Effective Strategies to Manage & Treat PCOS Naturally | PCOS Treatment Guide Pt. 2

Full Episodes
15 Aug 202423:50

Summary

TLDRIn this podcast, Dr. Brendan McCarthy, Chief Medical Officer at ProTA Medical Center, delves into Polycystic Ovary Syndrome (PCOS), focusing on insulin's role and its impact on weight gain. He critiques traditional calorie-cutting approaches, advocating instead for strategies like intermittent fasting to enhance insulin sensitivity. Dr. McCarthy also discusses the importance of micronutrients and his preference for the Whole 30 diet, while cautioning against extreme diets. He introduces supplements like berberine and the off-label use of rapamycin for treating PCOS, emphasizing the need for a holistic and personalized treatment plan.

Takeaways

  • 🌟 Dr. Brendan McCarthy, the chief medical officer of ProTA Medical Center, discusses Polycystic Ovary Syndrome (PCOS) and insulin resistance in detail.
  • 🔍 He emphasizes the importance of understanding insulin's role in PCOS, particularly how insulin resistance can lead to weight gain and other PCOS symptoms.
  • 💉 Dr. McCarthy critiques traditional calorie-cutting methods for treating PCOS, arguing they don't address the root cause of insulin resistance.
  • ⏱️ Intermittent fasting is highlighted as a potential treatment, not for calorie restriction, but to enhance insulin sensitivity and promote autophagy.
  • 💊 Supplements like chromium, zinc, and magnesium are recommended to support insulin resistance, but their effectiveness varies and should be tailored to individual needs.
  • 💪 Rapamycin, an immunosuppressive drug, is discussed as a treatment option that can enhance autophagy and improve insulin receptor function, but its use requires careful dosing.
  • 🥗 A Whole30 diet is advocated as a rich source of micronutrients that can support PCOS treatment, focusing on plant-based calories and avoiding insulin-stimulating foods.
  • 🌿 Berberine, an herb with potential benefits for PCOS, is recommended, with a specific mention of the brand Gaia Herbs for quality assurance.
  • 🌱 Metformin, originally derived from the French lilac plant, is recognized as a plant-based pharmaceutical that can be part of a comprehensive PCOS treatment plan.
  • 📢 The podcast concludes with an invitation for feedback and a teaser for the next episode, which will delve into progesterone as a treatment for PCOS.

Q & A

  • What is the main focus of Dr. Brendan McCarthy's podcast episode on PCOS?

    -The main focus of Dr. Brendan McCarthy's podcast episode is to discuss the role of insulin in PCOS, its impact on weight gain, and various treatment approaches to address the challenges faced by patients with PCOS.

  • Why does Dr. McCarthy consider some diets for PCOS patients as 'barbaric'?

    -Dr. McCarthy refers to some diets as 'barbaric' because they are extremely restrictive and can be harmful to the patient's health, causing unnecessary suffering without effectively addressing the root cause of insulin resistance in PCOS.

  • What is insulin resistance and how does it relate to PCOS?

    -Insulin resistance occurs when the body's cells do not respond properly to insulin, requiring higher levels to function. In the context of PCOS, insulin resistance can lead to elevated insulin levels, which in turn can disrupt hormone balance, leading to symptoms like high androgens, estrogen dominance, and low progesterone.

  • How does intermittent fasting play a role in treating PCOS according to Dr. McCarthy?

    -Intermittent fasting is beneficial for improving insulin sensitivity and resistance in PCOS. It helps by inducing autophagy, a self-cleaning process in the body, which can improve insulin receptor function without necessarily creating a calorie deficit.

  • What is the significance of the mTOR pathway in PCOS treatment as discussed by Dr. McCarthy?

    -The mTOR pathway is significant in PCOS treatment because it is involved in cellular processes like growth and metabolism. Engaging autophagy, which is the natural removal of damaged cells, can be beneficial for PCOS patients, and fasting can help to activate this pathway.

  • Why does Dr. McCarthy emphasize the importance of micronutrients in treating PCOS?

    -Micronutrients are essential for overall health and can play a crucial role in supporting insulin receptor function and hormone balance. Dr. McCarthy emphasizes their importance because they are often lacking in restrictive diets and can help address the underlying causes of PCOS.

  • What supplements does Dr. McCarthy recommend for PCOS patients and why?

    -Dr. McCarthy recommends supplements like chromium, zinc, and magnesium for PCOS patients because they can help support insulin sensitivity and overall hormonal balance. He also advises against generic dosing and emphasizes the importance of personalized treatment based on individual lab results.

  • What is the role of rapamycin in treating PCOS as discussed by Dr. McCarthy?

    -Dr. McCarthy discusses the use of rapamycin, an mTOR inhibitor, in treating PCOS. It can help push the body into autophagy, similar to the effects of fasting, and improve insulin receptor function. However, he cautions that it should be used with care and under medical supervision due to its potential to modulate the immune system.

  • Why does Dr. McCarthy prefer the Whole 30 diet for PCOS patients?

    -Dr. McCarthy prefers the Whole 30 diet because it emphasizes micronutrition through plant-based calories, is rich in micronutrients, and is low on the insulin index. This approach supports overall health and can be more effective in managing PCOS symptoms compared to other diets.

