metabolic syndrome due to iron deposition and lipid peroxidation in the liver and pancreas. Dr. Stephanie Vin Watson introduces a new study on a nutritional deficiency syndrome called cellular fragility syndrome, linked to C15 deficiencies. This syndrome is characterized by weak cell membranes due to the type of fatty acids present, leading to faster aging and increased risk of diseases like type 2 diabetes, heart disease, and fatty liver disease. The discovery is significant as it is the first nutritional deficiency syndrome identified in over 75 years, and it is both detectable and fixable.
🔬 The Discovery of Cellular Fragility Syndrome
This section delves into the discovery of cellular fragility syndrome, which is attributed to C15 deficiencies. The guest explains that cell membranes, made of lipids, can become weak based on the fatty acids present, and this weakness can lead to faster aging and various diseases. The conversation highlights the importance of C15 in maintaining cell membrane integrity and the connection between C15 deficiency and the acceleration of aging-associated diseases. The discussion also touches on the process of ferroptosis, a new way cells were found to die, which involves lipid peroxidation and iron, leading to reactive oxygen species that damage mitochondria.
🐬 C15 Deficiency and Its Impact on Health
The paragraph focuses on the research journey that led to the discovery of C15 deficiency's role in various health issues. It starts with the observation of health issues in Navy dolphins, which were found to have liver disease, insulin resistance, and fatty liver disease at a younger age. Metabolomics was used to analyze the dolphins' diet and bodies, leading to the identification of C15 as a key predictor of health. The lab studies showed that C15 helps mitigate the components of ferroptosis, including stabilizing cell membranes, reducing lipid peroxidation, and repairing mitochondria. The conversation also points out the global decrease in C15 intake due to changes in diet, particularly the reduction of dairy fat consumption.
🌐 The Global Implications of C15 Deficiency
This section discusses the widespread impact of C15 deficiency, drawing connections between the deficiency and the rise of diseases like type 2 diabetes, heart disease, and fatty liver disease at a younger age. The guest explains that the deficiency is not limited to any specific region but is a global issue, particularly in developed countries. The conversation emphasizes the need for increased awareness and action to address the deficiency, including the potential for supplementation and dietary changes to increase C15 intake.
🧴 The Role of Dairy Fat in C15 Intake
The paragraph explores the relationship between dairy fat consumption and C15 intake. It explains that dairy fat, particularly from grass-fed animals, contains higher levels of C15, which is essential for health. The guest discusses the findings from a panel of experts in dairy fat and nutrition who concluded that while whole dairy fat does not reliably improve health, individual nutrients within dairy fat, such as C15, can be beneficial when isolated from the fat matrix. The conversation also touches on the challenges of achieving Sardinian levels of C15 intake through dairy consumption alone.
🌿 Sardinia's Unique High C15 Intake
This section highlights the unique dietary habits of Sardinia, which is known for its high levels of longevity. The guest discusses how the traditional Sardinian diet, rich in dairy from goats and sheep that graze on mountainous grass, contributes to higher C15 levels. The conversation delves into the types of cheese consumed in Sardinia, such as Peino cheese, which has high C15 content, and the potential for increasing C15 levels in dairy through changes in agricultural practices.
🚀 Solutions to Address C15 Deficiency
The paragraph outlines potential solutions to the C15 deficiency problem. The guest discusses the development of a pure C15 ingredient as a supplement and the potential for fortifying foods with C15. The conversation also considers the importance of education and awareness about C15 and the need for further research and global cooperation to address the deficiency.
🧪 Measuring C15 Levels and the Future of C15
This section discusses the availability of tests to measure C15 levels in the body and the future prospects of C15 as a key nutrient. The guest talks about the partnership with gova Diagnostics to create an at-home spot test for C15 and the importance of understanding individual C15 levels. The conversation also looks forward to the potential fortification of foods with C15 and the role of supplementation in addressing the deficiency.
Mindmap
Keywords
💡Iron deposition
💡Lipid peroxidation
💡Cellular fragility syndrome
💡C15 deficiency
💡Ferroptosis
💡Insulin resistance
💡Metabolic syndrome
💡Sardinia
💡Reactive oxygen species (ROS)
💡Mitochondria
Highlights
Iron deposition, lipid peroxidation, and ROS (reactive oxygen species) in the liver can lead to insulin resistance and the onset of metabolic syndrome.
A new nutritional deficiency syndrome, Cellular Fragility Syndrome, has been discovered after 75 years, linked to C-15 deficiencies.
C-15 fatty acid deficiency in cell membranes can cause cells to age faster, potentially explaining the rise of aging-associated diseases in younger populations.
Ferroptosis, a newly discovered cell death mechanism involving lipid peroxidation and iron, is linked to C-15 deficiency.
C-15 deficiency is associated with the pathophysiology of metabolic syndrome, including insulin resistance and glucose imbalance.
The study suggests that increasing C-15 levels could potentially mitigate the effects of ferroptosis and related diseases.
The research was triggered by a syndrome observed in Navy dolphins, which led to investigations into C-15's role in cellular health.
C-15's importance in cell membrane integrity and its potential to reverse cellular fragility syndrome has been demonstrated through various studies.
The Sardinian population's high C-15 intake from specific types of cheese may contribute to their longevity and lower incidence of heart disease.
Sardinians consume a diet rich in C-15 from sheep and goat dairy, which may be a model for addressing the global C-15 deficiency.
The consumption of dairy products with higher C-15 content could be a strategy to increase C-15 levels in populations with deficiencies.
The development of a pure C-15 supplement provides a potential solution for increasing C-15 intake, especially for those with vegan diets.
C-15's stability as a powder at room temperature makes it suitable for food fortification to address the deficiency globally.
A new at-home test for C-15 levels has been developed, allowing individuals to monitor their C-15 status.
The study emphasizes the need for a multi-faceted approach to address the C-15 deficiency, including dietary changes, supplementation, and potential food fortification.
The research highlights the importance of C-15 in early development, suggesting that maternal C-15 levels may impact cognitive development in children.
