Exercise volume and health: minimum dose, optimal dose, and can too much exercise shorten lifespan?
Summary
TLDRIn this podcast, the hosts delve into the relationship between exercise and health, particularly endurance sports like running, cycling, and swimming. They discuss the idea that while exercise is crucial for health, there may be a point of diminishing returns where over-exercising could become counterproductive. The conversation touches on the 'J-shaped' curve of exercise longevity, where too much exercise might increase mortality rates due to factors like cardiac dysrhythmia. The hosts also emphasize the importance of understanding one's limits and the role of discomfort in exercise. They stress that for most people, the goal should be to increase physical activity rather than worry about over-exercising, and that a balanced approach to exercise, including strength training and varying intensities, is key for overall health and longevity.
Takeaways
- 🏃♂️ The purpose of endurance sports like running, cycling, and swimming is to enhance speed and endurance.
- 👨👩👧👦 Most people are not competing anymore, yet endurance-based exercise remains a crucial component of overall health.
- 🚫 The term 'cardio exercise' is disliked, but it's acknowledged that it's important for health.
- 🤔 The discussion explores if there's a point where exercise becomes counterproductive and the specific benefits for metabolism and disease prevention.
- 🚫 The concept of 'over-exercising' is examined, with a focus on the potential negative effects on health, including cardiac issues.
- 🔍 There's a debate on the optimal amount of exercise, with some suggesting a J-shaped curve where too much exercise can lead to increased mortality.
- 🏥 Studies like the Copenhagen and Cooper Clinic ones are critiqued for their methodologies, which may skew results on the benefits of exercise.
- 🏋️♂️ Strength training is highlighted as an important aspect of a well-rounded fitness routine, often overlooked in favor of endurance activities.
- 🤷♂️ For most people, the concern isn't over-exercising but rather the lack of exercise, with a focus on getting more people to be active.
- 🧘♂️ Exercise, particularly endurance training, can serve social and mental health purposes beyond physical benefits.
Q & A
What is the general consensus on the importance of endurance-based exercise for health?
-Endurance-based exercise, such as running, cycling, and swimming, is considered an important pillar of health. It is crucial for building endurance and speed, which are key aspects of fitness. Even for those who are no longer competing, it remains significant for overall health.
How does the perception of discomfort during exercise affect one's exercise routine?
-Many people interpret distress signals during exercise, such as panting or muscle fatigue, as signs that they are reaching their physical limits. Understanding that these discomforts are not harmful but rather indicators of exertion can help individuals push through and continue exercising.
What is the J-shaped curve theory regarding exercise and longevity?
-The J-shaped curve theory suggests that there is an optimal amount of exercise for longevity. At low levels of exercise, mortality rates are high, but they decrease as exercise increases. However, beyond a certain point, increasing exercise volume may lead to a slight increase in mortality, possibly due to overexertion and associated health risks.
What is the minimum effective dose of exercise for health benefits?
-According to some studies, even a small amount of exercise, such as 5 to 10 minutes a day, can provide significant health benefits. However, this is a starting point, and individuals, especially those returning to exercise after a long hiatus, may benefit from gradually increasing this amount.
How does the type of exercise influence the potential benefits and risks?
-The type of exercise can greatly influence its benefits and potential risks. For instance, marathon training may not be the best for longevity due to its intense nature, while a more balanced approach, including strength training and varying intensities, might be more beneficial.
What role does the social aspect play in endurance sports?
-Endurance sports often have a significant social component. For many, activities like running or cycling are not just about physical exercise but also about social interaction and stress relief, which can contribute positively to mental health and overall well-being.
What are the potential downsides of excessive endurance training?
-Excessive endurance training can lead to issues like cardiac dysrhythmia, aerosis, endothelial damage, and fibrosis. It's important to balance training with rest and other forms of exercise to mitigate these risks.
How does the concept of 'opportunity cost' apply to exercise routines?
-The concept of 'opportunity cost' in exercise routines refers to the potential benefits foregone by focusing on one type of exercise, such as marathon training, at the expense of other activities that could contribute more to overall health and longevity.
What is the significance of the statistical adjustments made in studies regarding exercise and mortality?