  • What are the potential benefits of berberine for PCOS patients as mentioned by Dr. McCarthy?

    -Berberine is highlighted by Dr. McCarthy as a beneficial herb for PCOS patients due to its potential to improve insulin sensitivity and support overall metabolic health. He specifically recommends the brand Gaia Herbs for its quality and transparency in product labeling.

  • How does Dr. McCarthy view the use of metformin in PCOS treatment?

    -Dr. McCarthy views metformin, originally derived from the French lilac plant, as a plant-based medication that can be part of a comprehensive treatment plan for PCOS. He does not see it as a standalone solution but rather as a component that can work alongside other strategies to address insulin resistance.

Outlines

00:00

🧐 Introduction to PCOS and Insulin Resistance

Dr. Brendan McCarthy, the chief medical officer at ProTA Medical Center, begins the podcast by discussing Polycystic Ovary Syndrome (PCOS) and the role of insulin in the condition. He emphasizes the challenges faced by individuals with PCOS, particularly in managing weight gain that seems resistant to various therapies. Dr. McCarthy shares his experiences from early in his practice, highlighting the ineffectiveness of a 'barbaric diet' he had witnessed. He stresses the importance of understanding insulin resistance as a primary driver of PCOS, explaining how damaged insulin receptors lead to increased insulin levels, which in turn affects hormone balance and contributes to the symptoms of PCOS.

05:01

🕒 The Impact of Intermittent Fasting on Insulin Sensitivity

Dr. McCarthy delves into the concept of intermittent fasting as a method to improve insulin sensitivity in individuals with PCOS. He clarifies misconceptions around fasting, noting that it's not merely about calorie restriction but rather about inducing a state of autophagy, where the body cleanses itself. He discusses the role of mTOR and the benefits of fasting for enhancing insulin receptor function. The doctor also cautions against extreme fasting that could lead to stress and elevated cortisol levels, which may counteract the desired effects on insulin resistance. He advocates for a balanced approach to fasting, tailored to the individual's health metrics such as cortisol, insulin, A1C, and luteinizing hormone levels.

10:01

💊 Supplements and Their Role in Managing PCOS

In this segment, Dr. McCarthy addresses the use of supplements in treating PCOS, expressing caution due to the vast and sometimes misleading market. He specifically endorses chromium, zinc, and magnesium as effective supplements that can support insulin sensitivity and overall health. Dr. McCarthy also touches on the importance of individualized dosing, based on lab results and the patient's unique health profile. He emphasizes the need for a physician's guidance in choosing and administering supplements to ensure safety and effectiveness, rather than self-prescribing based on generic recommendations.

15:03

🍽️ Dietary Approaches to Treating PCOS

Dr. McCarthy shifts the discussion to dietary strategies for managing PCOS, advocating for a diet rich in micronutrients and low on the insulin index. He strongly recommends the Whole 30 diet for its emphasis on plant-based calories and micronutrient availability, and the Mediterranean diet as a close alternative, though noting the latter's need for proper guidance to avoid nutrient-poor choices. The doctor also stresses the importance of a balanced approach to diet, avoiding extreme restrictions that could lead to nutritional deficiencies and stress. He discusses the role of nutrition in repairing insulin receptors and the importance of a supportive and educational approach when guiding patients through dietary changes.

20:04

🌿 Exploring Herbal Remedies and Metformin in PCOS Treatment

In the final paragraph, Dr. McCarthy introduces the use of herbal remedies like berberine, specifically recommending Gaia Herbs for its quality and ethical standards. He also interestingly classifies metformin, commonly known as a pharmaceutical, as an 'herb' due to its origin from the French lilac plant. Dr. McCarthy discusses the importance of using these remedies in conjunction with a comprehensive treatment plan that targets insulin receptors and supports overall health. He concludes the podcast by expressing his passion for his work and the fulfillment he gains from sharing knowledge, inviting listeners to engage with the content and look forward to the next episode where he will discuss progesterone's role in PCOS treatment.

Mindmap

Keywords

💡PCOS

PCOS stands for Polycystic Ovary Syndrome, a hormonal disorder common among women of reproductive age. It is characterized by the presence of multiple cysts in the ovaries, which can lead to symptoms such as irregular periods, acne, and excessive hair growth. In the video, Dr. Brendan McCarthy discusses the challenges of treating PCOS, particularly focusing on insulin resistance as a primary driver of the condition.

💡Insulin Resistance

Insulin resistance refers to a condition where the body's cells do not respond properly to the hormone insulin, leading to elevated levels of insulin in the blood. This is a key concept in the video, as Dr. McCarthy explains that insulin resistance is a primary driver of PCOS and can lead to weight gain and other symptoms. He emphasizes the importance of addressing insulin resistance in treating PCOS.

💡Intermittent Fasting

Intermittent fasting is an eating pattern where individuals cycle between periods of eating and fasting. In the context of the video, Dr. McCarthy discusses how intermittent fasting can be beneficial for improving insulin sensitivity and treating PCOS. He clarifies that the goal is not just calorie restriction but to engage autophagy, a self-cleaning process within cells.

💡Autophagy

Autophagy is a cellular process where cells 'clean' themselves by digesting and removing damaged components. Dr. McCarthy explains that during fasting, the body can enter a state of autophagy, which can improve insulin receptor function and is beneficial for PCOS patients. He stresses the importance of not overdoing fasting to avoid stressing the body.