Transcripts
when you have iron plus Ross right and
lipid peroxidation all happening first
in the liver the liver will stop um
producing uh the appropriate amount of
or it won't react appropriately to
glucose so you start getting the onset
of insulin resistance happening at the
liver side basically just because you
have broken liver cells in which the
liver is not responding appropriately to
basically keeping our glucose balanced
at the same time once iron deposition in
this whole process starts happening in
our pancreas our beta cells stop
producing insulin so we've got kind of a
one two hit of both our pancreas and
liver and when you combine those that
then sets you up for metabolic syndrome
right which is this High um insulin or
insulin resistance high glucose you get
this middle um you know
atopos uh a weight gain and then that
all sets you up for an increased risk of
heart disease stroke um and type two
diabetes Dr Stephanie Vin Watson I had
you on earlier this year but there's
this brand new study that just came out
so it was absolutely worth bringing you
right back on to talk about this so
without further Ado let's just jump
right into this because this is I'm
going to let you explain the science
I'll ask some questions because this is
one of the coolest studies that I've
seen this year great then well thanks
Thomas well so we discovered the first
nutritional deficiency syndrome in over
75 years so you think about things like
vitamin C and scurvy and vitamin D
deficiency in rickets we have discovered
a deficiency syndrome uh thanks to c-15
deficiencies and it's called cellular
fragility syndrome and so it's a giant
Discovery and what's so wonderful about
discovering a nutritional deficiency
even though you know it sounds
devastating is that this is something we
can detect Thomas and something we can
fix so so excited to be able to be here
to talk about this discovery and you
know what it means for all of us what
exactly is cellular fragility so yes
when we talk about you know our bodies
are made out of cells so everything
every part of us is made out of cells
and our cells are armored by these cell
membranes and so the cell membranes are
made out of lipids and they can become
weak and what we've learned is that
based upon the type of fatty acids in
the cell membrane dictates how strong or
weak our cells membranes are and why do
we care about that well it's because
when our cells become weak they undergo
faster aging so basically they fall
apart a lot faster they age faster that
translates to us aging faster and so
what's so important about this discovery
is we've learned that over the past 12
years of research not just us but others
around the world that if we don't have a
certain level of C15 in our cell
membrane this sturdy saturated fatty
acid in our cell membrane our cell
membranes become weak we age faster than
we should and we now think it may
explain the onset of these aging
Associated diseases things like type 2
diabetes fatty liver disease heart
disease are increasing in younger and
younger people and now we think that the
c-15 deficiency syndrome cellular
fragility syndrome may be the cause of
why younger and younger people are
getting older diseases is it just
because the the cell becomes more like
penetrable to like all these different
things like how does how does that
really work how does a fragile cell
membrane
impact say like insulin resistance
things like that where's the interplay
there yeah so it's a fascinating story
and it goes back to 2012 so back in 2012
there was a group of scientists at
Columbia University and they published
this paper in which they discovered an
entirely new way that our cells were
dying and it's called ferroptosis or
fosis we just say if you're in England
it's for oposisi
but the key point being that these
researchers discovered entirely new way
our cells were dying prior to this
discovery there were only three known
ways that our cells could die called
apoptosis necrosis and autophagy and
this was just like you go to cell
biology class you know at your
University three ways our cells die
great they discovered a fourth and what
was really interesting about it is that
they discovered that there was a really
unique way that our cells were starting
to die and it started with l literally
the way they explain it is that there's
fragile fatty acids in the cell membrane
that then results in um lipid
peroxidation so lipid peroxidation is
when you have fragile fats they then go
bad so they get um exposed to oxygen
attack by oxygen they get lipid
peroxidation so now you have that and
then for some strange reason iron is
showing up inside of these cells and
when you combine lipid peroxidation with
iron that results in massive production
of these things called reactive oxygen
species or Ross the Ross then go and
kill our mitochondria and as we all know
right from our third grade classes
mitochondria is the PowerHouse of our
cells that knocks out our mitochondria
because I learned that like 10th grade
I'm sorry okay so I'm a nerd so yeah
yeah I know you and Eric just worked out
uh and I stood on the sideline so that
the nerd part was the
mitochondri um so uh yeah so powerhouses
of our cells so basically then knocks
out the batteries the energy producers
of our cells so when these scientists
were looking under the microscope at
Columbia University Thomas they were
seeing intact cells with kind of Strang
looking cell membranes and all the
mitochondria were killed and so they
said this cell is dead what is happening
that was discovered discovered in 2012
since then over
10,000 papers have been published
published on fosis from around the world
nobody has UND despite all that science
nobody has understood what causes froses
why did it show up on our doorstep right
about you know a dozen years ago and um
you know until now so now what we're
finding is that C15 deficiency what this
paper that we just published showed that
C15 deficiency is causing the beginning
the middle and the end of for Tois most
importantly we've been able to show that
putting c-15 back into our bodies fixes
it all so really exciting times so with
this uh study in particular like how was
it laid out what did it uh what exactly
how did you discover this deficiency
specifically with regard to this paper
yeah absolutely so it's really a
culmination of the 12 years of study so
the same year 2012 when fosis was
discovered by Columbia University which
you know to be honest I didn't know
about for many many years at the same
year that paper is published we
published a paper describing the strange
disease that was popping up in the
Navy's dolphins and dolphins in the wild
as well but increasingly there was this
liver disease that was popping up in
Navy dolphins and they had iron overload
in their livers and they were getting
fatty liver disease and insulin
resistance and things that older
Dolphins we get but we were starting to
see it in younger and younger Dolphins
so we were diving in to basically figure
out what was happening with the dolphins
what was causing it that's when we did a
advanced technology called metabolomics
we looked at thousands of small
molecules in their fish diet and in
their bodies to figure out which small
molecules predicted this syndrome that
we were seeing and that's where C15 was
one of the top predictors of dolphins
who weren't getting this disease so that
headed us down this pathway of taking
c-15 into the lab we were then able to
show um in the lab that c-15 helps to
fix all components of fosis it
stabilizes cell membranes by greater
than 80% so it you know stops it right
at the top of the problem it um
decreases lipid peroxidation it stops
iron deposition so we'll talk a little
more about that um which is another
obviously key parts of ferroptosis the
Ferro being iron um it stops the
