Cara Kerja Enzim

Summary

In this video, Ilham Firdaus explains how enzymes work, focusing on two key theories: the lock and key theory and the induced fit theory. The lock and key theory, proposed by Emil, suggests that enzymes have a specific active site that perfectly fits the substrate, like a lock and key. In contrast, the induced fit theory, put forward by Daniel Fashland, describes enzymes as having a flexible active site that adjusts to fit the substrate. The video highlights these theories with examples to demonstrate how enzymes facilitate biochemical reactions.

Takeaways

• 😀 The video is about explaining how enzymes work.
• 😀 The speaker introduces two main theories: the lock and key theory and the induced fit theory.
• 😀 The lock and key theory was proposed by Emil Fischer.
• 😀 According to the lock and key theory, enzymes have a specific active site that fits perfectly with a substrate.
• 😀 An example of the lock and key theory is the perfect compatibility between the enzyme’s active site and the substrate.
• 😀 The induced fit theory was proposed by Daniel Koshland.
• 😀 The induced fit theory states that enzymes have a flexible active site that adjusts to fit the substrate.
• 😀 The active site of the enzyme and the substrate do not perfectly match at first in the induced fit theory.
• 😀 In the induced fit theory, the enzyme’s active site changes shape to fit the substrate.
• 😀 The speaker apologizes for any mistakes and thanks the viewers for watching.

Q & A

What is the main topic of the video?

The video explains how enzymes work, specifically discussing two theories: the lock-and-key theory and the induced fit theory.

Who proposed the lock-and-key theory of enzyme action?

The lock-and-key theory was proposed by Emil Fischer.

What does the lock-and-key theory suggest about enzyme action?

The lock-and-key theory suggests that enzymes have a specific active site that precisely fits a substrate, allowing them to bind together perfectly, much like a key fitting into a lock.

What is the key concept behind the induced fit theory of enzyme action?

The induced fit theory suggests that enzymes have a flexible active site that adjusts its shape to fit the substrate, allowing for a more dynamic interaction between the enzyme and the substrate.

Who proposed the induced fit theory?

The induced fit theory was proposed by Daniel Koshland.

How does the active site of the enzyme change according to the induced fit theory?

According to the induced fit theory, the active site of the enzyme changes its shape to accommodate the substrate, allowing the enzyme and substrate to bind more effectively.

How do the lock-and-key and induced fit theories differ?

The lock-and-key theory suggests a rigid, precise fit between the enzyme and substrate, whereas the induced fit theory proposes that the enzyme’s active site is flexible and adjusts to better fit the substrate.

What is an example of how the lock-and-key theory works?

In the lock-and-key theory, the active site of the enzyme and the substrate fit together perfectly, like a key fitting into a lock, ensuring a precise interaction between the two.

What does the induced fit theory suggest about the enzyme-substrate interaction?

The induced fit theory suggests that the enzyme's active site is not a perfect fit for the substrate initially but adjusts its shape to fit the substrate better during the binding process.

What can we conclude about enzyme flexibility from the two theories discussed?

The lock-and-key theory implies a rigid interaction between enzyme and substrate, while the induced fit theory highlights the enzyme’s flexibility in adapting to the substrate's shape.