Sistem Imun-Materi Biologi Kelas XI SMA

FKIP UNIVERSITAS RIAU
3 Oct 202109:37

Summary

TLDRThis educational video from the online learning team at Sriwijaya University covers the immune system, a topic in 11th-grade biology. The video explains the body's defense mechanisms, including non-specific and specific defenses, and details the functions of skin, mucosa, phagocytes, and inflammation. It also discusses specific immunity involving lymphocytes, the role of antibodies, and the difference between active and passive immunization. The goal is to help students understand how the body fights off pathogens and maintains health, with practical examples like COVID-19 vaccines and maternal antibody transfer.

Takeaways

  • 😷 The script introduces the topic of the human immune system, specifically for high school biology students learning about it in class 11.
  • 🛡️ It explains the immune system's role in defending the body against diseases like the flu and common cold.
  • 🧬 The script defines key immunology terms such as 'antibodies', 'antigens', and 'pathogens', explaining their function in the immune response.
  • 💊 The body's defense mechanisms are categorized into nonspecific and specific defenses, with nonspecific defenses being the body's first line of defense against various infections.
  • 🚫 Nonspecific defenses do not target a specific pathogen but instead respond to any foreign substance that enters the body, such as the skin and mucous membranes.
  • 🧬 The script details the role of specific immune defenses, which include T-lymphocytes and B-lymphocytes, and their functions in recognizing and remembering pathogens that have previously attacked the body.
  • 🤒 The body's response to pathogens includes inflammation and fever, which are part of the nonspecific defense mechanisms to fight off infections.
  • 💉 The concept of immunization is discussed, highlighting the difference between passive and active immunization and their importance in boosting immunity.
  • 🏥 Active immunization involves the body actively producing antibodies after vaccination, such as the COVID-19 vaccines mentioned in the script.
  • 🩺 Passive immunization can occur naturally, like antibodies passed from mother to child through the placenta and breast milk, or artificially through injections of immunoglobulins.
  • 🌟 The script concludes with a reminder for viewers to maintain their health and immunity, encouraging continued learning and wishing the information was beneficial.

Q & A

  • What is the main topic of the video script?

    -The main topic of the video script is the human immune system, specifically focusing on the functions of the immune system, types of body defenses, and types of immunity.

  • Who are the members of the online learning media team from the University of Sriwijaya?

    -The members of the online learning media team from the University of Sriwijaya are Annisa Salsabila, Andini, and Y Diastuti, with Ibu Dokter Yeni Anwar as their advisor.

  • What are the indicators achieved in the script that students should be able to explain?

    -The indicators achieved in the script include students being able to explain the function of the immune system, identify the types of body defenses correctly, and explain the types of immunity accurately.

  • What is an antigen according to the script?

    -An antigen is a substance such as a protein or carbohydrate that can stimulate the production of antibodies when introduced into the body, such as toxins or enzymes.

  • What is a pathogen as described in the script?

    -A pathogen is a substance or agent that can cause disease in humans.

  • What are the two main types of body defenses mentioned in the script?

    -The two main types of body defenses mentioned in the script are nonspecific immunity and specific immunity.

  • What is the function of the skin as part of the nonspecific immunity?

    -The skin, as part of nonspecific immunity, acts as the first line of defense by providing a tight barrier that is difficult for pathogens to penetrate.

  • What is the role of lysozyme in the body's defense mechanism?

    -Lysozyme is an antimicrobial protein that can be found in sweat, saliva, tears, and breast milk, which can break down the peptidoglycan layer of bacterial cell walls, thus aiding in the destruction of pathogens.

  • What is the difference between nonspecific and specific immunity?

    -Nonspecific immunity is the body's general defense against various infections without involving a selection and memory process for specific pathogens. Specific immunity, on the other hand, is the body's defense function against specific pathogens and has the ability to recognize and remember pathogens that have previously attacked the body.

  • What are the two types of lymphocytes mentioned in the script and their functions?

    -The two types of lymphocytes mentioned are T lymphocytes and B lymphocytes. T lymphocytes include cytotoxic T cells that destroy bacteria, viruses, and other pathogens; helper T cells that activate cytotoxic T cells and trigger antibody production; suppressor T cells that suppress antibody production; and memory T cells that remember antigens. B lymphocytes are responsible for forming the humoral immune system, creating memory cells, and forming long-term immunity.

  • What are the two types of immunization discussed in the script and how do they differ?

