How to fix SIBO & Prevent Recurrence

Dr. Norm Robillard - Fast Tract Diet™
3 Aug 202224:53

Summary

TLDRNorm Rebelad, founder of the Digestive Health Institute, discusses Small Intestinal Bacterial Overgrowth (SIBO) and effective strategies for addressing it. He covers SIBO's causes, symptoms, and the role of gut bacteria in nutrient malabsorption. Diagnostic methods like breath tests and treatment options, including antibiotics, herbal remedies, probiotics, and diet changes, are explained. Rebelad emphasizes the importance of addressing the underlying causes of SIBO, limiting fermentable carbohydrates, and adopting pro-digestion habits to prevent recurrence. He also suggests the Fast Track Diet for managing symptoms and restoring gut health.

Takeaways

  • 🔍 SIBO (Small Intestinal Bacterial Overgrowth) is a form of dysbiosis where bacteria overgrow in the small intestine, causing digestive issues and nutrient malabsorption.
  • 📜 SIBO was first described in 1949 by Fraser as fecal bacteria colonizing the small intestine, competing with the host for nutrients.
  • 🦠 Research identifies several bacteria linked to SIBO, including E. coli, Klebsiella, and other native and migratory strains, with some studies indicating a loss of microbial diversity may contribute to symptoms.
  • 💡 Common symptoms of SIBO include bloating, gas, abdominal pain, diarrhea, constipation, fatigue, and more severe cases may involve weight loss and nutrient deficiencies.
  • 🔬 Diagnosing SIBO is primarily done through breath testing (hydrogen, methane, and hydrogen sulfide) or bacterial culturing, though both methods have limitations.
  • 💊 Antibiotics like rifaximin and neomycin are common treatments, but they often only provide temporary relief and do not address the root causes of SIBO.
  • 🌿 Herbal antimicrobials and probiotics are alternative treatments, with some studies showing that certain probiotics and herbs can be as effective as antibiotics in managing SIBO.
  • 🍽️ Diet plays a crucial role in managing SIBO, especially by limiting fermentable carbohydrates (lactose, fructose, resistant starch, etc.) to reduce bacterial fuel and alleviate symptoms.
  • 🔄 Long-term treatment for SIBO should focus on identifying and addressing underlying causes such as low stomach acid, motility issues, or enzyme deficiencies to prevent recurrence.
  • 📚 Further information and personalized guidance on SIBO management can be found in resources like the Fast Track Diet books, app, and consultation services.

Q & A

  • What is SIBO (Small Intestinal Bacterial Overgrowth)?

    -SIBO is a condition where there is an overgrowth of bacteria in the small intestine, typically involving the native gut microbiota rather than an invading pathogen. These bacteria can disrupt digestion and cause symptoms such as gas, bloating, and malabsorption.

  • What are the main bacterial strains involved in SIBO?

    -Common bacterial strains found in SIBO include E. coli, Klebsiella, Streptococcus, Lactobacillus, Bacteroides, Clostridia, and Methanobrevibacter smithii, among others. Research is still determining the most prominent strains.

  • What are some common symptoms of SIBO?

    -SIBO symptoms include gas, bloating, abdominal pain, diarrhea, constipation (often linked to methanogen overgrowth), acid reflux, fatigue, brain fog, and skin issues. More severe symptoms can include malabsorption, weight loss, and nutrient deficiencies.

  • What is the relationship between SIBO and other health conditions?

    -SIBO is linked to numerous health conditions including IBS, GERD, Crohn’s disease, diabetes, fibromyalgia, chronic fatigue syndrome, asthma, and autoimmune diseases such as celiac disease and Hashimoto’s thyroiditis.

  • How is SIBO diagnosed?

    -SIBO is typically diagnosed through breath testing or culturing bacteria from the small intestine. Breath tests measure gases like hydrogen, methane, and hydrogen sulfide, which are produced by bacterial fermentation of carbohydrates in the small intestine.

  • What are the challenges with current SIBO breath testing methods?

    -Breath testing can have limitations such as false positives, particularly with rapid intestinal transit times, and difficulties detecting SIBO in the lower part of the small intestine with glucose-based tests.

  • What treatment options are available for SIBO?

    -Treatment options include antibiotics like rifaximin and neomycin, herbal antimicrobials, probiotics, dietary changes, and supplements aimed at improving digestion and nutrient absorption. However, antibiotics may not prevent recurrence without addressing underlying causes.

  • Are antibiotics effective in treating SIBO?

    -Antibiotics can reduce bacterial overgrowth and improve symptoms in some cases, but they don't address underlying causes, making relapse common. Rifaximin, while relatively safe, has a high relapse rate, and other antibiotics can pose risks such as bacterial resistance.

  • What role do diet and dietary behaviors play in treating SIBO?

    -Diet is crucial in managing SIBO. Limiting fermentable carbohydrates (such as lactose, fructose, and resistant starch) can help reduce bacterial overgrowth and symptoms. In addition, behaviors like eating slowly and chewing well also support digestion.

