精神健康的祕密竟藏在腸道裡?這樣做改善精神狀態!

四維健康
1 Oct 202409:08

Summary

TLDR本视频探讨了肠道健康与大脑和心理健康的密切关系。杨医生指出,肠道微生物群通过迷走神经和代谢物直接影响大脑的认知、记忆、情绪调节等功能。此外,肠道健康与免疫功能、神经递质产生和全身炎症密切相关,肠道菌群失衡会导致心理疾病如抑郁症和焦虑症。通过补充益生菌、摄入抗炎饮食、减少压力和增加运动,可以改善肠道和大脑健康。建议通过肠道测试进行个性化健康管理,强调保护肠道即是保护大脑和整体健康。

Takeaways

  • 🧠 肠道健康与大脑健康密切相关,保持健康的肠道是维持良好心理健康的基础。
  • 🦠 肠道微生物群由有害、中性和有益细菌组成,平衡的微生物环境对肠道健康和全身健康至关重要。
  • 📡 通过迷走神经,肠道微生物群影响大脑功能,进而影响认知、记忆、注意力和情绪调节。
  • 🍎 短链脂肪酸如丁酸、丙酸和乙酸对大脑神经细胞有重要影响,能够穿过血脑屏障调节神经活动。
  • 🧫 肠道不健康会导致‘肠漏’,有害物质进入血液,引发全身炎症,增加患自闭症、抑郁症和焦虑症的风险。
  • 😌 肠道能产生神经递质,如血清素、多巴胺和GABA,但这些神经递质的代谢物会间接影响大脑活动。
  • 😷 临床研究表明,抑郁症患者的肠道中短链脂肪酸减少,肠道有害细菌增多,增加神经炎症和抑郁的风险。
  • 🦸 补充益生菌和益生元可以恢复肠道微生物平衡,减少炎症,改善情绪和认知。
  • 🥗 地中海饮食富含橄榄油、Omega-3和绿色蔬菜,有助于减少肠道炎症,维持肠道健康,并降低抑郁症的发病率。
  • 💡 通过肠道健康测试,可以为每个人制定个性化的肠道保护计划,帮助保持大脑和全身的健康。

Q & A

  • 为什么肠道健康对大脑和心理健康如此重要?

    -肠道与大脑通过多种机制密切相关。肠道微生物群通过迷走神经影响大脑功能,影响我们的认知、情绪调节、记忆等。此外,肠道产生的代谢物和神经递质也会影响大脑的神经活动,保持肠道健康有助于维持大脑和心理健康。

  • 什么是肠道微生物群?它如何影响我们的大脑?

    -肠道微生物群是肠道内存在的各种细菌,有益菌、中性菌和有害菌。它们通过维持肠道环境平衡,支持消化、吸收和毒素排泄。微生物群通过迷走神经和代谢物(如短链脂肪酸)影响大脑神经细胞,进而影响我们的情绪、认知和神经炎症反应。

  • 迷走神经在肠道和大脑的联系中起到了什么作用?

    -迷走神经是肠道和大脑之间的直接连接通道。研究表明,切断迷走神经后,肠道微生物群对大脑的影响会大大减少,说明迷走神经在肠道对大脑的影响中起到了至关重要的作用。

  • 什么是短链脂肪酸?它们如何影响大脑健康?

    -短链脂肪酸是肠道分解膳食纤维过程中产生的代谢物,主要包括丁酸、丙酸和乙酸。它们可以通过血液穿过血脑屏障,进入大脑。其中,丁酸能减少大脑的炎症反应,调节神经递质的活性,对大脑健康有积极影响。

  • 肠漏症是什么?它如何影响大脑和全身健康?

    -肠漏症是指肠道屏障功能受损,导致一些本不该进入血液的有害物质(如吲哚、对甲酚、脂多糖)渗漏进入血液。它们会引发全身性炎症反应,增加C反应蛋白、白细胞介素-6等炎症指标,进而影响大脑,增加抑郁、焦虑等心理问题的风险。

  • 肠道如何产生和影响神经递质?

    -肠道可以产生多种神经递质,如血清素、多巴胺和GABA(γ-氨基丁酸)。虽然这些神经递质不能直接穿过血脑屏障,但它们的代谢产物可以通过直接或间接的方式影响大脑的神经活动。因此,肠道微生物群的不平衡会影响神经递质的平衡,进而影响情绪和精神活动。

  • 肠道健康失衡如何与抑郁症和焦虑症相关?

    -研究发现,抑郁症患者的肠道中产生短链脂肪酸的有益菌减少,而有害菌增多,导致神经炎症增加,从而诱发抑郁症。焦虑症患者和肠易激综合征患者的肠道菌群也表现出失衡,且肠道屏障功能受损严重。

  • 哪些饮食和生活方式有助于保护肠道健康?