deposition of the iron
it decreases the amount of reactive
oxygen species in the cell and it
repaired mitochondria so that whole
series of studies we published back in
2020 in the paper uh and scientific
reports and so really what's been
happening since 2020 is it's been uh
understanding more and more of what's
been happening in people that has
overlaped with what's happening in
dolphins and US understanding oh my gosh
it's a decrease in c-15 globally that's
happening in the Dolphins it's because
the types of fish they were eating are
have less and less C15 in it as our
waters are getting warmer unfortunately
our fish are getting less fat there's
actually a study that just came out in
science showing that the world's fish
are getting smaller because the waters
are warmer so they have less fat L C5 to
the Dolphins for us we have less C15
globally we've been doing so for over 50
years by taking c-15 out of our diets
because our primary source of c-15 is
dairy fat so we had this concurrent uh
you know coincidental decrease in c-15
in diets happening in dolphins and
humans the result however was the same
which was F
oposisi deficiencies that's so wild so
what I do know about ferroptosis I mean
a lot of it is it's iron deposition in
the liver specifically there's a like
one of the big components of it right
that's right so is that just sending
like a Cascade of high levels of of Ross
directly from the liver epicenter out of
the liver and kind of radiating out from
there or is it just concentrated in the
liver or is ferroptosis occurring
independent of the liver is it not just
happening there I mean and you may or
may not know this but what's actually
causing the iron to just deposit there
like why is it flocking to the liver and
why is it just because it's trying to
get metabolized I don't know I have
questions there yeah it's a it's a those
are all great questions so um and that's
what's been kind of hanging out there
it's like what how is this all happening
right and so it's almost like science
has gotten stuck in the weeds of looking
at specific genes and little triggers
inside the cell meanwhile we had this
like real life patient population that
was getting the syndrome you know the
Dolphins and we were really able to
understand exactly cleanly how this goes
down so um what we Now understand is
What's called the pathophysiology so the
whole thing of how c-15 deficiencies
lead to this entire syndrome and it all
starts with when we have low C15 in our
cells that includes our red blood cells
so let's start with our red blood cells
so then those red blood cells become
weak now our body has a really good way
of detecting weak red blood cells and
saying uh you shouldn't be in the system
anymore we're going to take you out so
you have these cells in the liver called
macroasia and their job is to basically
engulf and eat all the weak red blood
cells that we have in our body which
normally is a good thing
but what happens when we have a lot of
weak red blood cells because we have two
little C15 in those cells the macras
just eat them and the corpses of the red
blood cells that are left behind ah IR
kind iron yep yeah so what happens is
then it accumulates over time our bodies
are still able to make these red blood
cells so they get taken out of the
system we make more so you know when you
don't necessarily have anemia in the
early stages but there is a measurement
called red blood cell distribution width
or RDW and it's one of the first things
we saw in the Dolphins which just means
that your red blood cell sizes are just
there's a lot of variation there's some
big ones some little ones it just means
that your body's working you're losing
red blood cells you're making them and
you just have this mix of sizes so it's
one of the first hints of um something
is going wrong and RDW is actually a
predictor of longevity um in people so
we can get back to the whole longevity
conversation so it's a fascinating
metric that's gained a lot of traction
so again we think it's all tied to this
pH proptosis so the um red blood cells
become weak the iron or the the liver
engulfs them you now have iron
deposition in the liver you now have an
angry liver so now we're talking about a
liver that's getting increased iron and
along with these fragile cells in the
liver as well so you have lipid
peroxidation iron faptos has now kicked
in in the liver so then what happens is
the next um signal and sign are elevated
liver enzymes so the liver is now saying
hey I'm getting a little bit angry here
cuz my cells are getting injured and
that's one of the first signals they
throw off um from there then just like
you were kind of getting to right is
that what happens is when you get enough
iron overload in the liver you get a
spillover effect you have increased Ross
you have increased lipid peroxidation
you have increased iron that iron lipid
peroxidation and reactive oxygen species
spill over into the blood and now they
start seeding our whole bodies so it
goes through these different stages and
that's where now there's tons of papers
talking about iron deposition in the
brain in the heart in the pancreas and
that's those are drivers for Alzheimer's
disease heart disease um type 2 diabetes
in addition to the initial liver disease
so that's how we clearly understand it
all happens we've been able to show that
c 15 reverses this entire process and it
starts at the very beginning we just
need to have stronger cells that stops
this whole process from kicking off it's
like the uh it's like the Roman Empire
like starting in Rome the like the liver
and like creating these little Depot
everywhere else that then from there
like cause problems there you know in
the heart and the brain and whatnot
because it's like it sounds like
everywhere you have a potential iron
deposition you have like another Factory
for Ross right you have another because
it's like the more oxidation that
happens there the more it's going to be
exacerbated in that area that's right
how does that particularly like with the
the Ross and the iron depositions how
does that relate to metabolic disease or
metabolic dysfunction like specifically
with like insulin resistance like how
does high a high level of Ross or a high
level of iron deposited somewhere impact
insulin resistance because I think for
most people that's a that's a hard thing
to bridge right it's like okay we've got
Ross but how does that impact glucose
and my you know that yeah absolutely so
so we now understand we now know that
when you have iron plus Ross right and
lipid peroxidation all happening first
in the liver the liver will stop um
producing uh the appropriate amount of
or it won't react appropriately to
glucose so you start getting the onset
of insulin resistance happening at the
liver side basically just because you
have broken liver cells in which the
liver is not responding appropriately to
basically keeping our glucose balanced
at the same time once iron deposition
and this whole process starts happening
in our pancreas our beta cells stop
producing insulin so we've got kind of a
one two hit of both our pancreas and
liver and when you combine those that
then sets you up for metabolic syndrome
right which is this High um insulin or
insulin resistance high glucose you get
this middle um you know
atopos uh a weight gain and then that
all sets you up for an increased risk of
heart disease stroke um and type 2
diabetes where we caught the Dolphins
was right at that stage of um basically
metabolic syndrome before it had
Advanced to these Advanced um you know
conditions so it was really at the
perfect spot to understand the
pathophysiology leading to that wow so
does a c-15
deficiency are you starting to see
direct links maybe not like right now
it's easy to say there's a potential
indirect direct link because you've got