    -The two types of immunization discussed are passive and active immunization. Active immunization involves the body actively producing antibodies as a form of resistance to disease after vaccination. Passive immunization, on the other hand, is when the body can directly obtain immunity, not originating from within, such as through the transfer of antibodies from mother to fetus or through injections of immunoglobulins.

Outlines

00:00

🛡️ Introduction to the Immune System

The video script begins with a greeting and an introduction to the online learning team from the University of Sriwijaya, consisting of Annisa Salsabila, Andini, and Y Diastuti, with Dr. Yeni Anwar as the advisor. They aim to teach about the immune system, a topic covered in the 11th-grade Biology curriculum. The script outlines the learning objectives: explaining the body's defense mechanisms, identifying types of body defenses, and understanding different types of immunity. It introduces basic immunology terms such as antigens, pathogens, and antibodies, and explains the body's innate ability to fight off diseases and maintain health.

05:00

🌡️ Nonspecific and Specific Body Defenses

This paragraph delves into the body's nonspecific defenses, which are the first line of defense against various infections without involving a selection process or memory of specific pathogens. It describes the skin and mucous membranes as barriers that prevent pathogens from entering the body. Additionally, it discusses the role of antimicrobial proteins like lysozyme in bodily fluids such as sweat, saliva, and breast milk. The paragraph also explains the second line of defense, which includes phagocytic cells and inflammation as a response to tissue damage caused by infection or other irritants. It further elaborates on the specific immune system's ability to recognize and remember pathogens that have previously invaded the body, detailing the roles of T-lymphocytes and B-lymphocytes in the adaptive immune response.

💉 Types of Immunization

The final paragraph discusses the methods of enhancing immunity through immunization. It differentiates between passive and active immunization. Active immunization involves the body's production of antibodies in response to vaccination, providing long-term immunity against specific diseases. The script provides examples of active immunization, such as COVID-19 vaccines from various manufacturers. Passive immunization, on the other hand, provides immediate but temporary immunity, either naturally through maternal antibodies transferred to the fetus or artificially through the administration of immunoglobulins. The team concludes with a message to maintain good health and immunity, encouraging continuous learning and wishing the audience well.

Mindmap

Keywords

💡Immune System

The immune system is a complex network of organs, cells, proteins, and tissues that work together to defend the body against infections and diseases. In the video, it is the central theme as it discusses how the body's immune system functions to protect against pathogens and maintain health. The script mentions the immune system's response to common illnesses like the flu and how it can recognize and destroy abnormal cells such as cancer cells.

💡Antibody

An antibody is a protein produced by the body's immune system as a response to the presence of an antigen. In the script, antibodies are described as immunoglobulins or glycoproteins that help identify and neutralize foreign substances. The video explains their role in the immune response, such as how they are produced in reaction to an antigen and their function in the body's defense mechanisms.

💡Antigen

An antigen is any substance that the immune system recognizes as foreign and potentially harmful, such as proteins, toxins, or carbohydrates. The script uses the term to illustrate what triggers the production of antibodies. For example, when a pathogen enters the body, it is identified as an antigen, prompting the immune system to produce antibodies to fight it off.

💡Pathogen

A pathogen is a microorganism, such as a bacterium, virus, or fungus, that can cause disease. The video script explains that everyone can be affected by pathogens, but the immune system has mechanisms to fight them off and help the body recover. The term is used to describe the foreign agents that the immune system must defend against.

💡Nonspecific Defense

Nonspecific defense, also known as innate immunity, is the body's first line of defense against infections. It includes physical barriers like skin and mucous membranes, as well as chemical barriers like antimicrobial substances in bodily fluids. The script explains that nonspecific defenses do not involve a selection process or memory of specific pathogens, unlike specific defenses.

💡Inflammation

Inflammation is the body's response to harmful stimuli, such as pathogens or damaged cells. It is characterized by symptoms like redness, heat, pain, and swelling. In the video, inflammation is mentioned as a reaction to infection and includes fever as an example, where the body's temperature rises to weaken bacteria and viruses, aiding in recovery.

💡Phagocyte

Phagocytes are a type of white blood cell that can engulf and digest foreign particles or pathogens. The script describes phagocytes as part of the body's second line of defense, working to eliminate invaders that have penetrated the first line of defense.

💡Lymphocyte

Lymphocytes are a type of white blood cell that plays a crucial role in the immune response. The video script distinguishes between T lymphocytes and B lymphocytes. T lymphocytes are involved in cell-mediated immunity, while B lymphocytes are responsible for producing antibodies and contributing to humoral immunity.

