Photobiomodulation Devices and Research (including Long COVID)

Summary

本视频深入探讨了光生物调节（photobiomodulation）这一快速发展的科学领域，特别是其在健康领域的应用。光生物调节利用特定波长的光来影响人体细胞，从而调节激素、增强巨噬细胞活性、减少炎症等。视频中特别关注了光生物调节在治疗长期COVID-19症状中的潜力，包括其对线粒体功能的积极影响。此外，介绍了市面上的光生物调节设备，如近红外光头盔，以及它们在治疗脑损伤、抑郁、焦虑和长期COVID-19中的潜在效果。

Takeaways

• 🌞 光生物调节（photobiomodulation）是利用光在健康领域的应用，涉及使用特定波长的光来影响细胞功能。
• 🧠 光生物调节特别关注于脑光生物调节，即利用光来改善大脑功能，可能对长期新冠症状有潜在益处。
• 📈 从1980年至今，光生物调节领域的研究数量呈指数级增长，显示出这一科学领域的快速发展。
• 🔍 光生物调节可以影响多种生理过程，包括激素调节、免疫反应、抗微生物效果、细胞保护和细胞信号传导。
• 🛑 光生物调节对线粒体功能有显著影响，这与长期新冠症状中的线粒体功能障碍有关。
• 💡 近红外光能够深入身体内部，影响线粒体，可能有助于减少氧化应激和改善线粒体功能。
• 🧪 研究表明，近红外光可以改善新冠患者的住院时间、肺功能和血液学指标。
• 🤔 尽管光生物调节显示出巨大潜力，但目前还没有FDA批准的设备，且研究仍在进行中。
• 🎓 光生物调节设备如Neuronics和vLight正在寻求FDA批准，并进行临床试验以支持其安全性和有效性。
• ⚠️ 光生物调节设备使用需谨慎，应在专业人士的指导下进行，以确保安全和效果。

Q & A

什么是光生物调节疗法（photobiomodulation）？

光生物调节疗法是指使用光来影响健康的一种科学领域，它涉及使用特定波长的光来调节生物体内的生化反应，从而促进伤口愈合、组织再生、增加循环、减少炎症和疼痛，以及帮助恢复正常的细胞功能。

光生物调节疗法在治疗新冠长期症状（long covid）方面的潜力是什么？

光生物调节疗法，特别是近红外光的使用，被认为可以改善新冠长期症状，如疲劳和脑雾。这与光疗法能够减少氧化应激、刺激褪黑激素产生以及改善线粒体功能有关。

近红外光如何影响线粒体功能？

近红外光能够激活线粒体代谢，促使细胞从依赖糖酵解转向氧化磷酸化，这一转变有助于干细胞离开其缺氧微环境，寻找足够的氧气以支持能量产生，进而分化为可以修复大脑的细胞。

光生物调节疗法设备是否已经获得FDA批准？

目前，光生物调节疗法设备尚未获得FDA批准。两家主要公司，neurionic和vlight，正在努力获得FDA对其设备的认可，这可能需要2到3年的时间。

光生物调节疗法设备通常用于哪些医疗条件？

光生物调节疗法设备被研究用于多种医疗条件，包括阿尔茨海默病、脑损伤、抑郁症、焦虑症、新冠长期症状等。

为什么光生物调节疗法设备需要专业咨询？

光生物调节疗法设备需要专业咨询，因为它们需要根据特定疾病和个体情况定制治疗方案，包括光的强度、持续时间和频率等，以确保安全和治疗效果。

光生物调节疗法的剂量-反应曲线是什么样的？

光生物调节疗法的剂量-反应曲线通常是非线性的，存在一个最大效应点，超过这个点，治疗效果不会增加，反而可能减少。

脉冲光在光生物调节疗法中有什么作用？

脉冲光可以产生不同的频率，这可能有助于产生特定的神经认知效果。研究表明，脉冲光可以改善睡眠质量、提高注意力和记忆测试的得分。

如何获取更多关于光生物调节疗法的信息？

可以通过访问medcram.com获取更多关于光生物调节疗法的医学教育信息，或者查看相关的科学研究和数据库，如Vladimir Hekinan整理的包含7000多项研究的电子表格。