  • What are some recommended dietary supplements for SIBO?

    -Supplements like multivitamins, digestive enzymes, betaine HCL, L-glutamine, zinc, and NAC may be beneficial for nutrient absorption, digestion, and mucosal support. However, over-supplementation can cause complications, so careful use is advised.

Outlines

00:00

💡 Introduction to SIBO and Its Importance

In this introductory paragraph, Norm Robillard, founder of the Digestive Health Institute, introduces the topic of SIBO (Small Intestinal Bacterial Overgrowth). He emphasizes the ongoing research on SIBO diagnostics and treatment and explains how SIBO is a form of dysbiosis where bacteria overgrow in the small intestine, causing nutrient competition and damage to the host. Several bacteria species involved in SIBO, such as E. coli and Klebsiella, are mentioned, along with the theory that loss of bacterial diversity may contribute to symptoms.

05:01

🧬 Current Understanding of SIBO Diagnosis

This paragraph discusses two main methods for diagnosing SIBO: breath testing and bacterial culturing, although neither is perfect. Breath tests, especially lactulose-based ones, are common as they detect gases like hydrogen and methane, indicating bacterial fermentation in the gut. Glucose-based tests, while specific, are less effective for diagnosing SIBO in the lower intestine. Hydrogen and methane production in SIBO is associated with symptoms like diarrhea and constipation, while a newer test, TRIOSMART, includes hydrogen sulfide as another gas linked to inflammation and mucosal damage.

10:04

💊 Antibiotic and Herbal Treatments for SIBO

Antibiotics such as rifaximin and neomycin are the most common treatments for SIBO, targeting hydrogen-producing and methane-producing bacteria, respectively. However, antibiotics often do not address underlying causes, leading to recurrence. Resistance and tolerance to antibiotics are also common, and studies show high relapse rates. Herbal antimicrobials, while promising, lack strong evidence in human trials, and the limited studies that exist suggest they may be as effective as antibiotics in some cases.

15:05

🦠 Probiotics and Their Role in SIBO Treatment

Probiotics are controversial in SIBO treatment due to the question of adding more bacteria to an already overgrown small intestine. However, studies suggest some probiotic strains may be helpful in treating SIBO. Examples include combinations of bifidobacteria and lactobacilli, which have shown significant success in clinical trials. Some probiotics also reduce methane levels and improve bowel movements in patients with methanogen overgrowth. Still, probiotics can cause initial symptoms like bloating and loose stools, so they should be introduced cautiously.

20:07

🍽️ Dietary Supplements and Considerations for SIBO

Various dietary supplements can assist with SIBO treatment, including multivitamins, digestive enzymes, and mucosal support agents. Supplements such as L-glutamine and N-acetyl cysteine may help restore the intestinal lining, while others improve digestion and reduce fermentable carbohydrate intake. However, it's important to be cautious of over-supplementation, which can cause toxicity, interact with medications, or fuel bacterial overgrowth. Long-term use of supplements lacks sufficient research, so short-term and carefully managed use is recommended.

🥗 Diet as a Key Component in SIBO Management

Diet plays a crucial role in SIBO management, specifically limiting fermentable carbohydrates like lactose, fructose, and fiber that feed overgrowing bacteria. The Fast Track Diet system developed by Norm Robillard is highlighted for its effectiveness in reducing symptoms by controlling carb intake. Robillard explains that carbohydrate intolerance, a form of malabsorption, contributes to SIBO and its associated conditions. Limiting certain carbs can restore gut pH balance, reduce gas production, and improve overall digestive health, making diet a vital part of SIBO treatment.

Mindmap

Keywords

💡SIBO (Small Intestinal Bacterial Overgrowth)

SIBO refers to a condition where there is an excessive growth of bacteria in the small intestine, which can interfere with digestion and nutrient absorption. The video discusses its symptoms, causes, diagnosis, and treatment. SIBO is associated with several digestive disorders and systemic conditions, making its proper diagnosis and management crucial. The script highlights that SIBO involves an overgrowth of bacteria native to the gut rather than an invasion by pathogens.

💡Dysbiosis

Dysbiosis is an imbalance in the microbial communities within the body, particularly in the gut. In the context of SIBO, it refers to the abnormal proliferation of bacteria in the small intestine, which disrupts the natural balance of gut flora. The video explains that SIBO is a form of dysbiosis characterized by an overgrowth of native gut bacteria, leading to various digestive and systemic symptoms.

💡Breath Testing

Breath testing is a non-invasive diagnostic method used to detect SIBO by measuring gases produced by bacteria in the small intestine. The video describes two main types of breath tests: one using lactulose and the other using glucose. It highlights the limitations of these tests, such as false positives due to rapid transit time or inability to detect lower intestinal overgrowth with glucose.

