Spencer Wells Building a family tree for all humanity

Tim Nimmo
2 May 201222:20

Summary

TLDRThis script details a speaker's journey through 17 countries, exploring human diversity and origins. It delves into genetics, particularly population genetics, to understand how humanity's diversity emerged and the timeframe of our evolution. The narrative highlights the African origin of all humans, traced through DNA, and the recent exodus from Africa around 60,000 years ago. It also discusses the Genographic Project, an initiative that invites public participation in genetic research to map human migration and preserve cultural heritage.

Takeaways

  • 🌏 The speaker has visited 17 countries and observed the incredible diversity of languages and cultures, highlighting the human species' variety in terms of language, appearance, and lifestyle.
  • πŸ” The talk focuses on using genetics and population genetics to understand the origin and development of human diversity across the globe.
  • 🧬 Charles Darwin's theory suggested that human ancestors likely originated in Africa, which is supported by the fossil record and the genetic similarity with our closest ape relatives.
  • 🏺 The study of human ancestry has traditionally relied on paleoanthropology and morphology, but this approach has limitations in providing definitive genealogical probabilities.
  • 🌲 Linnaeus' classification of human 'races' was based on skull shapes and other physical features, but such classifications have been largely dismissed due to their lack of scientific basis and racial bias.
  • πŸ”‘ DNA provides a more accurate way to trace human ancestry and construct a family tree. Genetic markers can indicate shared ancestry and help trace lineage back to common ancestors.
  • 🌳 Mitochondrial DNA (mtDNA) and the Y chromosome are used to trace maternal and paternal lineages, respectively, showing that all humans can be traced back to a common African ancestor.
  • πŸ•°οΈ The 'Out of Africa' theory is supported by genetic evidence, suggesting that modern humans migrated out of Africa around 60,000 to 70,000 years ago, a relatively recent event in evolutionary terms.
  • 🌑️ Around 70,000 years ago, the climate was harsh, with Africa drying out and the human population nearly going extinct. This period of environmental stress coincided with significant cultural and cognitive advances in humans.
  • 🎨 The development of modern language, art, and more sophisticated tool-making around 50,000 years ago is believed to have facilitated human survival and expansion out of Africa.
  • 🌐 The Genographic Project, launched in 2005, aims to collect and analyze hundreds of thousands of DNA samples to map human migration patterns and understand our shared ancestry, with a focus on indigenous populations and public participation.

Q & A

  • How many countries has the speaker visited in the last six weeks?

    -The speaker has visited 17 countries in the last six weeks.

  • What is the main focus of the project the speaker is involved in?

    -The main focus of the project is to understand human diversity using the tools of genetics, particularly population genetics.

  • What is the significance of the diversity in human languages as mentioned in the script?

    -The diversity in human languages, with around 6,000 different languages spoken by 6.5 billion people, illustrates the vast cultural and genetic diversity across the globe.

  • What does the speaker suggest is the 'surface thing' that one takes away from traveling the world?

    -The 'surface thing' that one takes away from traveling the world is the recognition of how different we are, rather than the idea that we are all one.

  • According to Darwin, what was the likely origin of mankind based on the distribution of living mammals and their extinct relatives?

    -Darwin suggested that Africa was likely the origin of mankind because each great region of the world has living mammals closely related to the extinct species of the same region, and Africa was the origin of apes, our closest relatives.

  • What is the difference between studying human ancestry through paleoanthropology and using genetic markers?

    -Paleoanthropology studies human ancestry by digging up fossils and analyzing morphology, while genetic markers use DNA to trace ancestry and provide a more precise understanding of genealogical relationships.

  • What is the significance of mitochondrial DNA (mtDNA) and the Y chromosome in genetic studies of human ancestry?

    -Mitochondrial DNA traces a purely maternal line of descent, while the Y chromosome traces a purely paternal line of descent, allowing scientists to construct detailed family trees for all of humanity.

  • What does the speaker suggest about the timing of when all humans shared a common ancestor, based on genetic evidence?

    -According to the genetic evidence, all humans shared a common ancestor, mitochondrial Eve, within the last 200,000 years, and the Y chromosome Adam lived around 60,000 years ago.

  • What environmental changes approximately 60,000 years ago may have influenced human migration out of Africa?

    -Around 60,000 years ago, the world was going into the worst part of the last ice age, causing significant climate changes including drying out of Africa, which may have influenced human migration.

  • What is the Genographic Project, and how can the public participate in it?

    -The Genographic Project is a global initiative that aims to map human migration patterns using DNA samples. The public can participate by ordering a DNA testing kit from the project's website, submitting their results to the database, and contributing to the scientific effort.

  • What is the purpose of the Legacy Fund associated with the Genographic Project?

    -The Legacy Fund is a charitable entity that receives a portion of the funds raised by the Genographic Project. It provides grants to indigenous groups around the world for educational and cultural projects that they initiate.

