The TRUTH about NAD+ (You Could Be Taking it the Wrong Way)

Summary

This video highlights the anti-aging potential of NAD supplements and reveals key factors that can impact their effectiveness. Dr. Anil Badgnath explains that different NAD sources, such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), offer varying benefits for cardiovascular, cognitive, and muscular health. He emphasizes the importance of proper dosing and the role of antioxidants like resveratrol and quercetin in enhancing NAD's effects, especially for older individuals. The video offers actionable tips to maximize NAD's anti-aging power and improve overall well-being.

Takeaways

• 🧬 NAD supplements may be ineffective if not taken properly, as recent research reveals three critical factors impacting their effectiveness.
• ⚖️ Different types of NAD supplements provide different benefits. Nicotinamide mononucleotide (NMN) is particularly strong for cardiovascular health and diabetes, while Nicotinamide Riboside (NR) supports brain and muscle health.
• 💪 NMN increases NAD levels quickly, leading to benefits like more energy, reduced inflammation, better memory, heart protection, and weight loss without exercise.
• 🧠 NR is effective in improving cognitive function, reducing the risk of Alzheimer's, and boosting memory. It also restores muscle function in age-related weakness.
• ⏳ B vitamins can increase NAD, but their effects take longer to manifest (4-10 months) compared to NMN and NR.
• 💊 Proper dosing is crucial. Studies suggest 500mg of NR and 1200mg of NMN per day for maximum anti-aging benefits while staying safe.
• ⏲️ NAD supplements may become less effective as people age due to oxidative stress, which reduces the activation of sirtuins, the proteins responsible for cell repair.
• 🍇 Antioxidants like resveratrol (found in berries and red wine) and quercetin (found in currants and onions) protect sirtuins from oxidative stress, enhancing NAD’s effectiveness.
• 💡 For maximum anti-aging benefits, NAD supplements should be combined with antioxidants such as resveratrol and quercetin.
• 📚 Regular updates on health topics can help in learning new strategies for staying youthful and healthy, as emphasized by Dr. Anil Badgnath.

Q & A

What is NAD and why is it important?

NAD is an important enzyme found in every cell of our body. It plays a critical role in energy production, cellular repair, and preventing age-related health decline, making it popular for anti-aging purposes.

What is the main issue with taking NAD supplements?

The main issue is that our bodies aren't used to processing raw NAD directly from supplements. Instead, they prefer to build NAD from certain nutrients like B vitamins, nicotinamide mononucleotide (NMN), and nicotinamide riboside (NR).

How do nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) differ in their benefits?

NMN is particularly strong in cardiovascular health, helping with heart protection, diabetes support, and weight loss. NR, on the other hand, is more effective for brain and muscle health, aiding in neurological recovery, memory, and preventing age-related muscle weakness.

What role do B vitamins play in increasing NAD levels?

B vitamins, like niacin, are effective in increasing NAD levels, offering anti-aging benefits such as improved strength, energy, and liver health. However, it can take 4 to 10 months to see these benefits.

How does dosage affect the effectiveness of NAD supplements?

Higher dosages generally lead to quicker improvements in cognitive, muscular, and cardiovascular health, while very low dosages may not produce noticeable anti-aging effects. Safe dosages for NR are up to 500mg per day, and for NMN, up to 1200mg per day.

Why is NAD less effective in older individuals?

As we age, oxidative stress reduces the effectiveness of sirtuins, proteins activated by NAD that play a key role in cellular repair. This makes NAD supplements less effective in older individuals unless oxidative stress is addressed.

What are sirtuins and how do they relate to NAD?

Sirtuins are proteins that, when activated by NAD, initiate cellular repair processes, helping reverse cognitive decline and organ damage. They are key to NAD's anti-aging properties.

How can the effectiveness of NAD supplements be preserved in older individuals?

Combining NAD supplements with antioxidants like resveratrol and quercetin can protect sirtuins from oxidative stress, ensuring that NAD supplements remain effective even in older individuals.

What are the benefits of resveratrol and quercetin?

Resveratrol helps protect cardiovascular, liver, and digestive health, while quercetin can lower blood pressure and reduce the risk of stroke. Both antioxidants help combat oxidative stress, preserving the effectiveness of NAD supplements.

What should you consider when choosing an NAD supplement?

When choosing an NAD supplement, consider the source of NAD (NMN or NR), the dosage, and whether you are addressing specific needs like cardiovascular health, cognitive function, or muscle strength. Additionally, combine it with antioxidants like resveratrol and quercetin for maximum effectiveness.