💡Antibiotic Treatment

Antibiotic treatment is a common approach to managing SIBO, aiming to reduce bacterial overgrowth. The video mentions rifaximin and a combination of rifaximin and neomycin as the primary antibiotics used. However, it also points out the limitations, such as the risk of recurrence, bacterial resistance, and the inability of antibiotics to address underlying causes of SIBO.

💡Dietary Management

Dietary management involves adjusting the diet to limit specific carbohydrates that fuel bacterial overgrowth in SIBO patients. The video discusses various diet strategies, including the Fast Track Diet, which restricts fermentable carbohydrates like lactose, fructose, and resistant starch. This approach helps manage symptoms and prevents recurrence by reducing the bacteria's food supply.

💡Leaky Gut

Leaky gut, or increased intestinal permeability, occurs when the lining of the small intestine becomes damaged, allowing undigested food particles, toxins, and bacteria to enter the bloodstream. The video links leaky gut to SIBO, noting that the overgrowth of bacteria can damage the mucosal surface, leading to systemic immune responses and potentially contributing to autoimmune diseases.

💡Methanogen Overgrowth (IMO)

Intestinal Methanogen Overgrowth (IMO) is a type of dysbiosis where archaea, such as Methanobrevibacter smithii, overproduce methane in the gut. This condition is often associated with constipation, contrasting with hydrogen-producing bacteria, which are more linked to diarrhea. The video distinguishes between SIBO and IMO, noting that both need different diagnostic and treatment approaches.

💡Underlying Causes

Addressing underlying causes is essential for the effective treatment of SIBO. The video emphasizes that without identifying and managing the root issues—such as motility disorders, low stomach acid, pancreatic insufficiency, or anatomical abnormalities—SIBO is likely to recur. This comprehensive approach is critical for long-term symptom resolution and prevention.

💡Probiotics

Probiotics are live beneficial bacteria that, when taken in adequate amounts, can help restore gut balance. The video discusses their controversial use in SIBO treatment, as adding more bacteria to an already overgrown environment seems counterintuitive. However, certain probiotics have shown potential in managing SIBO symptoms and even eradicating the condition in some studies.

💡Elemental Diet

The elemental diet is a treatment approach that involves consuming a liquid diet composed of pre-digested nutrients. This diet is designed to eliminate complex carbohydrates and reduce bacterial food sources, effectively starving the bacteria causing SIBO. The video mentions its effectiveness in resolving SIBO, particularly in cases where other treatments have failed.

Highlights

SIBO (Small Intestinal Bacterial Overgrowth) is a form of dysbiosis where native gut microbiota overgrow in the small intestine.

SIBO is linked to various health conditions, including IBS, GERD, obesity, diabetes, fibromyalgia, and autoimmune diseases like Hashimoto's and Celiac disease.

The symptoms of SIBO include gas, bloating, abdominal pain, acid reflux, diarrhea, constipation, brain fog, and fatigue.

The primary diagnostic methods for SIBO are breath testing and bacterial culture from the small intestine, with breath testing being the most common.

SIBO breath tests measure gases like hydrogen, methane, and hydrogen sulfide, produced by fermenting sugars and carbohydrates in the small intestine.

Antibiotics like rifaximin and neomycin are commonly prescribed to treat SIBO, though recurrence is common if the underlying causes are not addressed.

Herbal antimicrobials, such as oregano oil and berberine, are sometimes used for SIBO, though more research is needed to confirm their effectiveness.

Probiotics, though controversial, may help in treating SIBO. Studies have shown some probiotics resolving SIBO in specific patient groups.

Dietary strategies play a crucial role in managing SIBO, with the Fast Track Diet emphasizing limiting fermentable carbohydrates like lactose, fructose, and resistant starch.

Carbohydrate intolerance, a form of malabsorption, can contribute to SIBO by providing excess fuel for bacterial overgrowth.

Other treatments for SIBO include digestive enzymes, betaine HCL, and mucosal lining support supplements such as L-glutamine and zinc.

The elemental diet, which eliminates complex carbohydrates, is an effective treatment for SIBO in some cases.

Addressing the underlying causes of SIBO, such as low stomach acid, pancreatic insufficiency, and bile acid issues, is key to preventing recurrence.

Behavioral factors, such as meal timing, food preparation, and slow eating, are important for improving digestion and absorption in SIBO management.

Relapse rates for SIBO after antibiotic treatment can be high, with one study showing 64% of patients requiring retreatment.