Outlines

00:00

🌏 Global Diversity and Human Origins

The speaker reflects on their travels to 17 countries and the profound diversity they've witnessed among people and languages. They discuss the use of genetics, specifically population genetics, to understand the origins and development of human diversity. The speaker emphasizes the distinction between our common ancestry with apes, which originated in Africa around 23 million years ago, and our human ancestry. They highlight the importance of studying human evolution beyond morphology, using DNA as a historical document to trace our genealogy and understand the timing and process of human diversification.

05:00

πŸ”¬ The Genetic Approach to Human Ancestry

This paragraph delves into the limitations of traditional paleoanthropology and the transition to genetic analysis for understanding human ancestry. The speaker critiques Linnaeus' racial categorizations and the lack of concrete data supporting the concept of distinct human races. They advocate for a genealogical approach using DNA as a historical record, explaining the basics of DNA structure and the significance of genetic mutations as markers of descent. The speaker outlines how these markers can be used to construct a comprehensive family tree for all of humanity, tracing back to our earliest ancestors.

10:01

🌳 The African Origin and Maternal Lineages

The speaker explains the genetic evidence supporting the African origin of all humans, with the deepest lineages found within Africa indicating a longer period of mutational diversity accumulation. They introduce 'Mitochondrial Eve', an African woman who lived around 200,000 years ago and from whom all current mitochondrial DNA diversity descends. The Y chromosome evidence also points to a single African male ancestor, suggesting a recent exodus from Africa within the last 60,000 years. The speaker ponders why humans remained in Africa until this point and didn't diversify earlier like other species, such as Homo erectus.

15:02

🏞️ Climate, Cultural Shifts, and Global Expansion

Discussing the environmental context of human migration, the speaker describes the harsh conditions of the last ice age and its impact on Africa, causing a significant reduction in habitable areas and a near-extinction event for humans. Around 60,000 years ago, a cultural and behavioral shift is hypothesized to have occurred, marked by the emergence of art, advanced tool-making, and possibly the development of complex language. These changes are believed to have facilitated human survival and expansion out of Africa, with early migrations along coastal routes and into new territories, leading to the global distribution of human populations.

20:02

πŸ“š The Genographic Project and Public Participation

The speaker introduces the Genographic Project, launched in 2005 with the aim of expanding the study of human origins using DNA analysis on a global scale. The project encompasses field research with indigenous populations, public participation through DNA testing kits, and the establishment of a Legacy Fund to support cultural and educational initiatives. The speaker shares the success of the project, with thousands of samples collected and significant public engagement, highlighting the project's contribution to our understanding of human migration and diversity.

Mindmap

Keywords

πŸ’‘Diversity

Diversity in the context of the video refers to the wide range of differences among people globally, including languages, cultures, appearances, and genetic makeup. The speaker emphasizes the vast diversity of human species, highlighting the existence of thousands of languages spoken by billions of people of different colors, shapes, and sizes. This concept is central to the video's theme, as it sets the stage for discussing how genetic studies can help explain the origins and spread of this diversity.

πŸ’‘Genetics

Genetics is the study of genes, heredity, and variation in living organisms. In the video, the speaker discusses how population genetics, a subfield of genetics, is used to understand human diversity and trace the lineage of modern humans. Genetics plays a crucial role in the narrative by providing the scientific tools to explore questions of human origins and migrations.

πŸ’‘Paleoanthropology

Paleoanthropology is the study of human evolution through the examination of fossils and ancient human remains. The video mentions this field as a historical approach to understanding human ancestry, where scientists would infer relationships and lineages based on the morphology of fossils. However, the speaker points out the limitations of this method, suggesting that genetics offers a more precise way to trace human ancestry.

πŸ’‘Mitochondrial DNA (mtDNA)

Mitochondrial DNA is the genetic material found in the mitochondria of cells, which is inherited solely from the mother. In the video, mtDNA is highlighted as a tool for tracing maternal lineages, providing insights into the ancestry of all living humans. The concept of 'Mitochondrial Eve,' an African woman from whom all modern humans inherited their mtDNA, is a key point in the script that illustrates the African origin of humanity.

πŸ’‘Y Chromosome

The Y chromosome is a sex-determining chromosome found in males and passed from father to son. The video uses the Y chromosome to trace paternal lineages and discusses the concept of 'Y-Chromosome Adam,' an African man from whom all modern humans inherited their Y chromosomes. This concept supports the idea that all humans share a recent common ancestor in Africa.

πŸ’‘Mutation

A mutation is a change in the DNA sequence. In the context of the video, mutations are significant because they create genetic markers that can be used to trace ancestry and construct family trees. The speaker explains that these mutations, which occur as DNA is passed down through generations, help scientists understand the genealogical relationships among individuals and populations.

