The Truth About Tranexamic Acid Serum

Summary

This video script delves into the efficacy of tranexamic acid in skincare, particularly for melasma and hyperpigmentation. It explains how this synthetic lysine derivative, traditionally used to stop bleeding, can reduce pigmentation by inhibiting UV-induced inflammation. The script reviews various clinical studies on topical formulations, highlighting variable results and the importance of formulation for penetration. It also discusses additional benefits like improved barrier function and reduced redness, suggesting tranexamic acid's potential as a cost-effective, soothing, and multifaceted skincare ingredient.

Takeaways

• 🧪 Tranexamic acid is a synthetic derivative of lysine, an amino acid, used since the 1960s to stop bleeding and treat conditions like menaga and melasma.
• 💊 When taken orally, tranexamic acid is effective in treating melasma, a skin condition characterized by hyperpigmentation and abnormal blood vessel formation due to hormonal and UV exposure.
• 🌞 The drug works against melasma by inhibiting the activation of plasminogen in keratinocytes, which is triggered by UV exposure and leads to increased pigment production.
• 🧴 Topical application of tranexamic acid in skincare products has shown variable results in clinical studies, suggesting that the formulation and concentration are crucial for effectiveness.
• 🔬 Tranexamic acid's polar nature raises questions about its ability to penetrate the skin effectively, which may limit its impact on hyperpigmentation when applied topically.
• 🛠️ Multiple clinical studies have tested different formulations of topical tranexamic acid, with varying results, indicating that the formulation plays a significant role in its effectiveness.
• 🌈 Tranexamic acid may also improve skin barrier function and reduce redness, offering benefits beyond hyperpigmentation, such as relief for conditions like rosacea.
• 🛑 The treatment of melasma and hyperpigmentation typically requires a multi-modal approach, combining various topical ingredients and treatments to target different aspects of pigmentation.
• 💡 Tranexamic acid's role in skincare is not limited to pigment reduction; it also has anti-inflammatory properties and may improve overall skin radiance and evenness.
• 💡 Sun protection is essential for managing melasma and preventing the recurrence of hyperpigmentation, as UV rays are a significant contributing factor.
• 🛒 There are several skincare products on the market containing tranexamic acid, such as the Polish Choice discoloration Repair Serum and the minimalist 3% tranexamic acid serum, which also contain other beneficial ingredients like niacinamide and mandelic acid.

Q & A

What is Tranexamic Acid?

Tranexamic acid is a synthetic lysine derivative, an amino acid, which has been used for decades since the 1960s to stop bleeding. It's often used to treat menaga (heavy periods) and hyperpigmentation conditions like melasma.

How does Tranexamic Acid work for melasma?

Tranexamic acid works for melasma by targeting plasminogen in keratinocytes at the bottom layer of the epidermis. It prevents the release of inflammatory mediators triggered by UV exposure, which leads to increased melanogenesis and hyperpigmentation.

What is the role of plasminogen in the context of melasma?

Plasminogen is a target for tranexamic acid in keratinocytes. Its activation by UV exposure leads to the release of inflammatory mediators, which in turn trigger an increase in melanogenesis and hyperpigmentation.

Are there any clinical studies on the topical application of Tranexamic Acid for skin conditions?

Yes, there are several clinical studies examining different formulations of topical tranexamic acid, such as 3% cream, 5% gel, and 3% solution, applied for 12 weeks each. The results vary, with some showing promise for improving melasma and others showing no effect.

How important is the formulation of topical Tranexamic Acid products?

The formulation is crucial because the structure of tranexamic acid is polar, and it may not reach a meaningful concentration in the skin without proper formulation, which could affect its effectiveness in suppressing UV-mediated pigment production.

Can Tranexamic Acid improve skin conditions other than hyperpigmentation?

Yes, Tranexamic acid can improve barrier function and has been examined for conditions like rosacea, offering symptomatic relief for sensitivity, redness, and burning. It also inhibits angiogenesis, reducing abnormal blood vessel formation and facial redness.