Transcripts

play00:00

hi I'm Norm rebelad founder of the

play00:03

Digestive Health Institute and creator

play00:05

of the fast track diet

play00:07

today's topic is sibo small intestinal

play00:09

bacterial overgrowth and how to address

play00:12

it effectively to prevent recurrence

play00:15

sibo is a complex topic and research is

play00:18

ongoing for improving both Diagnostics

play00:21

and treatment

play00:22

let's talk about what we know so far

play00:25

what is sibo

play00:27

back in 1949 a researcher named Fraser

play00:31

described sibo as fecal bacteria

play00:34

colonizing the small intestine and

play00:36

competing with the host for essential

play00:38

nutrients and perhaps winning

play00:40

he was an expert in nutritional

play00:42

malabsorption

play00:44

and his description is still relevant

play00:46

today

play00:47

sibo is a form of dysbiosis involving an

play00:50

overgrowth of our native gut microbiota

play00:53

as opposed to an invading pathogen

play00:56

culture Studies have identified several

play00:59

different bacterial species some

play01:01

negative some native to the small

play01:03

intestine and some migrating from the

play01:05

lodge bowel into the small intestine and

play01:07

there's a wide variety of these strains

play01:09

they include strep E coli klebsiella

play01:13

Proteus staff micrococcus lactobacillus

play01:16

bacteroides clostridia villanella

play01:20

fusobacterium and peptosreptococcus

play01:24

new research is trying to determine the

play01:26

most prominent bacterial strains in sibo

play01:29

for instance the Pimentel lab reported

play01:32

that E coli aromonas and klebsiella

play01:34

species predominant a predominant on the

play01:37

other hand a group of genomics

play01:39

researchers sephorian colleagues

play01:41

suggested that it's actually a loss of

play01:44

diversity in the small intestine that's

play01:46

more important for symptoms than sibo

play01:49

itself now one limitation of that study

play01:52

potentially skewing their findings

play01:54

Placebo is that they included patients

play01:56

with other diagnoses such as celiac

play01:58

disease colitis pancreatic insufficiency

play02:01

and even patients that underwent GI

play02:03

surgery

play02:05

regardless the current prevailing view

play02:07

is that sibo sufferers have too many

play02:10

bacteria where they don't belong these

play02:12

bacteria produce proteases enzymes gases

play02:15

and other end products causing symptoms

play02:18

but also damaging the mucosal surface

play02:20

and villain

play02:22

this damage can impact the ability to

play02:24

digest and absorb nutrients minerals and

play02:28

vitamins the result is poor digestion

play02:30

which shunts nutrients to overgrowing

play02:33

bacteria cause an officious cycle of

play02:36

damage malabsorption and overgrowth in

play02:39

the words of Elaine gotcha

play02:42

sibo is linked to many digestive

play02:44

disorders and also health issues

play02:46

including IBS gerd obesity esophagitis

play02:50

Crohn's diverticulitis non-alcoholic

play02:54

fatty liver disease and cirrhosis

play02:56

diabetes fibromyalgia chronic fatigue

play02:59

syndrome asthma rosacea restless leg

play03:02

syndrome interstell Interstitial

play03:04

cystitis cystic fibrosis Parkinson

play03:07

Parkinson's disease and heart disease

play03:09

and also autoimmune conditions including

play03:12

Celiac Hashimoto's and Scleroderma as

play03:15

well as type 1 diabetes and this list

play03:17

continues to grow

play03:19

the exact number of sibo sufferers is

play03:22

unknown but it's likely well over a

play03:24

hundred million people in the U.S alone

play03:26

given the number of conditions linked to

play03:29

sibo

play03:30

so what are the symptoms of sebum

play03:33

sibo symptoms include gas bloating

play03:35

distension flatulence abdominal pain

play03:38

cramps acid reflux diarrhea nausea

play03:42

dehydration fatigue brain fog and skin

play03:45

conditions constipation is another

play03:48

common symptom that often occurs in

play03:50

concert with intestinal methanogen

play03:52

overgrowth or IMO most notably involved

play03:55

in the organism it's an Ikea methanol

play03:58

brevibacter smithii

play04:00

more severe symptoms of sibo may include

play04:02

weight loss failure to thrive in

play04:05

children

play04:05

stiatorea which is fat malabsorption

play04:08

anemia bleeding or bruising night

play04:11

blindness bone pain and fractures as

play04:14

well as leaky gut and autoimmune

play04:16

reactions these symptoms are not a

play04:18

complete surprise because sibo occurs in

play04:20

the small intestine the mucosal surface

play04:23

in the small intestine is sensitive to

play04:25

damage that not only impacts digestion

play04:27

but also impacts its barrier function

play04:30

leaky gut allows undigested food

play04:33

particles bacterial antigens and toxins

play04:35

to enter systemic circulation

play04:39

leaky gut coupled with something called

play04:41

molecular mimicry is considered a

play04:43

Hallmark of autoimmunity

play04:45

now how to diagnose sibo

play04:48

there are really only two methods at

play04:50

this time one is breath testing and the