πŸ’‘Genographic Project

The Genographic Project is an initiative aimed at understanding human migration patterns and history through DNA analysis. The video describes this project as a way to involve both indigenous populations and the general public in the study of human origins. The project's goal is to collect and analyze DNA samples from around the world to fill in the gaps in our understanding of human migration and diversity.

πŸ’‘Indigenous Peoples

Indigenous peoples are the original inhabitants of a particular region, who often have a strong connection to their ancestral lands. In the video, the speaker mentions the importance of studying indigenous populations for their genetic continuity and their potential to provide insights into the genetic history of humanity. The Genographic Project specifically includes field research with indigenous peoples to contextualize DNA results.

πŸ’‘Paleoclimatology

Paleoclimatology is the study of past climates and their effects on the Earth's environment. The video references paleoclimatology to explain the environmental conditions around 60,000 years ago, which influenced human migration out of Africa. The speaker describes how the drying of Africa and the onset of the ice age may have prompted a subgroup of Africans to leave and populate the rest of the world.

πŸ’‘Cultural Stasis

Cultural stasis refers to a period in which there is little or no change in a society's cultural practices or technology. The video script mentions a long period of cultural stasis in human history, from about a million years ago until around 60,000 to 70,000 years ago. The speaker suggests that a significant change in human behavior and technology occurred around this time, which may have facilitated the human migration out of Africa.

πŸ’‘Legacy Fund

The Legacy Fund is a charitable entity associated with the Genographic Project. It is mentioned in the video as a means of giving back to indigenous communities by providing grants for cultural and educational projects. The fund represents the project's commitment to supporting the preservation of cultural heritage and diversity, which is central to its mission.

Highlights

The speaker has visited 17 countries and experienced a wide range of cultures, emphasizing the diversity of human languages and appearances.

The use of genetics and population genetics to understand human diversity and its origins is discussed.

Darwin's theory suggests that Africa is the most probable origin for human ancestors due to the fossil evidence and the continent's isolation.

The limitations of paleoanthropology and the need for a genealogical approach to understand human ancestry are highlighted.

DNA as a historical document that traces our ancestry and the concept of genetic markers of descent are introduced.

Mitochondrial DNA and Y chromosome are used to trace maternal and paternal lineages, respectively.

African populations have the deepest lineages and the greatest genetic diversity, supporting the Out of Africa theory.

The concept of 'Mitochondrial Eve' and 'Y Chromosome Adam' as recent common ancestors for all humans is presented.

The environmental conditions during the last ice age and their impact on human migration are examined.

A discussion on the behavioral changes in humans around 60,000 to 70,000 years ago that allowed for survival and expansion.

The development of modern language and social networks as a critical factor in human success.

The Genographic Project, launched in 2005, aims to increase sample size and understand human migration patterns.

The project's public participation aspect, allowing individuals to test their own DNA and contribute to the study.

The Legacy Fund, a charitable entity that supports indigenous groups with educational and cultural projects.

The success of the Genographic Project with over 235,000 public participants and its impact on scientific understanding.

The importance of the project in documenting and preserving human genetic diversity and cultural heritage.

