Topical Finasteride For Hair Loss: How to Use and Where To Get It

Summary

In Episode 34 of The Hair Loss Show, Dr. Vikram Jayaprakash and Dr. Russell Knudsen discuss the topical version of Finasteride, a treatment for hair loss. They compare it to the oral version, which has been in use since 1997 and has known side effects. Topical Finasteride is applied directly to the scalp to minimize systemic side effects, with typical concentrations of 0.1% to 0.25%. The podcast highlights the ongoing debate about its effectiveness and side effects, emphasizing the need for more scientific research beyond anecdotal evidence. The doctors also stress the importance of proper compounding for topical Finasteride.

Takeaways

• 👨‍⚕️ Dr. Vikram Jayaprakash and Dr. Russell Knudsen discuss hair loss treatments, focusing on Finasteride.
• 💊 Finasteride was released in the U.S. in 1997 for oral use to treat hair loss, with 23 years of experience.
• 🔎 Side effects of oral Finasteride have been discussed in previous podcasts, including episode number four.
• 🧪 Topical Finasteride has been developed to apply medication locally and potentially reduce side effects.
• 🧠 The original theory for oral Finasteride was to block 5 Alpha Reductase Enzymes in the liver to reduce DHT levels systemically.
• 🚦 Finasteride partially blocks the enzyme, lowering DHT by about two-thirds, not completely.
• 🧴 Topical Finasteride is typically dosed at 0.1% or 0.25% and is applied daily to thinning areas, not bald spots.
• ⚖️ There's ongoing debate about whether topical Finasteride completely eliminates side effects, as some patients still experience them.
• 🔄 Topical Finasteride must be compounded by a professional to ensure a stable and reproducible solution.
• 📉 Doctors generally prefer oral Finasteride but will consider topical alternatives for patients concerned about side effects.
• 🔬 Future research is needed for controlled studies on topical Finasteride to provide more scientific evidence.

Q & A

What is the primary topic discussed in The Hair Loss Show Episode 34?

The primary topic discussed in The Hair Loss Show Episode 34 is the use of topical Finasteride as a treatment for hair loss in both men and women.

Since when has oral Finasteride been used to treat hair loss in the U.S.?

Oral Finasteride has been used to treat hair loss in the U.S. since 1997.

What is the theory behind using oral Finasteride instead of topical treatments like Minoxidil?

The theory behind using oral Finasteride is that 5 Alpha Reductase Enzymes exist in the liver, and by taking it orally, it can block the enzyme in the liver, reducing the amount of DHT delivered to the scalp.

How does Finasteride work in the context of hair loss?

Finasteride works by inhibiting the 5 Alpha Reductase Enzyme, which converts Testosterone into Dihydrotestosterone (DHT). By lowering DHT levels, it helps prevent hair follicles from miniaturization and hair loss.

What is the proposed advantage of topical Finasteride over oral Finasteride?

The proposed advantage of topical Finasteride is that it is applied directly to the scalp, which may reduce the risk of systemic side effects by keeping the effect localized.

What are the typical concentrations of Finasteride used topically?

Typical concentrations of Finasteride used topically are around 0.1%, although in some cases, it can be as high as 0.25%.

Why is it important to compound topical Finasteride properly?

Topical Finasteride needs to be compounded properly to ensure a stable and reproducible solution that can be consistently used over time.

What is the current stance of the doctors on the podcast regarding the use of topical Finasteride?

The doctors on the podcast prefer patients to use oral Finasteride as the first choice, but they are willing to prescribe topical Finasteride for those who are concerned about or experiencing side effects from oral use.

Are there any reported side effects from using topical Finasteride?

Yes, there are reports of side effects from using topical Finasteride, even at low doses, indicating that some patients may still be susceptible to side effects.

What is the difference between a scientific study and an anecdotal study as mentioned in the podcast?

A scientific study is a controlled and systematic investigation that provides evidence-based results, whereas an anecdotal study is based on personal accounts or individual experiences, such as 'Joe tried it and it worked,' without rigorous scientific methodology.

What is the future outlook for research on topical Finasteride according to the podcast?

The podcast hosts express hope that more research, specifically controlled scientific studies, will be conducted in the coming years to provide more definitive information on the effectiveness and side effects of topical Finasteride.