-Statistical adjustments in studies can significantly affect the conclusions drawn about exercise and mortality. It's crucial to ensure that these adjustments do not unfairly penalize or advantage certain groups, as this can lead to misleading results, such as the appearance or disappearance of the J-curve.
Why might the J-curve hypothesis be controversial in the context of exercise and health?
-The J-curve hypothesis is controversial because it suggests that too much exercise might be detrimental to health. However, the methodology used in some studies, particularly regarding the statistical adjustments made, has been questioned, leading to debates about the validity of the hypothesis.
How should individuals approach exercise if their goal is to optimize their health span?
-If the goal is to optimize health span, individuals should consider a well-rounded exercise routine that includes strength training, flexibility exercises, and varying intensities. They should also focus on activities they enjoy to ensure sustained engagement and consider the social and mental health benefits of their chosen exercises.
Outlines
🏃♂️ The Importance of Exercise in Health and Endurance Sports
The paragraph delves into the significance of exercise, particularly endurance sports like running, cycling, and swimming, in relation to health. It emphasizes the dual goals of speed and endurance in sports and acknowledges the shift in focus from competition to health as people age. The discussion touches on the concept of 'cardio exercise' and its importance as a health pillar. It raises questions about the potential counterproductive effects of excessive exercise and the specific benefits of exercise for energy efficiency and metabolism in combating disease. The speaker encourages a scientific and personal reflection on these topics, hinting at a broader conversation to come.
🚴♂️ Exercise Intensity and Its Impact on Health
This section explores the idea that while exercise is crucial for health, there might be a point where it becomes counterproductive. It discusses the 'J-shaped' curve of exercise longevity, suggesting that a certain volume of exercise is optimal, but beyond that, there might be increased mortality risks, such as cardiac dysrhythmia. The paragraph also introduces a contrasting viewpoint that exercise benefits may increase monotonically with no negative uptick. The speaker reflects on their own exercise habits, suggesting that while they may not be at the extreme end of the curve, understanding the relationship between exercise volume and health is complex and personal.
🏋️♂️ Balancing Exercise for Health vs. Performance
The discussion here centers on the practical aspects of exercise, particularly the distinction between exercising for health and for performance. It challenges the notion of a J-shaped curve relating to exercise volume and mortality, citing issues with statistical adjustments in studies that claim such a relationship. The speaker argues that the health benefits of exercise are in helping regulate factors like blood pressure and blood sugar, and adjusting for these in studies may be misleading. The paragraph concludes with a focus on the importance of exercise variety and the potential downsides of excessive endurance training, suggesting that a well-rounded approach to exercise is more beneficial than extreme training for longevity.
🤸♂️ The Role of Exercise in a Well-Rounded Health Portfolio
This paragraph emphasizes the importance of a diverse exercise routine for longevity, critiquing the idea that intense training for specific sports like marathons or the Tour de France is optimal for health. It points out that such training can lead to anemia, osteoporosis, and poor posture, which are not conducive to a long and healthy life. The speaker advocates for a balanced approach that includes strength training, stability exercises, and varying workout intensities to work different energy systems. The paragraph also touches on the social and pleasurable aspects of exercise, suggesting that for many, the motivation for high-mileage training is not health optimization but competition or personal fulfillment.
🎵 The Multifaceted Benefits of Running Beyond Physical Health
The final paragraph of the transcript is a brief musical interlude, suggesting a pause or transition in the conversation. It does not contain any spoken dialogue or information to summarize.
Mindmap
Keywords
💡Endurance Sports
💡Cardio Exercise
💡Exercise Barriers
💡Physically Active
💡Exercise Volume
💡Metabolic Syndrome
💡Minimum Effective Dose
💡Injury Prevention
💡Statistical Adjustment
💡Longevity
💡Social Element
Highlights
The discussion emphasizes the importance of endurance sports for health, even for those who are no longer competing.
Endurance-based exercise is acknowledged as a crucial pillar of health, despite the participants not being professional athletes.
The conversation delves into the concept that exercise can become counterproductive beyond a certain point.
The potential for exercise to be counterproductive is linked to energetics, efficiency with metabolism, and disease resistance.
The idea that exercise should not be feared but understood as a way to gauge one's physical limits is presented.
The conversation challenges the notion that discomfort during exercise is a negative signal.