光生物调节疗法设备的价格如何？

光生物调节疗法设备的价格不菲，类似于外科手术刀，它们是专业工具，最好在了解其功能和使用方法的专业人士指导下使用。

Outlines

00:00

🌞 光生物调节疗法与人体健康

本段介绍了光生物调节疗法（Photobiomodulation）的概念，这是一种利用光线对人体健康产生积极影响的科学领域。特别提到了光生物调节疗法设备，以及它们在调节激素、增强巨噬细胞活性、降低炎症因子、调节免疫系统、抗菌、细胞保护、抗病毒、细胞信号传导等方面的潜在作用。此外，还提到了光生物调节疗法在治疗长期COVID-19症状方面的潜力。

05:01

🌡️ 光生物调节疗法与COVID-19的关系

本段深入探讨了光生物调节疗法在治疗COVID-19方面的应用，特别是近红外光对改善COVID-19患者的氧化应激和线粒体功能障碍的潜在益处。提到了COVID-19患者体内氧化应激标志物的增加，以及光生物调节疗法如何通过刺激线粒体来改善这些症状。还讨论了光生物调节疗法在改善COVID-19患者的住院时间和肺功能方面的临床试验结果。

10:02

🧠 光生物调节疗法对大脑健康的潜在影响

本段讨论了光生物调节疗法对大脑健康的潜在影响，包括对线粒体功能的改善、减少氧化应激、刺激褪黑激素的产生以及提高能量产生效率。介绍了光生物调节疗法在治疗脑损伤、阿尔茨海默病、抑郁症、焦虑症、长期COVID-19等症状方面的研究进展。同时，还提到了光生物调节疗法设备，如头盔式设备，以及它们在提供脑部治疗方面的潜力。

15:03

🛠️ 光生物调节疗法设备的使用与研究

本段介绍了光生物调节疗法设备，如Neuronics公司的Neur Radiant 1070头盔，以及它们在治疗脑部疾病方面的应用。讨论了设备的使用方式、设置的可定制性以及如何通过专家咨询来优化治疗效果。同时，还提到了光生物调节疗法的剂量反应曲线，以及脉冲光在产生神经认知效应方面的潜在优势。

20:03

🏥 光生物调节疗法的临床应用与未来展望

本段讨论了光生物调节疗法在临床应用中的现状，包括在阿尔茨海默病、脑损伤、抑郁症、焦虑症、长期COVID-19等症状的治疗中的作用。提到了目前尚无FDA批准的光生物调节疗法设备，但有公司如Neuronics和Vlight正在努力获得FDA批准。同时，还提到了光生物调节疗法设备在安全性和有效性方面的研究，以及未来的研究方向。

Keywords

💡光生物调节

光生物调节是指使用光来影响生物体的生理过程，特别是细胞和组织的生化反应。在视频中，光生物调节被用来讨论如何利用特定波长的光，特别是近红外光，来治疗疾病和改善健康。例如，视频中提到光生物调节可以调节激素、增加巨噬细胞活性、减少炎症细胞因子等。

💡近红外光

近红外光是一种光波，波长范围大约在700纳米到1毫米之间。视频中提到，近红外光能够深入人体组织，影响线粒体的功能，从而对健康产生积极影响。近红外光在治疗COVID-19和长期COVID症状中的应用被特别强调。

💡线粒体

线粒体是细胞内的能量工厂，负责产生细胞所需的能量。视频中提到，线粒体功能失调与长期COVID症状有关，而光生物调节能够激活线粒体代谢，促进氧化磷酸化，从而可能有助于修复受损的细胞。

💡氧化应激

氧化应激是指体内氧化剂和抗氧化剂之间的不平衡，导致细胞受到损伤。视频中提到，COVID-19患者体内氧化应激水平升高，这与线粒体功能失调有关。光生物调节被认为可以通过减少氧化应激来改善健康。

💡光疗

光疗是一种使用光来治疗疾病的疗法。在视频中，光疗被用来讨论如何利用光生物调节来治疗COVID-19和其他疾病。例如，视频中提到了使用特定波长的光来改善COVID-19患者的预后。

💡光生物调节疗法设备

光生物调节疗法设备是指用于光生物调节的医疗设备，如视频中提到的头盔式设备，可以发出特定波长的光来治疗大脑。这些设备目前尚未获得FDA批准，但正在研究其在治疗长期COVID症状和其他疾病中的潜力。

