How to Determine Optimal Ketone Levels for Ketogenic Therapy with Dr. Bret Scher

Summary

In this video, Dr. Bret Scher from Metabolic Mind discusses the significance of ketone levels for individuals on a ketogenic diet for various health conditions, including psychiatric disorders, type 2 diabetes, and seizures. He outlines general target ranges for ketone levels depending on health goals, emphasizing the importance of individual response and the need for medical supervision. The video also addresses safety concerns regarding high ketone levels and the potential for ketoacidosis, advocating for a flexible approach to finding the optimal ketone level for each person.

Takeaways

• 🍽 The ketogenic diet is used for treating conditions like psychiatric disorders, type 2 diabetes, PCOS, dementia, and other metabolic conditions.
• 📏 Ketone levels can be measured to gauge the effectiveness of the ketogenic diet, which is unique compared to other diets.
• 🚫 The video is for informational purposes only and not a substitute for medical advice. Consult a healthcare provider before making lifestyle changes.
• 🔍 There is no one-size-fits-all ketone level; individual responses to ketosis can vary greatly.
• 📉 For weight loss, ketone levels may not be as critical as adhering to the prescribed diet.
• 💉 Aim for ketone levels between 0.5 and 1.5 mmol/L for diabetes remission.
• 🌡 Ketone levels between 2.5 and 4 are typically targeted for seizure control.
• 🧠 For mental illnesses, ketone levels between 1.5 and 3, or slightly higher, may be beneficial.
• 📌 Ketone levels can be measured using blood tests for beta hydroxybutyrate or breath meters for acetone.
• 🚫 Urine strips are not recommended for quantifying ketone levels but can indicate if someone is in ketosis.
• ⚠️ High ketone levels above 3.8 mmol/L are traditionally considered ketoacidosis, but this may not apply to those on a ketogenic diet.

Q & A

What is the primary purpose of a ketogenic diet?

The primary purpose of a ketogenic diet is to induce a metabolic state called ketosis, where the body switches from burning glucose to burning fat as the primary fuel source, producing ketones that the brain can use for energy.

Why is measuring ketone levels beneficial on a ketogenic diet?

Measuring ketone levels is beneficial because it allows individuals to quantify their response to the diet, ensuring that their body is in ketosis and producing the necessary ketones for the intended health benefits.

What is the role of Metabolic Mind in the context of this script?

Metabolic Mind is a non-profit initiative of Baszucki Group that aims to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health, as discussed in the script.

Why is it important to consult a healthcare provider before starting a ketogenic diet?

It is important to consult a healthcare provider before starting a ketogenic diet because the diet can have potentially dangerous effects if done without proper supervision, and individual responses to ketosis can vary significantly.

What is the general range for ketone levels in nutritional ketosis?

Nutritional ketosis generally starts at a ketone level of 0.5 millimoles per liter, but the target level can vary depending on individual health goals and responses.

What is the suggested ketone level range for weight loss on a ketogenic diet?

For weight loss, adhering to the prescribed diet is more important than a specific ketone level, as long as the individual is in ketosis.

What ketone level range is recommended for remission of type 2 diabetes on a ketogenic diet?

For diabetes remission, it is suggested that ketone levels be maintained between 0.5 and 1.5 millimoles per liter for potentially better results.

What is the target ketone level range for seizure control in children?

The target ketone level range for seizure control in children is usually between 2.5 and 4 millimoles per liter, as reflected in evidence-based guidelines.

What is the suggested ketone level range for treating serious mental illnesses?

For serious mental illnesses, the suggested ketone level range is probably between 1.5 and 3 millimoles per liter, or possibly a little bit higher.

Why is it advised not to focus too much on a specific ketone level number?

It is advised not to focus too much on a specific ketone level number because individual responses to ketosis can vary, and the goal should be flexible, adjusting based on the individual's progress and health outcomes.

What is considered a potentially dangerous ketone level, and how should it be treated?

Ketone levels above 3.8 millimoles per liter are generally considered potentially dangerous and indicative of ketoacidosis. However, for those on a ketogenic diet, different criteria may apply. Any elevated ketone level associated with symptoms like nausea, vomiting, dehydration, or mental confusion should be treated as a potential medical emergency.