Video Searching Methodologies for Credible Drug Information

Summary

This video outlines a practical pharmacology session focusing on drug information. Students will learn how to gather, analyze, and report on drug-related information using various resources, including MIMS, WHO, and Drugs.com. The session covers key aspects such as identifying active ingredients, understanding drug indications, costs, drug classifications, and potential interactions. Additionally, students will complete assignments on drug monographs, report adverse drug reactions, and evaluate drug interactions. Real-world scenarios involving patients with conditions like hypertension and hypercholesterolemia are used to apply these skills. The practical session helps students improve their ability to report and understand drug-related information and interactions.

Takeaways

• 😀 The practical session focuses on developing skills related to drug information, including creating drug monographs and reporting adverse drug reactions.
• 😀 The practical scenario involves a 55-year-old male patient with severe hypertension, hypercholesterolemia, and a history of myocardial infarction, who is prescribed five medications.
• 😀 Key learning points include identifying active ingredients in medications, understanding their indications, and understanding the cost and classification of the drugs prescribed.
• 😀 The MIMS.com website is used to find active compounds in drugs, along with their indications and safety for pregnant women.
• 😀 Drug safety during pregnancy is categorized into levels A, B, C, D, and X, with Category D indicating risk to the fetus but potential benefit in certain cases.
• 😀 Drug costs can be determined using MIMS.com or the Indonesian E-Katalog from LKPP.go.id, providing pricing details for drugs under BPJS insurance.
• 😀 To understand drug classification, the WHO's ATC/DDD Index is used, which categorizes drugs by anatomical, therapeutic, and chemical classifications.
• 😀 The interaction checker on Drugs.com allows users to check potential drug interactions, which are classified as major, moderate, minor, or unknown based on their clinical significance.
• 😀 Major interactions should be avoided due to their high clinical risk, while moderate and minor interactions may be acceptable under specific circumstances.
• 😀 Pharmacological profiles, including pharmacokinetics, dynamics, and mechanism of action, can be accessed through reliable resources like Drugs.com and FDA prescribing information.
• 😀 The final tasks involve completing a drug monograph assignment, analyzing potential drug interactions, and reporting adverse drug reactions using specific forms and algorithms (e.g., Naranjo Algorithm).

Q & A

What is the purpose of the practical session described in the video?

The purpose of the practical session is to develop skills in drug information, including understanding the active compounds in medications, developing drug monographs, and learning how to report adverse drug reactions.

What kind of case is used for the practical session?

The case used involves a 55-year-old male patient with severe hypertension and hypercholesterolemia, who has recently been treated for a myocardial infarction. A prescription with five medications is provided to this patient.

What are the five medications mentioned in the prescription?

The five medications mentioned in the prescription are Farmoten (25 mg), Lodos (2.5 mg), Tromboaspiled (80 mg), Plavix (75 mg), and Merifas (10 mg).

Why is it important to know the active compounds in the prescribed medications?

Knowing the active compounds helps understand what substances are present in the medication, their indications, and potential interactions or side effects, providing a better foundation for pharmaceutical practices.

Which website is recommended for looking up drug information, including active compounds and prices?

The recommended website for looking up drug information is MIMS (mims.com), which provides details about active compounds, drug prices, and safety categories for use during pregnancy.

What is the significance of the safety categories for drug use during pregnancy?

The safety categories (A, B, C, D, and X) indicate the potential risks a drug poses to the fetus during pregnancy. Category A is the safest, while Category X is contraindicated for use in pregnant women.

What is the purpose of using the WHO's ATC classification system?

The WHO's ATC (Anatomical Therapeutic Chemical) classification system is used to classify drugs based on their therapeutic use and chemical properties. It helps categorize medications by their action and target system.

How can you check for drug interactions in the prescribed medications?

Drug interactions can be checked using the 'Interaction Checker' tool on websites like drugs.com. This tool allows you to input the generic names of medications to see if there are any significant interactions between them.

What are the different levels of drug interaction severity?

The severity levels of drug interactions are: Major (clinically significant and should be avoided), Moderate (clinically significant but may be used in specific cases), Minor (minimal clinical significance), and Unspecified (unknown or not documented).

What should be done if an adverse drug reaction is reported during the practical session?

If an adverse drug reaction is reported, the reaction should be documented using a 'yellow form,' which is submitted to regulatory bodies like the National Food and Drug Monitoring Agency (Badan POM). This process ensures that the adverse event is officially recognized and tracked.