Outlines

00:00

🔍 The Importance of NAD and Factors Affecting Its Effectiveness

NAD is a critical enzyme that supports energy production and prevents age-related health decline. However, new research reveals that NAD supplements may be ineffective due to three key factors. These findings make it crucial to understand how to properly use NAD to maximize its anti-aging benefits. This section introduces the importance of NAD in cellular function and highlights the need to overcome these obstacles for effective supplementation.

05:00

💊 Different NAD Supplements Offer Unique Benefits

Not all NAD supplements are the same, and they offer different anti-aging benefits based on their ingredients. NAD itself is difficult for the body to process directly, so supplements usually contain precursors like Nicotinamide Mononucleotide (NMN), Nicotinamide Riboside (NR), or B vitamins. NMN is shown to boost NAD levels quickly and is particularly beneficial for heart health, diabetes, and even weight loss. NR, on the other hand, is better for cognitive and muscle health. The choice between these sources depends on whether you prioritize cardiovascular, cognitive, or muscular benefits.

⚖️ The Importance of NAD Supplement Dosage

The effectiveness of NAD supplements depends significantly on the dosage. Higher dosages are linked to faster improvements in cognitive, muscular, and cardiovascular health. However, taking too low a dosage may result in no benefits. While doses of up to 500 mg of NR and 1200 mg of NMN are considered safe, individuals should carefully follow recommended levels to experience anti-aging effects. It's crucial to strike a balance between safety and effectiveness when choosing the right dose.

🧬 Age-Related Decline in NAD Effectiveness and How to Combat It

As people age, NAD becomes less effective, primarily due to oxidative stress, which weakens the proteins (sirtuins) that NAD activates. Sirtuins play a key role in cellular repair and reversing cognitive and organ decline. To combat this, antioxidants like resveratrol and quercetin can be used to neutralize oxidative stress and support the function of sirtuins. These antioxidants not only protect NAD's effectiveness but also offer their own health benefits, such as cardiovascular protection and lower blood pressure.

📋 Final Recommendations for Maximizing NAD Supplement Benefits

For NAD supplements to be effective, it’s important to choose the right ingredients and dosage, and to pair them with antioxidants like resveratrol and quercetin. This combination can help preserve NAD’s anti-aging properties and protect against oxidative stress. Supplements that include these antioxidants or adding them to your diet can provide an easy way to enhance NAD’s benefits. The section ends with a reminder to like the video and subscribe for more health-related content.

Keywords

💡NAD

NAD (Nicotinamide Adenine Dinucleotide) is a critical enzyme found in every cell of the body, responsible for energy production and cellular health. In the video, NAD is highlighted for its anti-aging potential, helping prevent age-related decline. It activates sirtuins, proteins that assist in cell repair, making it essential for maintaining youthfulness.

💡Sirtuins

Sirtuins are proteins that are activated by NAD and play a key role in cell repair and longevity. The video explains that sirtuins help combat cognitive decline and organ damage, thus being pivotal in NAD's anti-aging effects. However, oxidative stress reduces their effectiveness as we age.

💡Oxidative Stress

Oxidative stress is the damage caused by free radicals in the body, which accelerates aging by reducing the effectiveness of sirtuins. The video emphasizes that oxidative stress is a major factor that weakens the power of NAD supplements in older individuals, but antioxidants can help mitigate this issue.

💡Resveratrol

Resveratrol is an antioxidant found in berries, peanuts, and red wine, known for its ability to neutralize oxidative stress. In the video, it is mentioned as a compound that protects sirtuins, enhancing the effectiveness of NAD and providing its own anti-aging benefits, particularly for cardiovascular and liver health.

💡Quercetin

Quercetin is another antioxidant, abundant in currants, blueberries, and onions. Like resveratrol, it combats oxidative stress, preserving the function of sirtuins. The video highlights quercetin’s unique anti-aging properties, such as reducing blood pressure and stroke risk, making it a valuable supplement alongside NAD.

💡Nicotinamide Mononucleotide (NMN)

NMN is a precursor to NAD and one of the most effective ways to increase NAD levels quickly. The video states that NMN has numerous anti-aging benefits, especially for cardiovascular health, insulin effectiveness, and metabolism. It's also linked to weight loss without exercise.

💡Nicotinamide Riboside (NR)

NR is another NAD precursor that is particularly effective in protecting the brain and muscles from age-related decline. The video suggests that NR is beneficial for neurological recovery, reducing Alzheimer’s disease risk, and maintaining muscle function, making it ideal for those focused on cognitive and muscular health.