What is the difference between skin lightening and skin brightening?

Skin lightening refers to a reduction in melanin pigment, while skin brightening is an overall improvement in skin radiance and luminosity, which can result from better barrier function, moisturization, and a reduction in inflammation leading to redness.

How does Tranexamic Acid affect the skin's barrier function?

Tranexamic acid can improve the skin's barrier function by inhibiting PAR-2, which helps in reducing sensitivity and irritation, and can be beneficial for conditions like rosacea and melasma by limiting the penetration of irritating substances.

What are some of the products available in the market that contain Tranexamic Acid?

There are products like the Polish Choice Discoloration Repair Serum with 3% tranexamic acid and 5% niacinamide, and the Minimalist 3% Tranexamic Acid Serum with mandelic acid and other ingredients to improve skin tone and address hyperpigmentation.

What are some considerations when using topical Tranexamic Acid for skin care?

It's important to set realistic expectations, as topical tranexamic acid may not be a one-size-fits-all solution. It shows promise but requires more research. It's generally well-tolerated and may play a supporting role in a multi-modal approach to treating skin conditions like melasma and rosacea.

Why is sun protection important when dealing with skin conditions like melasma and rosacea?

Sun protection is crucial because UV rays are a significant contributing factor to these conditions. They can drive issues like hyperpigmentation and inflammation, worsening or causing the recurrence of conditions like melasma, rosacea, and post-acne marks.

Outlines

00:00

🧪 Tranexamic Acid in Skincare: Myth or Reality?

This paragraph delves into the efficacy of tranexamic acid in skincare, questioning its legitimacy and discussing its chemical nature and medical history. Tranexamic acid, a synthetic derivative of lysine, has been used since the 1960s to manage bleeding conditions like menaga. It's also been found to treat melasma, a skin condition characterized by hyperpigmentation, by addressing the hormonal and UV-induced triggers that cause pigment production. The paragraph explains the mechanism by which tranexamic acid works in the skin, focusing on its interaction with keratinocytes and plasminogen, and its potential to reduce inflammation and pigmentation. Clinical studies with varying results are mentioned, emphasizing the importance of formulation for effective topical application.

05:02

🌿 Beyond Pigment Reduction: Tranexamic Acid's Broader Benefits

The second paragraph expands on the potential benefits of topical tranexamic acid beyond hyperpigmentation. It discusses the compound's ability to improve skin barrier function, particularly for conditions like rosacea, by inhibiting PAR-2 and reducing inflammation. The paragraph also touches on the importance of addressing skin redness and barrier health in conjunction with pigmentation issues for a more comprehensive skincare approach. A case study is highlighted, demonstrating significant improvements in facial redness using a DIY 10% tranexamic acid solution, suggesting its potential as a cost-effective treatment option.

10:05

🛡️ Tranexamic Acid as a Skincare Ingredient: Considerations and Options

This paragraph explores the role of topical tranexamic acid in skincare routines, emphasizing its potential to soothe irritation and redness associated with conditions like rosacea and post-acne marks. It discusses the importance of formulation and tolerance, suggesting that tranexamic acid may be a viable option for those seeking to improve skin radiance and evenness. The paragraph also mentions the synergistic effects of combining tranexamic acid with other ingredients like niacinamide and antioxidants, which can enhance its benefits. Two specific products are reviewed, illustrating the availability and potential applications of topical tranexamic acid in skincare.

15:06

🌟 Setting Realistic Expectations for Topical Tranexamic Acid

The final paragraph focuses on setting realistic expectations for the use of topical tranexamic acid. It acknowledges the need for more research but recognizes the ingredient's potential as a supporting therapy for conditions like melasma and rosacea. The importance of a multi-modal approach to treating these chronic skin conditions is stressed, along with the necessity of ongoing skin protection, particularly from UV rays. The paragraph concludes by reiterating the importance of sun protection and the role of tranexamic acid as part of a comprehensive skincare regimen.

