Filling of hard gelatin capsules part 2, dosator machine, dosing disc machine, vacuum filling

The Pharma Guide
23 Jul 202112:30

Summary

TLDRThis video covers the working principles of powder compression machines used to fill hard capsules. It explains the mechanics of these machines, including powder pressing, tablet formation, and filling capsules with compressed powder. The process involves stages such as adjusting piston height, controlling powder dosage, compressing powder into slugs, and inserting them into capsules. The script also touches on vacuum systems used to maintain precision in filling, ensuring capsule consistency. The video emphasizes the importance of accurate powder measurement and machine operation for a successful capsule-filling process.

Takeaways

  • 🧪 The video covers the working principle of gelatin capsules and how powder is compressed to form tablets.
  • ⚙️ The powder is compressed under low pressure to maintain its soft texture, which is essential for capsule formation.
  • 🔧 The process involves a machine with a piston that compresses the powder to form compact slugs, which are then transferred into capsules.
  • 📉 Lower pressure is used for compression compared to the pressure used in tablet formation, ensuring a gentle process.
  • 🌡️ The machine's piston system adjusts to specific heights to allow for precise powder filling and compression in each capsule.
  • 🔍 The video explains how excess powder is removed through a process called 'doctoring,' which ensures the proper amount remains in the capsule.
  • 🔄 Multiple stages are involved, including powder filling, compression, and inserting the compressed powder into capsules.
  • 📦 The machine can perform several cycles per minute, ensuring efficient capsule filling and compression.
  • 📏 The importance of maintaining a consistent powder level and compression pressure is highlighted for accurate dosing.
  • 💊 The video concludes with an overview of the capsule filling machine's stages and operations, explaining how powder transforms into capsules.

Q & A

  • What is the primary focus of the video discussed in the transcript?

    -The video focuses on the working principles of machines used in capsule filling processes, particularly the compression of powders into capsules using adjustable systems and specific pressures.

  • What are the two main types of machines mentioned for powder compression?

    -The two main types of machines mentioned are 'tablet presses' and 'slug machines,' both of which are used to compress powders into capsules or tablets under varying pressures.

  • How does the powder compression process take place according to the transcript?

    -The powder is filled into a cavity, compressed by pistons to form a tablet or slug, and then transferred into capsules. The pressure applied is controlled, and any excess powder is removed during the process.

  • What role does the adjustable system play in the capsule filling process?

    -The adjustable system controls the height of the piston and the amount of powder filled into the cavity, ensuring precise compression and proper capsule formation.

  • How is excess powder removed after compression?

    -Excess powder is removed using a 'doctor plate' or 'scraper' which ensures that only the correct amount of powder remains in the cavity before compression.

  • What does 'slug formation' refer to in the context of the video?

    -Slug formation refers to the process where powder is compressed into a solid mass (slug) before being transferred into capsules. This is a crucial step in ensuring proper capsule filling.

  • What is the significance of vacuum application in the powder filling process?

    -Vacuum is applied to hold the powder in place within the cavity before compression. It ensures that the powder remains in position and prevents any air pockets from forming during the process.

  • What does the term 'doctoring' refer to in the video?

    -Doctoring refers to the process of removing excess powder after it has been filled into the cavity but before compression, ensuring that the correct dosage is maintained.

  • What happens in the second stage of the powder compression process?

    -In the second stage, the powder is compacted further into a solid form within the cavity, creating a consistent tablet or slug that can be inserted into capsules.

  • How is uniformity in powder level maintained during the filling process?

    -A constant powder level is maintained through sensors that detect the amount of powder in the cavity. The system automatically adjusts to ensure consistent filling throughout the process.

Outlines

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Transcripts

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الوسوم ذات الصلة
Powder CompressionCapsule FillingMachinery ProcessPrinciple StudyDevice TypesIndustrial MachinesPharmaceutical IndustryTablet FormationVacuum SystemsCompression Techniques
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