💡Supplements

Supplements are substances added to the diet to increase the intake of nutrients. In the video, Dr. McCarthy mentions the use of certain supplements like chromium, zinc, and magnesium to support PCOS treatment. He cautions against indiscriminate use and emphasizes the importance of proper dosing based on individual needs and lab results.

💡Rapamycin

Rapamycin, also known as Sirolimus, is a medication that has immunosuppressive properties and is used to prevent organ transplant rejection. Dr. McCarthy discusses its off-label use in treating PCOS due to its ability to target the mTOR pathway, which is involved in autophagy and insulin receptor function. He advises careful dosing to avoid immune suppression.

💡Whole 30 Diet

The Whole 30 Diet is a dietary program designed to reset the body's habits and cravings by eliminating certain foods for a 30-day period. Dr. McCarthy recommends this diet for PCOS patients as it emphasizes whole, unprocessed foods and can improve micronutrition, which is crucial for addressing insulin resistance.

💡Mediterranean Diet

The Mediterranean Diet is a heart-healthy eating plan inspired by the eating habits of people in the Mediterranean region. Dr. McCarthy mentions it as a secondary dietary option for PCOS patients, but he notes that it requires careful guidance to ensure it is followed correctly and does not lead to overconsumption of high-carbohydrate foods.

💡Micronutrition

Micronutrition refers to the adequate intake of essential vitamins and minerals. In the video, Dr. McCarthy stresses the importance of a diet rich in micronutrition for PCOS patients, as it can help repair insulin receptors and address the underlying hormonal imbalances.

💡Berberine

Berberine is a natural compound found in certain plants, known for its potential to improve insulin sensitivity. Dr. McCarthy recommends berberine as a supplement for PCOS patients, specifically citing Gaia Herbs as a reputable source for this supplement. He highlights the importance of choosing high-quality supplements for effective treatment.

Highlights

Dr. Brendan McCarthy discusses the role of insulin in PCOS and its impact on weight gain.

Insulin resistance is identified as a primary driver of PCOS, affecting cellular insulin receptors.

Traditional calorie-cutting methods are critiqued for not addressing insulin resistance in PCOS.

Intermittent fasting is introduced as a potential treatment, with a focus on autophagy rather than calorie restriction.

The importance of not causing stress through fasting and its impact on cortisol levels is emphasized.

Supplements like chromium, zinc, and magnesium are discussed for their role in supporting insulin sensitivity.

Rapamycin is presented as a controversial treatment option for PCOS due to its impact on insulin receptors.

The use of off-label medications like rapamycin is justified with proper patient education and monitoring.

Whole 30 and Mediterranean diets are recommended for their emphasis on micronutrition and low insulin index.

The necessity of a personalized approach to diet, considering individual micronutrient needs, is highlighted.

Berberine, an herb, is mentioned for its potential benefits in treating PCOS.

Metformin, originally derived from an herb, is discussed as a plant-based medication for PCOS.

The importance of not solely relying on metformin and combining it with other treatments is stressed.

The role of a supportive healthcare team, including nutritionists, in guiding PCOS patients through dietary changes is underlined.

Online resources and communities are suggested for patients seeking guidance on dietary changes for PCOS.

The podcast concludes with a teaser for the next episode, which will delve deeper into progesterone's role in PCOS treatment.

Transcripts

play00:08

[Music]