the metabolic piece and that could
affect cardi metabolic and you know
cardiovascular disease and whatnot are
there any signs that there's direct
links with c-15 deficiency and fer
ferroptosis and cardiovascular disease
like independent of the metabolic side
yeah there is so with regard to you know
the Dolphins were an interesting and
again a clean model in which because
they weren't getting enough c-15 in
their diet because the fish had less C15
that we were able to see this we were
able then to repeat this in the lab so
to be able to show directly that there
are models of ferroptosis that then we
could show that c-15 could fix it so
we've got you know the side that the
Dolphins are indicating c-15
deficiencies cause it um able to show in
a model that c c-15 fixes it so then we
start moving to the human data right and
this is where we see um where we explain
in the paper um which is a beast of a
paper so if you're trying to
sleep that could help you sleep just by
trying to get through this paper so but
what it Works through this um uh logical
um arguments with regard to okay what is
faptos is known to do it is known to um
increase our risk of heart disease um
type 2 diabetes and fatty liver disease
it's really what we focus on not only
does it increase the risk of it but it
speeds up the onset of these diseases
and it makes it more aggressive so if we
talk about younger people so people with
um younger kids um people less than 20
years old getting type 2 diabetes right
so type two diabetes used to be an adult
onset disease and we used to call type 1
diabetes juvenile onset remember that
okay so at some point in time about when
all of this started happening children
started getting type two diabetes and
not only that but they're more
aggressive than the type two diabetes
that we're used to seeing they have a
higher risk rate and of complications in
even kids with type one diabetes which
that in itself is a devastating disease
so ferroptosis in this process is
showing up in younger people it's
explaining how they're getting more
aggressive diseases faster um people
between 18 to 44 year old uh 44 years
old increasingly getting coronary heart
disease I mean we were on an amazing
trajectory of decreasing heart disease
for decades still is the same case for
people over 50 so like I'm in the clear
but but for younger people The increased
risk of of um heart disease is has been
going way up when I get back to Ty type
2 diabetes 673 per increase is expected
in young people um by the year 2030 in
typ D IB so it's really and then we talk
about fatty liver disease right this is
a disease that didn't exist before a
paper was published by uh the Mayo
Clinic in 1980 they found the first 20
patients with fatty liver disease um
that wasn't associated with alcohol
right prior you see this disease it was
always associated with alcohol
consumption which is why they called it
non-alcoholic fatty liver disease or
non-alcoholic stat of hepatitis so Mayo
Clinic publishes this uh you know first
20 cases in 1980 today it's now
impacting one in three people globally
and one in 10 children so there's this
been this big mist of how is it
happening we're all understanding that
fosis is driving this process and this
speed up of the of the problem and now
it's being able to say okay um the
study's now linking showing people with
higher c-15 levels lower risk of type 2
diabetes heart disease and fatty liver
disease and this isn't just one study or
two study these are a
metaanalyses um of you know thousands of
people over Decades of time consistently
showing how much basically you know c-15
we need in order to protect against um
getting these diseas
I mean it's almost like we've been
looking at so many things in isolation
which we we should but at the same time
I mean it sounds like it's accelerated
aging is like really what's happening
it's like we're just finding that like
people at a younger age are experiencing
problems that shouldn't be an issue
maybe at all but are you know previously
an issue when they're over 50 60 years
old and it's like everything's just
accelerating so it's like okay here we
are looking at these sole things okay
like cardiovasculares or Diet diabetes
but we're not looking at dare I say the
root I hate when people say the root
because it sounds kind of cheesy but
it's like okay like the root really
seems like okay we're just moving
through this so fast and I'm kind of
thinking again like an iron deposition
and reactive oxygen
species it's Death By A Thousand Cuts
it's like you've got an iron deposition
I know we've talked about this before
but like you leave you know a bunch of
anvils or a bunch of dumbbells out in
the elements right it's like okay if you
had a little bit of oxygen they would
rust and they would you know have a
problem a little bit of the elements
they would have a problem but as the
weather gets worse it would just it
oxidize even more right so it's like
okay sure the iron deposition as a
result of this deficiency is problematic
but then you combine that with the
crappy lifestyle and it's like almost
literally throwing gasoline on this fire
right it's just it's just GNA take off
from there yeah that's exactly it I mean
examples include you know as far as you
know when you talk to pediatricians
these days and especially like we work
with Dr Jeff Schwimmer he's one of the
leaders in pediatric fatty liver disease
and you know we talked about and we
brought up this idea of like accelerated
aging and kids and like I didn't even
get to finish the sentence he's like oh
no this is absolutely what's happening
like kids are getting the diseases of
their grandparents before their parents
get them he's like it's unquestionable
there's accelerated aging happening in
these kids it's not only impacting their
kind of like you see them getting high
blood pressure and high cholesterol I
mean it's just you know it's and he goes
and there are you know mental health um
problems that are coming with it it's
like you know there's just this giant
you know ball of twine that is just like
that they're getting caught up in so
there isn't C15 is not like oh and
that's it and that's the only problem
and that you know it's but a lot of it
as far as you know when we look back and
you look back at what is causing this
why are younger people getting these
diseases a lot of people fall back on
Obesity well it's like well you know
kids are more obese and this is what
happens with obesity and it's a pretty
simple problem they also talk about
trans fats or there's too much ultr
processed foods and those are all likely
contributors to the problem but for us
it's like we go back to the Dolphins
yeah and the Dolphins aren't obese they
aren't getting you know Ultra processed
foods and they're not eating a bunch of
trans fatty acids so for them they again
provided this amazingly clean picture of
they decreased their amount of C5
we can now quantify how much C15 needs
to be in those cells it's
0.2% of fatty acids in our cell membrane
we need at least that for that cell
membrane to stay intact you have less
C15 than that and that is now what we're
defining as nutritional deficiency
syndrome or now makes a lot of sense
cellular fragility syndrome so the good
thing is we can now measure and detect
how much is in there and then you know
detect who has the deficiencies and most
most importantly how to fix it how can
we get our world back to where we could
have these healthy cells um that are
meant to Keep Us Alive and long and
healthy for a long long period of time I
don't know if you know listeners
understand the the magnitude because it
took me a long time to like understand
the magnitude of like what a true
clinical deficiency is like we haven't
had a clinical deficiency that we could
say is a legit clinical deficiency
