How To Reverse Diabetes Type 2 (Explanation, Before / After)
Summary
TLDRThe speaker explains the concept of insulin resistance as a protective mechanism rather than a harmful condition, using analogies like overeating and overcharging a battery. Insulin resistance occurs when cells have enough glucose and 'close their mouths' to avoid overload, which prevents cellular damage. This process, misunderstood as the cause of diabetes, actually saves cells from being overwhelmed by excess glucose. The speaker encourages managing metabolic health through diet and lifestyle changes rather than relying on supplements or medication, promoting glucose balance without excessive carb intake.
Takeaways
- 🛡️ Insulin resistance is a protective mechanism rather than a pathological condition; it helps cells manage energy overload and prevent damage.
- 🍰 The analogy of Bruce from Matilda eating too much cake illustrates how the body signals when it has reached its energy capacity.
- 🔋 Just like a battery can only store a limited amount of charge, cells have a limited capacity for glucose intake before they must stop to avoid damage.
- 🚫 Insulin resistance occurs when cells no longer need more glucose, leading them to 'close' glucose channels (GLUT4), which prevents further glucose intake.
- ⚡ The body produces glucose even without external carbohydrates through gluconeogenesis, which supplies the exact amount of glucose required.
- 💪 Exercise prompts the body to produce glucose naturally from stored glycogen, without the need for dietary carbohydrates.
- 🥄 Constantly eating carbs forces the body to manage an overload of glucose, causing cells to protect themselves by becoming insulin resistant.
- 📉 Insulin resistance is not the cause of diabetes but a response to excess glucose; avoiding constant carb intake can help reduce insulin resistance.
- 🔄 The Randall cycle prevents excess glucose from entering cells, acting as a critical mechanism to maintain cellular health.
- 🚫 Supplements are not a magic solution for diabetes; proper diet is the most powerful method to control insulin levels and improve metabolic health.
Q & A
What is the main point the speaker is making about insulin resistance?
-The speaker argues that insulin resistance is not a harmful condition, but rather a protective mechanism that prevents cells from taking in excess glucose, which could otherwise damage them.
How does the speaker use the analogy of Bruce from Matilda to explain insulin resistance?
-The speaker compares Bruce's reaction to overeating cake, where his body signals him to stop, to the way cells protect themselves by becoming insulin-resistant when they've received enough glucose. This is to prevent further damage from excess intake.
What role does insulin play in glucose regulation according to the script?
-Insulin facilitates the entry of glucose into cells. However, if cells have enough energy, they stop accepting glucose, which results in insulin resistance as a protective measure.
What happens when cells reach their capacity for glucose?
-When cells reach their capacity for glucose, they become insulin-resistant, essentially 'closing their mouth' to stop further glucose intake to prevent cellular damage.
What is gluconeogenesis, and how does it help maintain blood glucose levels?
-Gluconeogenesis is the process by which the body generates glucose internally, even in the absence of dietary carbohydrates. It helps maintain stable blood glucose levels, providing the exact amount needed, especially during activities like exercise.
Why does the speaker claim insulin resistance is a life-saving mechanism?
-The speaker claims insulin resistance is life-saving because it protects cells from being overloaded with glucose, which could lead to cellular damage and bioenergetic instability.
What is the Randall cycle, and how is it related to the concept of insulin resistance?
-The Randall cycle, discovered in 1963, explains how cells manage the balance between fat and glucose as energy sources. It helps to prevent excess glucose from damaging cells, supporting the speaker's point that insulin resistance is a protective mechanism.
What happens to glucose that can't enter cells due to insulin resistance?
-Glucose that can't enter cells remains in the bloodstream, where it can damage cells in the circulatory system, as these cells are less complex and more easily replaced, but sustained damage leads to chronic health problems.
How does the speaker explain the rise in blood glucose during exercise even without carbohydrate consumption?