play00:15

hey welcome to my podcast my name is Dr

play00:17

Brendan McCarthy I am the chief medical

play00:19

officer of prota Medical Center in temp

play00:22

Arizona thank you for tuning in uh today

play00:25

we're going to dive deep a little bit

play00:27

more into PCOS and today specifically

play00:30

I'm going to go into the concept of

play00:31

insulin the role that insulin plays in

play00:33

this I want to go into how we would

play00:34

treat this it's all about the weight

play00:37

gain that people have with PCOS that

play00:40

seems to be locked and when they try

play00:43

different therapies nothing seems to

play00:44

work well now some of you yeah you get

play00:47

results with just the basic metform and

play00:49

protocol and some of you yes you get

play00:51

results with intermittent fasting and

play00:53

and those protocols and some of you

play00:55

semaglutide tepati whatever yes they

play00:58

work but the vast

play01:00

majority have challenges I'm here to

play01:03

talk about those challenges and how to

play01:05

approach them and different ways to to

play01:07

look into it and I get results before I

play01:10

get started please scroll down a little

play01:12

bit in here you're going to see there's

play01:14

that section where you're going to say

play01:15

uh subscribe subscribe let me know you

play01:18

like this comment as well I really do

play01:20

appreciate your

play01:21

comments with that said let's get into

play01:24

it I remember in early in practice when

play01:27

I had a patient presenting to clinic and

play01:29

she was seeing being a nutritionist uh I

play01:31

was seeing her for something else and um

play01:34

she had hyperin insulinemia and she was

play01:37

put on this barbaric

play01:39

diet barbaric diet and it was so

play01:43

brutal for

play01:46

PCOS it and it it was sad cuz it just

play01:48

didn't work and she was torturing

play01:52

herself to make it

play01:54

work a lot of you do that I remember I

play01:58

remember it like yesterday you know so

play02:00

many of the things that happened to me

play02:00

in the very early years of my practice

play02:02

shaped me as a physician so many and I

play02:04

go back to that a lot when I do these

play02:06

episodes and these reals I like to show

play02:08

you where I came from you know what

play02:11

formulated this it was very early on a

play02:13

lot of these things that changed me that

play02:15

evolved me and and help me become the

play02:16

doctor I am

play02:18

today are those early years of of

play02:20

experiencing and seeing women

play02:24

suffering no one should be on a barbaric

play02:27

diet I mean if we're desperate and

play02:30

that's all I have

play02:32

okay but there's so much more I can do

play02:35

so what can I do with this what can I do

play02:37

with this PCOS has as a primary driver

play02:42

insulin resistance primary driver

play02:45

primary driver please know this let's

play02:48

talk about that insulin resistance

play02:50

happens when your cell's insulin

play02:52

receptors are not working correctly so

play02:54

the cells need a certain level of

play02:56

insulin receptors and say there's x

play02:59

amount of receptors here and you release

play03:00

a normal level of insulin when you eat

play03:02

your food the insulin then escorts

play03:04

glucose into the cell and there you go

play03:05

you have energy now if the receptors

play03:08

become damaged you're going to need more

play03:09

and more levels of insulin to get

play03:11

glucose in the cell you need to keep

play03:13

increasing output your pancreas keeps

play03:15

making more insulin that elevated level

play03:17

of insulin in your body is necessary to

play03:21

push glucose in the cell over time if

play03:24

you keep having that problem you're

play03:25

going to start seeing your glucose

play03:26

levels go up as well that's a that's a

play03:28

co-actor in this

play03:30

but let's just keep with this if the

play03:32

insulin res receptors are

play03:34

damaged and you have that that damag the

play03:37

insulin receptors going to summon more

play03:39

insulin from the pancreas that insulin

play03:41

sensitive insulin resistance occurs and

play03:42

you're going to see that blood sugar

play03:44

happen and that insulin elevation is as

play03:46

I mentioned the previous episode the

play03:48

thing that drives up and fools around

play03:51

with your your pituitary and that's the

play03:53

thing that drives up your lutenizing

play03:54

hormone which then leads to high

play03:56

androgens leads to estrogen dominance

play03:58

and low progesterone all the things we

play04:00

see with PCOS insulin receptor

play04:02

dysfunction is the first step most

play04:04

important thing we should think about

play04:07

how it's currently treated is just just

play04:09

cut your calories because that's an

play04:11

oldfashioned way of treating that you

play04:12

know it's like well if you have high

play04:14

insulin insulin resistance you high

play04:15

glucose it's because you eat too

play04:17

much a lot of you out there with PCS

play04:20

have normal glucose your glucose is you

play04:23

know 5 54 55 whatever sub 56 you're not

play04:28

pre-diabetic but you have high insulin

play04:31

how is lowering your calories going to

play04:32

repair that it won't repair that it

play04:34

won't repair that but many of you that's

play04:36

all you do cuz you have no other choice

play04:38

you no one ever tells you anything else

play04:40

until today so what do we do what do we

play04:43

do for insulin I wrote this down I

play04:45

sometimes I talk on this I'm like I I

play04:46

forgot to bring this thing up made a

play04:48

list I checked it twice let's first

play04:51

start off with the things that I do that

play04:52

I like that work but may be

play04:54

misinterpreted or misunderstood

play04:55

intermittent fasting timed eating is

play04:58

important for insulin sensitivity and

play05:00

insulin resistance it does help most of

play05:04

you out there would see it through the

play05:05

lens of if I'm going to do intermittent

play05:07

fasting I'm going to starve myself for

play05:09

these amount of hours you start with

play05:10

