History of Pharmacy

Dr. Albert Chester II
6 Dec 201907:41

Summary

TLDRThis script offers a comprehensive history of pharmacy, from ancient practices in Egypt and Greece to modern advancements in the United States. It covers key figures like Imhotep and Hippocrates, significant publications like the United States Pharmacopoeia, and important legislation such as the Food, Drug, and Cosmetic Act. The script also discusses various pharmacy settings and the evolution of drug regulations, emphasizing the profession's growth and impact on healthcare.

Takeaways

  • πŸ’Š **Pharmacy Defined**: Pharmacy is the practice of preparing, preserving, compounding, and dispensing medical drugs.
  • πŸ§ͺ **Apothecary**: An apothecary is a druggist or pharmacist, historically known as a drugstore of pharmacy.
  • πŸ‘¨β€βš•οΈ **Pharmacy Technician**: A healthcare provider who performs pharmacy-related functions under the supervision of a licensed pharmacist.
  • πŸ“š **Pharmacology**: The study of drugs, including their properties, uses, applications, and effects.
  • 🌿 **Ancient Beginnings**: Pharmacy's origins trace back to 3000 BC with Imhotep in ancient Egypt, establishing early medical practices.
  • πŸ“œ **Papyrus Ebers**: A scroll from 1500 BC listed over 800 prescriptions, showcasing early drug formulations.
  • πŸ›οΈ **Hippocrates**: A Greek physician in 400 BC who established early medical practices and the Hippocratic oath.
  • πŸ“– **US Pharmacopoeia**: Founded in 1820, it set standards for drug manufacturing in the United States.
  • 🏫 **Philadelphia College of Pharmacy**: Established in 1821, it published the American Journal of Pharmacy in 1825.
  • πŸ”¬ **American Pharmaceutical Association**: Founded in 1852, now known as the American Pharmacists Association (APhA), it's a leading professional body for pharmacists.
  • πŸ“ˆ **Pharmacy Laws**: By 1878, nine states had pharmacy laws, leading to the establishment of Boards of Pharmacy to regulate pharmacy practice.
  • πŸ“š **Remington's Practice of Pharmacy**: First published in 1885, it became a standard text and is still widely used.
  • πŸ’‰ **Milestone Drugs**: Quinine, cocaine, digitalis, penicillin, insulin, and salicylic acid are significant discoveries in medicine.
  • 🚫 **Drug Regulations**: The Food and Drug Act of 1906 prohibited interstate commerce of adulterated food and drugs.
  • πŸ₯ **Health Insurance Portability and Accountability Act (HIPAA)**: Enacted in 1996, it provides regulations to protect patient privacy.
  • 🏒 **Types of Pharmacy**: Community, hospital, clinical, ambulatory care, compounding, internet, mail-order, veterinary, nuclear, military, pharmacy informatics, and specialty pharmacy are various settings where pharmacy practice occurs.

Q & A

  • What is the definition of pharmacy?

    -Pharmacy is the art, practice, or profession of preparing, preserving, compounding, and dispensing medical drugs.

  • What is the role of an apothecary?

    -An apothecary is a druggist or pharmacist who was historically responsible for preparing and dispensing medicinal drugs.

  • What is the job of a pharmacy technician?

    -A pharmacy technician is a healthcare provider who performs pharmacy-related functions generally under the direct supervision of a licensed pharmacist.

  • What is pharmacology?

    -Pharmacology is the study of drugs, their properties, uses, application, and effects.

  • Who was the first to establish official medical healing practices?

    -Imhotep, the god of medicine and a priest and physician to ancient Egypt, was the first to establish official medical healing practices around 3000 BC.

  • What is significant about the Papyrus Ebers?

    -The Papyrus Ebers, written around 1500 BC, is significant because it listed over 800 prescriptions using 700 verbal remedies.

  • Who established practices of treating patients and the Hippocratic oath?

    -Hippocrates, a Greek physician around 400 BC, established practices of treating patients and also established physician conduct which included the Hippocratic oath.

  • When was the United States Pharmacopoeia founded and what was its purpose?

    -The United States Pharmacopoeia was founded in 1820 with the purpose of creating standards for manufacturing drugs.

  • What is the American Pharmacists Association (APHA) and when was it founded?

    -The American Pharmacists Association (APHA), originally known as the American Pharmaceutical Association, was founded in 1852 and is the first established and largest professional association of pharmacists in the United States.

  • What is the significance of the Food and Drug Act of 1906?