💡Vaccination

Vaccination is a process of introducing a vaccine into the body to stimulate the immune system to produce antibodies against specific diseases. The script explains two types of vaccination: active and passive. Active vaccination involves the body producing its own antibodies, as in the case of COVID-19 vaccines mentioned in the script, while passive vaccination involves the direct introduction of antibodies from an external source.

💡Imunisasi

Imunisasi, the Indonesian term for 'vaccination,' is discussed in the script as a method to enhance immunity. It is presented as a way to prevent diseases by introducing a vaccine that trains the immune system to recognize and fight specific pathogens. The script provides examples of both active and passive immunization.

💡Memory Cells

Memory cells are a type of immune cell that 'remembers' pathogens the body has previously encountered. If the same antigen re-enters the body, memory cells quickly trigger an immune response. The script mentions memory cells in the context of specific immunity, emphasizing their role in long-term immunity and rapid response to recurring infections.

Highlights

Introduction to the online learning team from Escape, Sriwijaya University, discussing the immune system.

The material on the immune system is part of the Biology curriculum for 11th-grade high school students, covered in KD 3.14 and 4.14.

Learning objectives include explaining the body's defense mechanisms, identifying types of body defenses, and understanding different types of immunity.

Discussion on how the body's immune system responds to common illnesses like the flu or colds.

Explanation of the terms immunology, antigen, and pathogen, and their roles in the immune response.

The body's innate ability to fight off diseases and the concept of nonspecific and specific body defenses.

Nonspecific body defenses act against various infections without targeting specific pathogens.

The skin and mucous membranes serve as the first line of defense against pathogens.

Antimicrobial substances such as lysozyme in sweat, saliva, and breast milk contribute to the body's first line of defense.

Coughing, sneezing, and tearing are responses to expel foreign substances and are part of the body's nonspecific defense mechanisms.

If the first line of defense is breached, the second line of defense, including phagocytic cells and inflammation, comes into play.

Inflammation is a response to tissue damage caused by infection, chemicals, or physical disturbances, such as fever as a sign of the body fighting off pathogens.

Introduction to specific body defenses, which are capable of recognizing and remembering specific pathogens.

Lymphocytes, including T-cells and B-cells, play a crucial role in the body's specific immune response.

T-cells are formed in the bone marrow and mature in the thymus, with various types each having a specific function in the immune response.

B-cells are responsible for forming the humoral immune system, creating memory cells, and long-term immunity.

The immune system's ability to remember previous antigens and quickly produce antibodies upon re-exposure for enhanced defense.

Discussion on how the body can overcome and enhance immunity, including the process of immunization.

Differences between passive and active immunization, with examples of each type.

Active immunization involves the body actively producing antibodies after vaccination, such as COVID-19 vaccines.

Passive immunization can occur naturally, like antibodies transferred from mother to fetus, or artificially through injections.

Encouragement to maintain good health and immunity, and a message to continue learning and applying the knowledge gained.

Transcripts

play00:00

Halo

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[Musik]

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assalamualaikum warahmatullahi

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wabarakatuh Halo teman-teman kami dari

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tim media pembelajaran online Escape

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Universitas Sriwijaya yang beranggotakan

play00:09

Annisa Salsabila mimpi tidak Andini dan

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Y Diastuti dengan dosen pembimbing Ibu

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Dokter Yeni Anwar mpd

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[Musik]

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disini kami akan mengajak kalian untuk

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belajar bersama mengenai sistem imun

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materi sistem imun merupakan materi

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Biologi SMA kelas 11 yang termuat dalam

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KD 3.14 dan 4.14

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Adapun indikator yang dicapai yaitu

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siswa dapat menjelaskan fungsi sistem

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pertahanan tubuh dengan baik siswa dapat

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Mengidentifikasi jenis pertahanan tubuh

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dengan benar dan siswa dapat menjelaskan

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jenis imunitas dengan benar

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sebelumnya Kalian pasti pernah kan

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terserang penyakit seperti demam flu

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atau pun tiba-tiba bersin

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Hai apakah kalian menyadari bahwa semua

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hal tersebut merupakan suatu mekanisme

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dari sistem pertahanan tubuh kita

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sebenarnya Bagaimana sih dengan sebagian

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orang yang mampu bertahan sehat dan

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tidak terserang penyakit

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hal apa saja yang berkaitan dengan

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kemampuan tersebut serta apa sih

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sebenarnya istilah imun patogen antibodi

