Membuat Sediaan Tablet Cara Cetak Langsung - Farmasi

Summary

In this educational video, Lestari demonstrates the process of preparing a direct compression tablet formulation using Ibuprofen. The video outlines the necessary formula and materials, such as Ibuprofen (400 mg), magnesium stearate (2%), and avicel PH 102. It provides a detailed explanation of how to calculate the required amounts of each ingredient to create a batch of 650 grams, producing 20 tablets. Lestari guides viewers through each step, from mixing ingredients to compressing tablets, with the goal of helping learners understand the practical aspects of tablet production. The video concludes with encouragement for students in pharmaceutical education.

Takeaways

• 😀 The video introduces the process of making direct compression tablets, with a focus on Ibuprofen as the active ingredient.
• 😀 The formula used for the tablets includes Ibuprofen 400mg, starch, magnesium stearate, and avicel PH 102.
• 😀 A batch of 650 grams of the tablet mixture is used to create 20 tablets in this process.
• 😀 The ingredients and their proportions are carefully calculated based on the desired tablet weight of 650 mg per tablet.
• 😀 The required amount of each ingredient is: 8 grams of Ibuprofen, 0.65 grams of starch, 0.26 grams of magnesium stearate, and 0.65 grams of avicel PH 102.
• 😀 The total weight of all ingredients is 13 grams, and the remaining weight (3.44 grams) is attributed to the excipients used in the tablet formulation.
• 😀 The preparation process starts with measuring and mixing the ingredients, including grinding them into a fine and homogeneous mixture in a mortar.
• 😀 After the ingredients are well-blended, magnesium stearate is added as a lubricant, and the mixture is further processed.
• 😀 The final mixture is then transferred into a tablet press machine for the compression process, forming the tablets.
• 😀 The video concludes with the hope that viewers find the tablet-making tutorial useful and that it helps in learning how to prepare tablets using direct compression.

Q & A

What is the main purpose of the video?

The main purpose of the video is to demonstrate the process of making direct compression tablets, focusing on the necessary steps and materials involved.

Who is the speaker in the video?

The speaker is Lestari, who introduces the process and formula for tablet preparation.

What active ingredient is used in the tablet formula?

The active ingredient used in the tablet formula is Ibuprofen, with a dosage of 400 mg per tablet.

What other materials are included in the tablet formulation besides Ibuprofen?

Besides Ibuprofen, the formulation includes amylase (as a diluent), magnesium stearate (as a lubricant), and Avicel PH 102 (as an absorbent).

What is the total weight of the formula for making 20 tablets?

The total weight of the formula for making 20 tablets is 650 grams.

How is the required amount of each ingredient calculated?

The required amount of each ingredient is calculated based on the weight of one tablet, with percentages of ingredients such as amylase, magnesium stearate, and Avicel PH 102 given relative to the total weight.

What is the role of magnesium stearate in the tablet formulation?

Magnesium stearate acts as a lubricant in the tablet formulation, helping with smooth tablet compression and preventing sticking during the manufacturing process.

How should the ingredients be mixed according to the process?

The ingredients should be mixed in a mortar until they are fine and homogeneous. Magnesium stearate is then added and ground further to ensure uniformity before the mixture is transferred to a tablet press.

What machine is used for the tablet compression process?

A tablet press machine is used to compress the mixed ingredients into tablets.

What does the speaker hope the viewers will gain from the video?

The speaker hopes that the viewers will gain a clear understanding of the tablet manufacturing process, including the necessary techniques and materials, and find the video informative and useful.