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23 May 201805:48

Summary

TLDRThis video explores two prominent theories about how enzymes work: the Lock and Key Theory and the Induced Fit Theory. The Lock and Key Theory, proposed by Emil Fischer, suggests that enzymes have a specific active site that binds only to a substrate with a complementary shape, much like a key fitting into a lock. In contrast, Daniel Koshland's Induced Fit Theory argues that enzymes have a flexible active site that adjusts its shape to bind with various substrates. The video delves into the distinct perspectives of these two theories, explaining the fundamental mechanisms behind enzyme function.

Takeaways

  • 😀 The video discusses two theories explaining how enzymes work: the lock and key theory and the induced fit theory.
  • 😀 Emil Fischer proposed the lock and key theory, which suggests that enzymes have a specific active site designed to fit a particular substrate.
  • 😀 The lock and key theory describes the enzyme's active site as rigid, meaning it only binds to substrates with a matching shape.
  • 😀 The induced fit theory, proposed by Daniel Koshland, explains that the enzyme's active site is flexible and adjusts to fit the substrate.
  • 😀 According to the induced fit theory, the enzyme's active site changes shape when a substrate binds, enabling a more general interaction.
  • 😀 The lock and key theory is compared to a key fitting perfectly into a lock, with no flexibility in the enzyme's structure.
  • 😀 The induced fit theory allows for a broader range of substrates to bind with the enzyme, due to the flexibility of the active site.
  • 😀 The video emphasizes that both theories provide different perspectives on enzyme functionality but are both important for understanding enzyme action.
  • 😀 The lock and key theory is based on a specific, unchanging shape for both the enzyme and the substrate.
  • 😀 The induced fit theory highlights the adaptability of enzymes, allowing them to accommodate substrates with various shapes.

Q & A

  • What are the two theories explaining how enzymes work?

    -The two theories are the Lock and Key Theory and the Induced Fit Theory.

  • Who proposed the Lock and Key Theory?

    -The Lock and Key Theory was proposed by Emil Fischer.

  • What does the Lock and Key Theory suggest about enzyme-substrate interaction?

    -The Lock and Key Theory suggests that enzymes have a specific active site that fits only a particular substrate, like a key fitting into a lock.

  • What is the main idea behind the Induced Fit Theory?

    -The Induced Fit Theory suggests that the enzyme's active site is flexible and can adjust its shape to fit the substrate, even if the shapes don't initially match.

  • Who proposed the Induced Fit Theory?

    -The Induced Fit Theory was proposed by Daniel Koshland.

  • How does the enzyme's active site behave according to the Lock and Key Theory?

    -According to the Lock and Key Theory, the enzyme's active site is rigid and only binds to a specific substrate that has a complementary shape.

  • How does the enzyme's active site behave according to the Induced Fit Theory?

    -In the Induced Fit Theory, the enzyme's active site is flexible and can change shape to accommodate a substrate that does not initially match its shape.

  • What is the name of the complex formed when the enzyme binds with the substrate?

    -The complex formed is called the enzyme-substrate complex.

  • Which theory suggests that the enzyme's active site is specific and does not change shape?

    -The Lock and Key Theory suggests that the enzyme's active site is specific and does not change shape.

  • Which theory allows the enzyme to bind to any substrate as long as the active site is flexible?

    -The Induced Fit Theory allows the enzyme to bind to any substrate as long as the active site is flexible and can adjust its shape.

Outlines

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Transcripts

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الوسوم ذات الصلة
EnzymesLock and KeyInduced FitBiologyBiochemistryScientific TheoriesEnzyme ActionFischerKoshlandActive SiteSubstrate Binding
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