💡剂量-反应曲线

剂量-反应曲线描述了药物或治疗的剂量与其效果之间的关系。视频中提到，光生物调节并非剂量越高效果越好，而是存在一个最大效应点，超过这个点效果会递减，这强调了在光生物调节治疗中精确剂量的重要性。

💡脉冲光

脉冲光是指以脉冲形式发射的光，与传统的连续波光不同。视频中提到，脉冲光可以产生独特的神经认知效应，这在光生物调节治疗中是一个重要的考虑因素。

💡褪黑激素

褪黑激素是一种在大脑中的松果体产生的激素，对调节睡眠-觉醒周期至关重要。视频中提到，褪黑激素可以减少氧化应激，并且阳光中的近红外光可能有助于在体内产生褪黑激素，从而对健康产生积极影响。

💡长期COVID

长期COVID是指在COVID-19病毒感染后持续出现的症状，这些症状可能包括疲劳、脑雾和认知功能下降。视频中讨论了光生物调节如何可能帮助改善长期COVID患者的症状，特别是通过改善线粒体功能和减少氧化应激。

Highlights

光生物调节是一种使用光来促进健康的科学领域，正在迅速发展。

光生物调节可以调节激素、增强巨噬细胞活性、减少炎症细胞因子等。

光生物调节的研究文章数量自1980年以来呈指数级增长。

光生物调节对改善健康和治疗某些疾病具有巨大潜力。

近红外光的光生物调节对COVID-19患者可能有益。

COVID-19感染可能导致ACE2受体减少，从而加剧氧化应激。

褪黑激素是减少氧化应激和改善COVID-19患者状况的关键因素。

阳光中的近红外光能深入身体内部，对线粒体产生积极影响。

光生物调节对线粒体功能的影响是其在治疗中发挥最大作用的关键。

光生物调节可能有助于改善长期COVID症状，如疲劳和脑雾。

光生物调节治疗设备尚未获得FDA批准，但正在积极研究和开发中。

光生物调节治疗的剂量反应曲线是非线性的，存在最大效应点。

脉冲光可能产生独特的神经认知效应。

光生物调节治疗设备，如Neuronics和Vlight，正在寻求FDA批准。

光生物调节治疗设备需要专业知识来正确使用，以达到最佳效果。

Neuronics和Vlight的设备提供了可定制的治疗方案，以适应不同疾病的需求。

光生物调节治疗的未来研究可能会揭示更多关于其在治疗长期COVID和其他疾病中的潜力。

Transcripts

[Music]

