Capítulo 5 de Cell at Work de la primera temporada subtitulado al español

Summary

This script takes place inside the human body, where various cells like T cells, macrophages, and memory cells work to combat invading allergens like cedar pollen. The immune response, including histamine release, causes familiar allergic reactions like sneezing, nasal congestion, and inflammation. Despite these cells following their biological duties, the allergic response spirals out of control. Eventually, a powerful intervention by steroids calms the immune system, suppressing the allergic symptoms. The narrative highlights the body’s defense mechanisms, teamwork among cells, and the role of medications in managing allergic reactions.

Takeaways

• 😷 The human body contains approximately 37 trillion cells that work tirelessly 24/7 to keep us healthy.
• 🛡️ Helper T-cells are like strategic commanders that receive notifications of external threats and decide on a plan to attack the invaders.
• 🌪️ Pollen, specifically cedar pollen, is highlighted as a common allergen causing issues during its peak season in March.
• 🤧 The script humorously describes the body's immune response to allergens, including the overreaction that can lead to allergy symptoms.
• 🔍 Macrophages are introduced as cells that engulf and break down bacteria and foreign substances, playing a crucial role in the body's defense.
• 🚨 The body's immune system is depicted as a complex network of cells that communicate and react to threats, sometimes causing more harm than good.
• 🌟 Memory cells are mentioned as lymphocytes that remember antigens from past infections to mount a faster response upon re-exposure.
• 🌊 The script uses the metaphor of a 'great disaster' to describe an overwhelming immune response, emphasizing the body's ability to adapt and recover.
• 💊 Steroids are introduced as a medical intervention with potent anti-inflammatory and immunosuppressive effects to control severe allergic reactions.
• 🌈 The narrative concludes with a resolution of the allergic symptoms, highlighting the body's resilience and the importance of balance in the immune response.

Q & A

How many cells are there in the human body according to the script?

The script mentions that there are approximately 37 trillion cells in the human body.

What is the role of Helper T cells in the immune system as described in the script?

Helper T cells receive notifications of external invasions and use information about the nature of the enemy to strategize and enable precise attacks on the invading pathogens.

What does the script suggest about the increase in cedar pollen during the peak season?

The script implies that during the peak season in March, the amount of cedar pollen increases, which is not unusual for this time of year.

What is the function of mast cells in the body as mentioned in the script?

Mast cells, when stimulated by an excess of IgE antibodies, secrete chemicals like histamine and leukotrienes, contributing to allergic reactions.

How does the script describe the role of B cells in the immune response?

B cells, referred to as antibody-producing cells, create antibodies to fight against antigens like bacteria and viruses.

What is the script's explanation of the term 'mast cells' and their relation to obesity?

The script clarifies that 'mast cells', despite their name, are not related to obesity. They are cells that secrete substances like histamine in response to the presence of allergens.

What is the effect of histamine on the body as described in the script?

Histamine increases the permeability of blood vessel walls, allowing white blood cells to become more mobile, and can cause symptoms like sneezing, nasal congestion, and itchy eyes.

What is the role of eosinophils in the context of the script?

Eosinophils are a type of white blood cell that play a role in combating parasitic worms and are also involved in allergic reactions.

How does the script describe the process of an allergic reaction?

The script describes an allergic reaction as a process involving the release of histamine and other chemicals, leading to symptoms like a runny nose, sneezing, and itchy eyes.

What is the significance of the 'Steroids' mentioned in the script?

Steroids, also known as corticosteroids, are mentioned as having potent anti-inflammatory and immunosuppressive effects, which help to suppress the symptoms caused by histamine and alleviate allergic reactions.

What is the script's mention of the side effects of steroids?

The script cautions that long-term or high-dose administration of steroids can lead to side effects, emphasizing the importance of proper dosage and duration.

Outlines

00:00

🔬 Immune System Battle

This paragraph describes the human body's immune system, highlighting the continuous work of approximately 37 trillion cells. It introduces the T-cells as strategic commanders that receive alerts about external threats and devise strategies to attack invaders. The script also humorously mentions an allergy to cedar pollen, a common issue in Japan during spring, and how the body's cells might react to such an allergen. It ends with a playful countdown, suggesting an imminent allergic reaction.

