ETY Cardiology T2T Mentorship Program,Heart in Systemic Disease

Summary

Professor Gila Nas of Suez Canal University Egypt discusses the critical link between systemic diseases and cardiovascular health. Chronic kidney disease, diabetes, endocrine disorders, and thyroid conditions are highlighted as major contributors to heart complications. The presentation emphasizes the importance of a holistic approach to managing systemic diseases to prevent cardiovascular issues, advocating for a preventive strategy with a focus on healthy lifestyle choices.

Takeaways

• 💼 The presentation is by Gila Nas, a professor of Cardiology, emphasizing the importance of understanding the relationship between systemic diseases and cardiovascular health.
• ⏱ Heart disease is a leading cause of death, killing one person every 33 seconds worldwide, highlighting the urgency of addressing heart health.
• 🔍 Systemic diseases can affect the heart through various mechanisms, including increased demands on the heart, causing arrhythmias, affecting heart structure, or promoting cardiovascular disease.
• 🌐 Chronic kidney disease is a systemic condition that has a definite impact on the heart, causing hypertrophy and other structural changes.
• 🚨 Diabetes is a common endocrine and metabolic disease with a well-known relationship to heart disease, causing coronary artery disease, cardiomyopathy, and other complications.
• 🔄 Hyperthyroidism and hypothyroidism are endocrine disorders that can lead to various cardiac issues, including atrial fibrillation and heart failure.
• 🧬 Other systemic diseases, such as malignant carcinoid, acromegaly, and hemochromatosis, can also have significant effects on the heart, leading to valve disease, heart failure, and arrhythmias.
• 🥗 Nutritional deficiencies and obesity are associated with heart disease, with vitamin deficiencies leading to heart failure and obesity causing cardiomyopathy.
• 🤒 Systemic diseases like rheumatoid arthritis and systemic lupus erythematosus can cause pericarditis, myocarditis, and thrombosis, impacting heart function.
• 💊 A holistic approach to managing systemic diseases is necessary to address their cardiovascular implications, with a focus on prevention.
• 🏃‍♂️ The European Society of Cardiology promotes a healthy lifestyle with the equation '03514 530', encouraging no tobacco, walking 3 km daily, eating five portions of fruits and vegetables, and maintaining healthy blood pressure and lipid levels.

Q & A

What is the Heart Academy of the Egyptian Society of Cardiology?

The Heart Academy of the Egyptian Society of Cardiology is a collaboration between Egypt, Tunisia, and Yemen, focused on the study and treatment of heart diseases.

How frequently does heart disease kill a person according to the transcript?

Heart disease kills one person every 33 seconds, as mentioned in the transcript.

Who is Gila Nas and what are her affiliations?

Gila Nas is a professor of Cardiology at Suez Canal University in Egypt, head of the scientific council of the Egyptian Board of Cardiology, a board member of the Egyptian Society of Cardiology, and a representative for the Africa continent in the International Society of Cardiovascular Disease Prevention.

Why is it important to understand the relationship between systemic diseases and cardiovascular health?

Understanding the relationship is important because systemic diseases can affect the heart in various ways, such as increasing demands on the heart, causing arrhythmias, affecting the heart's structure, or promoting cardiovascular disease.

How does chronic kidney disease impact the heart according to the transcript?

Chronic kidney disease affects the heart by causing hypertrophy, leading to changes in the heart's structure, and is associated with various complications that are well known.

What is the relationship between diabetes and heart disease as described in the transcript?

Diabetes is closely associated with heart disease, causing coronary artery disease, cardiomyopathies, congestive heart failure, and arrhythmias due to factors like hyperglycemia, free fatty acids, and insulin resistance, which lead to oxidative stress, vasel constriction, inflammation, and thrombosis.

How does hyperthyroidism affect the heart?

Hyperthyroidism can lead to super ventricular tachycardia (SVT), atrial fibrillation (AF), and hypertension, affecting the heart's function and rhythm.

What impact does hypothyroidism have on the heart according to the transcript?

Hypothyroidism can cause bradycardia, dilated cardiomyopathy, and heart failure, impacting the heart's rate and function.

What are some other systemic diseases mentioned in the transcript that can affect the heart?

Other systemic diseases mentioned include malignant carcinoid, acromegaly, hemochromatosis, Anderson-Fabry disease, and sarcoidosis, each affecting the heart in different ways such as causing heart failure, arrhythmias, and valvular issues.