A J-shaped curve is introduced to discuss the relationship between exercise volume and mortality rates.
The debate over whether there is a point of diminishing returns with increased exercise is explored.
The discussion points out that for most people, the goal should be to increase exercise rather than worry about over-exercising.
The importance of understanding the health benefits of a modest amount of exercise is highlighted.
The Cooper Clinic study's findings on the minimum effective dose of exercise are mentioned.
The conversation suggests that for some, increasing strength training might be more beneficial than adding more mileage to their running.
The potential downsides of excessive endurance training, such as cardiac dysrhythmia, are discussed.
The practical issue of whether people are exercising too much is addressed, with a focus on the need for a well-rounded exercise routine.
The discussion argues against the idea that everyone should aim to run a marathon for health optimization.
The social and pleasurable aspects of endurance sports are recognized as important factors that contribute to their value.
The conversation concludes that the focus should be on the quality of exercise rather than the quantity for most people.
The importance of not penalizing exercisers for the health benefits they've gained from exercising is emphasized.
Transcripts
where do you think this fits
into health so there's I mean this is
clearly uh an important topic when we're
talking about sports right when we're
talking about Endurance Sports like you
know running and cycling and swimming
the purpose of the sport is to be fast
is to have endurance and speed at that
right combination um many of the people
listening to this podcast are no longer
competing you know you're still
competing but most people aren't I don't
compete at anything anymore
um but I hate the term but quote unquote
cardio exercise or endurance-based
exercise we would still agree is still
an important pillar of health
so how do you how do you think about
that and and more importantly how do you
think about what you've studied um
applying to health and and one of the
things I want to talk about because it's
so interesting of course is at some
point does exercise become
counterproductive and maybe even what
are the benefits specifically uh you
know for example energetics uh
efficiency with metabolism and how that
can fight disease so uh in any way you
want to start that discussion like how
how do you start to think about it uh
both scientifically and even
personally yeah so that's a big bite to
chew on that's you you've mapped out the
next uh three hours of our conversation
yes um so one thing I would say is I
mean look I don't want to oversell it
and say you must understand you know
your your absolute limits in order to be
healthy
but I I do think in terms
of if we think about the barriers to
exercise the barriers to being
Physically Active I think for a lot of
people
um there's a if you interpret the
distress signals you feel when you start
exercising as signs that your body is
reaching its limit that's a very
distressing thing you you you know if
you're like I'm going to start an
exercise program I'm going to start
brisk walking I'm going to start running
and you feel you're panting you're out
of breath your legs are burning you're
like I'm going to die and you stop and
so I think understanding that
these it's not so much about how to
change your limits but understanding
what those limits represent
understanding that they are
not signs that you're going to die these
are just this is just information this
is and because I would say and I I
haven't thought this through maybe it's
not true but I would say off top of my
head any meaningful form of exercise
that's going to do you substantial
amounts of good is going to involve
dealing with discomfort uh in in in one
form or another and if you can get to a
place where you understand that the
feelings of discomfort are not signs
that something is going wrong with your
body but they are just information they
are telling you where you are on the
road to reaching your limits and you
don't have to go to your limits but you
also don't have to stop you're allowed
to just interpret that as information
and say okay understood I'm out of
breath but I can keep going so I
think to me at least that that's a
useful insight to take to take from this
now you know we could we can get deeper
then into you you know you've raised
some some very interesting and
controversial questions about you know
how much exercise is good what kind of
exercise do we need to do I don't know
where you want to start with that well
let's because we don't have three hours
although I I
mean when we meet in person and and and
share a meal we we certainly will take
those three hours but I let's start with
um two opposing points of view with
respect to exercise so one point of view
says the exercise longevity curve is
j-shaped so at at at the you know far
end of the spectrum uh no exercise is
you know a really bad thing for
mortality um as you increase exercise
mortality improves improves improves
improves improves improves and then it
kind of gets to your best all cause
mortality and if you continue to
increase exercising Beyond a certain
volume this is generally discussed in
volume of exercise you actually see a
little uptick in mortality suggesting
that once you go beyond a certain point