Keywords

💡Tranexamic Acid

Tranexamic acid is a synthetic derivative of the amino acid lysine, which has been used medically since the 1960s to control bleeding. In the context of the video, it is highlighted for its off-label use in treating melasma, a skin condition characterized by hyperpigmentation. The video discusses how, when applied topically or taken orally, tranexamic acid can help reduce the appearance of melasma by inhibiting the activation of plasminogen in keratinocytes, thus reducing inflammation and pigment production.

💡Hyperpigmentation

Hyperpigmentation refers to an increase in melanin production, leading to darker patches on the skin. In the video, it is explained that hyperpigmentation can be caused by factors like UV exposure, hormonal changes, and inflammation. Melasma is a specific type of hyperpigmentation discussed in the script, and the role of tranexamic acid in treating it is a central theme of the video.

💡Melasma

Melasma is a common skin condition that results in brown or gray-brown patches on the face, often due to hormonal changes, UV exposure, and genetic predisposition. The video emphasizes that melasma is responsive to oral tranexamic acid and that topical application may also offer benefits, although the effectiveness can vary based on the formulation.

💡Keratinocytes

Keratinocytes are skin cells found in the epidermis, the outermost layer of the skin. The script explains that these cells contain plasminogen, which is targeted by tranexamic acid to prevent the release of inflammatory mediators that trigger pigment production, thus playing a role in the treatment of melasma and hyperpigmentation.

💡Plasminogen

Plasminogen is a protein in the skin cells that, when activated, leads to the release of inflammatory mediators. The video describes how tranexamic acid works by inhibiting the activation of plasminogen in keratinocytes, thereby reducing inflammation and pigment production associated with melasma and hyperpigmentation.

💡Inflammatory Mediators

In the video, inflammatory mediators such as prostaglandins and leukotrienes are mentioned as substances that, when released, can trigger an increase in melanogenesis, leading to hyperpigmentation. Tranexamic acid is shown to help by preventing the increase in these mediators.

💡Melanogenesis

Melanogenesis is the process by which melanin, the pigment responsible for skin color, is produced. The script explains that UV exposure and inflammation can increase melanogenesis, leading to hyperpigmentation. Tranexamic acid is discussed as a potential treatment that can help reduce this pigment production.

💡Post-inflammatory Hyperpigmentation

Post-inflammatory hyperpigmentation refers to the dark marks left on the skin after inflammation, such as from acne or bug bites. The video mentions that tranexamic acid may help reduce this type of hyperpigmentation by inhibiting the same pathways that lead to pigment production.

💡Clinical Studies

Clinical studies are mentioned in the video as the source of evidence for the effectiveness of topical tranexamic acid. The script cites various studies with different formulations and concentrations of tranexamic acid applied topically for 12 weeks, with results indicating variable effectiveness in improving melasma.

💡Formulation

The term 'formulation' in the video refers to the specific combination of ingredients and their concentrations in a skincare product. It is emphasized that the effectiveness of topical tranexamic acid depends on its formulation, as different formulations may affect the product's ability to penetrate the skin and deliver the active ingredient to the target area.

💡Barrier Function

Barrier function refers to the skin's ability to protect itself from external irritants and maintain hydration. The video discusses how tranexamic acid may improve barrier function, which can be beneficial for conditions like rosacea and for overall skin health, including reducing redness and improving skin tone.

💡Anti-inflammatory

Anti-inflammatory effects are properties of certain substances, like tranexamic acid as discussed in the video, that can reduce inflammation in the body. The script explains that tranexamic acid's anti-inflammatory properties may help reduce redness and improve conditions such as rosacea and melasma.

💡Niacinamide

Niacinamide, also known as vitamin B3, is highlighted in the video as an ingredient that complements the effects of tranexamic acid. It is known for its benefits in reducing dark spots, redness, and improving the moisture barrier. The video mentions a product containing both niacinamide and tranexamic acid, suggesting a synergistic effect on skin health.

Highlights

Tranexamic acid is a synthetic lysine derivative historically used to stop bleeding and treat heavy periods.