    -The Food and Drug Act of 1906 prohibited interstate commerce of adulterated or misbranded food, drinks, and drugs, and required government pre-approval of drugs.

  • What does the Controlled Substances Act (CSA) do?

    -The Controlled Substances Act (CSA) classifies drugs that may be easily abused and restricts their distribution, enforced by the Drug Enforcement Administration (DEA).

  • What are the different types of pharmacy settings mentioned in the script?

    -The script mentions community pharmacy, hospital pharmacy, clinical pharmacy, ambulatory care pharmacy, compounding pharmacy, internet pharmacy, mail-order pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, and specialty pharmacy as different types of pharmacy settings.

Outlines

00:00

πŸ’Š History and Development of Pharmacy

The first paragraph provides a comprehensive overview of the history and development of pharmacy. It starts with defining pharmacy as the practice of preparing and dispensing medical drugs and introduces key terms such as apothecary, pharmacist, and pharmacy technician. It then delves into the historical roots of pharmacy, mentioning Imhotep, the god of medicine in ancient Egypt, and the papyrus Ebers, which listed over 800 prescriptions. The contributions of Hippocrates, who established early medical practices and the Hippocratic oath, are also highlighted. The paragraph then shifts to the history of pharmacy in the United States, mentioning the founding of the United States Pharmacopoeia in 1820, the Philadelphia College of Pharmacy in 1821, and the American Journal of Pharmacy in 1825. It discusses the establishment of the American Pharmaceutical Association in 1852 and the introduction of the pharmaceutical board by John Maish in 1868. The paragraph also covers significant publications like 'The Dispensatory of the United States of America' and 'Remington's Practice of Pharmacy'. It concludes with a discussion on the development of various drugs, such as quinine, cocaine, digitalis, penicillin, insulin, and salicylic acid, and the evolution of drug regulations and laws, including the Food and Drug Act of 1906, the Food, Drug, and Cosmetic Act of 1938, the Durham Humphrey Amendment of 1951, the Kefauver Harris Amendments of 1962, and the Controlled Substances Act of 1970.

05:01

πŸ“š Drug Scheduling and Pharmacy Practice

The second paragraph focuses on drug scheduling and the different types of pharmacy settings. It begins by defining Schedule 1 drugs as those with high potential for abuse and no accepted medical use, providing examples such as heroin, LSD, and marijuana. It then describes Schedule 2 drugs, which have a high potential for abuse but are accepted for medical use in certain circumstances, with examples like Vicodin, cocaine, and methamphetamine. The paragraph continues with Schedule 3 drugs, which have a moderate to low potential for abuse, and Schedule 4 drugs, which are considered to have a low potential for abuse and dependence. Schedule 5 drugs are also mentioned, which are used for anti-diarrheal, anti-tussive, and analgesic purposes. The paragraph then discusses the Omnibus Budget Reconciliation Act of 1990 (OBRA), which required pharmacists to offer counseling to Medicaid patients, and the Health Insurance Portability and Accountability Act of 1996 (HIPAA), which provided regulations to protect patient privacy. Finally, it outlines various pharmacy settings such as community pharmacy, hospital pharmacy, clinical pharmacy, ambulatory care pharmacy, compounding pharmacy, internet pharmacy, mail-order pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, and pharmacy informatics.

Mindmap

Keywords

πŸ’‘Pharmacy

Pharmacy refers to the art, practice, or profession of preparing, preserving, compounding, and dispensing medical drugs. It is central to the video's theme as it sets the stage for discussing the historical development and modern practices within the field. The script mentions various aspects of pharmacy, such as the role of pharmacists and pharmacy technicians, and the evolution of pharmacy practices over time.

πŸ’‘Apothecary

An apothecary is a term that historically referred to a druggist or pharmacist who prepared and sold medicinal drugs. This keyword is significant as it connects to the video's historical narrative, illustrating the roots of modern pharmacy. The script mentions Imhotep, who is considered one of the earliest figures associated with medical healing practices, which could be seen as the precursor to the apothecary profession.

πŸ’‘Pharmacology

Pharmacology is the study of drugs, including their properties, uses, application, and effects. This field is integral to the video's exploration of how drugs are understood and utilized within the medical context. The script discusses various drugs and their historical significance, such as quinine for malaria and digitalis for heart disease, which are relevant to pharmacology.

πŸ’‘United States Pharmacopoeia

The United States Pharmacopoeia (USP) is mentioned in the script as being founded in 1820 to create standards for manufacturing drugs. This keyword is crucial as it represents a milestone in the regulation and standardization of pharmaceuticals in the United States, which is a key aspect of the video's discussion on the evolution of pharmacy practices.