    -增加益生菌和益生元的摄入有助于恢复肠道菌群平衡。益生菌如双歧杆菌和乳酸菌可以减少炎症,改善情绪和认知。抗炎饮食如地中海饮食(富含橄榄油、Omega-3、蔬菜和坚果)有助于减少肠道炎症。此外,减少压力、增加运动也能调节神经递质,改善肠道健康。

  • 益生菌和益生元之间有什么区别?

    -益生菌是有益于肠道健康的活性细菌,如双歧杆菌和乳酸菌,它们可以帮助恢复肠道菌群平衡。益生元则是益生菌的营养来源,通常是一些特殊的膳食纤维,如菊粉和低聚果糖。益生元为益生菌提供营养,促进其生长。

  • 为什么某些人群更容易出现肠道菌群失衡?

    -肠道菌群受到多种因素影响,包括出生方式、饮食结构、情绪压力等。比如,剖腹产出生的婴儿因为没有经过产道,未能获得母亲的益生菌,因此更容易出现肠道菌群失衡。此外,长期压力和不健康的饮食也会导致肠道健康受损。

Outlines

00:00

🧠 肠道健康与大脑的复杂联系

在本段中,杨医生介绍了肠道健康与大脑健康之间的密切联系。她解释道,肠道中的微生物群通过迷走神经直接影响大脑功能,影响我们的认知、记忆、注意力、学习能力和情绪调节。此外,肠道中的短链脂肪酸,如丁酸、丙酸和叶酸,可以穿透血脑屏障,影响大脑的神经细胞,调节神经递质活性。肠道的免疫功能也起着重要作用,当肠道屏障受损时,可能会导致脑部炎症和情绪失调。

05:02

🤔 临床证据:肠道健康与心理疾病的关系

这段讨论了肠道健康与多种心理疾病(如抑郁症、焦虑症、自闭症、精神分裂症和双相情感障碍)之间的临床证据。研究表明,抑郁症患者的短链脂肪酸减少,且有害细菌的增殖会导致神经炎症。此外,自闭症患者的肠道代谢物,如丙酸和对甲酚等水平较高,精神疾病药物也常导致肠道菌群失衡。为了保护大脑健康,补充益生菌和益生元、采用抗炎饮食(如地中海饮食)以及进行肠道测试和分析被提议作为有效措施。

Mindmap

Keywords

💡肠道健康

肠道健康指的是肠道菌群平衡和功能正常的状态。视频中强调,肠道健康直接影响大脑和心理健康,尤其是通过神经系统和代谢途径。维持肠道健康可以通过摄入益生菌、膳食纤维以及抗炎饮食等方式实现。

💡微生物群

微生物群是指肠道内存在的多种细菌、病毒和真菌。视频中提到,肠道内的微生物群分为有害菌、无害菌和中性菌,它们共同维持肠道的平衡。微生物群的失衡可能导致神经炎症,从而影响心理健康。