When taken orally, tranexamic acid helps treat melasma, a skin condition characterized by hyperpigmentation.

Melasma is triggered by hormones, UV exposure, and visible light, causing abnormal pigmentation and blood vessel formation.

Tranexamic acid works by inhibiting the activation of plasminogen in keratinocytes, reducing inflammation and pigment production.

Clinical studies show varying results for topical tranexamic acid's effectiveness in treating melasma.

The formulation of topical tranexamic acid is crucial for its effectiveness, with some studies showing promise and others showing no effect.

Tranexamic acid may improve barrier function and provide symptomatic relief for conditions like rosacea.

It inhibits angiogenesis and reduces vascular endothelial growth factor, which can help with redness and barrier function.

Topical tranexamic acid can be beneficial for skin brightening and even skin tone, beyond just reducing pigmentation.

A case study showed significant improvement in facial redness using a 10% tranexamic acid solution applied topically.

Tranexamic acid is generally well-tolerated topically, which is important for conditions that can be worsened by irritation.

Topical tranexamic acid may offer improvement in hyperpigmentation, redness, and barrier function, but more research is needed.

Polish Choice's discoloration Repair Serum contains 3% tranexamic acid and other beneficial ingredients like niacinamide.

The Minimalist's 3% tranexamic acid serum includes mandelic acid and other components to enhance skin texture and penetration.

Tranexamic acid's effectiveness in skincare is not a one-size-fits-all solution and should be part of a multi-modal approach.

Sun protection is essential when using tranexamic acid for melasma and other skin conditions, as UV rays can worsen symptoms.