-During exercise, the body senses a need for more energy and triggers the breakdown of glycogen to produce glucose. This raises blood glucose levels even without carbohydrate consumption, showing the body can regulate energy production efficiently.
What is the speaker's stance on supplements for managing diabetes?
-The speaker believes that most supplements do not significantly help manage diabetes and that diet is far more important. While some supplements may have a place, they can't reverse diabetes if the root cause, such as excessive carbohydrate intake, is not addressed.
Outlines
💉 Understanding Insulin Resistance
The speaker begins by addressing the concept of insulin resistance, emphasizing that it is not a negative condition but rather a protective mechanism for the body. They explain that insulin resistance is often misunderstood as the cause of health issues when it is actually a response to an overload of glucose in the bloodstream. The analogy of forcing cake on someone until they feel sick illustrates how the body signals when it has reached its limit. Similarly, charging a battery beyond its capacity can lead to dangerous outcomes. The speaker uses these examples to explain how insulin resistance works: when cells are flooded with more glucose than they can handle, they 'close their mouths' to prevent further glucose intake, thus protecting the cells from damage.
🔋 The Cellular Response to Overload
In this section, the speaker delves deeper into how cells respond to an excess of glucose. They explain the process of gluconeogenesis, where the body produces glucose as needed without the consumption of carbohydrates. The analogy of a battery being charged to 100% and then stopping is used to illustrate how the body maintains a balance. The speaker then discusses what happens when more glucose is introduced into the bloodstream than the cells can handle, leading to the cell's protective response of closing the glucose transporter (GLUT4). This mechanism is likened to Bruce not wanting more cake, where the feeling of sickness leads to a physical response to prevent further intake. The speaker argues that insulin resistance is not a pathology but a natural defense against bioenergetic instability.
🍰 The Impact of Diet on Insulin Resistance
The final paragraph addresses the role of diet in insulin resistance. The speaker argues that the problem lies not in the concept of insulin resistance but in the external factors, such as dietary habits, that cause blood glucose levels to rise beyond what the body considers necessary. They suggest that by reducing carbohydrate intake, one can observe a normalization of insulin-related processes, potentially reversing a Type 2 diabetes diagnosis. The speaker also touches on the limitations of medical education regarding the understanding of insulin resistance and encourages viewers to experiment with their diet to observe the effects on their glucose levels. They conclude by emphasizing the importance of proper diet over supplements for maintaining health and preventing disease.
Mindmap
Keywords
💡Insulin Resistance
💡Glucose
💡Gluconeogenesis
💡GLUT-4
💡Randall Cycle
💡Beta Cells
💡Blood Glucose Levels
💡Cytolysis
💡HbA1c
💡Fructose
Highlights
Insulin resistance is a protective mechanism that prevents cells from being damaged by excessive glucose.
The concept of insulin resistance is not the cause of diabetes, but a way for the body to protect itself from excessive energy intake.
Cells, like batteries, have a fixed capacity for energy, and when they receive more than they can handle, they shut down pathways to prevent overload.
When we consume too many carbohydrates, the cells close their 'mouth' (GLUT4) to prevent excess glucose from entering and damaging the cells.
Gluconeogenesis is the process by which the body creates its own glucose when needed, and this happens without the intake of carbohydrates.
Excess glucose in the bloodstream can damage circulatory system cells, which are replaced more frequently due to their less complex structure.
Insulin resistance is part of a natural biological process selected over millions of years to protect cells from bioenergetic instability.
In diabetes, the issue isn't insulin resistance but the overconsumption of carbohydrates that overwhelms the body's glucose regulation mechanisms.
The Randall cycle, a metabolic discovery from 1963, explains how cells regulate energy intake and protect themselves from excess glucose.
Gluconeogenesis ensures the body only produces the exact amount of glucose needed for energy, preventing overload when carbohydrates are not consumed.
The analogy of Bruce from 'Matilda' being forced to eat cake illustrates how the body signals when it has had enough, similar to insulin resistance.