πŸ’‘American Pharmaceutical Association (APA)

The APA, now known as the American Pharmacists Association (APhA), is highlighted in the script as being founded in 1852. This keyword is important as it signifies the establishment of a professional association for pharmacists, which is a significant step in the professionalization and advancement of the pharmacy field.

πŸ’‘Registered Pharmacist

A registered pharmacist is a legally recognized and licensed professional who practices pharmacy. The term is mentioned in the context of John Maish's introduction of pharmaceutical boards and the establishment of the term 'registered pharmacist'. This keyword is relevant to the video's theme as it discusses the formalization and regulation of the pharmacy profession.

πŸ’‘Dispensing

Dispensing refers to the process of distributing pharmaceuticals to patients. It is a key activity within the pharmacy profession and is mentioned in the script in relation to the roles of pharmacy technicians and pharmacists. The video's discussion on dispensing underscores the importance of accurate and safe medication distribution.

πŸ’‘Food and Drug Act of 1906

The Food and Drug Act of 1906 is a historical legislation mentioned in the script that prohibited interstate commerce of adulterated or misbranded food, drinks, and drugs. This keyword is significant as it marks the beginning of federal drug regulation in the United States, which is a critical part of the video's narrative on drug safety and regulation.

πŸ’‘Controlled Substances Act (CSA)

The CSA, mentioned in the script, classifies drugs that may be easily abused and restricts their distribution. This keyword is important as it relates to the video's discussion on drug regulation and the efforts to control theζ΅ι€š of potentially dangerous substances. The CSA is enforced by the DEA and includes a schedule system for drugs, which is detailed in the script.

πŸ’‘Schedule 1 Drugs

Schedule 1 drugs are defined as having no currently accepted medical use and a high potential for abuse. This term is used in the script to illustrate the classification system under the CSA. The mention of Schedule 1 drugs in the video helps to explain the severity of drug regulation and the categorization of substances based on their potential for abuse.

πŸ’‘Pharmacy Settings

Pharmacy settings refer to the various environments where pharmacy practices occur, such as community, hospital, and clinical pharmacies. This keyword is relevant to the video's exploration of the diverse applications of pharmacy in different healthcare contexts. The script provides examples of different settings, showcasing the breadth of the pharmacy profession.

Highlights

Pharmacy is the practice of preparing, preserving, compounding, and dispensing medical drugs.

An apothecary or pharmacist is a druggist or professional in the field of pharmacy.

A pharmacy technician is a healthcare provider working under the supervision of a licensed pharmacist.

Pharmacology is the study of drugs, their properties, uses, application, and effects.

Imhotep in 3000 BC was the first to establish official medical healing practices.

The Papyrus Ebers, from 1500 BC, listed over 800 prescriptions using 700 verbal remedies.

Hippocrates in 400 BC established practices of treating patients and the Hippocratic oath.

The United States Pharmacopoeia was founded in 1820 to create standards for drug manufacturing.

Philadelphia College of Pharmacy was founded in 1821.

The American Journal of Pharmacy was the first periodical in the United States devoted to pharmacy, published in 1825.

William Procter Jr. was a key figure in the establishment of the American Pharmaceutical Association in 1852.

John Maish introduced the idea of pharmaceutical boards appointed by state governors in 1868.

By 1878, nine states had adopted pharmacy laws licensing pharmacists.

Joseph P. Remington published 'The Practice of Pharmacy' in 1885, which became a standard text.

Quinine was the first drug to successfully treat malaria.

Cocaine was the first effective local anesthetic.

Digitalis, from the foxglove plant, has been widely used in treating heart disease.

Penicillin was the first antibiotic and a great discovery in medicine in the 20th century.

Insulin is the hormone that lowers blood sugar used in the treatment of diabetes.

The Food and Drug Act of 1906 prohibited interstate commerce of adulterated or misbranded food, drinks, and drugs.

The 1938 Food, Drug, and Cosmetic Act required new drugs to be shown as safe before marketing.

The Durham Humphrey Amendment of 1951 defined drugs requiring a prescription.

The 1962 Kefauver Harris amendments required proof of safety and effectiveness before drug marketing.

The 1970 Poison Prevention Packaging Act required childproof packaging on controlled and prescription drugs.

The Controlled Substances Act of 1970 classifies drugs based on abuse potential and restricts their distribution.

Schedule 1 drugs are defined as having no accepted medical use and a high potential for abuse.

Schedule 2 drugs are considered dangerous with severe psychological or physical dependence.