Transcripts

play00:26

these are a few of the languages

play00:27

that i've spoken little bits of over the

play00:30

course the last six weeks as i've been

play00:32

to

play00:32

17 countries i think i'm up to on this

play00:34

crazy tour i've been doing

play00:36

uh checking out various aspects of the

play00:38

project that we're doing that i'm going

play00:39

to tell you a little bit about later on

play00:41

and visiting some pretty incredible

play00:43

places

play00:44

places like mongolia cambodia new guinea

play00:48

south africa tanzania twice i was here a

play00:50

month ago

play00:52

and the opportunity to make a whirlwind

play00:55

tour

play00:56

of the world like that is utterly

play00:58

amazing for lots of reasons you see some

play01:00

incredible stuff

play01:01

and you get to make these spot

play01:03

comparisons between people all around

play01:05

the globe

play01:06

and the thing that you really take away

play01:08

from that the kind of surface

play01:09

thing that you take away from it is not

play01:12

that we're all one

play01:13

although i'm going to tell you about

play01:14

that but rather how different we are

play01:17

there is so much diversity around the

play01:19

globe six thousand different languages

play01:22

spoken by six and a half billion people

play01:24

all different colors shapes sizes

play01:26

you walk down the street in any big city

play01:27

you travel like that

play01:29

and you are amazed at the diversity in

play01:31

the human species

play01:33

how do we explain that diversity well

play01:36

that's what i'm going to talk about

play01:37

today is how we're using the tools of

play01:39

genetics

play01:40

population genetics in particular to

play01:43

tell us

play01:45

how we generated this diversity and how

play01:47

long it took

play01:48

now the problem of human diversity like

play01:51

all big scientific questions how do you

play01:52

explain something like that can be

play01:54

broken down into sub questions and you

play01:56

can

play01:56

ferret away at those little sub

play01:57

questions first one is uh really a

play02:00

question of origins do we all share

play02:02

a common origin in fact and given that

play02:04

we do

play02:05

and that's the assumption everybody i

play02:06

think in this room would make when when

play02:08

was that

play02:09

when did we originate as a species how

play02:10

long have we been diverging from each

play02:12

other

play02:13

and the second question is related but

play02:16

slightly different if we do spring from

play02:17

a common source

play02:18

how did we come to occupy every corner

play02:20

of the globe and in the process

play02:22

generate all of this diversity the

play02:23

different ways of life the different

play02:25

appearances the different languages

play02:26

around the world

play02:28

well the question of origins as with so

play02:30

many other questions in biology seems to

play02:32

have been answered by darwin

play02:33

over a century ago and the descent of

play02:34

man who wrote in each great region of

play02:36

the world the living mammals are closely

play02:37

related to the extinct species of the

play02:39

same region

play02:40

it's therefore probable that africa was

play02:42

formerly inhabited by extinct apes

play02:44

closely allied to the gorilla and

play02:45

chimpanzee

play02:46

and as these two species are now man's

play02:48

nearest allies it's somewhat more

play02:49

probable that our early progenitors

play02:51

lived on the african continent than

play02:52

elsewhere

play02:53

so we're done we can go home finish the

play02:56

origin question well not quite

play02:58

because darwin was talking about our

play03:00

distant ancestry our common ancestry

play03:02

with apes and it is quite clear

play03:05

that apes originated on the african

play03:06

continent around 23 million years ago

play03:08

they appear on the fossil record

play03:10

africa was actually disconnected from

play03:12

the other land masses at that time due

play03:13

to the vagaries of plate tectonics

play03:15

floating around the indian ocean

play03:17

bumped into eurasia around 16 million

play03:19

years ago and then we had the first

play03:20

african exodus as we call it the apes

play03:23

that left at that time ended up in

play03:24

southeast asia became the gibbons and

play03:26

the orangutans and the ones that stayed

play03:27

on in africa evolved into the guerrillas

play03:29

the chimpanzees and us so yes

play03:31

if you're talking about our common

play03:32

ancestry with apes it's very clear by

play03:34

looking at the fossil record we started

play03:36

off here

play03:36

but that's not really the question i'm

play03:38

asking i'm asking about

play03:40

our human ancestry things that we would

play03:42

recognize as being like us

play03:44

if they were sitting here in the room

play03:46

they were peering over your shoulder

play03:47

you wouldn't leap back like that what

play03:50

about our human ancestry because if we

play03:52

go far enough back

play03:53

we share a common ancestry with every

play03:54

living thing on earth

play03:56

dna ties us all together so we share

play03:58

ancestry with barracuda and bacteria

play04:00

and mushrooms if you go far enough back

play04:03

over a billion years

play04:04

what we're asking about though is human

play04:06

ancestry how do we study that well

play04:08

historically it has been studied

play04:10

using the science of paleoanthropology

play04:12

digging things up out of the ground

play04:14

and largely on the basis of morphology

play04:16

the way things are shaped

play04:17

often skull-shaped saying this looks a

play04:19

little bit more like us than that so

play04:21

this

play04:21

must be my ancestor this must be who i'm

play04:24

directly descended from

play04:26

the feel of paleoanthropology i'll argue

play04:28