Transcripts

does tranexamic acid in skincare even

work or is it just a big scam I really

feel as though this is something we need

to talk about more in depth so that you

guys don't go down the wrong path with

your skincare routines and add things

that may or may not do anything first of

all what the heck is tranexamic acid

it's a synthetic lysine derivative

lysine's an amino acid and it's been

used for decades in decades since like

the' 60s to stop bleeding it's

specifically it's often used to treat

menaga which is the medical term for

well heavy periods but come to find out

given orally like a pill that you take

by mouth tranexamic acid is actually

quite helpful in treating a skin

condition where you have

hyperpigmentation and that skin

condition is known as melasma and I have

a lot of videos about melasma on my

channel so if you deal with it you need

to check those out so you have more

insight into what's going on

hyperpigmentation

as well as an increase in abnormal blood

vessel formation all triggered by

hormones irritating things and UV

exposure from the Sun as well as visible

light from the Sun but why might a drug

used to treat bleeding work for malasma

in your epidermis at the very bottom

layer of your epidermis the epidermis is

the top part of your skin at the very

bottom part of the top part you have uh

skin cells called keratin aides those

keratin aides have something called

plasminogen which is the target for

tranexamic acid now in contrast to its

mechanism for stopping bleeding here

it's a little bit different because as

it turns out a big reason why

hyperpigmentation is driven by UV

exposure is the activation of this

plasminogen via keratinocytes that leads

to the release of inflammatory mediators

like prostaglandin and lucat trines that

subsequently trigger increase in

melanogenesis AK pigment production

underscoring a hyperpigmentation this is

not only an issue for melasma but also

for other types of hyperpigmentation

like post-inflammatory hyperpigmentation

those dark marks that might be left

behind on your skin after say acne heals

or a bug bite heals so tranexamic acid

interrupts that and basically Works to

stop UV mediated

hyperpigmentation by preventing the

increase in prostaglandins and lucrin so

Asma in particular responds well to oral

tranexamic acid as well as introducing

it directly into the skin via like micro

needling or some other sort of delivery

system where you are basically injecting

it into the skin locally but some people

are not going to be good candidates for

oral tranexamic acid it may not be

tolerable or feasible to have it

injected in so can it actually work when

you just apply it to the skin if you

just just look at the structure of

tranexamic acid you're going to be

skeptical if you know anything about

chemistry it's going to be like is that

actually going to get in it's polar so

depending on how it's formulated into

skincare products it may not reach a

meaningful concentration where it needs

to be to suppress UV mediated increases

in pigment production but we're willing

to try things anyways so there are

several clinical studies out there not a

ton okay not a ton looking at different

formulations of topical tranexamic acid

3% tranexamic acid cream applied

topically for 12 weeks 5% tranexamic

acid gel applied topically for 12 weeks

3% tranexamic acid solution applied for

12 weeks 5% liposomal tranexamic acid

applied for 12 weeks and then a 2%

formulation applied again for 12 weeks

you're noting a theme here these are all

done 12 weeks which is good to have some

consistency um of all these studies I've

just mentioned the results are varying

some show promise for improving melasma

when applied topically others show no

effect so the results are variable and

really what it tells us is that we have

to strongly take into account the

overall formulation now I pointed this

out in my other videos before but when

it comes to treating

hyperpigmentation malas Asma

specifically but really any type of

hyperpigmentation rarely is it going to

be the case if at all that it is a

single best treatment to get rid of the

condition usually especially with

melasma almost always it's multi modal

approaches using topicals that combine

different ingredients that Target

different aspects of what leads to

hyperpigmentation and in the case of

melasma also address that underlying

vascular component there also energy

based devices like lasers light based

devices that may be employed chemical

peels and then of course we cannot

neglect aggressive sun protection

especially for melasma so to say is

tranexamic acid worth it for

hyperpigmentation melasma just in terms

of improving the pigment issue the

hyperpigmentation it really all depends

on what else you're doing formulation is

key speaking of formulation a product

can contain other ingredients that

Target other aspects of the pigment

producing Pathway to augment the chances

that you notice an appreciable

difference in dark spots as well as

ingredients that enhance penetration as

well as enhan skin cell turnover things

like lactobionic acid a polyhydroxy acid

or mandelic acid or salicylic acid but

what if I told you that topical

tranexamic acid doesn't just Target

increase pigment production and benefits

may be obtained outside of solely

reducing melanin pigment abnormal

melanin pigment production um because

when it comes to discoloration a lot of

people laser focus in on on the pigment

but there can be overlying skin changes

and other background skin changes going

on that lead to an overall appearance of

discoloration and addressing those

things leads to a brightening effect

things like dull skin as well as

background redness that in some skin

tones especially when overlapped on top

of hyperpigmentation can look more like

discoloration tranexamic acid bya

inhibition of something called par 2

actually can improve barrier function

and this has specifically been examined