play04:52

other is actually culturing bacteria

play04:55

from the small intestine which is

play04:56

considered the gold standard

play04:58

but neither test is truly a gold

play05:01

standard each method has drawbacks and

play05:03

limitations

play05:04

eventually better methods for sampling

play05:07

the small intestine coupled with

play05:09

Advanced genomic testing of the

play05:11

bacterial populations present will prove

play05:14

superior but when not there yet

play05:18

so right now non-invasive breath testing

play05:21

is the most common way of diagnosing

play05:23

sibo

play05:25

breath testing is based on the idea that

play05:27

excess bacteria in the small intestine

play05:29

can ferment sugars and other

play05:31

carbohydrates and produce unique gases

play05:34

these include hydrogen which can be

play05:37

further metabolized into hydrogen

play05:39

sulfide and methane in the case of

play05:41

sulfate reducing bacteria and archaea

play05:44

organisms respectively

play05:45

these gases diffuse into the bloodstream

play05:48

and they're exhaled through the lungs

play05:50

you know these gases are coming from

play05:53

your gut microbes because other than

play05:55

tiny amounts of hydrogen sulfide none of

play05:58

these gases is produced by humans

play06:01

there's two types of breath testing that

play06:03

have routinely used Placebo one uses the

play06:06

sugar lactulose it's non-digestible but

play06:09

fermentable the other uses glucose

play06:12

another fermentable type of sugar

play06:14

I recommend lactulose breath testing

play06:16

even though it's less specific for sibo

play06:19

with more false positives it's more

play06:22

sensitive at detecting sibo throughout

play06:24

the length of the small intestine

play06:26

the problem with glucose is that it's

play06:28

rapidly absorbed in the early part of

play06:31

the small intestine so it can't detect

play06:33

sibo in the lower part of the small

play06:35

intestine very well

play06:38

most breath tests measure two gases

play06:41

hydrogen and methane hydrogen is linked

play06:43

mostly to diarrhea while methane tends

play06:46

that's produced by these Ikea tends to

play06:48

be linked with constipation

play06:49

the newest breath test called Trio smut

play06:52

measures three gases hydrogen methane

play06:55

and also hydrogen sulfide

play06:57

hydrogen sulfide is a gas produced by

play07:00

sulfate reducing bacteria and there's a

play07:03

wide variety of these to sulfavibrio to

play07:05

sulfobacter and desulfur bulbous but

play07:08

also below Fila

play07:10

pseudomonas citrobacter aeromonas and

play07:13

several others

play07:15

levels hydrogen sulfide is actually a

play07:18

beneficial anti-inflammatory

play07:20

gazotransmitter or signaling molecule

play07:23

contributing to physiological health

play07:26

but excessive amounts have been linked

play07:29

to diarrhea and possibly constipation

play07:32

genotoxicity inflammation and also

play07:36

altered mucosal integrity

play07:40

challenges with breath testing still

play07:42

remain

play07:43

for example Rapid Transit how quickly

play07:46

food in this case sugar moves through

play07:49

your small intestine may give false

play07:51

positives for instance if the lactulose

play07:54

sugar moves too quickly through the

play07:55

small intestine it ends up measuring

play07:58

colonic fermentation instead of sibo

play08:02

also there's a question about the

play08:05

ability of breath testing to accurately

play08:08

diagnose sibo when there's very few

play08:10

bacteria present as little as 10 to the

play08:13

three that's a thousand bacteria per ml

play08:15

is technically positive for sibo but can

play08:19

such a small number of bacteria produce

play08:21

measurable amounts of these gases in the

play08:24

breath test

play08:26

also keep in mind that sibo is only one

play08:29

of several forms of dysbiosis being sibo

play08:32

negative does not necessarily exclude

play08:35

the possibility of other forms of

play08:37

dysbiosis including small intestinal

play08:39

fungal overgrowth

play08:41

cfootestinal methanogen overgrowth IMO

play08:44

or even large intestinal bacterial

play08:46

overgrowth olibo as well as significant

play08:49

imbalances in individual strains in your

play08:52

gut could be the cause of your symptoms

play08:55

additional tests to consider would sibo

play08:57

include a comprehensive blood test

play09:00

comprehensive stool tests and in some

play09:02

cases endoscopy and colonoscopy

play09:06

okay what are the treatment options for

play09:09

sibo

play09:11

unfortunately the most common treatment

play09:13

is antibiotics a class of drugs that

play09:15

I've researched and developed when I was

play09:17

in Fama

play09:18

the top two antibiotics for sibo or

play09:20

rifaximin approved for ibsd a

play09:23

sibo-related condition mostly to address

play09:25

hydrogen producing bacteria and then a

play09:28

combination of rifaximin with neomycin

play09:31

for constipation to address both sibo

play09:34

and the intestinal methanogen overgrowth

play09:37

it's reasonable to think that sibo is an

play09:40

infection and therefore something that

play09:42