like I'll do eight hours and then I go

play05:12

to 10 hours I go to 12 hours now I'm 16

play05:14

hours now I'm 18 hours fasting a day and

play05:16

that's going to help me lose weight

play05:17

because I'm not eating during those

play05:18

times so that 18-hour window I should be

play05:20

burning calories and losing weight

play05:21

that's not quite how it works that's not

play05:24

how this will work because that doesn't

play05:27

directly by itself affect the calor

play05:30

restrictive component let me be clear

play05:31

there does not

play05:33

specifically affect the insulin receptor

play05:36

this is very important I word this well

play05:38

I want to do a good job with this when

play05:40

you fast when you fast and you you you

play05:44

pull back on your diet a little bit and

play05:46

you don't eat during a period of time

play05:47

like overnight normally your body goes

play05:50

into something called autophagy where

play05:51

your body just basically cleans itself

play05:53

it's basically cleaning up after itself

play05:55

you know this is It's like a um

play05:57

remodeling redecorations you know that's

play05:59

what's happen happening and and when you

play06:01

have a a a period of time where that's

play06:03

occurring one of the benefits of that

play06:06

during that fasting time one of the

play06:07

things that gets uh uh improved upon are

play06:10

your insulin receptors this has to do

play06:12

something called M tour and I was

play06:14

debating whether I'm going to use the

play06:15

term mour in here and talk about all the

play06:16

weird stuff with that there's enough

play06:18

videos out there enough weird people out

play06:19

there talking about it and and enough

play06:21

like you know um trendy dialogue about

play06:24

but I'm not I don't want to get down

play06:25

into that area I want to be with you in

play06:26

this moment be really clear with you on

play06:28

this just between us when you fast my

play06:31

goal with you is not to really get a a a

play06:33

hypocaloric

play06:35

state because you a lot of you with a

play06:37

lower hemoglobin A1c and your lower

play06:39

fasting glucose you already do that if I

play06:43

have you when you are fasting and you're

play06:45

already doing like you know uh your

play06:47

hemoglobin C say is 5.0 I tell you to do

play06:49

a 18-hour fast what am I doing to you

play06:52

what am I doing to you I'm stressing

play06:53

your body out and what's the stress

play06:55

going to do your cortisol is going to be

play06:56

elevated it's going to be more insulin I

play06:57

didn't solve the problem I didn't solve

play06:59

the problem maybe if I do fasting with

play07:01

them with a calorie deficit concept I'm

play07:04

doing that in order to uh drive down

play07:07

these numbers short term I could and

play07:09

that might work and that's why some of

play07:10

you are like I fasted it used to work

play07:11

but now I gained all the weight back

play07:13

why good question because we created

play07:16

stress with the fast the cortisol the re

play07:19

the the rebound insulin

play07:21

Spike from the stress of fasting too

play07:24

much when your body wasn't ready for it

play07:26

so fasting for the sake of calorie

play07:28

deficit is not working in this it won't

play07:30

work in this I want you to know this

play07:34

it's not the calorie game be with me on

play07:36

that because you you you see your weight

play07:38

is high and you're like it must be me

play07:40

from overeating because the whole world

play07:41

tells you that the world is wrong the

play07:44

world is wrong we are right because I

play07:48

know you know you're not eating a lot

play07:49

when your a and your A1C is is a little

play07:51

like that I know I know I know so what

play07:55

are we going to do when you're inter

play07:57

fast the goal with it is to switch your

play07:59

body into that autophagy that that

play08:02

selfcleaning so I want to get your your

play08:04

your intermittent fasting out a certain

play08:05

period of time where I'm not creating

play08:07

strain in your body and I'm getting the

play08:09

benefit that I'm looking for that's one

play08:10

of the first steps that's important so

play08:12

timed eating no snacking between meals I

play08:14

need as many gaps between meals as

play08:16

possible and I need to make sure you

play08:17

overnight fast for 12 hours and I as

play08:21

your doctor would look at your your

play08:22

cortisol I as your doctor would look at

play08:24

your insulin I as your doctor would look

play08:26

at the A1C I would look at your

play08:27

luteinizing hormone I'm running l to

play08:29

make sure my diet is having impact on

play08:31

you in a positive way but not stressing

play08:33

or straining you if it's not lowering

play08:35

your insulin I'm not doing my job right

play08:38

do you know what I mean it's not working

play08:40

I want it to work so we're going to keep

play08:41

adjusting it what else can I do

play08:44

supplements yeah they they work I get

play08:49

sketchy about supplements because you

play08:52

know there's so much Shenanigans out

play08:54

there about supplements and I'll see Bad

play08:57

actors out there so with piece cosos and

play09:00

with weight and all these things you

play09:02

know there's so many supplements out on

play09:04

the market that are like yeah this works

play09:06

and they're selling you chromium for

play09:07

like a few hundred or something

play09:09

ridiculous because they're trying to

play09:12

trigger your anxiety and your fear and

play09:15

they're trying to trigger that

play09:16

insecurity in you because that's a great

play09:18

motivator to buy things I'm not going to

play09:21

sell you anything I never have I never

play09:24

will so supplements I'm going to tell

play09:28

you are effective and can be helpful

play09:31

specifically

play09:32

chromium chromium colonate zinc I know

play09:36

magnesium is very efficient very helpful

play09:38

I prescribe that to my patients other

play09:40

things I I prescribe to my patients is

play09:42

going to be if necessary I'm going to

play09:43

look at their calcium levels calcium

play09:44

does help I prescribe antioxidants

play09:47