again I want to stress this is in volume
of exercise you don't get any more
benefit and you may actually have more
harm and a lot of times this is harm
that comes in the form of cardiac
dysrhythmia um could be even aerosis
through endothelial damage fibrosis
things like that there's another body of
literature that that says no it's more
or less a monotonically improving curve
and again we all agree that at one end
of the spectrum uh having you know
really poor cardiovascular fitness again
we could measure this in V2 Max or
something like that uh as that improves
and you get fitter and fitter and fitter
and fitter all cause mortality goes
lower and lower and lower and there is
no J to that curve um how do you think
about reconciling those and I I want to
point out at the outset this is a
discussion that only really impacts like
1% of the population because 99% of the
population are on the side of the curve
where they could always benefit from
exercising more but you know you for
example might be one of those people
who's in the 1% where I don't know
what's your weekly mileage right
now I I I fortunately it's only probably
about 20 miles so so even uh even James
o'keef would would would give me a pass
yeah yeah yeah so um so walk me through
how you think about that because I have
to be honest with you um I'm I've seen
examples of you know those athletes who
go a little bit too far who probably
have a genetic susceptibility to dis
rythmia and then they go on and get
these
dysrhythmias um but at the same time
they're few and far in between so I
don't I don't I'm still a bit on the
fence about this one again just purely
from an intellectual standpoint I don't
think it applies to me anymore it
probably did at some
point so it's it's it's it's a good
question it's an important one and
there's a a couple a few things I want
to say first I'm a runner right so so
take take what I say understand where
I'm coming from I'm also a human like I
don't want to die so I'm I I try to look
at this data as imp as dispassionately
as possible so but but I I obviously I
my kneejerk reaction is like let's find
holes in this data that suggest running
is bad so I get that on the
table second there's no doubt that
there's a reverse J curve if you try to
run 20 20 hours a day it's not going to
be good for you so like it's nothing is
good for you if you push it far enough
so the real question is where do the
extremes or where does the the uptick
happen
um third thing I want to say is the this
this the data on this this showing that
you know you do a little bit you get
some benefits and the more you do it it
gets worse and worse one really
interesting thing that came out of that
were a few studies in about eight years
ago that that showed that is that
actually the the dose you need to get
most of the health benefits is very
small and I do think that's an important
message you do not need to train or for
or run marathons in order to be
optimally healthy at least to within the
you know the 90% or whatever you're
going to get most of what you get from a
very modest amount of exercise and so
that's a great message so okay now then
can you quantify that by the way in
terms of in terms of running let's let's
put some numbers to that if you're
talking about a person who maybe was
active in high school and college but
you know they're they're 10 or 20 years
out of that they've been caught up in
the challenges of starting their career
starting their family Etc they wake up
they're 40 years old and their waist is
5 in bigger they've got metabolic
syndrome they're not in Dire Straits
it's not like they're going to die in
the next 10 years but they've got the
message which says Hey the one thing
that is really missing is your
exercise what what would you say if they
SC to you and said Alex just tell me the
minimum effective dose I don't want to
run any weekend races I like running I
used to love it uh or rowing or whatever
their activity is how how many hours or
how many miles do I need to do a week to
just get the benef some of the you know
80% of the benefits with 20% of the
efforts yeah so so the the Cooper Clinic
study which was like 50,000 people or so
uh that came out four or five years ago
they're
number was 5 to 10 minutes a
day I don't fully believe that but that
that was their number so they're talk
you're talking like an hour a week um I
and and that's just you know going out
for a run I personally we maybe we can
get into this and that that's not my
definition of an optimal exercise
routine I would include some
high-intensity stuff I you know strength
is another thing but um so they're
there's making some claims about a very
very low minimum effective dose
personally I would say so I I said like
I said I'm probably running about 20 mil
a week right now which is 6 days a week
you know half an hour with a couple of
hard days I think that's on the to me
that's on the low end of of I I think I
would be healthier if I did more at this
point um and it's just you think you you
would actually be healthier I know you'd
be a better Runner but would you be a
healthier would you would you live
longer I think I think I would now I
think if I if I had to the first thing I
would do if you know if I was if I had
instant motiv
powder that I was going to dust on
myself I would get I would up my
strength R my my strength training
routine that would be the first thing I
do if longevity was my first priority oh
I'm sorry I misunderstood so you