gives us lots of fascinating

play04:30

possibilities about our ancestry but it

play04:32

doesn't give us the probabilities that

play04:34

we really want

play04:35

as scientists what do i mean by that

play04:37

you're looking at a great example here

play04:38

these are three extinct species of

play04:40

hominid potential human ancestors

play04:42

all dug up just west of here and aldo by

play04:44

gorge by the leaky family

play04:46

and they're all dating to roughly the

play04:47

same time from left to right we've got

play04:49

homo erectus homo habilis and

play04:50

australopithecus now called paranthropus

play04:52

boisei

play04:53

robust australopithecine three extinct

play04:56

species same place

play04:57

same time that means that not all three

play05:00

could be

play05:00

my direct ancestor which one of these

play05:02

guys am i actually related to

play05:04

possibilities about our ancestry but not

play05:06

the probabilities that we're really

play05:08

looking for

play05:10

well a different approach has been to

play05:11

look at morphology

play05:13

in humans using the only data that

play05:15

people really had at hand until quite

play05:17

recently

play05:17

again largely skull-shaped the first

play05:19

person to do this systematically

play05:21

was linnaeus carl von linney swedish

play05:24

botanist who in the 18th century took it

play05:26

upon himself to

play05:27

categorize every living organism on the

play05:29

planet you think you've got a tough job

play05:31

and he did a pretty good job he

play05:33

categorized about twelve thousand

play05:35

species in systemic naturai

play05:36

he actually coined the term homo sapiens

play05:38

means wise man in latin

play05:40

but looking around the world at the

play05:42

diversity of humans he said

play05:43

well you know we seem to come in

play05:45

discreet subspecies or categories

play05:48

and he talked about africans or and

play05:50

americans and asians and europeans in a

play05:52

blatantly racist category he termed

play05:54

monstrosus

play05:55

which basically included all the people

play05:56

he didn't like including imaginary folk

play05:59

like elves

play06:02

it's it's easy to dismiss this as the

play06:05

perhaps well-intentioned but ultimately

play06:07

benighted musings of an 18th century

play06:09

scientist

play06:10

working in the pre-darwinian era except

play06:13

if you had taken physical anthropology

play06:14

as recently as 20 or 30 years ago

play06:17

in many cases you would have learned

play06:18

basically that same classification of

play06:20

humanity human races

play06:22

that according to physical

play06:23

anthropologists of 30 40 years ago

play06:25

carlton is the best example

play06:28

had been diverging from each other this

play06:29

was in the post darwinian era for

play06:31

over a million years since the time of

play06:33

homo erectus

play06:34

but based on what data very little very

play06:37

little morphology and a lot of guesswork

play06:40

well what i'm going to talk about today

play06:42

what i'm going to talk about now is a

play06:44

new approach to this problem instead of

play06:45

going out and guessing about our

play06:47

ancestry digging things up out of the

play06:49

ground possible ancestors and

play06:51

saying on the basis of morphology which

play06:52

we still don't completely understand we

play06:54

don't know the genetic causes underlying

play06:55

most

play06:56

morphological variation what we need to

play06:59

do is turn the problem on its head

play07:00

because what we're really

play07:01

asking is a genealogical problem or a

play07:04

genealogical question

play07:06

what we're trying to do is construct a

play07:08

family tree for everybody alive today

play07:11

and as any genealogist will tell you

play07:13

anybody have

play07:14

member of the family or maybe you've

play07:15

tried to construct a family tree trace

play07:17

back in time you start in the present

play07:19

with relationships you're certain about

play07:20

you and your sibling share a parent in

play07:21

common

play07:22

you and your cousin share a grandparent

play07:24

and comment and you gradually trace

play07:25

further and further back into the past

play07:27

adding these ever more distant

play07:28

relationships but eventually

play07:30

no matter how good you are at digging up

play07:32

the church records and all that stuff

play07:34

you hit what the genealogists call a

play07:36

brick wall a point beyond which you

play07:38

don't know anything else about

play07:39

your ancestors and you enter this dark

play07:41

and mysterious realm we call

play07:43

history that we have to feel our way

play07:45

through with whispered guidance

play07:47

who were these people who came before we

play07:49

have no written record well

play07:51

actually we do written in our dna in our

play07:54

genetic code

play07:55

we have a historical document that takes

play07:56

us back in time to the very earliest

play07:58

days of our species

play08:00

and that's what we study now a quick

play08:02

primer on dna i suspect

play08:04

that not everybody in the audience is a

play08:05

geneticist it is a very long

play08:07

linear molecule a coded version of how

play08:10

to make another copy of you it's your

play08:12

blueprint

play08:13

it's composed of four subunits a c g and

play08:15

t we call them and it's the sequence of

play08:17

those sub units that that defines that

play08:18

blueprint

play08:20

how long is it well it's billions of

play08:21

these subunits in length

play08:23

a haploid genome we actually have two

play08:25

copies of all of our chromosomes

play08:26

haploid genome is around 3.2 billion

play08:28

nucleotides in length

play08:30

and the whole thing if you add add it

play08:32

all together is over 6 billion

play08:33

nucleotides long if you take all the dna

play08:35

out of

play08:36