antioxidants are incredibly helpful with

play09:48

women with PCOS that's a big role that

play09:50

goes on in there like well brenon Dr

play09:54

McCarthy what doses great question this

play09:57

is the part that's going to be crazy I

play09:59

run the

play10:01

lab I'm not going to tell you to take

play10:03

something if I don't see you needing it

play10:05

and if I see you need it I'm going to

play10:06

prescribe it

play10:07

correctly I run the zinc panel on you I

play10:10

run the Magnesium panel on you I run all

play10:12

these Labs on you to find out where you

play10:14

are and then I make my decision then now

play10:17

say you're in a place where your doctor

play10:19

won't run the labs what doses do you use

play10:22

it's it's very personal I'm going to be

play10:24

very honest with you on here I'm not

play10:25

going to sit here and tell you what

play10:26

milligram doses would do with anything

play10:28

I'm doing that on purpose because it's

play10:30

important to adjust doses based on

play10:33

success this has been my understanding

play10:35

throughout life if you give a person

play10:37

magnesium I've had this happen at had a

play10:39

patient who had no constipation uh

play10:41

secondary to magnesium deficiency

play10:43

because she had estrogen dominance so

play10:45

when your estrogen is very high and we

play10:48

give you

play10:49

magnesium what's happening is that

play10:51

magnesium plays a role with estrogen

play10:53

detoxification Pathways magnesium is a

play10:56

plays a role in the liver and it plays a

play10:58

role in that whole process of breaking

play10:59

down estrogen so if you have estrogen

play11:00

dominance too much estrogen chances are

play11:02

you're going to have low magnesium so

play11:04

I'm going to prescribe magnesium I've

play11:06

seen patients go online see magnesium

play11:08

they're like well I'm just take

play11:08

magnesium they'll take 140 milligrams or

play11:10

something that will do nothing nothing

play11:14

that I've seen other people do 800

play11:15

milligrams to to you know 1,200

play11:18

milligrams which is pretty heroic dosing

play11:21

the thing is with these we need to sit

play11:23

down with you and understand where you

play11:24

are and then approach it so I want you

play11:27

to know these are nutrients I use and I

play11:28

want to know that I want you if you were

play11:31

to use these to have your Physicians sit

play11:33

down and help you target it because what

play11:35

if you take that magnesium at 180

play11:38

milligrams and you said magnesium

play11:40

doesn't work but it does work

play11:42

supplements I think are very helpful so

play11:46

fasting to get mtor engage or autophagy

play11:51

remove mtor rather and get get uh

play11:53

autophagy going yes big and supplements

play11:55

to help nurture that pathway I'm going

play11:58

to talk about something uh controversial

play12:01

and heretical because it wouldn't be an

play12:02

episode if I didn't um rapamycin

play12:05

rapamycin is a fascinating medication uh

play12:09

that has significant impact on PCOS on

play12:13

women

play12:16

rapamycin you have to be very careful

play12:17

with dosing rapamycin I'll be clear on

play12:19

that and rapamycin a too high of a dose

play12:21

is immune modulating immune suppressing

play12:24

too low of a dose doesn't really work

play12:26

you need to find the right dosy on it

play12:28

and the method of dosing it a lot of

play12:30

times in our practice we'll only do it

play12:31

once a week you take your rapid mein

play12:33

once a week we prescribe it it's

play12:35

prescrib medication and it's the benefit

play12:38

of it the impact it has on the insulin

play12:40

receptor is significant and measurable

play12:43

with lab work so we'll write the rap

play12:46

ayin for the patient to see you're like

play12:48

brenon what is rapamycin has it do melon

play12:51

Target of rap ayin or mtor which I

play12:54

mentioned earlier which fasting engages

play12:57

mtor that receptor mil Target of Romy

play13:00

Romy specifically hits that it rapy

play13:03

pushes your body into

play13:04

autophagy it's like helping your fast

play13:07

get better traction it helps your body

play13:10

heal itself better that's what rap ayin

play13:12

does proven in the literature deeply

play13:16

proven this is an off Lael use of it

play13:18

though the FDA has approved rap ayin for

play13:21

you know uh to prevent at high dosing to

play13:24

prevent uh organ transplant rejection

play13:26

true and good still as a physician part

play13:28

of what we do every physician does is

play13:31

use medications off label we are

play13:32

supposed to do it does that mean the

play13:34

medication is not FDA approved no that

play13:37

does not mean that what it means is that

play13:39

it is FDA approved as a medication we

play13:41

are allowed to prescribe it you can use

play13:43

it if you can show the benefit to the

play13:45

patient so when we use an off Lael

play13:47

medication like Rapa mein how do we do

play13:49

it we sit down with the patient we say

play13:51

this is what I think will work these are

play13:53

the pros and cons of it this is the

play13:54

research behind it this is how I expect

play13:56

it to work this is how I'm going to

play13:58

verify it works this is why it's safe

play14:00

this is where it would not be safe this

play14:02

is how I'm going to make it stay safe

play14:03

for you that's how use off label

play14:06

medication that's important anybody who

play14:09

says that off label medication is you

play14:11

know illegal or dangerous isn't really

play14:13

paying attention that's not medically

play14:15

true or sound so rap ayas in this case

play14:18

is an important component in my opinion

play14:21

for addressing the core cause of PCOS

play14:25

fasting and Rapid myosin hands down

play14:30

supplements after that what else do I

play14:34

do the diet that you do and many of you

play14:37

done you know a lot of you do low carb

play14:39

you know I get it you know I've done

play14:41

that too and ketosis diets and you'll do

play14:43

carnivore diets and you all these diets

play14:45

that are very very low carb and that's

play14:49

effective to a point it doesn't always