Schedule 3 drugs have a moderate to low potential for physical and psychological dependence.

Schedule 4 drugs are defined as having a low potential for abuse and low risk of dependence.

Schedule 5 drugs consist of preparations with limited quantities of certain narcotics for anti-diarrheal, anti-tussive, and analgesic purposes.

The Omnibus Budget Reconciliation Act of 1990 required pharmacists to offer counseling to Medicaid patients.

The Health Insurance Portability and Accountability Act of 1996 provided regulations to protect patient privacy.

Transcripts

play00:00

history of pharmacy pharmacy the art

play00:03

practice or profession of preparing

play00:05

preserving compounding and dispensing

play00:07

medical drugs apothecary a druggist or

play00:11

pharmacist a drugstore of pharmacy

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pharmacy technician sometimes known as

play00:16

pharmaceutical technician is a health

play00:19

care provider who performs pharmacy

play00:20

related functions generally working

play00:22

under the direct supervision of a

play00:24

licensed pharmacist pharmacology the

play00:28

study of drugs their properties uses

play00:30

application and effects world history of

play00:33

pharmacy in 3000 BC Imhotep the god of

play00:37

medicine a priest and physician to

play00:40

ancient Egypt Kemet was the first to

play00:43

establish official medical healing

play00:45

practices 1500 BC the papyrus evers a

play00:49

kinetic scroll listed over 800

play00:52

prescriptions using 700 verbal remedies

play00:55

400 BC Hippocrates a Greek physician

play00:59

established practices of treating

play01:01

patients his writings also established

play01:03

physician conduct which included the

play01:05

Hippocratic oath history of pharmacy in

play01:08

the United States founded in 1820 the

play01:11

United States pharmacopoeia created the

play01:13

standards for manufacturing drugs for

play01:15

more than a hundred years Philadelphia

play01:18

College of Pharmacy was founded in 1821

play01:20

in 1825 the first periodical in the

play01:23

United States devoted to the art and

play01:25

science of pharmacy the American Journal

play01:27

of Pharmacy was published by

play01:28

Philadelphia College of Pharmacy first

play01:31

published in 1833 Franklin Bach and

play01:34

George B would compiled a comprehensive

play01:36

commentary on drugs the dispensatory of

play01:39

the United States of America

play01:41

William Procter jr. William Procter jr.

play01:44

the father of American pharmacy with a

play01:46

professor at Philadelphia College of

play01:48

Pharmacy from 1846 to 1874 he and Daniel

play01:52

B Smith helped founded the American

play01:54

pharmaceutical Association in 1852 it is

play01:57

now called the American Pharmacists

play01:59

Association APHA the first established

play02:02

and largest professional association of

play02:04

pharmacists in the United States

play02:07

the more than 50,000 members of APHA

play02:10

include practicing pharmacist

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pharmaceutical scientist pharmacy

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students pharmacy technicians and others