05:01

🌿 Cedar Pollen Allergy

The script discusses the role of various immune cells, such as red blood cells, macrophages, and white blood cells, in dealing with allergens like cedar pollen. It explains how these cells work to engulf and break down foreign substances. The paragraph also touches on the concept of memory cells, which remember past antigens to mount a quicker response to future infections. The narrative includes a dramatic and humorous portrayal of an allergic reaction, with cells expressing concern about an impending 'disaster'.

10:03

🤧 Allergic Reactions

This section delves into the specifics of an allergic reaction, focusing on the role of mast cells and the release of histamine. It explains how histamine causes inflammation and other symptoms typical of allergies, such as sneezing, nasal congestion, and itchy eyes. The script uses a storytelling approach to describe the cells' interactions and their attempts to manage the situation, emphasizing the overproduction of IgE antibodies and the subsequent allergic response.

15:05

💊 Steroid Intervention

The paragraph introduces the use of steroids to combat the symptoms of an allergic reaction. It describes how steroids have potent anti-inflammatory and immunosuppressive effects that can effectively reduce the symptoms caused by histamine. The script personifies the steroid as a powerful agent that can quell the allergic response, but also cautions about the potential side effects of long-term or high-dose steroid use.

20:05

🌟 Resolution and Memory

The final paragraph wraps up the narrative by showing the resolution of the allergic reaction. It suggests that with the help of the steroid and the natural decline of allergens, the body's cells have reached a state of peace. The script also hints at the importance of memory in the immune system, as cells prepare to remember this experience for future reference. The ending is optimistic, with a sense of relief and a look towards the future.

Keywords

💡T-helper cells

T-helper cells are a type of immune cell that coordinates the body's immune response by directing other immune cells to attack invading pathogens. In the video, they are described as receiving information about external invaders and formulating an attack strategy. This concept ties into the immune system's complex mechanisms for defending against threats like allergens.

💡Allergen

An allergen is a substance that can cause an allergic reaction. In this video, the allergen specifically mentioned is 'cedar pollen,' which triggers an immune response in the body. Cedar pollen is depicted as a foreign invader, and the immune cells react to it, causing symptoms like inflammation.

💡Histamine

Histamine is a chemical released by mast cells (also called 'fat cells' in the video) in response to allergens. It causes various allergic symptoms like inflammation, itching, and sneezing. The video highlights the role of histamine in causing the typical allergy symptoms associated with cedar pollen.

💡B-cells

B-cells are a type of white blood cell that produces antibodies to fight off pathogens. In the video, B-cells are portrayed as producing IgE antibodies in response to allergens like cedar pollen, which is crucial for understanding the allergic reaction depicted.

💡IgE antibodies

IgE antibodies are specific antibodies that play a critical role in allergic reactions. The video emphasizes that excessive production of IgE antibodies, stimulated by allergens like cedar pollen, leads to the release of histamine and triggers allergic symptoms such as sneezing and inflammation.

💡Mast cells

Mast cells, also referred to as 'fat cells' in the video, are immune cells that release histamine in response to allergens. When IgE antibodies bind to allergens, mast cells are activated, releasing histamine and causing allergic symptoms like inflammation. They are a key component of the body's immune response to allergens.

💡Steroids

Steroids, particularly corticosteroids, are anti-inflammatory drugs used to suppress immune responses. In the video, a character representing steroids arrives to calm the immune overreaction caused by the cedar pollen. Steroids are portrayed as powerful agents that can significantly reduce allergic symptoms by controlling inflammation.

💡Macrophage

Macrophages are immune cells that engulf and digest pathogens and foreign particles. In the video, they are referred to as 'phagocytes,' which are responsible for breaking down allergens like cedar pollen. Macrophages are part of the body’s first line of defense and help clean up after the immune response.

💡Memory cells

Memory cells are a type of lymphocyte that remembers past invaders, enabling the immune system to respond more quickly upon re-exposure. In the video, the 'memory cell' character recalls past encounters with the cedar pollen allergen, suggesting that the immune system is prepared to react to familiar threats.

💡Allergic reaction

An allergic reaction is the immune system's overreaction to harmless substances like pollen. In the video, the body’s exaggerated response to cedar pollen is depicted through various immune mechanisms, including the release of histamine, leading to symptoms like sneezing, inflammation, and mucus production.