meg.com welcome to another megr video

we've talked a lot about sunlight and

how the benefits of sunlight can impact

the human body but there is another area

of science which is growing very quickly

termed

photobiomodulation which is the use of

light in health and we're going to talk

about that today we're going to talk

about some of the devices that are being

used specifically for brain brain

photobiomodulation and the potential

that these could have on long covid this

slide that we're starting out with shows

a photobiomodulation therapy device and

a summary of all the things that can

happen the modulation of hormones

increasing maccrage activity decreasing

pro-inflammatory cyto kindes modulation

of the Adaptive immune system and then

there's some other issues like

antimicrobial effects cytoprotective

effects antiviral effects cytotoxic

molecule rupturing the microbial

membrane we have blood vessels and

specific cellular functions and injured

lung tissue cell signaling all of these

things are involved with

photobiomodulation and specifically what

I wanted to show you is this slide here

which is a search of the

photobiomodulation articles that have

been published going back to 1980 the

knowledge and the amount of information

that we're getting in this particular

field of study is growing exponentially

these are the total number of studies

accumulated for the year and for me this

has been an evolution in my

understanding and thinking about light

therapy and how light can affect the

human body we've talked about circadian

rhythm and depression and these are

things that have been welln but we're

now delving into areas that are not

wellknown and are amazing in terms of

the Frontiers that we're learning about

this is an emerging field for those

people that really want to know how to

improve health and some of the

treatments that are coming down and some

of the possible devices this is going to

be a good

video so I'm going to use covid-19 as a

prototype for exactly what the benefits

of near infrared light

photobiomodulation can actually have

this goes way back to a video that we

published on our channel in April of

2020 and it's this understanding that

the ace2 receptor and its loss because

of covid-19 infection can perate the

balance between oxidative molecules and

reducing molecules causing an

exacerbation in reactive oxygen species

and therefore blood clots and hypoxemia

we actually showed that covid-19

increases the amount of Von willbrand

factors secreted into the bloodstream

which causes those clots and you get the

happy hypoxics that we talked about one

of the things that is well known to

mitigate reactive oxygen species is

melatonin and very early on we talked

about about the importance of sleep and

its effect on the immune system and also

on oxidative

stress the findings of oxidative stress

in covid-19 is well documented this was

a paper that was published back in

December of 2021 showing that in

patients admitted to the hospital with

covid-19 they had a reduction in

antioxidants in the cell they had an

increase in the marker of oxidative

stress and also in the marker of

oxidative damage and they showed that

very clearly here for instance this was

a measure of oxidative damage and you

can see across all of the different

years that in those that had covid there

were higher levels of oxidative stress

in the cell and specifically as a result

of

mitochondria and this mitochondrial

dysfunction has come to the surface as

the major way that people develop long

Co you can see here a tweet from Eric

toppel who's been following this and

other articles here mitochondria and

microbi dysfunction in covid-19

pathogenesis here's another article that

was published in science translational

medicine in late August of 2023 core

mitochondrial genes are downregulated

during SARS K2 infection of rodent and

human hosts another one here a study

identifies mitochondrial dysfunction as

the cause of long covid fatigue and so

here we have the intersection of

photobiomodulation exerts its greatest

effects also the intersection of the

cause of one of the newest disabling

diagnoses that we've had in the last

four years which is long

covid this paper was published before

the covid pandemic hit back in 2019 it

was published in melatonin research and

it was in this article that I first

began to understand what was going on

with photobiomodulation and the effect

of natural sunlight which contains a lot

of infrared radiation had on the

mitochondria and the ability of near

infrared light to penetrate deep inside

the body going back to our Paradigm you

can see here very clearly that melatonin

secreted from the pineal gland could be

a mitigating Factor against excessive

reactive oxygen species in covid-19

patients and in SARS cov2 infected cells

but what became apparent to me is that

melatonin from the sun which is produced

on site in the mitochondria could also

have a benefit of that the fact that

sunlight itself through near infrared

radiation could have a benefit in

addition to obviously ultraviolet

radiation producing vitamin D in the

skin this was something that I think was

a paradigm

shift and we produced at least three

videos over the next year the first one

was in January of 22 where we published

light as medicine over 4 million views

now on that video also the case for

sunlight in Co just a few days later in

January 26th of 20122 and finally when

the randomized control trial using near

infrared light in covid-19 from a group

in Brazil was published in a prestigious

Journal we published that about a year

later on January 2nd 2023 which showed

that 940 nanom of infrared radiation for

15 minutes a day 7 days in a row could

actually improve outcomes in covid-19 in

the hospital specifically length of stay

and also pulmonary function testing and

hematological testing and of course with

that my practice changed and added the

ability for covid patients to get

sunlight and we discussed that with a

case where we took a patient outside who

had Co severe enough to require high

flow oxygen at 100% 35 lers and we were

able to get them outside in the sunlight

for about 15 minutes a day every day and