needs to be killed

play09:44

antibiotic treatment is based on this

play09:46

notion

play09:47

but we should keep in mind that sibo

play09:49

arises primarily from bacteria and our

play09:51

own large and small intestine

play09:54

these bacteria are part of our commensal

play09:56

population

play09:57

they play an important role in nutrition

play10:00

immunity bile acid levels appetite

play10:03

regulation fat storage and protection

play10:06

from True pathogens

play10:08

so keeping them contained in balance in

play10:12

the right place instead of Killing Them

play10:14

seems like the best strategy

play10:17

also we don't want to kill off

play10:19

indigenous small intestinal biotolerant

play10:22

bacteria that have an important role in

play10:25

digestion and health

play10:28

now antibiotics can be useful when your

play10:31

symptoms are severe for instance if you

play10:33

become malnourished experience

play10:35

significant weight loss or have other

play10:37

serious symptoms or sibo-related health

play10:39

issues

play10:41

antibiotics won't work in all cases but

play10:43

they'll often reduce the overgrowth

play10:46

improve symptoms and help restore small

play10:49

bowel function

play10:51

unfortunately antibiotics do not address

play10:53

the underlying causes and without that

play10:55

sibo or IMO or other forms of dysbiosis

play10:58

will likely come back so with or without

play11:01

antibiotics the underlying cost piece

play11:03

must be part of the overall treatment

play11:05

strategy

play11:07

another challenge with antibiotics is

play11:09

that they're not as effective as you

play11:11

might think

play11:12

many intestinal bacteria are resistant

play11:14

or tolerant to antibiotics regarding

play11:17

rifaximin a 2016 study showed that 64

play11:21

percent of sibo-related ibsd patients

play11:23

relapsed and required a second treatment

play11:26

and retreatment was only 6.6 percent

play11:29

more effective than placebo

play11:32

now at least rifaximin is one of the

play11:35

safer antibiotics because it stays

play11:37

mostly in the intestine minimizing

play11:39

systemic reactions and the same is true

play11:42

for neomycin moving to more powerful and

play11:46

systemic antibiotics increases the risk

play11:48

of side effects including clostridious

play11:50

difficile infection allergic reactions

play11:53

and bacterial resistance which renters

play11:56

it renders antibiotics less effective

play11:58

for fighting serious infections in the

play12:00

future

play12:01

how about herbal antimicrobials

play12:04

many herbal extracts are known to

play12:06

possess antimicrobial activity based on

play12:09

testing in the lab with a test tube but

play12:12

this activity has not been confirmed in

play12:15

well-controlled human trials also

play12:17

individual herbal extracts tend to be

play12:19

less potent than synthetic antibiotics

play12:21

and that's why they're often used in

play12:23

combination including things like

play12:25

Allison berberine oregano oil and Neil

play12:27

in combinations

play12:29

while a variety of these extracts have

play12:31

been proposed for sibo treatments

play12:33

there's not much published literature

play12:36

on the efficacy a small study in 2014

play12:40

found that a combination of herbal

play12:42

antibiotics

play12:44

was at least as effective as rifaximin

play12:46

but we need more definitive studies to

play12:49

confirm these results and off also keep

play12:52

in mind that rifaximin was only 10

play12:54

percent better than Placebo in the study

play12:57

used to get FDA approval

play13:00

now what about probiotics you may have

play13:02

heard that sibo patients should not take

play13:04

probiotics because why would you add

play13:07

more bacteria when you already have an

play13:09

overgrowth

play13:10

well probiotics are not a Panacea some

play13:14

may be helpful based on some studies

play13:16

there's a few that come to mind in a

play13:19

2016 study a combination of

play13:21

bifidobacterium bifidum lactobacillus

play13:24

acidophilus and streptocalis and GI

play13:27

cancer patients with sibo showed that

play13:29

sibo was resolved in 81 percent of the

play13:32

treatment group compared to 25 percent

play13:34

in the placebo group

play13:36

a 2014 study looking at a probiotic

play13:40

containing a combination of

play13:41

bifidobacterium and lactobacillus

play13:43

strains along with strep thymophilus

play13:45

resolve sibo and 24 of liver disease

play13:49

patients in the treatment group but none

play13:52

in the control group

play13:54

a 2020 study of saccharomyces bellate

play13:58

with the antibiotic metronidazole given

play14:01

Alona together to systemic sclerosis

play14:03

patients for two months showed that

play14:05

Escalade resolves C bone 33 percent of

play14:08

the patients compared to metronidazole

play14:11

which resolve sibo and 25 percent of the

play14:13

patients together the results were

play14:15

additive in other words over 50 percent

play14:18

which might suggest that each works by a

play14:20

different mechanism

play14:22

a 2009 report on 40 sibo patients with

play14:27

diarrhea and other symptoms that were

play14:30