Highlights

Human body contains approximately 37 trillion cells working tirelessly 24/7.

T-cells are alerted to external invasions and strategize to attack the intruders.

Cytokines play a role in coordinating immune responses.

Allergens from cedar pollen can cause allergic reactions even though they are not pathogens.

Macrophages and dendritic cells are involved in engulfing and breaking down foreign substances.

The immune system sometimes overreacts to harmless substances like pollen.

Histamine is released by mast cells, causing allergy symptoms such as sneezing and runny nose.

Eosinophils are part of the immune response to allergens.

Memory cells remember past antigens to respond more effectively to future encounters.

B cells, also known as antibody-producing cells, fight against antigens like bacteria and viruses.

The body's immune response can sometimes be too strong, leading to inflammation and discomfort.

Steroids are introduced as a powerful anti-inflammatory and immunosuppressive medication.

Allergies can be seasonal, with pollen being a common trigger in spring.

The immune system's complex dance involves various cells working together to protect the body.

Allergic reactions can cause a range of symptoms, from mild discomfort to severe reactions.

The body has a remarkable ability to adapt and respond to allergens over time.

Steroids can have side effects if used long-term or in large amounts.

The importance of balance in the immune response is highlighted, as overreaction can lead to unnecessary suffering.

The narrative ends with a resolution of the allergic reaction and a return to normalcy.

Transcripts

[音楽]

ん

[音楽]

yeah

人間は体の中には約37超2000億個もの細胞たちが毎日毎日24時間365日元気

に働いています

[音楽]

人間ならかっ

目標接近中ですー

[音楽]

9キロ指示をボクスタースタンじゃあマイクラない

接触まであと20秒19

18

wh

ヘルパー t 細胞外的進入の知らせを受け

外敵がどんなものであるのかという情報をもとに侵入した敵に的確に攻撃できるように

戦略を決める司令官

誰かうん

[音楽]

してしまった

スギ花粉がんっ

スギ花粉スギは花粉を風に乗せ

遠距離に飛散させるピークはに3月

今年もおっ

yeah

ええええええ

ane 4 d 2

mar

今日もはく冬33と半裸立の過ぎから墨会だけ

廣瀬麻伊細いゴッキー助けされてる方が来たあああ

me

ani

[音楽]

今日も雑記見合い所ファイトさあいきん梅雨せて5 year

あって対2月ガユスギュとフードフェスとラフなあたら鎖棒

ni

[音楽]

amaran

ani

ni

ni

me

[音楽]

aname

eno

ana

penang

me

me

[音楽]

ana

daniele

すぎか free

[音楽]

いっ

うまくに何かがあった

注ぎ方に

ヘルニャー荒れる民家は免疫反応が特定のゲーム2に関して過剰に行うこと

緩急粘膜好きの枕カバーしおり号検定じゃん

お茶もこぼれちゃうシーン

持って言わ

りつさんご計50地点に複数のか3着スイ風

まばたきが間に合わなかったとかこのままなどが荒れる元たちなハイセイコーから絶え

ないや侵入しますよ

ちょすぐ ko を流すんだ

[音楽]

49年バックスキンの職員の方区

お気を付け下さいません

ハイシー小倉外敵の侵入したため

眼球年バック付近の職員の方々は

ゲームお気を付け下さい

[音楽]

快適

いやだなあこの近くだ

早くこの仕事を済ませちゃおっと

ねえ皆になる

届け席満州所バックっています

現在1544スーッとあれだを捻る自分

こっちねー

すぅいー

[音楽]