💡迷走神经

迷走神经是从肠道连接到大脑的主要神经通道,直接影响大脑的认知和情绪调节。视频中讲述,切断迷走神经会大大减少肠道对大脑的影响,显示其在肠脑轴中的重要性。

💡短链脂肪酸

短链脂肪酸是肠道分解膳食纤维时产生的重要代谢物,主要包括丁酸、丙酸和乙酸。视频中提到,短链脂肪酸可以穿透血脑屏障,减少大脑炎症并调节神经递质活动。

💡肠脑轴

肠脑轴是指肠道与大脑之间的双向通信系统,涉及迷走神经、短链脂肪酸和神经递质等因素。视频强调,肠道健康对大脑的情绪调节、认知功能和神经活动有直接影响。

💡肠漏综合症

肠漏综合症是指肠道屏障受损,导致有害物质进入血液,引发全身炎症反应。视频中指出,肠漏综合症会增加炎症标志物如C反应蛋白的水平,进而影响大脑的健康。

💡神经递质

神经递质是指在神经元之间传递信号的化学物质,常见的包括血清素、多巴胺和GABA。视频中提到,肠道可以产生这些神经递质的代谢物,间接影响大脑的神经活动。

💡抑郁症

抑郁症是一种常见的心理障碍,视频中提到,抑郁症患者的肠道内短链脂肪酸减少,且有害细菌增多,导致神经炎症和情绪紊乱。补充益生菌被认为有助于缓解抑郁症状。

💡益生菌

益生菌是指对肠道健康有益的细菌,常见的有双歧杆菌和乳酸菌。视频中强调,益生菌可以帮助恢复肠道菌群平衡,减少炎症,进而改善情绪和认知功能。

💡地中海饮食

地中海饮食是一种富含橄榄油、欧米茄-3脂肪酸、绿叶蔬菜和坚果的饮食方式,具有抗炎作用。视频中指出,长期坚持地中海饮食可以降低抑郁的风险,维持肠道和大脑健康。

Highlights

健康是我们最大的财富,我们必须先保持健康的肠道,以维持大脑健康。

肠道微生物组通过迷走神经直接影响大脑功能,影响认知、记忆、注意力和情绪调节。

短链脂肪酸(如丁酸)可以穿过血脑屏障,减少大脑的炎症反应,调节神经递质活动。

肠道不健康时,肠道屏障受损,导致有害物质(如吲哚、对甲酚)进入血液,引发全身炎症,包括脑部。

肠道菌群失衡会导致神经递质失衡,影响情绪和精神活动,如GABA水平低与抑郁、焦虑风险增加有关。

研究发现,抑郁症患者的肠道短链脂肪酸生成减少,有害菌增多,引发神经炎症。

焦虑症和肠易激综合症患者的肠道菌群失衡率较高,肠道屏障功能损伤严重。

自闭症患者的肠道代谢物如丙酸、对甲酚和吲哚水平较高,说明肠道代谢与神经疾病相关。

补充益生菌(双歧杆菌、乳酸菌)和益生元(菊粉、低聚果糖)有助于恢复肠道菌群平衡,减少炎症,改善情绪和认知。

地中海饮食富含橄榄油、欧米伽-3、绿色蔬菜和坚果,能帮助减少肠道炎症,维持肠道健康,降低抑郁发病率。

研究发现,长期坚持地中海饮食能调节情绪,减轻压力,增强认知功能,减少肠道菌群失衡。

剖腹产出生的人肠道菌群失衡率较高,因为没有通过产道获得益生菌。

每个人的肠道健康受到先天因素、饮食习惯、情绪压力和生活环境的影响。

建议进行肠道检测和分析,以制定个性化的肠道健康保护计划。

保护肠道健康即是保护大脑健康,也是在保护全身的健康。

Transcripts

play00:00

We talk about mental health and brain health

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It is closely related to our gastrointestinal tract

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In other words

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If we want to maintain a healthy brain and mental health

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We must first maintain a healthy intestine

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Health is our greatest wealth

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Let's take care of it

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I am Dr. Yang

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Why is intestinal health so important

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How does it affect

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our brain and mental activities

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How can we do this

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more effectively

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to protect our brains and mental activities

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Today we will discuss this topic in depth with you

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If you want to see more videos like this

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Please click on the subscription and bell

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We will continue to provide you with

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professional, objective and comprehensive health information

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Let's first look at

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our intestines and brain

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What kind of complex relationship is this?

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First, we need to look at the microbiome in our intestines

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The relationship with the central nervous system

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There are various kinds of bacteria in our intestines

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Some are harmful

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There are harmless ones

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There are neutral ones

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These three categories

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Then these three categories of bacteria

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It constitutes a complete and balanced bacterial environment

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This environment is good for the health of our intestines

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Digestion and absorption

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and excreting toxic and useless substances

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from the body

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all play a very important role

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So both traditional Chinese medicine

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and modern medicine have recognized

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If your gastrointestinal tract is not healthy

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Your entire body, including your brain, will not be healthy

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The first function of the microbiome

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It passes through the vagus nerve in our intestines

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and directly affects the function of our brain

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It affects our cognition

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It affects our memory

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Our attention and learning abilities

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It also affects our emotional regulation

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In terms of research

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We cut off the vagus nerve

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The intestinal microbiome

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has a much smaller impact on the brain

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This shows that the vagus nerve

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plays a crucial role

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The second factor here

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is that the intestines produce some important metabolites during the digestion process

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and produce some important metabolites

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Among these metabolites

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there are two things

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that we should pay special attention to

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A short-chain fatty acid

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It is produced in the process of breaking down

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dietary fiber

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There are folic acid, propionic acid and butyric acid

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All three of these things can pass through the blood

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and penetrate the blood-brain barrier

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Entering the brain

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This then has an important impact on the brain's nerve cells

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For example, folic acid

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It can reduce the brain's inflammatory response

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It can also regulate the activity of neurotransmitters

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It is a very good short-chain fatty acid

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Propionic acid is interesting

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Its good side

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It can help sugar metabolism and fat metabolism

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But its bad side

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If it's too high

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It can cause damage to the nervous system

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It's strongly associated with autism

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In some patients with depression

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We found it in the gut bacteria that produce butyrate

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It is relatively small

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It can be seen that butyrate is closely related to our neurotransmitters and emotional regulation

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The second part is immune function

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The intestine is the most active place for immune function

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If the intestinal flora is out of balance