people say oh I'm deficient in vitamin B
because I'm you know vegan or whatever
like it's not a clinical deficiency like
first of all like a lot of the
deficiencies we talk about are is
guesswork it's not we can assume or we
can get a micronutrient panel and see
that we're moderately deficient in
something but a clinical deficiency like
a real deficiency that's big news and
that's you know why this paper is is the
real deal to actually demonstrate that
we're seeing widespread like this is a
legit deficiency just like vitamin C
deficiency causes scurvy just like like
the real deal yeah I mean it's what was
critical for this paper was to be able
to define the pathophysiology of it so
you can't just say oh this is a normal
you know bell curve for c-15 levels in
people and if you have the low level
you're deficient right it's like no it's
like it's like it's a nutritional
deficiency requires one that the thing
that you're calling deficient that
nutrient has to be essential so it means
that we have to get certain amounts our
body has to have certain amounts of it
in order to just maintain Baseline
health and in the absence of it we fall
apart right and that's very very rare so
we're talking about our vitamins right
so vitamin C vitamin D um and then the
second part is that not only proof that
if levels are low you develop a disease
because of those levels but when you
restore that nutrient back into the
system that then that specific
deficiency syndrome is fixed and so
that's what this paper goes in
incredible detail has 150 um or 142 uh
references I've been up for six
days let get your highlighter out but
you know so it's um that it goes into
detail of basically checking off all of
those boxes um where you know it's it's
now it's it is well defined it is shown
that it's caused by um deficiencies in
C15 it is fixed by C15 it's very
definable and this all of this showed up
for oposisi aging all of it showed up at
the same time we've been taking c-15 out
of our diets so this you know experiment
uh that we've done over the last 50
years um
unintentionally um for bad reasons um
you know has by taking C15 out of our
diets we've basically you know tested
the hypothesis of is C15 really an
essential fatty acid um which is what we
discovered you know back in 20 I want to
talk about Sardinia for a second because
like Sardinia is very interesting anyway
from a longevity perspective I've done
pretty detailed videos on just multiple
aspects I mean ranging from like the The
Grapes grown at high altitude for the
specific wine the mastic oil um even
Mastic Gum like other components of
their diet like a lot of dairy from
sheep a lot of like very interesting
diet and in isolation like Sardinia is
one of the most unique blue zones to
begin with like it's it has its own
outlying aspects of it that are
different from the other blue zones
independently and I don't want to you
know go off on my own like high horse
about it but it's just so interesting
like you protein consumption is a little
bit higher in Sardinia than a lot of the
other ones and um and you mentioned
something before we were filming about
Sardinia that I didn't know and that was
about a specific kind of cheese that
they eat there and I want to kind of
double down on that cuz that's really
interesting can you tell me a little bit
more about that yeah absolutely so so
you know Sardinia is FC you're correct
very fascinating um with regard to uh
you know it's one of the five longevity
blue zones as you mentioned Thomas and
so with Sardinia the other thing that's
unique about it you know because it's
called the island of centenarians right
where people are most likely to live to
100 years old and specifically men so
this actually has the largest population
or relative population of Long lived
centenarian men of anywhere in the world
even normally women live longer yeah
exactly so it's like oh so something
you're right that something is very
unique of what's happening in Sardinia
so as we were going through the papers
and working through okay what are normal
levels of c-15 because we what we do in
the paper is we help Define nutritional
deficiency you know what's low what's
normal and now what may be optimal C15
level so we have the opportunity here to
maybe not just get back to where we were
to healthy levels levels where our cells
keep us healthy the way nature intended
for maybe most of us but Sardinia is
providing a clue that there may be a way
that if we push c-15 levels even higher
we can actually help support longevity
and so with Sardinia they have levels so
on average um the average person today
has c-15 levels in their cell membranes
of 0 2% of total fatty acids which is
right that breaking point it's like you
may or may not get disease WEA you're
you know on either side of that 0 2% in
Sardinia even as you look at the older
people and our C15 levels naturally
decline as we get older right so we're
talking 0 2% in your average aged
population so in Sardinia they looked at
60 to 75 year olds and they have C15
levels of 64 so so more than three times
higher C5 levels were like what and this
paper came out from M at all showing and
where they called out hey people in
Sardinia have very high C15 levels and
so when we looked into that and then we
even when they get to 80 to 100 it does
go down as they age but even the 80 to
100 pluss still have 0.4% and when they
compare that to low longevity Zone I
shouldn't even put in quotes to a low
longevity Zone the low longevity Zone
had 2% so basically the world is in a
low longevity Zone C15 level so when we
get back to Sardinia it's like okay well
how are they getting C15 level so high
there's a whole lot of Hope here right
so it's like how are they doing it so
when we looked at Sardinia and just
basically all the papers tons of papers
published on Sardinia we found that they
just like you had mentioned they have
they first all the food that they eat
comes from what they make so it's local
and they're they have primarily replaced
meat with dairy so meat is only eaten
maybe once a week on Sundays and special
occasions otherwise they've basically
repeat replaced where most people eat
meat with dairy the dairy which is can
be up to 25% of the caloric intake is
dairy I'm not recommending that for just
in general but remarkable right
so where we hit The Sweet Spot is the
type of dairy they're eating so they are
goat and sheep herders as you had
mentioned they it is in a mountainous uh
region of the island of sardini
and the goats and the Sheep are grazing
on mountainous grass now other Studies
have shown that not only does do
grass-fed animals produce milk with
higher c-15 so if you take a cow and you
feed it grass just any type of grass it
will have twice as much C15 in its milk
than a cow that is fed 100% corn so
there's already right a huge
differentiate in there so we know that
eating the grass there are other studies
show that not only is eating grass going
to help but the higher the altitude the
grass the higher the C15 in their milk
so now you've got gr mountainous grass
eating local ghosts and sheep um
creating this um milk that is very high
in C15 so like double the amount of C15
as other animals and we know why right
it's they're eating mountainous grass
closer to the Sun perhaps maybe like
something happening in the grass there
where very well could be I mean the same
thing was repeated in the Alps so they
went there was a separate study done in
the Alps and they showed that uh the Alp
grass um had led to higher C15 in milk
and cows that were gracing in Alpine
grass versus others so you know this is
actionable right so this is something
that can be done indust you not
necessarily industrywide but there shows
that there's hope for us to be able to
get c-15 hire c-15 back into our Dairy
so when we look at the cheeses they eat