💡Dosage

The dosage of NAD supplements is crucial for experiencing their anti-aging benefits. The video explains that higher dosages tend to lead to faster improvements in health, but warns against very low doses, which may provide no benefits. Recommended safe dosages for NR and NMN are given to ensure effectiveness.

💡Anti-aging

Anti-aging refers to the process of slowing down or reversing the effects of aging on the body. NAD supplements are highlighted as a way to fight aging by promoting cellular repair and preventing age-related health issues like cognitive decline, muscle weakness, and cardiovascular problems.

💡Cardiovascular Health

Cardiovascular health refers to the proper functioning of the heart and blood vessels. The video highlights that NAD, particularly in the form of NMN, offers protection against heart disease. NMN is associated with improvements in heart function, insulin effectiveness, and metabolism, making it beneficial for those focused on maintaining heart health.

Highlights

NAD is an important enzyme found in every cell of the body, essential for energy production and preventing age-related decline.

There are three factors that can greatly impact the effectiveness of NAD supplementation.

Different types of NAD supplements provide different benefits depending on their source ingredients, such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR).

NMN increases NAD levels rapidly and provides strong cardiovascular and metabolic benefits, including protection against heart disease and aiding weight loss without exercise.

NR is more effective for improving brain and muscle health, with benefits such as protecting against brain hemorrhages, enhancing learning and memory, and improving muscle function.

B vitamins, like niacin, can also increase NAD levels but take longer (four to ten months) to show benefits.

Higher doses of NAD supplements lead to quicker improvements in cognitive, muscular, and cardiovascular health, but low doses may provide no benefits at all.

For NR, dosages as high as 500 mg per day are considered safe, while for NMN, up to 1200 mg per day is safe.

As people age, NAD supplements become less effective due to oxidative stress, which affects the activation of proteins called sirtuins that drive the anti-aging effects.

Oxidative stress reduces the effectiveness of sirtuins, which NAD relies on for anti-aging properties.

Antioxidants like resveratrol and quercetin can help protect sirtuins from oxidative stress and enhance the anti-aging benefits of NAD supplements.

Resveratrol, found in berries, peanuts, and red wine, helps protect cardiovascular, liver, and digestive health.

Quercetin, found in blueberries, onions, and currants, lowers blood pressure and reduces the risk of stroke while protecting against oxidative stress.

Combining NAD supplements with antioxidants like resveratrol and quercetin is essential for maximizing anti-aging effects.

Dosage and combining NAD with antioxidants are critical for ensuring effectiveness and overcoming the weakening effect of aging on NAD supplementation.