Measuring glucose levels via HBA1C may not give a complete picture, as it doesn't account for the damaging effects of fructose in the body.
Fructose, often found alongside glucose, has its own damaging effects and should be considered when evaluating metabolic health.
The speaker emphasizes that reversing type 2 diabetes can be achieved through dietary changes, often within 3 to 4 weeks.
Continuous Glucose Monitors (CGMs) show that blood glucose levels can remain stable even without carbohydrate intake, supporting the idea of gluconeogenesis.
Transcripts
I know saying insulin resistance saves
your life sounds a bit weird but once
you delve deep into it it does actually
make sense that's not clickbait and
you'll understand exactly why it's a
true statement to explain the cause of
so-call insulin resistance and and
really give lay people a full
understanding in such a way that you can
take control of your metabolic Health
without relying on on doctors like
myself uh and and yes I am one I'm going
to go into analogy
that even kids can understand and then
equate those to the bioenergetics
surrounding this concept that we label
as inulin
resistance apologies if you find the
analogies patronizing but if you do then
and clearly they're not meant for you
and you can just skip ahead I'm going to
use them so that even kids in school can
watch this and learn it as early as
possible in life uh when Bruce from the
film Matilda was forced to eat cake he
loved it to start with but eventually
there was so much cake put in him that
his b body naturally signaled him to
stop with things like feelings of being
sick and maybe some abdominal pain etc
etc the body recognized it's dangerous
to have more so it sent these signals if
someone does that Force feeding to you
you'll get to a point where you
physically put your hands up to block
your mouth even uh there was a
protective process that prevented
further food from going into his mouth
in order to save him from serious issues
I'm sure this is pretty easy to
understand when we charge a battery
there's only so much charge you can you
can put into it now I'm not going to go
into what charge is because we'd be here
all day discussing whether anyone can
actually Define an electron but for what
it's worth if you try to force more
charge uh than is storable into a
battery somehow like in a car I think
it's pretty safe to say that something
potentially dangerous is going to happen
maybe even some sort of explosion if the
batter is big enough and your charging
process is strong enough enough
too both of these are pretty easy
analogies to follow I'm sure they
represent trying to put chemical or
electrical energy into something that
has a fixed capacity of what it can take
in but when it comes to diabetes people
think insulin resistance is the cause
insulin resistance as you're about to
see from transferring these analogies is
the way your cells save your life like
Bruce's Body making him feel sick to get
him to stop because the cells only have
a fixed capacity of what they can take
in just like Bruce a stomach or a
hypothetical battery let me explain and
I'll try to use layman's terms as much
as possible again when we eat
carbohydrates this puts externally
source to glucose into our bloodstream
in other words it's glucose not from our
own body making it on purpose to be in
the bloodstream which can come about
during things like exercise this is this
is the most potent signal that we have
to tell cells in the pancreas called
beta cells to make insulin alpha cells
are something else they make glucagon
which is a different topic for a
different day there are other things
that can also signal insulin production
too um but they're going to be less
potent like certain amino acids like
Lucine to name just one but dietary
carbohydrates are you the most potent
inducer of insulin production than
things like Lucine or certain amino
acids now once the insulin is around
people jump to thinking that glucose is
then going into the cells and that's
great this is where you get con
misunderstandings and I'm going to
challenge your thoughts on this if the
cell needs energy to carry its jobs and
glucose which provides energy going into
it can be
beneficial but what if the cells don't
need more energy when we feed Bruce it
can be fine if he's hungry but what
about when he's so full that he wants to
throw up because his body needs to take
drastic measures to get him to
stop if we charge a battery when it's
empty I'm sure it's fine but if it's
charged and then we some
try to get a big machine to overload it
beyond what it needs do you think you're
going to be safe during that
process let's pretend we don't eat any
carbs so there's no externally sourced
blood glucose how do you think people
like myself have a blood glucose level
when we eat no carbs well we have one
because our body can make glucose by
itself when never needed using a process