um they eat peino cheese which is a hard
sheep cheese and peoni cheese has C15
levels that are twice as much as even
cow's butter which was previously seen
as like the high C15 one so peino cheese
great um they have another type of
cheese that they eat that's like a soft
goat cheese that they age for 30 days
and what studies showed is that the C15
in those or the fatty acids in that
cheese are actually free fatty acids so
it there's over that aging period the
fatty acids go from these complex lipids
to these like easy and bioavailable free
fatty acids so now not only do you have
C higher c-15 it's now more bioavailable
because it's a free fatty acid so then
you add those together and it's like
that's how they're getting high
C15 and associated with um lower heart
disease so people in Sardinia live
longer because they're less likely to
die of heart disease which is why men
are living longer um and now numerous
studies showing that people with higher
15 especially between 04 to 0.55% lower
risk of eing heart disease so you know
everything starts coming together with
regard to Sardinia is giving us a lot of
hope that can we repeat that you know
model globally it's I know there is some
literature over a decade ago too on like
high altitude uh cows in Switzerland and
the cheese having higher levels of
conjugated lenic acid as well which is
again another you know really important
compound
when you look at uh so just to clarify
like C15 this is an essential fat that
body can't create it so it has to come
from the diet that's right yeah so it's
you know because I know obviously
there's there's certain compounds in the
body where well maybe we could dig a
little deeper and understand why we're
not producing enough of it yada out of
it this isn't the case this is purely
something we would get from the diet
yeah exactly and so you know there there
is our body has some production of um
C15 uh some of it can come from when we
eat fiber uh that fiber uh contains
inulin inulin feeds microbes in our gut
and those microbes can use inulin to
make c-15 so there's some production
it's still coming from the diet because
we're eating the fiber um and that you
know that can create some C15 the big
thing with regard to the essential fatty
acid you know that you're talking about
um Thomas is that do we make enough C15
to be able to
support the you know long-term health
and what it appears to be is that we can
get enough
our bodies can do enough to get to or
whatever we're eating whatever it is
that we're eating gets a successful to
this 0 2% but we need to get above that
and it's not that much more it's just
like we just have to get out of this
danger zone and get into the safe zone
of having ourselves stable enough it it
appears to be very clear that we have to
have some amount of C15 in our diet to
be able to achieve those levels and
hence the essentiality yeah I mean it's
it's not it's not realistic I mean as
much as I would love to pack up and move
to Sardinia like I probably wouldn't
complain like it's not realistic for us
to get 25% of our our calories from you
know from dairy that's just unrealistic
so it's you know when you look at okay
sure these populations they've got it
going on like I mean I know from the
case of Sardinia U like happiness scores
with men are significantly higher I know
like they the men have I can't remember
what they it's a specific term for it
but the men have more DED at like social
time whereas like in other regions men
are a little bit more isolated also
focused on work and things like that
there's a like a lifestyle component
that allows men a little bit more of
this like social aspect that is seems
higher than in other regions so there's
a happiness score with the men um so
that might add into that I mean the
whole lifestyle with Sardinia is amazing
obviously the like the mineral profile
they get from the shellfish it's you you
talk about death by a Thousand Cuts in
this case it's like the other right it's
like it's like okay they've just got
it's in isolation so many things going
for them and then you look at okay well
if we even tried to engineer that into
our lives in the United States first of
all I don't think that it would be the
same equation with bow Vine Milk you
know so you go to the US and it's like I
mean I I don't know the statistic if I
had to guess it's probably more than 98%
is consumption of Bine milk versus goat
milk most people I talked to don't even
like goat I love goat milk but goat milk
and goes most people just want so it's
like okay already you're at a lower
amount of C15 to begin with not to
mention I'm going to get in trouble for
saying this but there's probably less
pasteurization and stuff occurring like
in Sardinia like it's probably more raw
milk consumption and you know that's
only allowed in eight states in the
United States to even have raw milk in
the first place so who knows I you might
know I mean if if pasteurization breaks
down some of the C15 I don't know it's
the bottom line is like it's probably
unrealistic to get adequate amounts of
C15 you know from from the diet uh you
know via dairy in the States yeah I I
think you know Thomas it's it's a good
point like we used to I mean because it
seems like we used to get enough and
because the point is you know gosh over
what's been happening this accelerated
aging the increase in type 2 diabetes
and heart disease and you know um fatty
liver disease showing up something is
worse now than it was before like prior
1990 and you know
1990s is when 1977 is when Congress
released recommendations saying hey um
saturated all saturated fats are bad for
you specifically stop drinking whole fat
milk and stop eating butter and that
will save your hearts um that ended up
being partly true and partly devastating
right so in that whole dairy fat it
contains that from from cows has one
less one or less than 1% C15 of all the
fats it has more than 40%
pro-inflammatory saturated fats so C15
you know even in dairy fat especially
the ones that we're talking about you
know not in Sardinia are kind of having
to go an uphill battle with regard to
C15 be able to do its good job battling
against you know much higher levels of
these pro-inflammatory fats other
Studies have shown that the higher fat
we eat um with C15 in it the less likely
our c-15 levels will actually go down
and that is because when we go to absorb
all those fats at the same time in the
food c-15 loses and so we're have a
higher tendency to absorb these
pro-inflammatory fats versus C15 so
there are a lot of things that kind of
put Dairy at odds There's Hope because
it's worse than it was so then the
question is can we get to Sardinian
level you know which is which is your
challenge right personally your
challenge our challenge globally
challenge accepted all right good deal
go have some peina um so uh so you know
can we get to Sardinia even if we were
at 1950s you know us probably not
because of all these other challenges
the last part to put in with regard to
Dairy is that there was a group of a
panelists and so these were experts in
dairy fat and in nutrition uh they met
in um Europe back in 2017 and they asked
this question which is okay whole dairy
fat or individual ingredients within uh
within dairy fat is there really a
difference because we're always taught
that whole food is better and in most
cases this is absolutely true what they
concluded is that dairy fat because
they're over 400 fatty acids there just
a lot happening Dairy F we were talking
about how much variation there can be in
dairy fat that thousands of studies
being done on dairy fat conclude that
you it does not reliably improve our
metabolic heart and Liver Health there
are studies that show that it does there
are just as many studies showing that it
doesn't so their conclusion was you