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serta vaksin yang selama ini banyak

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diperbincangkan

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Hai agar kita lebih paham dengan materi

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ini yuk kita cari tahu dulu tentang

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istilah imunologi nya

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antibodi merupakan protein imunoglobulin

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atau molekul glikoprotein yang

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dihasilkan tubuh sebagai reaksi akibat

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masuknya suatu antigen

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antigen merupakan senyawa protein atau

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karbohidrat seperti toksin atau enzim

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yang merangsang terbentuknya antibodi

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bila diinjeksikan kedalam tubuh

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patogen merupakan benda atau bahan yang

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dapat menimbulkan penyakit pada manusia

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faktanya Semua orang bisa terserang

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penyakit namun juga bisa sembuh dari

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penyakit yang menyerang tubuh hal itu

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dikarenakan tubuh kita mempunyai sistem

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pertahanan tubuh yang berfungsi

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mempertahankan tubuh dari patogen dan

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Agan eksternal seperti debu serbuk sari

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rambut binatang

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dapat menyingkirkan sel-sel yang rusak

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serta mengenali dan menghancurkan sel

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abnormal seperti sel kanker dalam

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menanggapi berbagai jenis patogen

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manusia memiliki berbagai jenis

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pertahanan tubuh yang dapat

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dikelompokkan menjadi pertahanan tubuh

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nonspesifik dan pertahanan tubuh

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spesifik

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[Musik]

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Tapi sebelumnya Apa sih yang dimaksud

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dengan non spesifik itu pertahanan tubuh

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nonspesifik berfungsi untuk melawan

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berbagai jenis infeksi yang umum terjadi

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tanpa melibatkan adanya proses seleksi

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dan memori terhadap jenis patogen

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tertentu

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artinya disini bahwa pertahanan tubuh

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nonspesifik tidak terfokus hanya pada

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satu antigen tertentu melainkan seluruh

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benda asing yang bersifat patogen dan

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masuk ke dalam tubuh akan direspon oleh

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sistem pertahanan tubuh nonspesifik ini

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untuk melindungi tubuh kita sistem

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pertahanan nonspesifik terdiri dari

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beberapa bagian yang berfungsi sebagai

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garis pertahanan pertama

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untuk terdiri dari kulit yang dengan

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mukosa dan zat antimikroba

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Mengapa kulit digolongkan sebagai garis

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pertahanan pertama

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dia Hal ini dikarenakan kulit sebagai

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lapisan eksternal memiliki susunan sel

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epidermisnya yang sangat rapat sehingga

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menyulitkan patogen untuk masuk ke tubuh

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kita Begitu juga dengan sel mukosa yang

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melapisi saluran pencernaan saluran

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respirasi saluran kelamin dan saluran

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ekskresi yang tidak dapat ditembus oleh

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bakteri dan virus Karena antara satu

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membran dan membran lain sangat rapat

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Hai selanjutnya kulit mampu

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mensekresikan protein antimikroba

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seperti lisozim yang terkandung pada

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keringat air ludah air mata dan air susu

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ibu atau ASI

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zat kimia tersebut dapat menghancurkan

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lapisan peptidoglikan pada dinding sel

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bakteri

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Nah itulah mengapa ketika kita bersin

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atau batuk mengeluarkan cairan kental

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itu artinya sistem pertahanan tubuh

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pertama kita telah menanggapi dan

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merespon benda asing tersebut dan

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mengeluarkannya kembali

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begitu juga saat mata kemasukan benda

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asing maka akan mengeluarkan air mata

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sebagai bentuk perlindungan terhadap

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benda asing tersebut

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Hai Namun apabila garis pertahanan

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pertama mampu ditembus oleh patogen Maka

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selanjutnya garis pertahanan kedua yang

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akan mulai bekerja beberapa diantaranya

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adalah sel-sel fagosit dan juga

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informasi

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pada pertahanan tubuh kedua ini share

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fagosit akan menelan dan mencerna benda

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asing yang masuk ke dalam tubuh

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sedangkan inflamasi atau peradangan

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diartikan sebagai reaksi terhadap

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kerusakan sel-sel tubuh oleh adanya

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infeksi zat kimia dan gangguan fisik

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lainnya salah satu contoh respon tubuh

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akibat peradangan yaitu demam ketika

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demam suhu tubuh akan naik sampai

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melebihi Suhu tubuh normal suhu tubuh

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yang tinggi di satu sisi akan