What is the significance of the equation '03514 530' mentioned in the transcript for a healthy lifestyle?

The equation '03514 530' stands for a healthy lifestyle where '0' represents no tobacco, '3' means walking 3 km daily or 30 minutes of moderate activity, '5' suggests taking five portions of fruits and vegetables, '1' is for maintaining blood pressure and lipid levels with total cholesterol less than 5 mmol/L and LDL less than 3 mmol/L, and the second '0' is for avoiding overweight and diabetes.

How does the transcript suggest managing systemic diseases with cardiovascular implications?

The transcript suggests a holistic approach to managing systemic diseases with cardiovascular implications, emphasizing the need for prevention and adherence to a healthy lifestyle as described by the '03514 530' equation.

Outlines

00:00

💓 Systemic Diseases and Their Impact on Cardiovascular Health

The first paragraph introduces the speaker, Professor Gila Nas, and emphasizes the importance of understanding the relationship between systemic diseases and cardiovascular health. It discusses how various systemic diseases, including chronic kidney disease and endocrine/metabolic disorders like diabetes and hyperthyroidism, can affect the heart through different mechanisms such as increased demands, arrhythmias, structural changes, and promoting cardiovascular diseases. The paragraph also highlights the specific impact of diabetes on the heart, including diabetic cardiomyopathy, endothelial dysfunction, arterial stiffness, and atherosclerosis.

05:02

🚑 Systemic Conditions Associated with Heart Complications

The second paragraph delves into other systemic diseases that have cardiovascular implications, such as malignant carcinoid, acromegaly, hemochromatosis, and Anderson-Fabry disease. It outlines how these conditions can lead to heart failure, arrhythmias, and other complications. The paragraph also touches on the impact of nutrition-related issues like malnutrition and vitamin deficiencies on the heart, as well as the effects of obesity and multi-system diseases like rheumatoid arthritis and systemic lupus on cardiac health.

10:04

🌟 Holistic Management and Prevention of Systemic Disease-Related Heart Issues

The concluding paragraph stresses the need for a holistic approach to managing systemic diseases with potential cardiovascular implications. It presents a preventive equation from the European Society of Cardiology, emphasizing the importance of a healthy lifestyle, including no tobacco use, regular physical activity, a balanced diet rich in fruits and vegetables, maintaining healthy blood pressure and lipid levels, and avoiding overweight and diabetes. The speaker summarizes the key points and thanks the audience for their attention.

Keywords

💡Heart Disease

Heart disease refers to a range of conditions that affect the heart's structure and function. In the video, it is highlighted as a leading cause of death, killing one person every 33 seconds. The script emphasizes the importance of understanding the relationship between systemic diseases and heart health, as various systemic conditions can increase the risk of heart disease.

💡Systemic Diseases

Systemic diseases are illnesses that affect the entire body, rather than being confined to a specific area. The video discusses how these diseases can impact the cardiovascular system, causing conditions such as arrhythmias, hypertrophy, and promoting coronary heart disease. Examples from the script include chronic kidney disease, diabetes, and thyroid disorders.

💡Chronic Kidney Disease

Chronic kidney disease (CKD) is a progressive loss of kidney function over time. The script mentions CKD as a systemic disease that has a definite impact on the heart, causing structural changes like hypertrophy and contributing to complications that are well known in the medical community.

💡Diabetes

Diabetes is a metabolic disorder characterized by high blood sugar levels. In the video, diabetes is discussed as a common endocrine and metabolic disease with a very well-known relationship to heart disease. It causes complications such as coronary artery disease, cardiomyopathy, and congestive heart failure through mechanisms like oxidative stress, inflammation, and thrombosis.

💡Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle that makes it harder for the heart to pump blood effectively. The script describes diabetic cardiomyopathy as an impact on the heart muscle and vessels, leading to endothelial dysfunction, arterial stiffness, and coronary artery calcification.

💡Thyroid Disorders

Thyroid disorders refer to conditions that affect the thyroid gland's ability to produce hormones. Hyperthyroidism and hypothyroidism are mentioned in the script as causing specific cardiac issues like atrial fibrillation and bradycardia, respectively, which are linked to systemic endocrine diseases.