can't just eat more dairy fat um to get
these individual nutrients to support
your metabolic heart and Liver Health
what they did conclude is that
individual nutrients within dairy fat
can have a beneficial effect but they
have to be taken out of that milu what
they call the Matrix in order to be able
to have their fact and this sounds like
a spin but it's you know this is a group
that has no bias um and what they their
conclusion is they're just times in
which you know we can use nature to find
a nutrient that can really shine when it
doesn't need to compete especially with
these changes in agriculture um that we
have less and less control over so that
was a really long Answer to No but it's
I mean it's and part of me thinks too is
like okay the sardinians also eat in a
pretty like consistent deficit all the
time right so it's like you can't deny
the literature that
supports heavy saturated fat consumption
being problematic specifically in a
surplus right like that's like I haven't
seen a lot of data to support like I
just don't think the cohort really
exists to be like hey like let's look at
people that consume high amounts of
saturated fat but they're also in a
deficit like that pretty much doesn't
exist in America like if you're eating
saturated fat you are probably in the
category like high amounts of saturated
fat you're you're not doing a carore
diet you're not doing this you're
probably in the category of people that
are getting saturated fat from fried
foods and things so it's just the cohort
doesn't exist we can't look at that you
know so it's like you look at Sardinia
it's like sure their saturated fat
consumption as a percentage of their
diet is probably astronomically high but
they're also living in a probably
consistent 10 to 15% deficit and they're
probably having all these other factors
that are positively compounding that
right so it's the saturated fat the
there's less it's granted a little bit
of amnesty because it's overridden by
all this other positive stuff you apply
that to the us if you were to tell
people in the US it's almost dangerous
it would almost be irresponsible to say
hey United States as a whole people that
don't have nutrition education you need
to eat more cheese is the first thing
they're going to probably do is go to
does Arby have cheese I don't know but
like you know they're going to go and
ask for more queso right like it's it's
different like it's it's I understand
the issue there I know that you know C15
just just like other uh you know some
other things like you can get in
supplement form you know you you guys do
a great job with fatty 15 and C15 there
and I'll link out to that down below but
I mean it sounds like that's I mean
really the way to go for specific C15
like in isolation yeah I think you know
there are multiple things we need to do
right and SOC now that there is really
is a true nutritional deficiency
syndrome we need to fix it so if you
know you find out that scurvy is caused
by vitamin C icy you don't come up with
other ways other than like let's start
with getting vitamin C C back and so
same thing here and so there are
multiple ways to be able to bring c-15
back into our lives you know Eric uh you
know my Navy physician husband and I
this was all discovered when we you were
working at the Navy you know as you know
myself as a civil servant and um you
know Eric as active duty
so um as we were doing the science and
the studies what became apparent to us
is that and working in cooperation with
the Navy is that we had an opportunity
for a pure C15 ingredient to be able to
be more potent bioavailable vegan
friendly to help with this problem so it
wasn't to create a market right it's
like unfortunately the Dolphins were
showing there's a need and you know the
military way is that if you have a
problem research is invested on how to
fix it which is why all of this work how
about
that so was like I know this sounds
crazy but it's like office enval
research funded this work and it was
specifically to say hey we've identified
the syndrome in Dolphins here's the
money to do the research to figure out
what the problem is and to fix it and
you have X number of years it is not
like you spend your career working on
little intricacies of it and Publishing
papers it is a it's a problem that you
solve go fix it and so which we did and
we did and you know for the Dolphins we
did in about four years time because
that's what you do with the military so
this really was this whole thing was
born from saying hey we see a problem it
started with navy Dolphins right and
then now that extended to now global
health and so it's a problem and so one
way to fix it one part of the solution
is to have a pure ingredient that
basically helps take over or puts aside
these other barriers uh you know having
to compete with pro-inflammatory
saturated fats Let It Be vegan friendly
have it well controlled so that is more
than
99.8% pure at the exact amounts we need
we now know that the average person
needs between 100 to two milligrams at
least of pure B available c-15 per day
um so that is what the dose of fatty 15
was so this was all driven by a decade
of science before we even thought of
bringing you know this ingredient to the
market so we do feel strongly that this
ingredient will play an important role
with regard to for not just as a
supplement but fortifying Foods how do
we increase accessibility to c-15
globally because this problem is not
just in the US you know it's everywhere
mostly in developed um countries because
we've created this problem um and on top
of that okay what can we learn from
Sardinia okay so maybe um know cows we
should be feeding them more grass let's
put pressure on the industry to be able
to report for dairy products report how
much C15 is in your product so that when
consumers go to the store they can look
at the different dairy products and say
if I'm going to choose butter a or
butter B I want to choose the one that
has higher C15 in it so I think there
are ways um we can move forward another
one is with kids you know pediatricians
in the 1990s really made this movement
of saying um we went from
all Americans should avoid eating whole
fat drinking whole fat Dairy and eating
butter and that was 1977 through 1990
then around 1990 1991 the Pediatric
Community came in um again all with good
intentions but they then said okay young
children infants um and toddlers should
not get whole fat milk and it was pretty
bold um at the time so we went from
before 1990 a 12-month-old um child um
90% of them will have had whole fat milk
by the time they're one um today it's
less than 10% of children have been
exposed to whole fat cow's milk so it's
been a dramatic so now we're talking
about the youngest of young not getting
adequate c-15 levels even from Mom's
milk because if Mom is C c-15 deficient
she has less c-15 in her milkk so we're
talking about deficiencies that are
starting at Birth which is why we're
seeing this translating to these are now
um people turning 30 years old yeah I
mean we have massive like cell
differentiation that's occurring at that
age and it's like who knows even
epigenetically who knows like what
that's doing for them how it's setting
them up for or not setting them up for
success as they get older right it's
like when such a pivotal time yeah
there's a study that just came out in
fact it's a pre-print right now that
show in which um it's a big study done
in France and they follow um moms from
pregnancy and then um through baby being
born through the children developing and
right now they have the kids up to I
think about 11 years old and some of the
oldest ones in the cohort and what the
pre-print shows is that moms who had
less C15 in their red blood cell
membrane during pregnancy and in the in
their milk um resulted in kids uh if
they had lower C15 the kids don't