called glucon neo genesis glucose new
make and gu guess what it makes exactly
the right amount that's needed we we
feed Bruce just the right amount to
satisfy his hunger but not make him sick
we charge the battery just the right
amount to reach 100% And then stop our
body knows what level is needed at all
times as a result of millions of years
of evolution this is why when I do
exercise my continuous glucose monitor
shows my blood glucose Rising even when
I didn't eat carbs because my body
senses a need for more energy due to
exercise and then it desdes to produce
some by breaking down glucose stores
called glycogen and then charging my
battery only enough to reach 100% by
sending the perfect amount of glucose to
cells using the bloodstream but it only
sends the exact amount needed but what
happens when we put more than is needed
into the bloodstream for example by
using externally sourced carbohydrates
when your cell has been supplied with
enough already thanks to glucon Genesis
so now we're forcing in more than is
technically needed by forcing glucose
from an area of high concentration I the
bloodstream to of to an area of
relatively low concentration I.E the
cell inside the cell in other words it
moves down its concentration gradient
which is a technical term water moves in
the same way down concentration
gradients or water potential gradients
inside organisms but when more water is
needed is forced into a cell it can
actually damage the cell this concept of
putting in more than is needed being
damaging is the same for glucose too I
know some may not believe me but you can
see the proof of this in your own body
if you wish so you can test to see if
it's true just keep putting in more and
more carbohydrates in your mouth and
watch your glucose level sustain for
long periods of time because insulin
isn't clearing it a crude example again
is Bruce feeling sick to stop more cake
coming in in order to prevent damage
that feeling of being sick makes him
close his mouth in the analogy and it
has an equivalent in the cell when the
cell feels sick from too much cake
glucose it closes its mouth too it
closes it to stop more glucose entering
and it happens because glucose
represents energy and cells like
batteries can only cope with so much at
one time without getting damaged the
mouth closing on the cell is called glut
four which stands for glucose
transporter four this cellular mouth
shuts out glucose because it does want
any anymore and when that happens
insulin can no longer open this mouth to
put more glucose in you see we have
protection mechanisms in ourselves to
make sure too much of anything doesn't
come in whether it's something like
water which which isn't done with glut
for by the way or in this case glucose
it's what prevents cell death or if you
want to know the technical term
cytolysis this is why so-called insulin
resistance is is a mechanism of saving
your life it's a mechanism that prevents
Sal death from catastrophic bioenergetic
instability to use a technical phrase
for a second forgive me happens because
of an observable phenomena called the
Randall cycle discovered by S Philip
Randall and published in 1963 it's a
really important Discovery in the field
of metabolism um but it's too big to go
into for this video right now otherwise
it'll be even longer than I I planned it
to be uh maybe I can do it in another
video sometime but in short in a
nutshell it exists to stop ose from
damaging cells from being inside them in
in too high a quantity relative to the
ideal amount so I always teach my
patients to realize that this thing that
we term insulin resistance it's it's not
a pathology or a problem and it's
certainly isn't the cause of diabetes
it's it's a protection mechanism that's
meant to occur in order to save
ourselves it's a normal uh it's it's a
required biological pathway that's been
selected for over millions of years to
ensure our survival and subsequent
Optimal Health and and and and function
and and ability to
reproduce What happens when we shut that
glute for mouth then well apart from
being given the label of someone who's
insulin resistant now that's not the end
of the story because if the door shut
the glucose has to go somewhere even if
it can't go into the cells the cake
still has to go somewhere even if Bruce
doesn't want to eat it does someone else
have it or does it end up in the bin
sorry if the analogies are a bit
patronizing but I'm kind of speaking
speaking to my uh Teenage self here and
telling him things I wish I'd known when
I was younger um well basically the
glucose ends up with someone else
specifically when it hangs around in the
bloodstream it can then cause damage to
cells of the circulatory system and this
happens because these cells are more
able to be sacrificed because the the
cells themselves are a little bit less
complex in structure and so they replace
more often partly because being less