play02:17

interested in advancing the profession

play02:18

john Maish in 1868 john mace introduced

play02:23

the idea of pharmaceutical board to be

play02:25

appointed by the governor of each state

play02:26

and established the term registered

play02:28

pharmacist by 1878 nine states had

play02:32

adopted pharmacy laws which licensed

play02:34

pharmacists every state now of course

play02:36

has a Board of Pharmacy which regulates

play02:38

the practice of pharmacy in 1885 Joseph

play02:41

P Remington published the practice of

play02:44

pharmacy which soon became established

play02:45

as the standard text in the field later

play02:47

renamed Remington the science and

play02:49

practice of pharmacy this comprehensive

play02:51

reference work remains widely used

play02:53

throughout the world quinine extracted

play02:57

from the Kinoshita tree bark the first

play02:59

drug to successfully treat malaria one

play03:01

of mankind's most deadly diseases

play03:03

cocaine the first effective local

play03:06

anesthetic digitalis the drug of the

play03:09

foxglove plant which has been widely

play03:11

used in treating heart disease

play03:13

penicillin the first antibiotic insulin

play03:17

the hormone that lowers blood sugar in

play03:19

the treatment of diabetes one of the

play03:21

great discoveries in medicine in the

play03:22

20th century salicylic acid a natural

play03:26

drug derived from the bark of the white

play03:27

willow tree used by ancient Greeks to

play03:30

relieve pain and the natural forerunner

play03:32

to the active ingredient in aspirin

play03:34

early drug regulations and laws Food and

play03:38

Drug Act of 1906 prohibited interstate

play03:40

commerce and adulterated or misbranded

play03:42

food drinks and drugs government

play03:44

pre-approval or drugs is required 1938

play03:47

Food Drug and Cosmetic FDC Act in

play03:51

response to the fatal poisoning of 107

play03:53

people primarily children B an untested

play03:56

sulfa Milla need concoction this

play03:58

comprehensive law requires new drugs be

play04:00

shown to be safe before marketing 1951

play04:03

Durham Humphrey amendment this law

play04:05

defines what drugs require a

play04:07

prescription by a licensed practitioner

play04:08

and requires them to include this legend

play04:11

on the label caution federal law

play04:13

prohibits dispensing without a

play04:14

prescription

play04:15

1962 Kepha V Harris amendments

play04:18

requires drug manufacturers to provide

play04:21

proof of both safety and effectiveness

play04:22

before marketing the drug 1970 poison

play04:26

prevention packaging Act requires

play04:28

childproof packaging on all controlled

play04:29

and most prescription drugs dispensed by

play04:32

pharmacies 1970 Controlled Substances

play04:35

Act CSA the CSA classifies drugs that

play04:39

may be easily abused and restricts their

play04:40

distribution it is enforced by the Drug

play04:42

Enforcement Administration DEA within

play04:44

the Justice Department schedule 1

play04:47

schedule 1 drugs substances or chemicals

play04:50

are defined as drugs with no currently

play04:52

accepted medical use and a high

play04:53

potential for abuse schedule on drugs

play04:55

are the most dangerous drugs of all the

play04:57

drug schedules with potentially severe

play04:59

psychological or physical dependence

play05:01

some examples of schedule on drugs are

play05:03

heroin lysergic acid diethylamide LSD

play05:07

marijuana or cannabis 3 4

play05:11

methylenedioxypyrovalerone for abuse

play05:22

with use potentially leading to severe

play05:24

psychological or physical dependence

play05:26

these drugs are also considered

play05:28

dangerous

play05:28

some examples of schedule 2 drugs are

play05:31

combination products with less than 15

play05:33

milligrams of hydrocodone per dosage

play05:35

unit vicodin cocaine methamphetamine

play05:38

methadone

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hydromorphone dilaudid meperidine

play05:43

Demerol oxycodone oxycontin fentanyl Dec

play05:48

cedron adderall and Ritalin Schedule

play05:51

three drugs substances or chemicals are

play05:53

defined as drugs with a moderate to low

play05:55

potential for physical and psychological

play05:56

dependence scheduled 3 drug abuse

play05:59

potential is less than schedule 1 and

play06:00

schedule 2 drugs but more than scheduled

play06:02

for some examples of schedule 3 drugs

play06:04

are products containing less than 90

play06:07

milligrams of codeine per dosage unit

play06:08

tylenol with codeine ketamine anabolic

play06:11

steroids testosterone schedule for drugs

play06:15

or substances or chemicals are defined

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as drugs with a low potential for abuse

play06:19

and low risk of dependence some examples

play06:21

of schedule for drugs are xanax

play06:23

soma valium ativan Cowan ambien

play06:27

tramadol schedule 5 drugs substances or

play06:31

chemicals are defined as drugs with low

play06:32

potential for abuse then scheduled for

play06:34

and consist of preparations containing

play06:36

limited quantities of certain narcotics

play06:38

schedule five drugs are generally used

play06:40

for anti diarrheal anti to civ and

play06:43

analgesic purposes some examples of

play06:45

schedule 5 drugs are cough preparations

play06:47

with less than 200 milligrams of codeine

play06:49

or per 100 milliliters robitussin AC

play06:52

lomotil motive and lyrica parapet : 1990

play06:59

I'm novice Budget Reconciliation act

play07:01

obra this Act required pharmacists to

play07:04

offer counseling to Medicaid patients

play07:06

regarding medications effectively

play07:07

putting the common practice into law

play07:10

1996 Health Insurance Portability and

play07:12

Accountability Act HIPAA provided broad

play07:15

and stringent regulations to protect

play07:17

patients privacy types of pharmacy

play07:19

settings community pharmacy hospital

play07:22

pharmacy clinical pharmacy ambulatory

play07:25

care pharmacy compounding pharmacy

play07:27

internet pharmacy and mail-order

play07:30

veterinary pharmacy nuclear pharmacy

play07:32

military pharmacy pharmacy informatics

play07:35

specialty pharmacy

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Pharmacy HistoryMedical DrugsPharmacologyPharmacy LawsDrug DevelopmentHealthcare EvolutionUS PharmacyPharmaceuticalsAncient MedicinePharmacy Practices