Transcripts

could millions of us be missing the true

anti-aging power of nad

recent scientific findings have revealed

that one little known problem may render

these supplements entirely ineffective

in fact researchers have discovered

three factors that greatly impact the

effectiveness of nad supplementation

even though this unique enzyme is widely

known to keep us feeling younger these

issues can greatly undermine its power

when taken in a supplement that makes

understanding these findings essential

to taking nad the correct way so what's

the truth about nad well right now i'm

going to break down this surprising

research so we can better understand

exactly how we can use nad supplements

to fight aging i'll reveal three facts

you must know about how to get the most

out of nad

how one major problem can make these

supplements completely ineffective and

what you could do to overcome this

threat what is nad

nad is an important enzyme found in

every cell in our body we produce nad

naturally because it performs a variety

of key roles in our cells mitochondria

for this reason nad is critical for our

body's energy production keeping

ourselves from breaking down and

preventing age-related health decline

that's why nad is popular with those

looking to protect their youth but

despite its popularity and anti-aging

potential there are many critical facts

about nad that most people don't know

about these factors are extremely

important to getting the most out of an

nad supplement in fact one of them is a

massive problem with these supplements

that may make them completely

ineffective in regards to anti-aging so

let's get right into it the first thing

you need to know about nad is number one

different types of nad supplements have

different benefits if you've browsed nad

supplements before you may have noticed

that most of them don't actually list

nad as an ingredient the reason why is

that until recently many experts believe

that our bodies wouldn't know how to

process raw nad if taken orally that's

because our bodies aren't used to

getting nad directly from food instead

they're used to using nutrients that we

eat to build nad themselves these

nutrients include b vitamins

nicotinamide mononucleotide and

nicotinamide riboside that's why

supplements that try to raise your nad

levels usually contain one of these

three ingredients curiously while each

of these ingredients increase your nad

their specific anti-aging benefits

actually vary let's quickly compare what

these three nad sources can do for you

nicotinamide mononucleotide a wide array

of clinical trials indicate that

nicotinamide mononucleotide or nmn for

short increases nad levels very quickly

sometimes in a matter of days these

studies found that this led to a wide

array of anti-aging benefits including

better energy less inflammation and

improve learning and memory however the

research suggests that nmn is

particularly strong when it comes to

cardiovascular benefits clinical studies

shown that nmn offers protection against

heart disease it also has several

documented benefits for diabetes

including insulin effectiveness stronger

metabolism and lower blood sugar

amazingly one study even showed that nmn

increased natural energy production so

much it led to weight loss without

exercise so if you're looking to protect

your heart fight diabetes and lose

weight nicotinamide mononucleotide may

be the better nad source for you on the

other hand nicotinamide ribocide may

have the advantage in keeping your

muscles and brain feeling young like nmn

it's been shown to increase nad and

deliver benefits very quickly studies

indicate that nr helps protect against

brain hemorrhages and can speed up

neurological recovery it's also widely

documented to boost learning and memory

amazingly in one study it reduced major

risk factors for alzheimer's disease

it also helped restore muscle function

from age-related weakness with that said

if you're more concerned about your

brain and muscles than your heart nr may

be the better option clinical trials

show that b vitamins like niacin are

effective in increasing nad which offers

anti-aging benefits by itself however

it's hypothesized that other forms

mentioned above offer more benefits one

study finds that b vitamins led to

increased nad levels as well as

improvements in strength energy and

liver health however it took four to ten

months to see these benefits based on

the evidence nicotinamide riboside and

nicotinamide mononucleotide might be the

better nad sources but when picking

between these two sources consider

what's more important to you cognitive

and muscular health nr might be the

better pick cardiovascular health

diabetes support and weight loss

consider trying nmn instead now while

the nad source decides which particular

benefits you'll see

the next topic has to do with how

quickly those benefits will come

dosing matters along with all the

different sources of nad out there

supplements also provide a wide range of

dosages in general studies seem to link

higher dosages to quicker improvements

in cognitive muscular and cardiovascular

health on the other hand some trials

found that very low dosages led to no

anti-aging benefits at all

however it's still wise to practice

caution when taking nad supplements for

nr studies find that dosages as high as

500 milligrams per day are safe

meanwhile studies show that nmn dosages

up to 1200 milligrams per day are

considered safe to feel these

supplements anti-aging effects as fast

as possible while staying safe it's

likely best to stay close to these

dosages however even if you choose the

best possible nad source and dosage

there's still one more problem listen

closely because unless you address this

issue your nad supplement may become

completely useless nad is less effective

in older folks paradoxically the

anti-aging effects of nad get weaker the

older you are however there's a simple

strategy that can keep nad supplements

effective but before we discuss that we

need to get deeper into where nad gets

its anti-aging properties see nad

activates a special type of protein

called sirtuins when sirtuins are

activated it tells our cells to start

repairing themselves this is how our

bodies reverse cognitive decline and

organ damage so nad gets its anti-aging

power from sirtuins however an aging

process called oxidative stress makes

sirtuins lose effectiveness over time

that means the older you are the less

effective nad supplements become but

what if we could combat oxidative stress

that's where a powerful group of

nutrients called antioxidants come in

and two antioxidants in particular have

been shown to protect sirtuins and help

them keep you feeling young the first

antioxidant is called resveratrol

resveratrol is found in berries peanuts

and red wine this antioxidant is known

to target and neutralize chemicals that

cause oxidative stress in addition to

keeping nad and sirtuins effective

resveratrol has its own array of

anti-aging benefits studies have shown

that it can protect your cardiovascular

liver and digestive health the second

antioxidant is called quercetin

quercetin is found most abundantly in

currents blueberries and onions like

resveratrol quercetin helps stop

oxidative stress from wearing down on

sirtuins similarly still quercetin also

brings unique anti-aging benefits

including lower blood pressure and

decreased risk of stroke so if you're

taking a nad supplement make sure to

combine it with lots of resveratrol and

quercetin if you want a quick and

convenient way to get more of these

antioxidants without changing your diet

you can also get them in supplement form

just to recap

nad supplements are highly effective for

anti-aging but when looking for one keep

its ingredients and dosage in mind and

be sure to combine it with quercetin and

resveratrol please like this video and

subscribe to my youtube channel where

i'll be discussing new exciting health

topics regularly i'm dr anil badgnath

wishing you the best on your journey to

becoming a more youthful you