perform as well as 2year olds threeyear
olds and five and six year olds
cognitively um so it's just you know
like you're saying what does this mean
from a developmental level and so that
it's not like oh therefore all infants
should get fatty 15 right this is like
how about why don't we start by getting
whole fat milk safely you know back into
um you know into our youngest of young
and you know things like um infant
formulas have no c-15 in them no and so
separate papers you know made a call to
action saying we should be putting C15
fortifying C15 in infant formulas
because it's becoming clear and clear
this is an essential nutrient we we need
so there's a lot of things um to be done
we think you know fat5 and supplements
part of the solution but we're really
working with the whole Community Global
Community to fix you know a big problem
the upside is there's so much hope
because there's a solution yeah I there
I and I have mixed feelings on like
fortification of foods but at the same
time it's like this is something where I
mean is that in your crosshairs at all
like just being like okay we've got like
good you know dairy product like okay we
fortify with vitamin D because we saw
that as an issue yeah like is there is
it in your crosshairs to see like hey
like we can or where's your stance on
fortification with C15 yeah I think in
this case it's you know c-15s it's it's
the next natural biggest impact step so
you know supplements are great great
because people could choose and we have
super Savvy you customers who do the
Deep dive on the science who listen to
you know your podcast and you know are
ready to learn are diving in they have a
lot of knowledge they come back with
really smart questions which we greatly
appreciate um and they're ready to come
in and be like the early adopters right
and um and so supplementation is a great
place to start where really the global
impact can be is going to be
fortification of of foods and the nice
thing about C15 as an ingredient is it's
really stable so a lot of times we think
about fats and fatty acids like omega-3
and Omega 6es those are oils those are
just tough T to like they get attacked
by oxygen so they go bad really fast we
happen to be gifted with c-15 in which
its whole role is a stabilizer so it
stabilizes our cells a big part of that
is because it's not an oil right it's a
it's a um a stable powder at room
temperature so that means it doesn't go
bad so this means it's just Prime to be
able to fortify Foods in anywhere in the
world and be a stable way to you know
get this nutrient you know back into
people's lives affordably uh so that's
really our next stop um is how do we use
this as part of uh you know a broad
solution is there a way for people to um
like see where their c-15 levels are at
or I mean is that is that even possible
now or is it really just right now it
takes pretty extensive work um so so it
used to be where you needed to get a
fatty acid panel um which isn't the end
of the world but it's not like you any
of us go to our doctors and they're like
oh here your here's your fatty acid pan
then uh I don't know if you not
everyone's uh you know I don't know if
anyone saw the South Park episode on the
uh it was the OIC episode but like n
quote the song The navigating the
American Healthcare System song that
Butters was singing I just it's amazing
and it just just so I'm just saying like
Okay here here's me going to go get an
essential fatty acid pan
uh it's going to take me two weeks of
going to four different doctors and
calling yeah so yeah fits right along
Butters and the fact that's butter is
kind of Butters Butters um so uh so now
uh so there are a lot of functional um
Physicians and Healthcare practitioners
that have been using a fatty acid panel
for maybe at least the F last five years
that has included C15 so we've talked to
a lot of as we've been working with a
lot of functional medicine practitioners
they're like my gosh wait we've actually
been collecting c-15 we didn't know
whether we should care about and as
they're going back Thomas they're like
writing us back and they're like oh my
gosh we see like 12% of the people that
you know of our you know patients that
we've been looking at over the past 5
years 12% are unquestionable like we're
talking like 0.002% or 04 versus 0.2
right and uh and then another 12 to 14%
being in this like less than 0.2 to you
know 0.1% and so they're like no this is
real we're like well yeah you know it's
definitely real so the test has been
available um what we're now doing is
we've um partnered with gova Diagnostics
to be able to have an atome spot test um
for c-15 so that people can get their
c-15 levels measured um uh via uh goova
so this is theirs um independent but as
we were um making these discoveries
obviously the next next natural question
is well that's great but how do I know
what my C15 levels are so um now there's
a way to be able to do that i''d be
curious to test mine now I was just in
Europe for a month and I think I like
pretty much only the only thing I ate
was like drinking like six lattes a day
and eating cheese and the occasional
Pudo and that was like my diet for a
month so yeah I think you're probably be
in that
3.44 not quite Sardinian but get close
do you actually see is it something that
builds up over time or uh you see a
pretty rapid increase upon like
increasing not only diet but also
supplementation form of it yeah so in
general it takes I mean to to safely get
to understand where you're at the nice
thing that uh this test measures it it
actually measures the amount of C15 in
your red blood cell membranes so other
tests might measure serum and plasma
which kind of gets to what you're you
might have the spike that goes up and
down it's less reliable like when you
talk about glucose versus hba1c this
would be your the red blood cell
membrane is like your hb1c so it's a
more stable measurement and it's
stabilizing your cell membranes so to
actually get that measurement of your
cell membranes is the most directly
important um so it measures um those
levels um that you're then able to um
work off of from there interesting well
I will most importantly link out to the
study down because I I do know that and
I hope the viewers know that you know
the more eyeballs that get on a study
the better like it's algorithmic just
like everything else in the world now so
you know get eyeballs on the study
because this is one of those things
where it's like people say why isn't
this front page news it's like we focus
on so many other things and this is this
is clear legit science this is not
Fringe Weird Science cherry-picking
connect the dots BS like this is real
stuff and it needs the eyeballs on it
and that's why I brought you here and I
know yes you have a supplement company
with C15 and I'll link out to that down
below but that was not the purpose of
this video the purpose is like let's get
eyeballs on this study because people
legitimately need to know this yeah
thanks Thomas I mean we call oursel a
team of nerdy do Cutters and our whole
purpose is really to help improve Global
Health that was our job as a military
family it's our job you know with this
company so thank you for helping to get
the word out yeah awesome thank you for
coming and thanks Eric for the workout
this
morning all right so uh as always keep
it locked in the channel I'll link out
to everything down below and thank you
great thank you
Посмотреть больше похожих видео
Insulin Resistance Explained! What Is Insulin Resistance & How It Leads To Type II Diabetes?
Why Fructose causes insulin resistance | Insulin Resistance | Jason Fung
The SURPRISING Way To Reverse A FATTY LIVER | Dr. Mark Hyman
MAFLD
New Vitamin D Guidelines by Endocrine Society- what they imply for Indians
The study of organelles
5.0 / 5 (0 votes)