not for melasma or hyperpigmentation but

rather for rosacea a condition

characterized by increased sensitivity

to things that come in contact with the

skin and a background problem with the

Skin Barrier so remember our barrier um

the outermost layer of our skin it's

serves to limit penetration of things

that are irritating people who have

rosacea they have a bit of an impaired

barrier and they have other things going

on in their skin that make them very

very sensitive topical tranexamic acid

can actually improve barrier function

offering symptomatic relief for people

with rosacea from the symptoms of

burning stinging sensitivity as well as

redness things that address barrier

function not only are going to be

helpful for rosacea but they also can be

helpful for molas and hyperpigmentation

because things that are irritating to

the skin can aggravate hyperpigmentation

as well tranexamic acid Works also to

inhibit angiogenesis new blood vessel

abnormal blood vessel formation reduces

vascular endothelial growth factor

necessary for these you know dilated

blood vessels to come in and form and it

also reduces facial redness because it

reduces certain inflammatory markers so

topical tranexamic acid actually may be

beneficial not just from the perspective

of improving hyperpigmentation but also

redness and barrier function by

improving barrier function it can help

with improving overall skin tone a lot

of people get hung up on skin lightening

reduction in melanin pigment but a lot

of what might also benefit them is skin

brightening which skin brightening

differs from skin lightening in that

it's not a reduction in pigment but it's

an overall Improvement in skin Radiance

luminosity and that can come about as a

result of an improvement in barrier

function and moisturization of the skin

overall clearer um and more even skin

tone just by light scattering and a

reduction in inflammation that leads to

redness so that's another thing to

really think about it's not just the

hyperpigmentation it's anti-redness and

it is helpful for barrier function but

we do still have that issue of optimal

formulation penetration does it actually

get in and do what it's supposed to do a

really striking case study of one

patient we've talked about

rosacea and now inappropriate use of

strong steroid creams on the face can

actually cause um a type of rosacea

called steroid rosacea where you can get

persistent facial redness dilated blood

vessels that's what I'm showing you here

on this woman's face from this case

report tranexamic acid is something that

is given to stop bleeding and comes in a

little vial a liquid they they made a

10% solution of tranexamic acid from

that so you know not a skincare product

that you buy in the store um gave it to

the patient in a little plastic

container that was protected from light

told the patient make sure you store

this at room temperature it's actually

stable for 90 days had the patient get a

cotton swab dip it in the solution and

apply it to the skin twice a day look at

the Improvement that this individual got

so that's really interesting I I would

love to see this pursued more because

tranexamic acid is a really cheap drug

inexpensive drug if you could just do

this and give it to a p you know if your

doctor would be willing to try this out

either for redness or for

hyperpigmentation it's it's very

compelling as a potential easy coste

effective therapeutic modality so all of

me telling you oh yeah formulations

really important for penetration and

everything this patient got good results

just dipping on into the uh 10% solution

and smearing it on with a cotton swap

it's generally well tolerated as a

topical and will'll say that topical

tranexamic acid is generally well

tolerated which is important because

whether it be rosacea or

hyperpigmentation anything that is

irritating can worsen either of those

conditions making the redness the dark

spots much worse so where does topical

tranexamic acid fit into this thing is

it something that you should consider

introducing into your skin care routine

well you know if it's not broken don't

fix it but topical tranexamic acid may

may okay offer some improvement not just

in hyperpigmentation whether it be

melasma or post-inflammatory

hyperpigmentation but also may help calm

down redness and may help with your

moisture barrier if you're somebody who

deals with a lot of facial redness

irritation you may find actually that

topical tranexamic acid is very soothing

right it cuts down on things like Incan

6 and it has an anti-inflammatory effect

and it may help with your barrier

function limiting penetration of things

that are irritating into the skin I

think it is a compelling topical for

people who deal with post acne marks

whether it be redness and or

hyperpigmentation it's not the only one

out there it's not the most well studied

for these things but it's compelling and

it is an option and it is available

there are a few products on the market

that use tranexamic acid one of them I

reviewed a few years ago for you guys

from Polish Choice their discoloration

Repair Serum this has 3% tranexamic acid

but it also has 5% niacinamide so as it

turns out you guys already know who

watch a lot of my videos niacinamide

like tranexamic acid is a good

ingredient for dark spots redness the

moisture barrier uh reducing sensitivity

it's anti-inflammatory all of these

things that tranexamic acid may do

depending on the formulation iCal

niacinamide has a lot more research

supporting that it does so I like that

that's included cuz remember also what I

said about treating dark spots

hyperpigmentation it's not usually just

one ingredient having multiple

ingredients in there that Target

different arms of the pigment pathway

really can lend better results and

niacinamide specifically works for

hyperpigmentation because it slows down

the spread of those pigment packets that

are produced in the melanocytes to the