wouldn't necessarily run more you would
take extra time and add it in the weight
room or do something else no I would run
more like if if if I was prioritizing I
would prioritize strength first but I
think if I could also if I also change
you know I I think for me because
because I'm come from a background where
I'm already I'm used to running 20 mil a
week doesn't stress me very much you
know I it it just slows down my decline
I I think I could benefit from let's say
one long longer run a week or something
like that this the gut feel let's not
you know I don't want to this is not
supported by anything other than my gut
but so the 5 to 10 minutes a day it
might be it's definitely the right place
to start if you're the 45-year-old you
know sedentary you know getting back
into it but I think you you might want
to push something a little higher a
little higher than that um or or
certainly if you're doing if you're
doing 60 Minutes a week I wouldn't do it
in 5 to 10 minute chunks I would do some
20 minute chunks or whatever and what do
we know about injury prevention in that
person that probably they're going to
get injured because they're G to because
they're going to find that they're no
matter how metabolically unfit they are
they're probably going to find that they
gain metabolic Fitness more quickly than
they gain uh you know tendon stiffness
and and and muscle strength and things
like that so in a sense that's a even
more reason to to sort of take that
guideline seriously I mean I'm talking
about running which because I love you
you're less likely to get injured if you
go cycling or something like that that's
obviously there's other other ways of
mitigating the the injury thing but yeah
from
so but let me let me just cast some
doubt on the on the j-shape thing the
there there were two main studies on
which this whole J curve hypothesis was
founded one was the Copenhagen uh study
and and one was the Cooper Clinic study
the Copenhagen study initially it came
out saying running is great and more
running is better and then they
reanalyzed it uh with a new co-author
and and they concluded that running too
much or too fast was bad that was based
on uh there were two deaths in the in
the group that ran too fast like this is
not the confidence interval was
essentially infinite
like but there's a more serious problem
and that and it's one that affects the
Cooper Clinic data too which is is that
when you're when you have a big study of
50,000 people who were just randomly
selected they're not all the same they
all have different characteristics so
you have to find some way of adjusting
for various characteristics um and
without going too far down the rabbit
hole
basically they statistically adjusted
initially at least for things like uh
cholesterol levels weight uh blood sugar
levels blood pressure because you want
to you know it's meaningless if you
compare like we had this you know the
non-runners died sooner than the runners
but they were also 20 pounds heavier and
had all these other risk factors so you
want to equalize it um but there's a
problem that if you equalize it you're
bit you're you're essentially saying
well what are the health benefits of
exercise if you don't do any exercise
because the health benefits are of
exercise are precisely in helping you
regulate things like blood pressure and
blood sugar and controversially but I
would say weight also um
so essentially I mean to me that was
statistical misconduct like that that so
you're you're saying if you take the the
people who exercise and you subtract you
basically penalize them for having lower
weight better lipids better blood sugar
better blood preure so you you bring
them in line so that they're just as
overweight and just have all the other R
risk factors then you see this J curve
now when they actually published the
data in a peer- reviewed Journal two
years after it was presented they had
eliminated that that statistical method
and the J curve had disappeared you no
longer Saw the J curve
now there you know I don't I don't want
to just dismiss and say therefore
there's nothing to see I'm just saying
that if we're talking about where the
curve
happens if you do that kind of
statistical adjustment which is the
equivalent of saying like I want to know
whether smoking causes cancer but I
can't compare the smokers and nonsmokers
because the smokers have more lung
cancer so let's artificially equalize it
and pretend that the smokers just have
just as much cancer that I mean that you
can't basically in statistical terms you
can't adjust for a variable a mediating
variable a variable that's affected by
the thing you're trying to
measure so sorry as you can tell this is
this is a topic I get excited no it is
and I've read what you've written about
it which is why I wanted to bring it up
I have a slightly different take on it
which is less about everything you've
said and more of the Practical issue
because the Practical issue is the one I
get asked about a lot which is am I
exercising too much right this is the
person asking the question and so again
let's pause it for a moment that 99% of
people are not exercising too much and
don't even possess the fortitude to
exercise too much right they don't the
the the pain tolerance isn't there the
obsession with exercise isn't there so
for for 99% of people we'd like to get
them to exercise more or stay the same
we're dealing with 1% of the population