we actually published that finding in

our video that was published on December

6 2023 sunlight for hospitalized covid

many have written me over the last

couple of years in my advocacy of

getting outside and getting sunlight

that you live either in areas where that

doesn't happen or the sun doesn't come

up early enough and you're not able to

get it or you're just not able to get

outside and so there have been many

requests and there have been many

projects I can see in replies to making

their own devices that have near

infrared radiation not every single day

of the week is bright and sunny

sometimes you have overcast clouds and

you can't get out into the Sun and one

of the things that we've noted and

talked about is that near infrared

radiation is blocked by water vapor

because water absorbs in the near

infrared Spectrum specifically at

actually around 940 NM as well as other

areas what this causes of course is our

human tendency to see if we can package

and artificially produce something in

nature first of all I'll just say here

at this point in Venture that I still

believe 100% that the absolute best way

to take advantage of these mechanisms is

to get outside and get natural sunlight

and that is the best way to do it and

it's absolutely free that being said

there are situations where patients

can't get outside it's too cold it's not

enough sun it's too dark they're not

able to physically patients are in the

hospital they're too critically ill they

can't be disconnected from the hospital

there are so many reasons why this could

happen and so people have looked into

this area of

photobiomodulation photo meaning light

bio meaning living cells and modulation

meaning an exertion influence on what

photobiomodulation is specifically is

describing the biochemical reactions

that occur in living cells in response

to light for some of us watching this

video this may be news to us except for

perhaps the retina of the eye we're not

aware of any way in which sunlight or

light affects the human body and what

we're going to find out is that is not

true light does affect the human body in

profound ways and in ways that we're

just starting to understand so just to

be clear about this historically when

you're looking up scientific articles

you're going to see this term

photobiomodulation used in its alternate

terms specifically in bio stimulation

cold or cool laser lowlevel laser

therapy soft laser and low power laser

therapy and these are all terms that

have been used in the past fortunately

in 2015 thanks to Dr Prine areni photo

bio modulation therapy was actually

added to the National Library of

Medicine mesh database entry terms and

so these things will be easier to find

for the most part if you want to

understand a little bit more about the

definition this is how they would say it

in this therapy a light source is placed

near or in contact with the skin

allowing the light energy or photons to

penetrate tissue where it interacts with

chromophores located in cells resulting

in photo physical and photochemical

changes that lead to alterations at the

molecular cellular and tissue levels of

the body light induces a complex chain

of physiological reactions in diseased

and damaged tissues to accelerate wound

healing and tissue regeneration increase

circulation reduce acute inflammation

reduce acute and chronic pain and help

restore normal cellular function

interestingly recent Research indicates

that light can enhance performance in

normal tissues and cells as well and so

this has been a very hot area of

research and as you can see based on

this graph the number of articles that

are coming out are increasing and

probably the number of indications and

devices will be increasing as well so in

my search for understanding about photob

biom modul ation I came across this

database which I'll make available to

you in the link in the description below

this spreadsheet was put together by a

scientist involved in photobiomodulation

who's living in Finland he's also a

dentist his name is Vladimir hekinan

quite an amazing spreadsheet that he's

put together with over 7,000 different

research studies that are categorized

based on the part of the body the type

of trial and the outcomes of course this

is a searchable database and so for

those of you who are really interested

and hardcore in looking at

photobiomodulation I highly recommend

this link it is updated and you can find

a lot of the information on

here in this database you can find

studies like this and case reports for

instance like this a 57-year-old

African-American man with severe

covid-19 pneumonia who responded to

supportive biomodulation therapy first

use of pbmt in covid-19 the wavelengths

that were used here was 88 and 905

nanometers and it was published here in

this article another one here that you

see if you look over here on the right

side of the screen the adjunct low-level

laser therapy in morbidly obese patient

with severe covid-19 pneumonia another

case report again at 808 and 95

nanometers you can see there the name

for this therapy has actually changed

from

pbmt to L llt and that's another reason

why there really needs to be

standardization of this type of therapy

in order for it to be searched but this

database doesn't only include case

studies but also randomized control

trials as well here's a paper that was

published in September of 2020 on the

jamond network and this was a randomized

clinical trial and it was looking at

traumatic brain injury patients to see

whether or not photobiomodulation would

improve outcomes there and here they

used a postconcussion symptoms

questionnaire and the questionnaire

ranked symptoms and so the higher the

number the worse the score was this one

specifically is the rpq 13 and the

authors of this study made their own

device their own helmet which emitted

light at 8810 nanom and it showed that

over 6 months period of time there was a

statistically significant reduction in

the RP Q13 assessment now again this is

traumatic brain injury not in covid-19

patients not brain fog or postco

patients

but this paper postco cognitive deficits

at one year are Global and associated

with elevated brain injury markers and