💡Atherosclerosis

Atherosclerosis is a condition where plaque builds up inside the arteries, leading to reduced blood flow. The video script explains that diabetes can accelerate atherosclerosis, leading to complications in the vascular system and contributing to heart disease.

💡Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease that primarily affects joints but can also have cardiovascular implications. The script describes how it can lead to pericarditis, coronary arteritis, and conduction abnormalities, impacting heart health.

💡Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is another autoimmune disease that can affect various organs, including the heart. The video script discusses SLE's potential to cause pericarditis, myocarditis, thrombosis, and other heart-related complications.

💡Obesity

Obesity is a medical condition involving excessive body fat. The script highlights obesity as a systemic disease that can lead to cardiomyopathy and heart failure. It is referred to as 'Obesity heart disease,' indicating its significant impact on cardiovascular health.

💡Holistic Approach

A holistic approach in the context of the video refers to considering the entire person, including all aspects of their health, when managing systemic diseases. The script concludes with the need for such an approach to address the cardiovascular implications of systemic diseases effectively.

💡Preventive Approach

A preventive approach in healthcare involves采取措施 to prevent disease or health problems before they occur. The video script references a formula from the European Society of Cardiology that emphasizes lifestyle factors such as no tobacco, regular exercise, a healthy diet, and maintaining healthy blood pressure and cholesterol levels as part of a preventive strategy against heart disease.

Highlights

Heart disease is the leading cause of death globally, killing one person every 33 seconds.

The presentation is focused on the relationship between heart and systemic diseases.

Systemic diseases can affect the heart through various mechanisms, including increased demand, arrhythmia, structural changes, and promoting coronary heart disease.

Chronic kidney disease has a significant impact on the heart, causing hypertrophy and other complications.

Endocrine and metabolic diseases, such as diabetes, are closely related to heart disease, causing coronary artery disease and cardiopathies.

Diabetes affects the heart through hyperglycemia, free fatty acids, insulin resistance, and oxidative stress, leading to various complications.

Diabetic cardiomyopathy impacts the heart muscle and coronary vessels, leading to endothelial dysfunction and atherosclerosis.

Thyroid disorders, both hyperthyroidism and hypothyroidism, have distinct effects on the heart, including arrhythmias and heart failure.

Malignant carcinoid syndrome can lead to pulmonary valve disease and right-side heart failure.

Acromegaly and hemochromatosis are associated with heart failure and arrhythmias due to hormonal imbalances.

Nutritional deficiencies, such as vitamin deficiency, can lead to dilated cardiomyopathy and heart failure.

Obesity is a significant risk factor for heart disease, leading to conditions like 'Obesity heart disease'.

Rheumatoid arthritis and systemic lupus erythematosus can cause various heart complications, including pericarditis and myocarditis.

Amyloidosis, heart failure, and restrictive cardiopathies are associated with systemic diseases.

Sarcoidosis can lead to heart failure and various cardiac abnormalities.

Maran syndrome affects the aorta, potentially causing aortic aneurysm and dissection.

HIV infection can have detrimental effects on the heart, including cardiomyopathy and pericardial effusion.

A holistic approach is necessary for managing systemic diseases with cardiovascular implications.

Prevention is key, and the European Society of Cardiology provides a simple equation for a healthy lifestyle.

The importance of a healthy diet, regular exercise, and avoiding tobacco for cardiovascular health is emphasized.

