缺叶酸,类似辐射伤害!自然疗法,柏格医生dr berg
Summary
TLDR维生素B9(叶酸)缺乏可能导致DNA损伤,进而引发癌症。叶酸是帮助制造RNA和DNA的辅酶,对细胞功能至关重要。叶酸不足不仅会导致DNA损伤,还会影响DNA修复过程。教授Bruce Ames的研究揭示了叶酸缺乏与X射线辐射造成的损伤相似。叶酸的合成形式(叶酸酸)广泛用于孕妇的产前维生素中,有助于预防神经管缺陷,但过量摄入可能存在风险,尤其是携带MTHFR基因突变的人群。这种基因突变会影响叶酸酸转化为活性形式的能力,导致未代谢的叶酸酸积累,可能增加患癌症和自闭症的风险。B9(叶酸)还与新癌细胞的生成有关,但只有在过量摄入时才会出现问题。解决这一问题的方法是摄入不需要转化的B9形式,如甲基叶酸。此外,叶酸过量还可能掩盖B12缺乏,导致同型半胱氨酸水平升高,增加心脏病和中风的风险。建议通过食用富含天然叶酸的食物,如深色绿叶蔬菜,来维持健康。
Takeaways
- 🚨 叶酸(维生素B9)缺乏可能导致DNA损伤,进而引发癌症。
- 🌟 叶酸是一种辅酶,帮助制造RNA和DNA,对细胞功能至关重要。
- 🧬 DNA复制过程类似于高速旋转的拉链,涉及三维结构的精确复制。
- 🛠️ DNA修复机制非常强大,能够通过多层校对来修复错误。
- 🍃 叶酸缺乏会破坏DNA修复机制,导致多种疾病。
- 🤰 孕妇常服用的合成叶酸(folic acid)有助于预防神经管缺陷。
- 🧬 MTHFR基因突变会影响叶酸转化为活性形式的能力,可能导致未代谢叶酸积累。
- 💊 合成叶酸(folic acid)过量可能与某些健康问题相关,如增加自闭症风险。
- 🌱 推荐食用富含天然叶酸的食物,如深色绿叶蔬菜。
- 🔄 叶酸和维生素B12共同作用,叶酸过量可能导致B12缺乏。
- 🚫 高同型半氨酸(homocysteine)水平可能增加心脏病和中风的风险,并影响血管健康。
- 💊 对于有MTHFR基因突变的人来说,使用不需转化的活性形式B9,如甲基叶酸(methylfolate),可能是更好的选择。
Q & A
维生素B9缺乏可能导致什么健康问题?
-维生素B9缺乏可能导致DNA损伤,这种损伤可能进一步导致癌症。
为什么维生素B9对DNA复制和修复过程很重要?
-维生素B9是一种辅酶,帮助制造RNA和DNA,这些是细胞内的蓝图,是构建整个身体的指令。叶酸缺乏不仅会导致DNA断裂和损伤,还会损害DNA修复过程。
DNA修复机制是如何工作的?
-DNA修复机制通过多层校对和纠错过程来确保DNA复制的准确性。如果发现错误,会有专门的单元介入修复,有时需要切除并替换一部分,有时则只需稍微调整代码以确保准确无误。
叶酸和合成叶酸(维生素B9的合成版本)有何不同?
-叶酸是维生素B9的天然形式,而合成叶酸是其合成版本。合成叶酸被广泛用于预防神经管缺陷等出生缺陷,但对某些基因突变的人来说,合成叶酸可能无法有效转化,甚至可能积累为未代谢的叶酸酸,导致问题。
MTHFR基因突变与维生素B9有什么关系?
-MTHFR基因突变涉及一种酶,该酶负责将合成叶酸转化为活性形式以供身体使用。如果这个基因出现问题,身体获取活性维生素B9的能力会大大受限。
为什么甲基叶酸(methylfolate)对于有MTHFR基因突变的人来说是一个更好的选择?
-甲基叶酸是一种不需要酶转化即可被身体使用的维生素B9形式,因此对于有MTHFR基因突变的人来说,它更容易被吸收,不会受到基因问题的影响。
合成叶酸在食品供应中的作用是什么?
-合成叶酸被添加到多种食品中,如谷物、面包、意大利面、饼干、能量饮料等,作为营养强化的一部分,以预防某些健康问题,如贫血。
合成叶酸摄入过多可能导致哪些问题?
-合成叶酸摄入过多可能导致未代谢的叶酸酸积累,对于有MTHFR基因突变的人来说尤其如此。此外,还有研究表明,孕妇摄入过多的合成叶酸可能会增加孩子患自闭症的风险。
B9和B12之间有什么关系?
-B9(叶酸)和B12(钴胺素)共同工作,如果一个人有遗传问题并且摄入大量的合成叶酸以预防贫血或其他问题,可能会导致B12缺乏,从而可能增加同型半胱氨酸水平,这是一种与心脏病和中风风险增加有关的不良化合物。
同型半胱氨酸水平升高会带来哪些健康风险?