given bacillus clausiai for one month

play14:33

they reported a 47 percent sibo

play14:36

eradication rate

play14:38

keep in mind this was a letter to the

play14:40

editor not a full-blown publication so

play14:43

the details were a little Limited

play14:45

a study on 20 patients with constipation

play14:48

right I'm ontestinal methanogenovo

play14:51

growth showed that lactobacillus rooteri

play14:54

given for four weeks significantly

play14:57

improved weekly bowel movements and

play14:59

reduced methane levels

play15:01

now while probiotics can be helpful some

play15:05

people may experience symptoms such as

play15:07

loose stools bloating abdominal pain

play15:09

particularly when they first start

play15:11

taking them

play15:13

let's talk about other dietary

play15:14

supplements

play15:16

a variety of dietary supplements are

play15:18

promoted for treating sibo and some of

play15:20

them can be quite helpful here's some

play15:23

examples a multivitamin with minerals to

play15:26

address address nutritional deficiencies

play15:29

digestive enzymes with or without bile

play15:32

salts to improve digestion

play15:34

and by the way improved digestion limits

play15:37

the fuel for sibo

play15:39

betaine HCL and sublingual B12 if you

play15:43

suspect you have low stomach acid also

play15:45

see my video on IU at risk for low

play15:47

stomach goes through stomach acid goes

play15:50

through the risk factors and of course

play15:52

you always want to get to the bottom of

play15:54

why do I have low stomach acid in the

play15:56

first place and address the cause

play15:58

L-glutamine zinconazine and acetyl

play16:01

cysteine these are some of the

play16:03

supplements that have been proposed for

play16:06

mucosal lining support integrity and

play16:10

potentially for antibiofilms

play16:13

antibiofilm agents are mostly enzymes

play16:16

and they're effective at disrupting

play16:19

biofilms in the laboratory but there's

play16:22

limited data to show that they work in

play16:24

patients

play16:25

it's true that most of our microbes in

play16:27

fact most microbes on the planet exist

play16:29

in biofilms but most of these are

play16:32

healthy biofilms so disrupting biofilms

play16:35

in the gut is at the very least a little

play16:37

bit questionable I can see these for

play16:40

invasive biofilms like what you get in

play16:42

wounds and or what is seen in colon

play16:44

cancer but on the mucosal surface we

play16:47

have this mucus that can be sloughed off

play16:49

to take care of biofilms on its own so

play16:51

it's a question of whether we need

play16:53

additional help there or not

play16:59

there's five things to keep in mind when

play17:01

taking supplements

play17:03

one make sure that you're not taking

play17:06

toxic levels of certain vitamins or

play17:08

minerals for instance a d e B6 zinc iron

play17:12

and calcium are some that can be toxic

play17:15

consider that some supplements can

play17:17

impact other medications you might be

play17:19

taking and three make sure they don't

play17:22

contain excess fermentable carbohydrates

play17:24

which can further fuel sibo

play17:27

most supplements are meant to be taken

play17:29

for weeks to a couple of months

play17:31

long-term use may carry health risks

play17:34

because there's no studies that will

play17:36

show what happens after taking them a

play17:38

long time number five read up on all

play17:41

possible health risks and and side

play17:44

effects before taking them look at the

play17:46

labels carefully again supplements can

play17:49

be quite helpful when used judiciously

play17:51

but over supplementation is common and

play17:54

unfortunately it can complicate things

play17:55

in treating sibo

play17:57

so I'm very careful when evaluating and

play18:00

recommending specific supplements to my

play18:02

clients as part of my consultation

play18:03

program

play18:06

finally let's talk about diet

play18:09

last but not least your diet and dietary

play18:12

behaviors are two of the most important

play18:14

factors along with identifying and

play18:17

addressing underlying causes

play18:19

the pervasive view on diets for sibo is

play18:22

that sibo diets only address the

play18:24

symptoms

play18:25

but the symptoms are not just floating

play18:27

out there in space they're being caused

play18:29

by something a few years ago I gave a

play18:31

talk at sibocon and it was focused on

play18:33

this exact point for more information

play18:35

you can watch that presentation on this

play18:37

channel

play18:38

my conclusion was that diets that limit

play18:41

specific carbs or overall carbohydrates

play18:44

are effective at resolving symptoms but

play18:47

they also reduce intestinal gases short

play18:50

chain fatty acids they restore pH

play18:53

balance and they address dysbioses and

play18:56

sibo-related conditions including IBS

play18:59

obesity and epilepsy

play19:02

and views on science-based diets are

play19:04

changing for instance 91 percent of 1500

play19:07

gastroenterologists

play19:09

believe that diets are as good or better

play19:12

as medical therapies for IBS this was

play19:15

based on a survey conducted in 2018.