なにこれ

aname

nan

rar

攻撃ハズレん

いいいいいい

me

バッハを

赤血球か大丈夫かはいっ

ありがとうございます

a 棟これ一体何なんですすぎとか言ってましたけどこいつかあぁそう

とにかくくればんっああ

食作用食細胞と呼ばれる探求やマクロファージ

白血球頭が細菌や異物を細胞内に取り込み

分解すること貪食ともいうこの味はは

スギ花粉から出てきたアレルゲンだな今の時期なら珍しくもない

図体はでかいが細菌やウイルスとは違って病気の原因になったりもしない

そうなんですねまあそれでも何かしらトラブルの原因にはなるからなぁ

殺すのが決まりなんだなうそっかごめんね

すぞまさかスギ花粉のアレルゲンじゃないかー

カッター粘膜の排水溝から入り込んだってのはそいつだったカーン

くれジャンまるでいい伝えた

お前をあー椅子0俺は記憶細胞だ

記憶細胞抗原の免疫を記憶しているリンパ球同じ細菌やウイルスのサイドの審議に唱え

ている

何を慌ててるんだ

すぎアレルゲンは危険な高原ではないだろ

まだ今だ

ダガー

俺たち極細胞に代々伝わる言い伝えがあるんだ

2ためどんな内容なんだ

pa

記憶細胞さんはぁんっ

ん

俺たち記憶細胞に代々伝わる言い伝えがあるんだ

宇宙より災いの隆盛平井せしとき山はいかに大地は荒ぶり

海はうごめくどういう意味ですか

2

[拍手]

住まい大噴火地殻変動第構図が一気に起こる

未曾有の大災害に見舞われる

[音楽]

どういっそ位5位

pon

彼がそうへい

今には客数

ていません

方以外のシーンでした

tar

ああああああ

me

なんだこれ大量のすぎる

me

[拍手]

b w h

rar

んづぎ w エネルギー緊急対策音大状況報告してください

おっ犬は段丘面も付与パーティーし開けすぎあバルダーノ被害報告がツールズけど

ああっなんかこいつら毎年来る数が増えてってない

いいんだけどさこっちは秘密行きアルシェ

秘密兵器というと

最後のことですねその通り早速現場に向かうて止まれ

お前がニューとけ赤血球

ああああああ

が収まる気配がないよ

まさか本当に題材が4枚目

in 任せてください

toni

b 細胞抗体産生細胞と呼ばれている細菌やウイルスなどの抗原に対し今たいという

武器を作り戦うリンパ球の一種

ベール5 oo

清く細胞

その大災害っていうのは事前に防げないのか

数なるきりが地上つつ

それが地獄への扉を100のド級にエロスいいいいいい

moon

amaran

nan

[拍手]

ああああああ

サーキットだ聖なる聞いて ige 抗体どころか

なんかアイツのおかげで解決そうだけどだぞ

今はなこれからもっとひどいことが起こるんだよって切りは運となり大雨を読んで

すべて多し流すぞ

左が起こるかわかんないけどな役はイだろうめちゃぜたり

にゃんすごい事が起こるんだよん

何が起こるのか全然わからんばそれは

か

涙道 p サイダー

[音楽]

どっから

えっ

なにこの数値

働く細胞

働く際バー

なんなのこの大量の ig 使用家はどうなってるの

痛い

今の数値は土砂初めてだろう

マスト細胞肥満細胞とも呼ばれている

過剰に作られた ig の刺激に反応して

ヒスタミンやロイコトリエンなどの化学物質を分泌する

肥満細胞といっても肥満とは関係ない

[音楽]

でも ig の量に応じたヒスタミを出せって書いてあるし

うーん4

[音楽]

ok ちょっと待っていった落ち着か

営巣大丈夫よやればできる

焦りの禁物よマニュアルどおりにやればいいの

それが私も仕事なんだから

このくらいかなぁ

とにかく ige 抗体の使いすぎはなんていうかよくないんだ

おいされた

t 細胞それあまり対応に使わない方が良さそうだぞ

よくわからないけど一体がねぇイースト a

大丈夫ですよそんなまあどのみち心配ないっせん俺そろそろヒスタミンが科されますよ

あれで炎症を起こしてアレルゲンを排除するんです

なんかお引越んですよ

ノズルを変えるんだろうきっと

ヒスタミン異物や組織の損傷認識したマスト細胞などから分泌される

化学伝達物質

car

cue

当スレ ana

次から次へとポイズン

あーすぎアレルゲンがこんなに入ってきてるから交代の使用値が高かったんだね

ダイヘンじゃ1歳0もっといっぱいだったらきゃー

これが井戸の題材がキャー違う

今バロック序の口に過ぎない本当にヤバイのはこれじゃああー

ヒスタミンの働きヒスタミンは血管内皮細胞の間隔を広げ白血球等の郵送性を高める

働きがある

is he

喫茶リーガーする近くから5度良い何と目下千田

は最後に入れる2はそれが過ぎアレルゲンを排除するため

止めるわけにはいかないとバキュンだーぞ

パパ電話

大丈夫きっと耳が折れた

大変ですか所今度はなんちゃえええ

うんキス中枢がイカれたセレでね月給4免疫システムが罰通してしまいがある

うーんいい

うち給与3キスってるかどうかって

par les

me

[音楽]