gry matter volume reduction a national

prospective study in this study they

took 351 previously healthy but

hospitalized long covid subjects and

they match each one of them to at least

eight or more match controls matched for

age sex first language and level of

education and they assessed them 1 to 26

months post discharge to see how they

were and what they found was that that

these postco patients had lower

cognitive scores and it did not

correlate with covid-19 severity and

that recovery took months and was

incomplete as you can see over here in

the graphs the normative graph here is

on the left the middle one that's in red

are the covid patients and then the long

covid patients here you can see in

multicolors things like the

neurofilament light chain or NFL and the

gal fibrillary acidic protein or the

gfap here you can see where were

elevated and were indicative of brain

injury things like too which actually

looks at cognitive impairment was

statistically significantly elevated as

well compared to the normative control

groups and so what we see here in terms

of long Co and brain fog is that it's

not too dissimilar to what we are seeing

in traumatic brain

injury last year we published a video on

our Channel treatment for long Co and we

looked at at photobiomodulation and

sunlight but specifically we looked at

this study looking at a device that was

a helmet that transmits at 170 nanom and

the question that they were asking was

can we get the same effects in the human

body by just doing helmets as we do with

whole body

photobiomodulation and I guess the

question might be why would we expect

the radience of near infrared light into

the brain by wearing a helmet help well

first of all we've Ted talked about that

near infrared light is able to penetrate

through the scalp through the bone

through the cable spinal fluid which

then diffuses it throughout the surface

of the brain and then the crevices

conduct that light deep down into the

surface of the brain where the gray

matter is here's a paper that was

actually just published at the time of

our production of this video which is

March of 2024 showing the trans cranial

photobiomodulation for the brain and its

wide range of clinical applications you

can see here over on the right hand side

of the screen a number of the different

applications that they're talking about

for instance

angiogenesis anti- apotosis cell

migration neuron growth etc etc here's

neurogenesis even lymphatic drainage

which is important in things like

dementia so one of the questions is why

would near infrared light help well

there's been a number of theories that

have looked at this and it has to do

with the mitochondria that in the

neurons and the fact that the

mitochondria is where energy production

occurs and that there's two ways of

energy production there is oxidative

phosphorilation and then there is

glycolysis and it's interesting because

a lot of the effects that are considered

to be relevant here is there are

proteins in the electron transport chain

specifically cytochrome C oxidase which

can interact with light and cause

changes there's also other theories that

near infrared light also stimulates

melatonin production and reduces

oxidative stress and also that near

infrared light makes the water around

the ftpa where energy production occurs

less viscous and therefore more

effective and efficient but let's read

what this article that was just

published this month shows here quote

the activation of mitochondrial

metabolism by photobiomodulation can be

characterized as a switch towards

oxidative phosphorilation and away from

glycolysis this switch has two important

consequences firstly stem cells living

in their hypoxic Niche mainly rely on

glycolysis for their energy requirements

however when their mitochondria are

activated by PBM or photobiomodulation

they must leave their Niche to go in

search of sufficient oxygen to support

oxidative phosphorilation once outside

the niche the stem cells become

progenitor cells and can be influenced

by any cues that might be released from

areas of tissue damage in order to

differentiate into sematic cells where

they can then repair the brain so

basically what it's saying here is this

light signals these progenitor cells

these stem cells if you will to go out

and start actually replacing the damaged

cells that were there

before this is a helmet that is made by

the company neuronic and this is known

as the neur radiant 1070 because it puts

out light at 1070 nanm they did a

head-to-head trial against the entire

bed which is whole body

photobiomodulation which puts out two

different frequencies one at 660 and the

other at 850 and what they wanted to do

was to actually test out objectively to

see whether or not you needed to have a

helmet or a whole bed tissue radiation

so what they looked at here is the data

from these objective data sets and in

the first half you're looking at trans

cranial and in the second half you're

looking at whole body and you can see

that the Improvement in the cognition

score was the same name here again

you're looking at trans cranial and the

Improvement there in the digital symbol

substitution test and you're looking at

whole body here as well and it was about

the same in terms of improvements in

patients who had these cognitive

assessments and this led the authors to

the conclusion that you could get the

same effects with the helmet that you

would get with whole body radiation of

infrared light and if you want more

information on that please watch our

video and we'll put a link in the

description below one of the things

that's also important to understand

about photobiomodulation is normally you

would expect a dose response curve to be

linear so in other words the higher the

dose the more the effect in fact it's

actually basic so in other words there

is a point of maximal impact above which

you actually start to see a diminishing

impact and that was shown very

effectively in this article the basic

dose response in lowlevel light therapy

or

photobiomodulation and so these things

need to be carefully thought out and

there needs to be Advanced planning in

terms of magnitude of the light

