The Science

Summary

In this discussion, an expert shares his enthusiasm for a weight loss product derived from hops extract, called 'Adify.' The product, which can be mixed with any liquid without altering taste, has been shown to stimulate the vagus nerve, leading to increased thermogenesis and weight loss by burning white fat. A clinical study demonstrated significant weight loss with usage limited to three days a week. The expert also touches on potential additional benefits such as anti-inflammatory properties and improved cognition, though these are still in early research stages. The product's development process has made it more concentrated and cost-effective than previous methods, offering a promising solution for health and weight management.

Takeaways

• 🔬 The speaker is excited about a project involving a weight loss product, emphasizing the importance of addressing obesity and metabolic syndrome, which are significant health concerns globally.
• 🌱 The product, 'Adify', is derived from hops extract, a byproduct of the brewing process, and is considered a safe and effective solution for weight loss after conducting their own study.
• 📊 The study mentioned involved using the product three days a week and showed a statistically significant weight loss compared to a placebo group, with a P value of 0.01.
• 🍺 The product is tasteless and odorless, making it easy to incorporate into any liquid, and is affordable, potentially making it accessible to a wide audience.
• 🔑 Adify works by stimulating a receptor in the intestinal tract, activating the vagus nerve, which in turn stimulates brown fat, leading to increased thermogenesis and calorie burning.
• 🏋️‍♂️ Brown fat is known to be more prevalent in athletes and children, and less so as people age, which is part of the reason weight loss becomes more challenging with age.
• 🧊 The product's effectiveness was tested in heavy drinkers, a group typically difficult to help lose weight, and still resulted in weight loss, suggesting its potential for broader use.
• 🍾 The product contains a stabilizing agent, sodium metabisulfite, to keep it fresh and prevent spoilage, which is a common ingredient in wine.
• 💡 Other potential benefits of mature hops extract, such as anti-inflammatory properties and cognitive enhancement, are mentioned, though these are based on early research and not claims of the product.
• 📚 The process developed by the team to extract Adify is more efficient and cost-effective than previous methods, resulting in a higher concentration of the beneficial compound.
• 🚀 The speaker shares a personal anecdote of successfully losing weight while on a cruise using the product, highlighting its practical application and effectiveness.

Q & A

What was the initial conversation between Trey and the speaker about the weight loss project?

The initial conversation was casual, where Trey approached the speaker about a weight loss project, unsure if it worked as well as he thought it did, and asked if the speaker might be interested in working on it.

Why is the field of weight loss considered important today?

The field of weight loss is important because the American Heart Association has identified preventing metabolic syndrome and obesity as a priority, even more so than quitting smoking, due to their impact on heart disease.

What was the unique aspect of the study conducted by the speaker and his team?

The unique aspect of the study was that the product was only used three days a week, specifically on weekends, and the participants in the placebo group did not lose weight, while the active group lost an average of two and a half pounds.

What does a P value of less than 0.05 signify in a study?

A P value of less than 0.05 is considered statistically significant, indicating that the results of the study are unlikely to have occurred by chance.

What is Adify and how is it related to the hops plant?

Adify is a made-up term for a material hops extract derived from the hops plant, which is commonly used in the brewing process for beer. The extract, which was previously considered a waste product, is now being utilized for its weight loss properties.

How does Adify work to stimulate thermogenesis without causing shivering?

Adify works by stimulating a receptor in the intestinal tract, which activates the vagus nerve. This nerve then sends an impulse to brown fat, causing it to increase thermogenesis and burn calories without the need for shivering.

What is the role of sodium metabisulfite in the Adify product?

Sodium metabisulfite is used as a stabilizer to keep the natural product fresh and prevent it from breaking down, ensuring its effectiveness over time.

How does the activation of brown fat through Adify compare to other methods like ice baths or exercise?

Activating brown fat through Adify allows for thermogenesis and weight loss without the discomfort of ice baths or the rigorous commitment to exercise, offering a more accessible and convenient method.

What was the significance of the study conducted with heavy drinkers and how did it relate to the effectiveness of Adify?

The study with heavy drinkers was significant because it demonstrated that Adify could help this group lose weight, suggesting that the product could be even more effective for individuals who are not typically heavy drinkers.

What are some of the potential additional benefits of Adify beyond weight loss mentioned in the script?

Beyond weight loss, potential additional benefits of Adify include anti-inflammatory properties, improved cognition, and possibly reduced risk of dementia, although these are still early research findings and not confirmed health claims.

What was the speaker's personal experience with Adify and how did it impact his weight?

The speaker's personal experience with Adify involved losing weight during a week-long cruise, where he was able to shed three pounds despite the abundance of food, and eventually lost a total of 20 pounds while using the product.

How does the concentration level of Adify compare to previous studies and products?

The concentration level of Adify is over twice as high as what was used in previous studies, and it is produced in a more cost-effective manner, making it more accessible for commercial use.