wh

暮れゆくん

ni

三味ヒスタミンの鼻の粘膜にあり知覚神経を刺激する

この刺激がくしゃみ中枢見たするとくしゃみを連発してしまう

19 h

鼻づまりヒスタミンが鼻の粘膜にある血管に作用して炎症などを引き起こすその結果

鼻の粘膜が腫れてむくみ鼻づまりの起こる

ni

use

涙

ヒスタミンが目の知覚神経などを刺激して充血やかゆみなどの炎症を引き起こす

涙も必要以上に出る

[音楽]

1回 reg

[音楽]

次か相愛

にっ

花粉が高原となって起きるくしゃみ鼻蜜

鼻づまり目のかゆみなどのアレルギー症状

[拍手]

[音楽]

胸式小屋かねええええ

が原因だ

をしてくれるんだ底材棒

どうぞお前がこうだよ神奈川使うから独歩の俺の体じゃないよ

悪いのはヒスタミンだろ心

re

dai

ああああああ

骨積んだよ話して触ってよ私のせいじゃないは ig が現用

いいやー絶対ヒスタミンの脱水が原因だねぇ

私マニュアル通りに仕事しただけだもん芸名の生ダコんやろ

マニュアル通りの仕事しかできないのかよ p まず相棒

ヌーその名前で呼ばない0 b 細胞のピザバーガードビーでしょ

なんだろてねー

parker パーカーやるかこの

収拾つかなくなってきたああ

しかし

それぞれが自分の仕事を全うしただけならいい

こんなことになってしまうとか

そうなることがわかっていれば

いや

分かっていても

やるしかなかったなぁ

[音楽]

どんな事情があろうと

職務放棄は許され

それが米立つレースくれ

市久米邸

滑るん

h

硫黄すっけくる

あ

やはりそれ

こりゃあ私もよくわかんないんですけどお届け先がここになって

っていうかどっか大騒ぎになってますけど大丈夫ですか

大丈夫安定ばいけない

しかしヨンドクよ

ああああああ

記憶さいろーさんも見たことないものですか桜を見たことがないなぁ

目標地点に到着思っ

[音楽]

[音楽]

おめっなんだれ中から何か

[音楽]

dare

ん

voodoo

th

ああああああ

ん

目標再度た国

愛情します

wh

はあああああ

何万台というなので俺達を襲う

ああああああ

me

愛情します

いもいだサー

聞いたことがあるんだ世界に異変が起こったときにどこからともなく現れる

このタイプはそうに関わった奴らを一掃する約パター

あいつの名はあ

ロイドだ

ステロイド副腎皮質ホルモンとも呼ばれている

強力な抗炎症作用と免疫抑制作用を持つ薬剤

ヒスタミンによって起こった諸症状やアレルギー違反のそのものを強力に抑える

wh

[音楽]

ああああああ

まじゃ絶対長なんかれるわー

rar

すげー推しだけでしが足らずでありああ

私は車

me

[音楽]

ゴリーをありがとうございましたはぁっ

ステロイドが有効成分切れた沈黙してい

なんだかんだでアレルゲンも自然消滅したし

アレルギー反応もう落ち着いただ

みんなも和解できたし

いやー

よかったよかっただ

[音楽]

本当

よかっただ

ステロイドの副作用ステロイドの長期投与や大量投与により副作用が起こる場合もある

両方要領を守ることが大切

[音楽]

これ

今日のことをしっかり記憶しておくよ

[音楽]

君入れ c ベースでされる子よ

[音楽]

遊び

日足あっ tari たんだ

[音楽]

anano cafe はキーが

げっっ

ano hito ni

i was

おいおいきてる

ハッピー ana

[音楽]

ana

ana

ani

saranam

me

na na na na

[音楽]

cl を受けてよ

[音楽]

[拍手]

[音楽]

赤血球は小さい頃どんな月給だったんだ

よく前歯になってました想像でき

次回働く細胞赤芽球と骨全9分

お死後東芝ぞ