complex means they're easy to make so a
library book that gets replaced very
often can take damages to its Pages
because it will be replaced by a new one
very soon anyway those cells in the
circulation system will replace more
rapidly so they can take some short-term
sacrifice to their Pages before the
librarian gets a replacement copy
brought in in a few months time from the
bone marrow if the new ones get damaged
too and it just never stops then
obviously you got chronic issues and and
your health is just going to decline
like this when we look at Evolution just
to State the obvious for a second bear
with me we didn't have Uber Eats 100,000
years ago to have any amount of food any
number of times placed in our laps with
practically Zero Energy spent to obtain
it so we clearly haven't evolved with
repeated or constant external glucose
loading on the blood as a darwinian
positive selection pressure so we're not
adapted in my opinion only for for what
it's worth um to be eating carbs all day
non-stop and we can maintain our blood
glucose with great consistency even
without eating carbs in the diet hence
my consistent glucose level without
eating any carbs and if you think about
it for those that disagree which you're
welcome to of course the very existence
of the process of gluconeogenesis is the
ability you know I.E the the the ability
we have to make glucose anytime we need
and always in the exact amount required
from other
materials that wouldn't have existed if
we needed to eat carbohydrates
overall the disease process or the
problem in things like diabetes isn't
the concept of insulin resistance it's
instead it's it's the thing that causes
that glut for mouth and the cell to
close which is externally sourced
glucose making blood levels of glucose
rise more than the body deems necessary
in such a way that the cell then needs
to protect itself from your diet and
lifestyle choices and again you can try
this yourself to try and prove me wrong
if you wish um just over carbs watch
your insulin resistance take form to
gain a Diabetes Type 2 diagnosis then
stop the carbs and then watch the
insulin related processes normalize
again so that you're no longer
diabetic this is why there's no magic
supplement that reverses diabetes can
take a supplement but if your battery is
still being overcharged and it still
won't let any more electricity in will
it if you're still putting carbs in your
mouth and the glute 4 will still be
closed to any glucose that turns up I
really urge you to stop believing in
supplements that can suddenly cure
things sure supplements and neutrals can
have a place in someone's diet at times
but the most powerful anti-aging thing
anyone can do is to just Eat Right
supplements and things are are great
ways for companies to make extra cash
most of the time there's very few that
are actually credible and that I
personally have seen make significant
differences to my patients based on
their feedback maybe I can do a on on
some supplements uh one day I mean I did
make a video on them a while back but
even then you know that was only in the
context of someone that absolutely needs
to take those things if the diet's right
then you don't need to buy anything
extra uh but you know going back to the
glucose Please be aware that when you
measure things like hba1c on a blood
test to measure the glucose level
control it might be a decent way to get
a very rough recent historical picture
of your glucose
metabolism but the ISS you have there is
that it doesn't tell you about fructose
which has its own set of of damaging
characteristics in the body and where we
find glucose in nature we find fructose
too all the time and and as to what
ultimately happens to the glucose after
the point in the story that we got to
when it hangs around in the bloodstream
because Gluk 4 is closed in terms of
things like being turned into fat and
how the liver is involved and why
fructose is basically poison
um how triglycerides come into the
picture I think I've spoken quite long
here already so I'll leave that for part
two but quickly for those that don't
believe me because your doctor has never
told you any of this well there are many
reasons for that firstly we're not
taught the Randle cycle in our
undergraduate well I certainly wasn't
anyway and secondly you don't need to
hear from a doctor what you can see with
your own two eyes to be true try a CGM
and watch your blood glucose levels
maintain even without dietary
carbohydrates ideally you know change
your diet over two to three months if
you if you want to do it uh
safely um but on you know on average it
takes me 3 to four weeks to completely
reverse someone's type 2 diabetes
nowadays I'll leave a picture on screen
here of a before and after of fasted
insulin results of one of my patients
from last week who's now off all
medication so you can see for yourself
exactly what happens
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