one cell in your body and stretch it end

play08:38

to end

play08:39

it's around 2 meters long if you take

play08:42

all the dna out of every cell in your

play08:43

body and you stretch it

play08:44

end to end it would reach from here to

play08:46

the moon and back thousands of times

play08:48

it's a lot of information and so when

play08:51

you're copying

play08:52

this dna molecule to pass it on it's a

play08:54

pretty tough job

play08:56

imagine the longest book you can think

play08:58

of war and peace

play09:00

and now multiply it by a hundred and

play09:02

imagine copying that by hand

play09:04

and you're working away until late at

play09:06

night and you're very very careful

play09:07

you're drinking coffee and you're paying

play09:08

attention but occasionally

play09:10

when you're copying this by hand you're

play09:12

going to make a little typo a spelling

play09:13

mistake

play09:14

substitute an i for an e or a c for a t

play09:18

same thing happens to our dna as it's

play09:20

being passed on through the generations

play09:22

it doesn't happen very often we have a

play09:23

proofreading mechanism built in

play09:25

but when it does happen and these

play09:26

changes get transmitted down through the

play09:28

generations they become markers of

play09:30

descent if you share a marker with

play09:31

someone

play09:32

it means you share an ancestor at some

play09:34

point in the past

play09:35

the person who first had that change in

play09:36

their dna and it's by looking

play09:38

at the pattern of genetic variation the

play09:40

pattern of these markers and people all

play09:42

over the world

play09:43

and assessing the relative ages when

play09:45

they occurred

play09:46

throughout our history that we've been

play09:47

able to construct a family tree for

play09:49

everybody alive today these are two

play09:50

pieces of dna that we use quite widely

play09:52

in our work

play09:53

mitochondrial dna tracing a purely

play09:55

maternal line of descent you get your mt

play09:57

dna from your mother and your mother's

play09:58

mother

play09:59

all the way back to the very first woman

play10:01

the y chromosome the piece of dna that

play10:03

makes men

play10:04

men traces a purely patronal line of

play10:06

descent

play10:07

everybody in this room everybody in the

play10:10

world

play10:11

falls into a lineage somewhere on these

play10:13

trees

play10:15

now even though these are simplified

play10:16

versions of the real trees they're still

play10:18

kind of complicated so let's simplify

play10:20

them turn them on their sides combine

play10:21

them so that they look like a tree with

play10:22

the root at the bottom and the branches

play10:24

going up

play10:25

what's the take-home message well the

play10:28

thing that jumps out at you first is

play10:29

that the deepest lineages

play10:30

in our family trees are found within

play10:33

africa

play10:35

among africans that means that africans

play10:38

have been accumulating this mutational

play10:40

diversity

play10:41

for longer and what that means is that

play10:44

we originated

play10:45

in africa it's written in our dna every

play10:47

piece of dna we look at

play10:48

has greater diversity within africa than

play10:51

outside of africa

play10:52

and at some point in the past a subgroup

play10:54

of africans left the african continent

play10:56

to go out and populate the rest of the

play10:58

world now how recently do we share this

play11:01

ancestry was it

play11:02

millions of years ago which we might

play11:04

suspect by looking at all this

play11:06

incredible variation around the world

play11:08

no the dna tells a story that's very

play11:10

clear within the last 200 000 years

play11:13

we all share an ancestor a single person

play11:16

mitochondrial eve

play11:17

you might have heard about her in africa

play11:20

an african woman who gave rise to all

play11:21

the mitochondrial diversity in the world

play11:23

today

play11:24

but what's even more amazing is that if

play11:25

you look at the y chromosome side

play11:27

the male side of the story the y

play11:29

chromosome atom

play11:31

only lived around 60 000 years ago

play11:33

that's only about 2 000 human

play11:35

generations

play11:36

the blink of an eye in an evolutionary

play11:38

sense

play11:40

that tells us we were all still living

play11:41

in africa at that time

play11:43

this was an african man who gave rise to

play11:45

all the y chromosome diversity around

play11:47

the world

play11:47

it's only within the last 60 000 years

play11:49

that we have started to generate this

play11:50

incredible diversity we see around the

play11:52

world

play11:53

such an amazing story we're all

play11:55

effectively part of an extended african

play11:57

family

play11:59

now that seems so recent why didn't we

play12:01

start to leave

play12:02

earlier why didn't homo erectus evolve

play12:04

into separate species or subspecies

play12:06

rather human races around the world

play12:08

why was it that we we seem to have come

play12:10

out of africa so recently

play12:12

well that's a that's a big question

play12:14

these why questions particularly

play12:15

in genetics and the study of history in

play12:17

general are always the big ones the ones

play12:19

that are tough to answer and so

play12:21

when all else fails talk about the

play12:23

weather

play12:24

what was going on to the world's weather

play12:26

around 60 000 years ago well

play12:27

we were going into the worst part of the

play12:29

last ice age last ice age started

play12:31

roughly 120 000 years ago

play12:33

it went up and down and it really

play12:34

started to accelerate around 70 000

play12:36

years ago lots of evidence

play12:38

from sediment cores and the pollen types

play12:40

oxygen isotopes and so on

play12:42

we had the last glacial maximum around