neighboring keratin sites so that's

totally different from how tranexamic

acid is going to be working for dark

spots tranexamic acid is going to be

working for dark spots by hopefully

making its way down to the junction

between the epidermis and the dermis

targeting the plasminogen pathway in

those keratinocytes suppressing UV from

the Sun

mediated uh increases in prostaglandin

and lucat Trine that lead to

melanogenesis and hyperpigmentation so

totally different mechanisms they

complement one another so I like that

now the discoloration defense serum also

has uh biku which is an antioxidant that

may also help along with these things in

combating inflammation in the skin it's

marketed as a discoloration defense

serum but overall I think it's also a

good option for people who deal with

facial redness and are simply seeking a

serum that may help improve overall skin

skin Radiance and E even out one's skin

tone like all of Polish Choice products

it's free of fragrance it's like a very

lightweight lotion you apply it maybe as

a first step in your morning or evening

skincare routine after cleansing to skin

while it's still a bit damp that really

can help maximize penetration of

ingredients um they they penetrate

better on damp skin allow it to absorb

fully and then apply sunscreen if you're

wearing it during the day or and or a

moisturizer on over if you like in the

evening but this particular product is

$55 is there a less expensive

alternative well one that I have tried

out that is is a good one that I would

also recommend comes from the brand

minimalist they have a tranexamic acid

three a 3% tranexamic acid serum um that

is like less than $12 in addition to the

tranexamic acid this particular serum

has mandelic acid which can help smooth

out the skin surface and allow for

better penetration of that tranexamic

acid it also has 0.5% cyc acid um which

is good for exfoliating the pores but

also works well for helping to improve

hyperpigmentation it has some

anti-inflammatory properties to it so

overall this particular serum I think is

especially good for people who have

post- acne redness post- acne dark marks

but it might also be helpful for people

have rosacea and I know what you're

thinking like yeah but mandelic acid

salicylic acid certainly those are

completely off the table when it comes

to rosacea right like we're not supposed

to use stuff like that and that's not

true yes people with rosacea do have

exquisitly sensitive skin and

exfoliating acids like salicylic acid

and even mandelic acid possibly can end

up being too irritating but they also

can be beneficial for rosacea because

they can help cut down on deodex mites

which are a big problem with rosacea so

they may also help in that regard

smoothing out the skin surface and with

consistent use that ultimately helps

with better barrier function provided

you tolerate which with rosacea is going

to be a very individualized outcome so

that's another great option um it also

has oat kernel extract in it which is

very moisturizing hydrating and soothing

and it has um sodium hyaluronate the

salt is of Hy IC acid which is hydrating

so those things alone are are definitely

also going to complement potential

benefits to the moisture barrier from

tranexamic Acid um and ultimately help

out with just evening out skin tone so

those are two options right there all

that to say it's important to set your

expectations with regards to Tropic

tropical with regards to topical

tranexamic acid it's not a slam dunk and

it it it shows promise but more research

is needed I think it's a generally well

tolerated ingredient though so it makes

sense that a lot of people appreciate

Improvement in skin tone using it

there's a mechanism there and it is very

effective when given systemically to

treat melasma and this may be you know

TR topical tranexamic acid is kind of

viewed at least for melasma and

hyperpigmentation as an option maybe as

a bridging therapy because you know

things like hydroquinone which is the

gold standard for melasma we don't like

to continue that indefinitely and it can

be irritating so we like to bridge the

person onto something that's kind of as

a maintenance treatment and then come

back to hydroquinone if we need to and

so during those bridging time periods

tranexamic acid topically may be an

option especially if the patient is not

able to take systemic tranexamic acid

that you know it's contraindicated due

to their medical history the other thing

about setting your expectations is to

know that with melasma and rosacea these

are chronic skin conditions while these

products ingredients treatments

modalities Etc do help in um improving

symptoms and controlling they don't cure

and so you always have to be babysitting

these conditions they don't you know

they they typically come back and it

requires you to always be on you know

two or three steps ahead whether it be

melasma whether it be uh rosacea whether

it be post acne dark marks or red marks

sun protection is key UV rays drive a

lot of of these issues not the only

cause of these problems not the only

contributing factor but a big one and

one that you always need to be be on top

of and mindful of in order for any of

these things to offer any sort of

benefit and to prevent the conditions

from worsening and or recurring more

frequently all right y'all I hope this

was informative to you all regarding

topical tranexamic acid where we're at

as far as what it's been shown to be

helpful for the limitations setting your

expectations knowing it's not a

oneandone this is the best the worst but

likely plays a supporting role and

explains why a lot of people do in fact

note Improvement in their skin when

using it if you guys enjoyed this video

give it a thumbs up share it with your

friends and as always don't forget

sunscreen And subscribe I'll talk to you

guys tomorrow bye he

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