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menguntungkan karena bakteri dan virus

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akan lemah sehingga seiring waktu tubuh

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akan menjadi pulih kembali setelah kita

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mengetahui sistem pertahanan tubuh

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nonspesifik

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selanjutnya Mari kita bahas sistem

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pertahanan tubuh secara spesifik

play05:43

pertahanan tubuh spesifik merupakan

play05:45

pertahanan tubuh fungsi untuk melawan

play05:48

jenis patogen tertentu pertahanan tubuh

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spesifik memiliki kemampuan untuk

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mengenali dan mengingat patogen yang

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pernah menyerang tubuh kita

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sebagai garis pertahanan ketiga jenis

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pertahanan tubuh spesifik ini Contohnya

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yaitu pada limfosit yang terdiri dari

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sel limfosit t dan sel limfosit B sel

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limfosit t dibentuk di sumsum tulang

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belakang namun rumah tangannya terjadi

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di kelenjar thymus

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terdapat empat jenis sel limfosit yaitu

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sel t sitotoksik yang berfungsi

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menghancurkan bakteri virus dan patogen

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lainnya sel t penolong yang berfungsi

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mengaktifkan sel t sitotoksik dan memicu

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produksi antibodi sel t supresor yang

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berfungsi menekan produksi antibodi dan

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sel t memori yang berfungsi mengingat

play06:40

antigen yang pernah menyerang tubuh sel

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limfosit B deposit B dibentuk dan

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dimatangkan di sumsum yang belakang dan

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ketika sudah matang akan menyebar ke

play06:50

seluruh tubuh

play06:52

sel limfosit B berfungsi membentuk

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sistem kekebalan humoral membentuk sel

play06:57

memori dan membentuk sistem kekebalan

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tubuh dalam jangka panjang

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jika pada suatu saat antigen yang sama

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masuk kembali ke dalam tubuh maka sel

play07:09

memori akan segera memicu pembentukan

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antibodi oleh sel B plasma

play07:15

setelah mengetahui bagaimana Fungsi dan

play07:18

jenis pertahanan tubuh dalam mengatasi

play07:20

virus dan patogen lainnya Tidakkah

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kalian penasaran Bagaimana cara tubuh

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dalam mengatasi dan meningkatkan

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imunitas

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Hai

play07:30

imunitas dapat ditingkatkan dengan cara

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imunisasi Kalian pasti sudah melakukan

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imunisasi sebelumnya

play07:39

imunisasi terdapat dua jenis yaitu

play07:42

imunisasi pasif dan aktif Nah apa sih

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perbedaan imunisasi pasif dan aktif itu

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pada imunisasi aktif tubuh secara aktif

play07:54

menghasilkan antibodi sebagai bentuk

play07:56

kekebalan tubuh terhadap penyakit

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setelah seseorang mendapatkan vaksinasi

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vaksinasi merupakan proses memasukkan

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vaksin ke dalam tubuh supaya tubuh

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membentuk antibodi sehingga kebal

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terhadap suatu penyakit

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contoh dari imunisasi aktif adalah

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pemberian vaksin covert nine ten

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vaksin covert nineteen yang banyak

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digunakan untuk menangani virus korona

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adalah si novak astrazeneca si novam

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moderna dan fiz-r

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sementara pada bisa sih pasif kekebalan

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tubuh bisa langsung didapatkan karena

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tidak berasal dari dalam tubuh

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situasi ini dapat terjadi secara alami

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dan buatan

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contoh imunisasi pasif secara alami

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yaitu pemberian antibodi dari tubuh ibu

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hamil kepada janin dalam kandungannya

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melalui plasenta dan tali pusat ketika

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lahir didapatkan dari ASI eksklusif

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melalui proses menyusui

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contoh imunisasi pasif secara buatan

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yaitu pemberian immunoglobulin pada

play09:06

tubuh melalui penyuntikan

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Hai Nah itulah tadi beberapa pembahasan

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kita mengenai fungsi sistem pertahanan

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tubuh jenis pertahanan tubuh dan juga

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jenis-jenis imunisasi

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gimana tentunya kalian sudah paham kan

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sekarang mengenai materi kita pada hari

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ini pesan dari kami untuk selalu jaga

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kesehatan dan imunitas tubuh kalian ya

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semangat belajar dan semoga bermanfaat

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[Musik]

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Immune SystemBiology EducationHealth DefenseAntigensAntibodiesVaccinationDisease PreventionImmunologyHealthcareEducational ContentImmunity Types