therapy the other aspect of

photobiomodulation is this idea that

pulsed light can actually generate

distinct and beneficial neurocognitive

effects this was a paper that was

published in 2023 and they looked at

three different groups at 660 nanm 8 50

nanm over 8 minutes and they had those

that were a control group those that had

continuous wave and those that were

pulsed meaning that there was different

frequencies 40 HZ and 100 HZ to see

whether or not there would be an

improvement what they notice is that

when they pulsed the wave they had

actually better scores in terms of the

Sleep score the cych motor vigilance

tasks and delayed match to sample scores

that were actually improved and the

average power within the gamma band

which is another way of measuring

cognitive ability and so this is

something else that scientists have

Incorporated in photobiomodulation

therapy is the fact that they can be

pulsed I want to say up front that I

have no Financial relationship with

either neuronic or vlight neither

company is paying me to feature any of

their devices in my video I'm just doing

this because there has been a tremendous

demand to comment on what's going on in

terms of devices in terms of long covid

and other diseases that have potentially

photobiomodulation as a treatment so let

me just tell you a little bit about what

the current state of affairs are in

terms of photobiomodulation helmets

their use in Alzheimer's disease brain

injury depression anxiety long covid etc

etc and right now there are no devices

that are FDA approved the two major

companies are neuronic which you see

here and also one that I'll show you in

a little bit called vlight here you can

see on the neuronic website under

research the different diseases and some

of the research that neuronic was

wishing to highlight both neuronic and

vlight are trying to get FDA approval

for their devices and of course the

research that goes into that and the

time and the effort is quite arduous and

my understanding is they could be

anywhere from 2 to 3 years before these

devices get FDA approval and they will

be specific for specific diseases if we

look at that long covid category there

at the neuronic website you'll see some

of the references that they have used

and if we look at their device it's not

inexpensive I consider it like a

surgeon's scalpel Just Like a Surgeon

scalpel it is a tool that is used but is

best used when under the control of

someone who is knowledgeable and

understands what that device can do as

I'll show you here in a little bit this

device is not something that you just

put on your head and flip a button there

is a number of inputs and there are

variables that you can input to have the

desired effect you can see here adding a

3-month consultation in how to use this

device is actually going to be very

helpful this is the other company vlight

and they have a similar appearance but I

believe this one is slightly different

in that there is a nasal probe as

well back to the new radiant neuronic

did send me a neuro radiant 1070 and

they gave that to me for free to try out

and I will be sending it back to them

after I'm done with it so as you can see

here this is simply a helmet that plugs

in in and it's got light emitting

devices on the inside that irradiates

the outside of the skull and penetrates

through you can put different sized pads

on there and you can see as it fits

pretty easily on your head however this

controller has a number of different

inputs and this is really where I think

the genius of this type of a device has

come in is they've made it so

customizable that if protocols down the

line are found for specific types of

diseases they can very easily be entered

here as you can see there is generalized

settings like peace focus and energize

and these have different settings and

pulses and durations but there's also a

customizable program where you can input

specifically what part of the helmet is

activated and for how long at what

intensity and I think this is important

in terms of being upfront with them in

terms of consultation so they have

experts who are knowledgeable about the

types of settings that they would

require for different types of

conditions and again that's why I would

say this is very similar to a scalpel so

this is a tool that is used and the

outcomes will be based on consultation

with the experts that understand and

know how this type of a device would be

used for your particular

situation I did notice on their website

that they are starting a clinical trial

and that they are looking for people to

enter into that clinical trial so they

can do further research and submit those

to the FDA for approval these are are

some of the eligibility criteria 50 to

75 years of age located in the United

States have mild cognitive impairment

have a computer and a smartphone have a

caregiver or family member willing to

help and willing to drive for up to 20

mil to obtain two EEG tests one at the

beginning and one at the end of the

study in the sake of equal time here we

have vlight and they also have a similar

device as we mentioned if we ask on

their website whether or not this is FDA

approved there is a message that comes

up saying that no it is not FDA approved

the FDA have categorized our devices as

lowrisk General Wellness devices in

accordance to the fda's draft on General

wellness policy on lowrisk devices dated

January 20 2015 all Vite devices have

been independently TUV certified as safe

for Consumer use and I believe that is a

German or European Standard as this

company is based in Europe so I hope

this video has been informative you may

not have gotten specific information

about the conditions that you have but I

believe that looking at that Excel

spreadsheet which we'll give the link to

and understanding more about the

condition that you're specifically

concerned about will give you more

information in terms of that I will

reiterate again I think that

photobiomodulation therapy is a type of

therapy that is a tool the way that that

tool is used will determine the outcome

when that tool is implemented please

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