play19:18

in the past many of the symptoms we now

play19:20

associate with sibo were recognized as

play19:23

carbohydrate intolerance sound familiar

play19:26

this is an important point because

play19:28

carbohydrate intolerance is a form of

play19:30

malabsorption that can lead to dysbiosis

play19:33

and help feed sibo for instance lactose

play19:36

intolerance it's very common in sibo

play19:38

patients and it's been recognized for

play19:40

over a century

play19:41

while fructose intolerance which is also

play19:44

linked to sibo was first documented in

play19:46

the 70s

play19:47

recently sugar alcohols except for

play19:50

erythritol as I've talked about before

play19:52

and dietary fiber intolerances have been

play19:55

added to the list

play19:56

and I make a case in the fast track

play19:58

digestion books that resistant starch

play20:01

is related to dietary fiber and should

play20:04

also be limited for sibo and other

play20:06

conditions involving carbohydrate

play20:08

intolerance

play20:10

according to the Merck Manual the

play20:12

standard treatment for carbohydrate

play20:13

intolerance is to limit the offending

play20:15

species of carbohydrate this simple

play20:18

conclusion is supported by the textbook

play20:20

a primary and acute care medicine

play20:23

which states that dietary alterations

play20:25

that to reduce intestinal gas a hammock

play20:28

of sibo require the reduction of lactose

play20:32

fructose certain oligosaccharides

play20:34

resistant starch fiber and sugar

play20:36

alcohols

play20:37

this is precisely the group of

play20:39

carbohydrates that the fast track diet

play20:41

limits

play20:43

the very same recommendations for IBS

play20:45

are also found in the nice European

play20:48

guidelines and these are based on

play20:50

Cochrane reviews and other published

play20:52

literature

play20:54

Mike Sweeney a dietitian in the UK and

play20:57

his colleagues used the fast track diet

play20:59

for their IBS patients and reported its

play21:02

Effectiveness in his service evaluation

play21:05

and you can see a link to the uh the

play21:08

transcript video of this evaluation

play21:11

there's also a pilot study it's still in

play21:14

the pre-print stage demonstrating the

play21:17

effectiveness of the carnivore diet in

play21:19

resolving sibo

play21:21

and finally the elemental diet which

play21:24

eliminates all complex carbs is quite

play21:27

effective at addressing sibo

play21:30

now regardless of whether you take

play21:32

synthetic antibiotics or antimicrobial

play21:34

herbs a diet that limits fermentable

play21:37

carbohydrates is required for addressing

play21:40

sibo and once your symptoms are fully

play21:43

resolved then you can experiment with

play21:46

reintroducing certain carbohydrate

play21:48

species slowly and safely as your

play21:51

digestion improves

play21:54

to pull this all together

play21:56

all four elements I talked about can

play21:58

play a role in addressing sibo for

play22:01

serious cases of sibo with nutritional

play22:03

deficiencies antibiotics may be

play22:04

recommended and appropriate but for

play22:07

fully addressing sibo and preventing

play22:09

recurrence there's three key elements

play22:11

that can't be ignored

play22:13

one do everything you can to identify

play22:17

and address the underlying cause or

play22:19

causes which will vary from person to

play22:22

person and there is a total of at least

play22:24

25 or 30 possible underlying causes

play22:28

on this topic a chapter in the

play22:30

fast-track digestion books will be

play22:32

helpful

play22:33

some examples include pancreatic

play22:35

insufficiency antibiotics bile acid

play22:38

issues right too much or too little or

play22:41

excessive bile deconjugation by certain

play22:43

bacteria

play22:46

resulting in poor reabsorption of the

play22:48

bile acids brush border enzyme

play22:51

deficiencies

play22:52

Villi damage low stomach acid and

play22:56

anything that alters motility including

play22:58

GI infections medications excessive

play23:02

methane levels

play23:03

Scleroderma surgery adhesions diabetes

play23:08

Etc

play23:09

number two limit fermentable

play23:11

carbohydrates in your diet but

play23:13

particularly lactose fructose resistant

play23:16

starch fibers and sugar alcohols

play23:19

you want to match your diet with your

play23:22

ability to digest and absorb the

play23:24

nutrients

play23:25

particularly carbohydrates sibo bacteria

play23:28

depend on carbohydrates is the primary

play23:30

fuel source either directly or is

play23:34

Downstream byproducts of fermentation

play23:36

for instance the methanogens sulfate

play23:39

reducing bacteria use hydrogen produced

play23:42

from the primary fermenters

play23:44

number three

play23:46

incorporate pro-digestion pro-absorption

play23:49

behaviors and practices

play23:51

this area is often overlooked but plays

play23:54

a critical role in addressing sibo and

play23:56

other forms of dysbiosis how are you

play23:59

selecting your foods and how are you

play24:01

preparing them how are you storing them

play24:03

and importantly how are you consuming

play24:05

them do you leave spaces between your

play24:07

meals do you eat slowly and chew well do

play24:11

you have a fast

play24:12

and what's your approach to Breaking

play24:14

fast what dietary supplements have you

play24:17

tried aimed at improving digestion each

play24:20

of these three elements of features of

play24:22

the fast track diet for more information

play24:24

about the diet system you can read the

play24:26

fast track digestion IBS book there's

play24:29

also one on hotburn or you can use the

play24:32

fast track diet mobile app for

play24:34

implementing the diet

play24:35

for questions and support you can join

play24:38

the fast track diet Facebook group and

play24:40

for individual consultation you can

play24:43

contact me through

play24:44

digestivehealthinstitute.org

play24:47

thank you for watching if you like this

play24:49

video please share and subscribe and

play24:51

I'll see you next time

Rate This

5.0 / 5 (0 votes)

Étiquettes Connexes
SIBO treatmentdigestive healthgut bacteriadiet solutionsantibiotic alternativesSIBO symptomsintestinal healthautoimmune conditionsdigestive disordersdietary guidelines
Besoin d'un résumé en anglais ?