play12:43

16 000 years ago

play12:45

but basically from 70 000 years on

play12:47

things were getting really tough

play12:49

getting very cold the northern

play12:50

hemisphere had

play12:52

massive growing ice sheets new york city

play12:55

chicago seattle all under a sheet of ice

play12:58

most of britain all of scandinavia

play13:00

covered by ice several kilometers thick

play13:03

now

play13:03

africa is the most tropical continent on

play13:06

the planet about 85 percent of it lies

play13:08

between cancer and capricorn

play13:10

and there aren't a lot of glaciers here

play13:11

except in the high mountains here in

play13:12

east africa

play13:14

so what was going on here we weren't

play13:15

covered in ice in africa

play13:17

rather africa was drying out at that

play13:19

time this is a paleoclimatological map

play13:22

of what africa looked like between 60

play13:24

and 70 000 years ago

play13:25

reconstructed from all these pieces of

play13:27

evidence that i mentioned before

play13:28

the reason for that is that ice actually

play13:31

sucks moisture out of the atmosphere if

play13:33

you think about antarctica it's

play13:34

technically a desert it gets so little

play13:36

precipitation

play13:37

so the whole world was drying out the

play13:39

sea levels were dropping

play13:41

and africa was turning to desert the

play13:42

sahara was much bigger then

play13:44

than it is now and the human habitat was

play13:47

reduced to just a few small pockets

play13:49

compared to what we have today the

play13:51

evidence from genetic data is that the

play13:53

human population around this time

play13:55

roughly 70 000 years ago crashed to

play13:57

fewer than 2

play13:58

000 individuals we nearly went extinct

play14:00

we were hanging on

play14:01

by our fingernails and then something

play14:04

happened

play14:05

great illustration of it look at some

play14:07

stone tools the ones on the left are

play14:09

from

play14:09

africa from around a million years ago

play14:12

the ones on the right

play14:13

were made by neanderthals our distant

play14:15

cousins not our direct ancestors

play14:17

living in europe and they date from

play14:18

around 50 or 60 000 years ago

play14:21

now the the risk of offending any

play14:23

paleoanthropologists or

play14:24

physical anthropologists in the audience

play14:27

basically

play14:28

there's not a lot of change between

play14:30

these two

play14:31

stone tool groups ones on the left are

play14:33

pretty similar to the ones on the right

play14:34

we are in a period of long

play14:36

cultural stasis from a million years ago

play14:39

until around 60 to 70 thousand years ago

play14:41

the tool styles don't change that much

play14:43

the evidence is that the human way of

play14:44

life didn't change that much

play14:46

during that period but then 50

play14:49

60 70 000 years ago somewhere in that

play14:51

region all hell breaks loose

play14:54

art makes its appearance the stone tools

play14:56

become much more finely crafted

play14:58

the evidence is that humans begin to

play15:00

specialize in particular prey species at

play15:02

particular times of the year

play15:03

the population size started to expand

play15:06

probably according to what many

play15:07

linguists believe

play15:08

fully modern language syntactic language

play15:10

subject verb object that we use to

play15:12

convey complex ideas

play15:14

like i'm doing now appeared around that

play15:15

time we became much more social the

play15:17

social networks expanded

play15:20

this change in behavior allowed us to

play15:22

survive these worsening conditions

play15:24

in africa and they allowed us to start

play15:26

to expand

play15:28

around the world we've been talking at

play15:31

this conference about african success

play15:32

stories

play15:33

well you want the ultimate african

play15:35

success story look in the mirror

play15:37

you're it the reason you're alive today

play15:39

is because of those changes

play15:41

in our brains that took place in africa

play15:43

probably somewhere in the region where

play15:44

we're

play15:45

sitting right now around 60 70 000 years

play15:47

ago

play15:49

allowing us not only to survive in

play15:50

africa but to expand out of africa in

play15:52

early coastal migration along the south

play15:54

coast of asia leaving africa around 60

play15:56

000 years ago

play15:57

reaching australia very rapidly by 50

play15:59

000 years ago

play16:00

slightly later migration up into the

play16:02

middle east these would have been

play16:03

savannah hunters

play16:05

so those of you who are going on one of

play16:06

the post-conference tours you'll get to

play16:08

see what a real savannah is like and

play16:09

it's basically a meat locker

play16:11

people who would have specialized in

play16:13

killing the animals hunting the animals

play16:15

on

play16:15

those meat lockers savannahs moving up

play16:17

following the grasslands into the middle

play16:19

east around 45 000 years ago

play16:21

during one of the rare wet phases in the

play16:23

sahara

play16:24

migrating eastward following the

play16:25

grasslands because that's what they were

play16:27

adapted to live on

play16:28

and when they reached central asia they

play16:30

reached what was effectively a step

play16:32

super highway a grassland superhighway

play16:35

the grasslands at that time this is

play16:36

during the last ice age stretched

play16:38

basically from germany all the way over

play16:39

to korea

play16:40

and the entire continent was open to

play16:42

them entering europe around 35

play16:44

000 years ago and finally a small group

play16:46

migrating up through the worst

play16:47

weather imaginable siberia inside the

play16:50

arctic circle during the last ice age

play16:52

temperatures of minus 70 minus 80 even

play16:54

minus 100 perhaps

play16:56