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it will cause damage to the intestinal mucosa

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that is, the intestinal barrier is damaged

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so many things that should not enter the blood

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will leak in

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That's why it's called leaky gut

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Many of these things are harmful

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For example, indole

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We talked about paracresol

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Also lipopolysaccharide

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These enter the blood

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It will cause inflammation throughout the body

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including the brain

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If we test their blood

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we will find that some inflammatory indicators will increase

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such as C-reactive protein

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interleukin-6

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Tumor necrosis factor alpha

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It will increase all of these

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At the same time, it will increase autism

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The risk of depression and anxiety

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The third factor is that it produces neurotransmitters

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Everyone knows that

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Our intestines can produce a variety of neurotransmitters

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For example, serotonin

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dopamine GABA aminobutyric acid

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These neurotransmitters themselves

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cannot directly penetrate the blood-brain barrier

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and enter the brain

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but their metabolites

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can directly or indirectly

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It affects the brain's neural activity

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So intestinal flora imbalance

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cause an imbalance in neurotransmitters

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It also affects our mental activities

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For example, some studies have found that

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Bacteria that produce GABA in the intestines

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People with a lower risk of GABA

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depression and anxiety are more common

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because the intestines pass its metabolites

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into the brain

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Immune function of the brain

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The impact of neurotransmitter activity

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And the immune response of the intestines causing leaky gut

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Inflammation of the brain caused by the intestines

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Neurotransmitters in the intestines

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Directly and indirectly, it affects

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the activity of neurotransmitters in the brain

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These four mechanisms

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closely link the health of the intestines and the health of the brain

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together

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So, such a result

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Do we have clinical evidence?

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Let's take a look

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First, depression

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The intestines of people with depression produce less short-chain fatty acids

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In addition, the proliferation of harmful bacteria

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will also increase neuroinflammation

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and induce depression

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A study analyzed 50 patients with depression

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and found that beneficial bacteria in the body

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like Lactobacillus Bifidobacterium is significantly reduced

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Anxiety disorder

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And patients with irritable gastrointestinal syndrome

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Their intestinal flora is dysbiotic

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The proportion of intestinal barrier function damage is very high

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Another example is patients with autism

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Their intestinal propionic acid, p-cresol, indole

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These metabolites are all high

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Even patients with schizophrenia and bipolar disorder

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have imbalanced intestinal flora

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I want to talk about this in particular.

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The antipsychotic drugs these patients take

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often cause intestinal flora imbalance

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So the relationship between them is

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a relationship that has a negative impact on each other

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So what can we do?

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To keep our intestines healthy

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And then protect the health of our brains and mental activities

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First of all, we are already unbalanced

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So the most direct and simple way is

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It is to supplement probiotics and prebiotics

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Probiotics are mainly bifidobacteria and lactobacilli

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These probiotics can quickly help

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restore the balance of intestinal flora

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reduce inflammation

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Improve our mood and cognition

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What are prebiotics?

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It actually provides nutrition for probiotics

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It does this through some special dietary fibers

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Like inulin and oligofructose

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They can help the growth of probiotics

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restore the balance of intestinal microbiota

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So clinical studies have found

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If we give autistic children

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probiotics

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It will improve his social behavior

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Another thing is to increase the anti-inflammatory diet

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Like the Mediterranean diet

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It is rich in olive oil Omega-3

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Green vegetables and nuts

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These can help

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reduce inflammation in the intestines

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maintain intestinal health

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Studies have found that

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long-term consumption of a Mediterranean diet

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It can reduce the incidence of depression

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It can also regulate our emotions

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Reduce stress and increase exercise

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Both of these have direct effects on regulating neurotransmitters, both for the brain and the intestines

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00:07:58,633 It can improve our cognition

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It also reduces intestinal flora imbalance

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Reduce inflammation

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Each of our intestines

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is affected by its innate qualities

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For example, if someone had a caesarean section

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then the proportion of intestinal flora imbalance is very high

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because he did not pass through the birth canal

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to get these probiotics

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The second is diet

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Each of us has a different diet

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The third is our emotions

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Mental stress and living environment

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So if you really want to understand the health of your intestines

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You still need to do an intestinal test and analysis

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In this way, we can make a more individualized plan for protecting the intestinal health.

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We can formulate a plan for protecting the intestinal health for everyone.

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In short,

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Protecting the health of the intestines

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is to protect the health of the brain.

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It also protects the health of the whole body

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So I hope that all friends will pay attention to it

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Thank you for watching our program

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What are your experiences and insights in this regard?

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And any questions?

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Please share with us in the comment section.

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We also hope that everyone can support our channel by subscribing, forwarding and liking

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Continue to provide you with better

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more comprehensive information

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Understand the world and protect your health

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See you next time

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