many of whom I know and one of whom I
used to be um that we kind of the hyper
exercisers here's the bigger point I
would make it's probably less relevant
whether or not they're spending too many
hours cycling swimming running Etc
usually people in this sense it's not
the number of hours they're spending
it's the portfolio allocation of how
they're spending it that's the bigger
problem it's that they're not well
rounded and they're not actually in
pursuit of longevity so the reality of
it is is training for the tour to France
going to increase your longevity
absolutely not no way like those guys
finish the tour who are anemic
osteopenic their upper bodies are
emaciated their posture is horrible
there's nothing about that that is
setting you up to be an octogenarian
that kicks ass nothing whatsoever so
they physiologic Marvels but their
health span sucks right so that's using
that as an extreme what do how would we
extrapolate that to The 40-Year-Old who
just can't hang up the dreams of being a
professional athlete who's out there you
know running or riding or doing all of
that stuff non-stop but at the expense
of maybe not doing some Pilates to work
on core strength I hate the term but you
know what just for people to understand
what I'm saying like not working on
stability not spending any time in the
weight room really working on strength
not varying the intensity of their
workouts to work different Energy
Systems so to me that's the bigger issue
with people who are exercising too much
it's probably not that they're at the
little tip of a j that may or may not
exist it's that they're squandering
their time it's like having all of this
money but you're invested you have a
lousy
portfolio yeah okay I I I agree with a
lot of that one thing I'll say is is the
important question you're you're you're
implicitly asking there is what's your
goal right like what what are you
training for well that's I said
longevity this was all predicated
towards living a longer healthier life
and meaning and so not winning races or
whatever I I would 100% agree if if
someone CES comes to me and says I you
know
I want to optimize my exercise program
for longevity like I said before there's
no there's no way I would tell them you
should be run training for a marathon
that's not because I think training for
a marathon is bad but like you said it's
an opportunity cost of of other things
you could be doing that a lot of other
things you could be doing that would
probably work better that so I I think
it's really important to disabuse people
of the notion that um in order to
optimize your health you should run a
marathon but I where I Bridle with this
whole this sort of the the media
coverage of the that that stream of
research is that that's different from
saying that people who are training for
a marathon because they want to run a
marathon or because they want to run a
marathon as fast as possible
should should stop because that's bad so
it's like of the of the of the category
of people who have unhealthy behaviors
who we should intervene to save them
from themselves it's like like people
who are training for a marathon to me
are not even close to being in the same
category as people like me who are
sitting at a desk for for eight hours a
day or whatever the case may be so it's
like there's a difference between
optimizing and avoiding like serious
problems and and and I the one other
thing I should acknowledge is and you
you alluded to it is there are other
issue potential issues with with lots of
endurance training and arhythmia is one
of them and there's there's better
evidence that that's that's a real thing
um so you know like there may be a price
uh there may be downsides to to to
training really hard on
balance overall I would say I don't I
don't lie awake at night worrying about
people who are running 50 miles a week
yeah you're right uh you you should
worry far more about people who are
eating poorly smoking who are stressed
out of their minds and don't have coping
mechanisms for them yeah there there are
there's a there there's there's not many
people that you should be worrying about
more or less rather yeah and and and if
I think of the people I know who who
let's say run the equivalent of 50 miles
a week or more I I I can't think of any
of them who would say I'm doing this
because I think this is what I need in
order to optimize my my health span or
lifespan that you know they obviously
hope it's healthy but I think if you're
if you're training for a marathon most
of them are doing it for for competition
or not you know self-c competition in a
way and and it sort of reminds me of
something you know you discussed this a
little bit I think in in your
conversation with James O'Keefe the the
sort of what's great about t tennis and
badminton and and volleyball or whatever
what's the social social element of it
and I think sure on average running is a
solitary sport but for me it's it's my
primary social outlet it's where I meet
my friends it's where I uh you know get
together and and catch up on the week on
an easy run so it's like I think that's
true for a lot of people who once you
get into that 50 miles a week not for
everyone but for for a lot of people
it's a social element it's it's
pleasurable it's a stress reliever so it
it goes beyond the the you know if
you're if you take that away um I'm not
sure it it Nets out as positive
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