migrating into the americas ultimately

play16:59

reaching that final frontier

play17:00

an amazing story and it happened first

play17:03

in africa the changes that allowed us to

play17:05

do that

play17:06

the evolution of this highly adaptable

play17:07

brain that we all carry around with us

play17:09

allowing us to create novel cultures

play17:11

allowing us to develop the diversity

play17:13

that we see on a whirlwind trip like the

play17:16

one i've just been on

play17:18

now that story i just told you is

play17:21

literally

play17:21

a whirlwind tour of how we populated the

play17:23

world the great paleolithic wanderings

play17:25

of our species

play17:27

and that's the story that i told a

play17:28

couple of years ago in my book the

play17:30

journey of man and the film

play17:31

that we made the same title and

play17:34

as we were finishing up that film it was

play17:36

co-produced with national geographic

play17:38

i started talking to the folks at ng

play17:40

about this work

play17:41

and they got really excited about it

play17:44

they you know

play17:44

they liked the film but they said you

play17:45

know we really see this as kind of the

play17:47

next

play17:48

wave in the study of human origins where

play17:50

we all came from

play17:51

using the tools of dna to uh map the

play17:54

migrations around the world

play17:55

you know study of human origins is kind

play17:57

of in our dna and we want to take it to

play17:59

the next level what do you want to do

play18:00

next

play18:01

which is a great question to be asked by

play18:03

national geographic

play18:04

and i said well you know what i've

play18:07

sketched out here is just that

play18:08

it is a very coarse sketch of how we

play18:10

migrated around the planet

play18:12

and it's based on a few thousand people

play18:13

we've sampled from

play18:15

you know a handful of populations around

play18:16

the world studied a few genetic markers

play18:19

and there are lots of gaps on this map

play18:21

we've just connected the dots

play18:22

what we need to do is increase our

play18:24

sample size by an order of magnitude or

play18:27

more

play18:27

hundreds of thousands of dna samples

play18:29

from people all over the world

play18:31

and that was the genesis of the

play18:32

genographic project

play18:34

the project launched in april of 2005 it

play18:37

has three core components

play18:38

obviously science is a big part of it

play18:41

the field research that we're doing

play18:42

around the world with indigenous peoples

play18:44

people who've lived in the same location

play18:46

for a long period of time retain a

play18:47

connection to the place where they live

play18:49

that many of the rest of us have lost so

play18:52

my ancestors come from all over northern

play18:53

europe i live in the eastern seaboard of

play18:55

north america when i'm not traveling

play18:57

where am i indigenous to nowhere really

play18:59

my genes are all jumbled up but there

play19:00

are people who retain that link to their

play19:02

ancestors

play19:03

that allows us to contextualize the dna

play19:06

results

play19:07

that's the focus of the field research

play19:08

centers that we've set up all over the

play19:10

world 10 of them top population

play19:11

geneticists

play19:13

but in addition we wanted to open up

play19:14

this study to anybody around the world

play19:16

how often do you get to participate in a

play19:18

big scientific project

play19:20

the human genome project or a mars rover

play19:22

mission in this case you actually can

play19:24

you can go onto our website

play19:26

nationalgeographic.com

play19:27

genographic you can order a kit you can

play19:29

test your own dna

play19:31

and you can actually submit those

play19:32

results to the database and tell us a

play19:34

little bit about your genealogical

play19:36

background

play19:36

have the data analyzed as part of the

play19:38

scientific effort

play19:40

now this is all a non-profit enterprise

play19:43

and so the money that we raise after we

play19:44

cover the cost of doing the testing and

play19:46

making the kit components gets plowed

play19:47

back into the project the majority going

play19:49

to something we call the legacy fund

play19:51

it's a charitable entity basically a

play19:54

grant giving entity that

play19:55

gives money back to indigenous groups

play19:57

around the world for educational

play19:59

cultural projects initiated by them they

play20:01

apply to this fund

play20:02

in order to do various projects and i'll

play20:04

show you a couple of examples

play20:05

so how are we doing in the project we've

play20:06

got about 25 000 samples collected from

play20:08

indigenous people around the world

play20:10

the most amazing thing has been the

play20:12

interest on the part of the public 210

play20:14

000 people have ordered these

play20:15

participation kits since we launched two

play20:17

years ago

play20:18

which has raised around five million

play20:20

dollars the majority of which

play20:22

at least half is going back into the

play20:23

legacy fund we've just awarded the first

play20:25

legacy grants totaling

play20:26

around five hundred thousand dollars

play20:28

projects around the world documenting

play20:30

world poetry in sierra leone preserving

play20:31

traditional weaving patterns in gaza

play20:33

language revitalization in tajikistan

play20:36

etc etc

play20:38

so the project is going very very well

play20:40

and i urge you to check out the website

play20:42

and

play20:43

watch this space thank you very much

play21:14

do

play21:29

you

play21:56

do

play22:11

you

Rate This
β˜…
β˜…
β˜…
β˜…
β˜…

5.0 / 5 (0 votes)

Related Tags
Human GeneticsPopulation DiversityMitochondrial EveY-Chromosome AdamAfrican OriginsGlobal MigrationPaleolithic WanderingsGenographic ProjectCultural EvolutionDNA Analysis