play14:50

work as I mentioned earlier is when

play14:53

you're doing some of these extreme

play14:54

diets any any any really far um control

play14:59

diets that are very extreme in the sense

play15:00

of you're only doing you're eliminating

play15:02

one whole food grp food group or you're

play15:04

only eating one specific type of food

play15:06

these are extreme by Nature you know

play15:08

that's how I feel about medicine excuse

play15:10

me feel about diet so when you do those

play15:12

types of diets you can have success but

play15:14

the success will be limited in my

play15:15

experience and don't does not last

play15:17

forever in these cases because the

play15:19

stress of it and the difficulty of

play15:21

having proper nutrition on these diets

play15:22

is is is a problem and nutrition is a

play15:24

big part of treating this you need to

play15:26

have the correct micronutrients around

play15:29

to benefit the person in front of you so

play15:32

I I want you to know when I do a diet

play15:35

for these women I don't I try and avoid

play15:38

doing diets that are difficult or

play15:39

stressful or um Limited in

play15:43

micronutrition my favorite diet to do

play15:46

and I mean this wholeheartedly and I

play15:48

give this my whole full throated support

play15:50

is a Whole 30 diet I have done that diet

play15:52

I prescribe that diet I live by that

play15:54

diet that is the key diet for my

play15:56

patients it works a close second to that

play15:59

it's going to be the Mediterranean diet

play16:01

but the Mediterranean diet is so like

play16:03

abstract people like well I can have

play16:04

spaghetti and meatballs that's a

play16:05

Mediterranean dish it is a Mediterranean

play16:08

dish you know that is true and a good

play16:10

set of good a good uh spaghetti

play16:12

meatballs is pretty dang delicious it's

play16:13

true true but that will not help you

play16:16

that's not technically that's not that's

play16:18

not the Mediterranean I'm trying to talk

play16:21

about so Mediterranean is tricky with

play16:22

patients you have to spend time with

play16:24

them doing education so with this diet

play16:26

we do a whole 30 diet and when we have

play16:29

this diet with patients I want to be

play16:30

very clear with you telling someone to

play16:32

go home and do Whole 30 diet can be

play16:34

tricky and it's not easy and a lot of

play16:35

times they feel alone and you get

play16:37

lost we sit down with our nutritionists

play16:40

you know my my partner in the practice

play16:42

my wife she's the my my partner in the

play16:44

practice uh she does nutrition at the

play16:47

office and and you know we really work

play16:49

hard to make sure it's accessible and

play16:51

understandable and we stand beside you

play16:53

and help you get through these diets so

play16:54

it's important to consider do you need

play16:56

someone who's been doing this for a

play16:57

while that doesn't mean you going to go

play16:58

to your doctor's office is it could be

play17:00

you talk to someone who's been doing

play17:02

these diets for a while maybe or maybe

play17:04

reaching out to the Whole 30 website and

play17:06

asking them for some guidance I know

play17:08

them they're very helpful people I've

play17:10

I've interacted with them on several

play17:12

occasions in my career I think very

play17:13

highly of them so that's that's a good

play17:15

option you know and with fasting another

play17:17

great resource Dr Jason fun I just love

play17:21

his work but also I like the kind of

play17:22

person he is his website has so many

play17:25

helpful tools there so when you do these

play17:27

things you don't have to onboard a real

play17:29

expensive nutritionist if you can't

play17:31

afford that or if it doesn't seem to

play17:32

work for you there's these resources you

play17:34

can do online with these people and I

play17:36

know these two companies are very very

play17:38

ethical people and my my personal

play17:40

experience with them as a physician so I

play17:41

do recommend them so when we have you do

play17:44

a whole 30 diet say I prescribe that for

play17:46

you I'll sit down with you and we'll

play17:48

create or the nutritious will sit down

play17:49

with you and create a diet plan you'll

play17:51

be like okay let's make a menu for the

play17:52

week and you create a menu of all the

play17:54

things you want to eat and then we

play17:55

create a shopping list with you and then

play17:58

you go fill the the shopping list and

play17:59

you prepare the food and we make a

play18:02

shopping list and a menu that you can do

play18:04

okay a menu if you're like I'm going to

play18:05

do this complex dish you got home from

play18:07

work at 6 o00 you don't have time to

play18:08

make a complex dish you you want to

play18:10

throw yourself in a crock pot or you

play18:11

want to throw yourself in an instant pot

play18:13

have it done so we make those diets work

play18:15

for you so a Whole 30 diet is a key part

play18:18

of this for me I've had tremendous

play18:20

success with it why is it good it

play18:22

emphasizes micronutrition through uh

play18:25

plant-based calories so so you know

play18:27

we're not doing grains on it okay so

play18:29

your carbs from there are reduced but

play18:31

you're going to be getting a lot of

play18:32

vegetables and fruit in there and the

play18:33

vegetables and fruit in there are going

play18:34

to give you the micronutrition that's

play18:36

going to have the zinc that's going to

play18:37

have Cobalt which I didn't mention

play18:39

minute ago that's another micronutrient

play18:40

that's helpful it's going to have in

play18:41

there the chromium all those

play18:43

micronutrients in the foods around you

play18:45

are more bioavailable and work better in

play18:47

a food substrate so we make sure you do

play18:49

that healthy diet this is how I approach

play18:53

my patients with PCOS to make sure I go

play18:55

after the core part of this that is

play18:57

getting to them now if you think about

play18:59

it what's different with what I just

play19:01

described with what people are

play19:02

prescribed in their standard appointment

play19:04