-同型半胱氨酸水平升高可以增加心脏病和中风的风险,影响血管内皮组织,抑制一氧化氮的产生,可能导致高血压和其他健康问题,包括勃起功能障碍。
如何确保不摄入过多的合成叶酸?
-由于合成叶酸被添加到许多食品中,选择未添加叶酸的食品是一个方法。更重要的是,增加天然富含维生素B9的食物摄入,如深色绿叶蔬菜。
为什么维生素B9对于预防癌症很重要?
-维生素B9有助于保护DNA免受编码问题的影响,如果体内有适量的B9,它可以保护DNA免受可能导致癌症的损伤。
Outlines
😀 叶酸缺乏与DNA损伤及癌症风险
本段讨论了叶酸(维生素B9)缺乏可能导致DNA损伤,进而引发癌症的问题。提到了叶酸在DNA复制和修复过程中的重要作用,以及叶酸缺乏如何影响这一机制,造成DNA损伤累积,增加癌症风险。同时,还探讨了合成叶酸(叶酸酸)与天然叶酸(叶酸)的区别,以及MTHFR基因突变对叶酸代谢的影响,建议通过食用富含天然叶酸的食物,如深色绿叶蔬菜,来补充叶酸,并注意避免过量摄入合成叶酸可能带来的风险。
🧬 叶酸、癌症发生与基因突变的关系
这段内容深入讨论了叶酸(B9)在预防DNA损伤和癌症发生中的作用,以及过量叶酸可能带来的风险。强调了正确量的B9对保护DNA免受损伤的重要性,并指出过量叶酸可能促进癌细胞生长。对于携带MTHFR基因突变的人来说,合成叶酸可能无法有效转化,因此推荐使用甲基叶酸(methylfolate),它不需要酶转化即可被身体利用。同时,指出过量合成叶酸可能与自闭症风险增加有关,并且可能掩盖B12缺乏,导致同型半胱氨酸水平升高,增加心脏病和中风的风险。最后,建议通过食用天然富含叶酸的食物来补充,而不是依赖食品中的合成叶酸。
Mindmap
Keywords
💡维生素B9
💡DNA损伤
💡X射线
💡DNA修复
💡合成叶酸
💡天然叶酸
💡甲基叶酸
💡MTHFR基因突变
💡神经管缺陷
💡同型半胱氨酸
💡B12缺乏
Highlights
维生素B9(叶酸)缺乏可能导致DNA损伤,进而引发癌症。
叶酸缺乏造成的损伤与X射线的电离辐射造成的损伤相同。
叶酸是一种辅酶,帮助制造RNA和DNA。
叶酸不足不仅会导致DNA断裂和损伤,还会损害DNA修复过程。
DNA是身体的蓝图,其复制过程非常复杂且精确。
DNA修复机制非常强大,能够扫描并修复错误。
叶酸缺乏会导致DNA修复机制出现大量错误,可能引发各种疾病。
合成叶酸(维生素B9的合成形式)与天然叶酸之间存在差异。
孕妇常服用的孕前维生素含有合成叶酸,有助于预防神经管缺陷。
MTHFR基因变异影响叶酸转化为活性形式,可能导致叶酸缺乏。
合成叶酸(叶酸酸)积累可能导致问题,尤其是对于有MTHFR基因变异的人。
适量的维生素B9可以保护DNA免受损伤,预防癌症的发生。
过量的叶酸酸可能促进癌细胞生长,尤其是有MTHFR基因变异的人。
甲基叶酸(methylfolate)是一种无需转化即可被身体使用的维生素B9形式。
合成叶酸被广泛添加到食品中,可能造成过量摄入。
推荐食用富含天然叶酸的食物,如深色绿叶蔬菜。
MTHFR基因变异的人如果摄入过多的合成叶酸,可能会掩盖维生素B12的缺乏。
同型半胱氨酸(homocysteine)水平升高可能增加心脏病和中风的风险。
同型半胱氨酸还可能影响血管内皮组织,导致高血压和其他问题。
Transcripts
now I've talked about this topic uh I
think two years ago at my Summit um it
may be in other videos but I wanted to
create one video just on this one topic
because it's actually very very
important I think you're going to find
it very very interesting but
fate vitamin B9 deficiency has a
potential to cause DNA damage which can
then lead to cancer when you go to the
hospital you get an x-ray do you have
any concern about getting x-rays or a
cast scan do you mind them taking an
x-ray um does it bother you and if the
answer is yes then the question is why
why are you concerned about getting
x-rays well probably because it has
radiation correct did you realize that a
folate deficiency creates the same
damage as ionizing radiation from
x-rays yes there's an interesting story
about this by Professor Bruce Ames I put
a link down below for that but full
eight is a vitamin that is a co-enzyme
so it's a helper enzyme specifically to
help you make RNA in DNA so RNA is a
copy of DNA and DNA is the blueprints
that are in your cells that are the
instructions to make the entire body so
when a person is deficient in folate not
only are you going to get all sorts of
DNA breaks and damage but it's also
going to impair the DNA
repair process which can then lead to
cancer now here we have the DNA the
blueprints of your body These Blueprints
actually are the building blocks for
your entire all your body tissue now
what we're looking at is These
Blueprints going through this amazing
machine you have this machine that is
like a zipper and it's unzipping these
two little strands that are connected
called DNA
okay and and this zipper is spinning at
a speed that's equivalent to a jet
engine and what's happening here is your
DNA is being copied in a very
interesting way one strand is going one
way but it's not just copying a piece of
paper it's copying something in three
dimensions fascinating and on top of
everything else you have several layers
of airor Correction or proof reading
going on so it's kind of like this
little program that will scan the code
to look for errors and it's extremely
accurate and if there is an err another
unit will come in there and fix it so
there's several types of errors that can
happen and sometimes it'll have to cut
out a section and replace it um and
other times they can just manipulate the
code a little bit to make sure it's
exact so as you can see this DNA repair
mechanism is simply awesome and just by
a simple vitamin deficiency like a
folate deficiency you're going to create
massive errors in this um mechanism and
these errors can lead to all sorts of
diseases so I hope this demonstration
gave you a little more motivation to eat
healthier let's talk about the
difference between folic acid and I'm
talking about the synthetic version of
vitamin
B9 as well as folate the natural version
are they the same you know so many women
while when they're pregnant they start
taking a prenatal that is just loaded up
with this synthetic folic acid and
there's a lot of data to show that that
can help prevent things like neurot tube
defects which is an incomplete closure
of the spinal column and so it's true it
does do that but uh with more more