with their their physician the doctor

play19:06

will say just cut your

play19:07

calories they may say do keto maybe

play19:10

rarely but they'll say something like

play19:12

that they'll just say go on Weight

play19:14

Watchers and there's nothing wrong with

play19:15

Weight Watchers there's nothing wrong

play19:16

with keto these are good protocols for

play19:17

people because they make changes but

play19:19

this is a diagnosis with pathology and

play19:22

PCOS does not always respond to

play19:25

keto it doesn't always respond to Weight

play19:27

Watchers that's not not a dig on ketosis

play19:30

diets it's not a dig on way Watchers

play19:32

that's just the fact that the the

play19:34

insulin receptor is damaged and we need

play19:37

to Target it and repair it so I believe

play19:40

using micronutrition using uh timed

play19:43

eating that's very careful how you time

play19:45

it I believe that using a diet that is

play19:48

rich in micronutrition and low in the

play19:50

insulin index of foods that's what pie

play19:53

that's what the uh whole threeory diet

play19:55

is these are foods that don't stimulate

play19:57

a lot of insulin foods can stimulate

play20:00

insulin and foods can s stimulate

play20:01

glucose by the way there's the glucose

play20:04

uh uh index of foods and there's the

play20:05

insulin index of foods you know this you

play20:07

need to watch the insulin index because

play20:09

that's another thing that that will be

play20:10

triggering people with PCOS so we want

play20:13

to make sure you're doing a diet that's

play20:14

down that road of insulin index of foods

play20:16

and doing something like that that whole

play20:17

30 diet that's how we get through that

play20:20

two more things to add in here that are

play20:21

important that I bring up these are

play20:23

herbs berberine is a a tremendous asset

play20:28

to you

play20:29

in PCOS it's a tremendous asset and I'm

play20:32

going to do dose and I'm going to do

play20:34

brand right now because I herbs herbs

play20:36

are tricky because if you don't get it

play20:38

from a good source um you run the risk

play20:41

of number one getting nothing that works

play20:43

in there because it'll say oh this has

play20:44

berberine in here but really how many

play20:46

act how much active component of the the

play20:48

plant is in there so Gaia g a i a Gaia

play20:52

Herbs they don't know me from a bar soap

play20:55

they don't know me at all I love Gaia

play20:58

Herbs I've known them and love them

play20:59

since I first started doing this it's

play21:03

one of the more uh effective and and

play21:05

ethical and high quality companies out

play21:07

there and you find in almost every

play21:08

single health food store and I still

play21:10

stand by them they will you can buy your

play21:11

berberine from them and you look on the

play21:13

label and it'll even say how much active

play21:16

compounds are in there they measure it

play21:17

with thin layer

play21:18

chromatography they really do care about

play21:20

their product so I would use Gia

play21:23

berberine Plus or one of their other

play21:24

berberine compounds I would not do the

play21:26

liquid I would do the gel caps cuz

play21:28

liquid Bine tastes terrible terrible

play21:31

compliance drops off with liquid bourine

play21:33

so you want to do is a gel cap to get

play21:35

the best absorption rate in there that's

play21:36

been my experience with it another herb

play21:39

that I'm going to bring up is

play21:41

metformin you heard me right I called

play21:43

metformin an herb meformin originated as

play21:47

an herb that's where it started as and

play21:49

and it was repurposed as a

play21:51

pharmaceutical they pulled the active

play21:52

ingredient out of there and that's how

play21:54

they made metformin meformin is largely

play21:56

based upon an herb that's it for French

play21:58

lilac that's it so when you use

play22:02

metformin that's a plant-based

play22:03

medication even though it's been you

play22:05

know uh um turned into a pharmaceutical

play22:08

I have no problems with meformin I don't

play22:10

think it's a bad thing I think it's bad

play22:12

to park you on it and not try and fix

play22:14

you with all the other things with the

play22:16

timed eating with targeting the the

play22:18

theuh insulin receptor and trying to

play22:20

repair that I think just parking on in

play22:22

on meformin is not truly a good job so I

play22:26

put you on meformin along with this

play22:27

other protocol

play22:29

and and I watch how you progress I see

play22:31

how you

play22:32

go so this was my dietary approach to

play22:37

treating PCOS and I hope this

play22:40

helps it's by no means exhaustive but it

play22:43

gives you an idea how I look at it and

play22:45

how I unravel

play22:46

it your comments mean so much to me

play22:49

because it helps me do a good job at

play22:51

this because I do want to do a good job

play22:54

I'm not here to to to sound smart not

play22:58

here here

play22:59

to to sell you anything I just love

play23:03

doing this I love my work I really do

play23:06

it's a very rewarding thing that I do

play23:07

and it gives me fulfillment at a deep

play23:10

level and to be able to share that is

play23:12

priceless to me that's more important to

play23:14

me than anything else is being able to

play23:15

share that knowledge only has value if

play23:17

you share

play23:18

it has no other value in

play23:21

life so please like share and subscribe

play23:24

and I'll see you at the next episode The

play23:26

Next Episode we're going to go a little

play23:27

bit more into how to treat PCOS I'm

play23:29

going to get more specific on a couple

play23:30

of therapies that we employ in here I

play23:32

want to talk more about progesterone

play23:33

which is my favorite so the next episode

play23:35

we're going to talk about progesterone

play23:37

thank you again for tuning in I'll see

play23:38

you again the next time

play23:44

[Music]

Rate This

5.0 / 5 (0 votes)

Etiquetas Relacionadas
PCOS TreatmentInsulin ResistanceDiet TherapySupplementsIntermittent FastingAutophagyNutritionHealth PodcastMedical AdviceWhole 30 Diet
¿Necesitas un resumen en inglés?