people recognizing that uh they may have
a mutation with a certain Gene that
relates to uh B9 uh I think we should
talk about it there's a very common
problem with a gene that is called
MTHFR it involves an enzyme in
converting um folic acid into the active
form so your body can use it so if you
have a problem with this Gene your
ability to get this um active form of B9
is greatly inhibited and if you end up
taking this synthetic version which
called folic acid
you can have a lot of problems because
it can accumulate as uh
unmetabolized folic acid now it probably
is not going to become a problem unless
you take large amounts but the fact that
if you have this mutation you're going
to be deficient so there's this delicate
balance of getting just the right amount
of this B9 because here's the thing B9
actually does a lot of things it
protects against the initiation of
cancer because B9 helps to protect the
DNA against um problems with the code
and if you have just the right amount of
B9 it can protect this damage within the
DNA that can potentially then lead to
cancer B9 also is involved in the
initiation of new cancer cells that
sounds like it's kind of conflicting on
one hand it prevents the initiation of
new cancer cells but on the other hand
it can actually help grow this canc
cells but based on the data that I read
it's really when you have way too much
of this folic acid so this complicates
things because with this mutation you
need more than you normally should have
yet you don't want to get too much so
the solution of to this problem is to
take a type of
B9 that doesn't have to be converted
okay it doesn't require this enzyme so
in other words this mutation is a no
issue why because it's ready to be used
and can be easily absorbed in the body
and that is called methylfolate and
there's other long names for it but
basically it's a type of Bine that's
easily absorbed and it doesn't require
these other enzyme reactions like the
synthetic folic acid now sometimes
you'll hear reports and studies that
show that regardless of this mutation
you still need to take this synthetic
folic acid to prevent uh neural tube
defects because there is no studies
comparing this synthetic folic acid to
this methyl folate and that's true and
they're not going to do studies because
to do that on humans right it's too
dangerous it's too unethical so it's not
going to be done so you're just going to
have to use common sense if even if you
compare these two uh versions of B9 it's
going to be more effective for you to
get enough B9 in your blood using the
methyl folate version the other thing is
if you have this mutation there's some
studies to show that if you're taking
way too much synthetic folic acid or the
mother's taking way too much that can
increase the risk of autism by a factor
of
17x and this synthetic folic acid cannot
fix this mutated Gene in fact it can
block the natural version of fate and
potentially increase your risk of
getting cancer so that being said the
question is how do I make sure I'm not
getting uh too much of this synthetic
version well unfortunately it's put in
our food supply it's as part of the
fortification for all cereals okay that
kids eat also adults it's used in all
the breads the pasta the cereal the
crackers the biscuits the energy drinks
a lot of the synthetic vitamins as well
as uh fortified nutritional yeast that's
why I always recommend to get the
unfortified version of that even more
importantly is to start to consume the
foods that are high in this natural B9
which is consuming more dark leafy green
vegetables the last point I want to
bring up is that if a person has this
genetic problem and they're taking a lot
of FC acid to prevent let's say anemia
or some other problem what can happen is
they can end up chem caging a B12
deficiency because B9 and b12 work
together and that can create problems
with an increase of something else that
I want to kind of just summarize very
simply it's called homosysteine
homocystine is a a bad compound that can
increase your risk of getting heart
attacks and strokes and homosysteine
also affects the inside of the artery
the endothelial tissue it inhibits um
this nitric oxide o side that then can
cause you to have high blood pressure
and create all sorts of problems but
it's not just a problem inside your
heart it can affect other areas as well
because if there's a diminished nitric
oxide you can end up with erectile
dysfunction now since you're on this
topic if you have not seen my video on
B12 that would be the next video to
watch check it out
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