Transcripts

hello

everybody Heart Academy of the Egyptian

Society of

Cardiology a collaboration between Egypt

Tunisia and

Yemen of course we know that heart

disease kills one person for every 33

second

interval

Nationwide my presentation is about

heart and systemic diseases

this is Gila Nas professor of Cardiology

sus Canal University Egypt head of

scientific Council of the Egyptian Board

of

Cardiology board member of the Egyptian

Society of

Cardiology Africa continent

representative in the international

Society of cardiovascular disease

prevention importance of understanding

the relationship between systemic dis

and the cardiovascular health is really

very

important there is a wide variety of

systemic diseases that may affect the

heart by a number of different

mechanisms including increasing demands

on the heart causing arhythmia affecting

the structure of the

heart or promoting cardiovascular

disease and therefore coronary heart

disease

chronic kidney disease is one form of

systemic disease that may affect the

heart as we all know that chronic kidney

disease has a definite relation between

heart and the impact of chronic kidney

disease on the structure causing

hypertrophy on the other mechanisms

causing a lot of changes and maybe the

complications of chronic kidney disease

is very well known

another common association with systemic

in disease include endocrine and

metabolic disease for example diabetes

very very

well-known

relationship causing coronary artery

disease causing cardiopathies congestive

heart

failure hyperthyroidism as well causing

super ventricular teic cardia AF

hypertension

hypothyroidism causing bradic card

dilated cardiopathy heart failure

pericardial

infusion the very wellknown relationship

between diabetes and heart causing by

the hyperglycemia free fatty acids

insulin resistance all these are doing

some form of oxidative

stress leading to vasel constriction

leading to inflammation thrombosis

and this very important manifestation of

diabetes on the heart the diabetic

cardiomyopathy affecting the heart

muscle the

vessels impact on coronary vessels

leading to endothelial

dysfunction leading to

stiffness increased arterial stiffness

leading coronary artery calcification

accelerated atherosclerosis

as well as doing autonomic impact

leading to reduced heart heart rate

variability increasing resting heart

rate

arhythmia and the impact on the cardiac

muscle leading to diastolic dysfunction

systolic

dysfunction this very ugly looking

artery leading to after

sclerosis and having a lot of of

complications on the vascular system

and this is very important and very ugly

complications leading to a lot of

complications as

well um uh also we do have other

complications as

we that the cardiovascular risk for

diabetes is very specific there is micro

albura this is massive bruttin UA the

platelet function

abnormalities the serum insulin the

thrombotic levels uh as well other

Association rather than diabetes the

hyper thyroidism the

hypothyroidism the

hyperthyroidism by a lot of mechanisms

leading to Super ventricular techic

cardia AF and

hypertension the

hypothyroidism the other side of the

coin leading to Brad cardia dilated

cardiopathy heart failure pericard

infusion

has an impact on this

[Music]

lipidemia the intimate thickness the

blood pressure and leading to heart

failure other association with systemic

diseases include the malignant

carcinoid the FOC chromosoma the

acromegaly the hemocromatosis

the Anderson fabri

disease malignant carcinoid leading to

TripIt pulmonary valve disease right

side heart failure f f chromosoma

leading to hypertension te cardia

congestive heart failure acromegaly

heart failure hemocromatosis heart

failure again arhythmia heart block

Anderson fabri disease leading to

arhythmia coronary artery disease heart

failure we all know that the

carcinoid affecting mainly the tripid

and Pulmonary V self disease leading to

heart failure by different

mechanisms on the other hand F

chromosoma meanly lead to

hypertension and techic

cardia leading to congestive heart

failure at the

end the acromag increase growth hormone

leading to sustained lipolysis inst

resistance increased liver and kidney

glucon

Genesis the increased reduced glucose

uptake in muscle

tissues this only lead to increased

lipid increased triglycerides decreased

HDL diabetes heart

failure other systemic disease include

nutrition malnutrition leading to

dilated cardiomiopathy heart

failure for example vitamin deficiency

as thamin deficiency leading to high

output heart failure D

cardiopathy hyper homos symia leading to

premature

atherosclerosis obesity definitely

leading to cardiopathy and heart failure

and this is the Obesity heart disease a

very common disease and we should

prevent it by many means we all know

that obesity has definitely an impact on

heart other multi-stem disease the

romatoid arites leading to peric carites

bicard effusion coronary arites mardes

vites Ser negative arthropathies leading

to aites aortic and mitro insufficiency

conduction

abnormalities systemic lupus pericard

Libman sex indoc cardit myoc carites

thrombosis both arterial and

Venus this is romatoid arthes as we know

it's definitely has a definite impact on

the heart leading to schic heart disease

maybe many patients of having rheumatoid

arthritis complain silently of uh of

symptoms of heart disease and many of

them experience SCH schic heart disease

in a silent

form systemic lupus very famous to cause

vascules peric carites Libman sex indoc

carites mic carites thrombosis which is

both arterial and

venous other syic diseases like Amy dois

heart disease heart failure restrictive

cardiopathy vular regurgitation

pericardial effusion sarcoidosis leading

to heart failure dilated restrictive

cardiopathies ventricular Aria heart

block Maran syndrome mainly affect aorta

leading to aortic aneurysm this

dissection aortic insufficiency mital

Val prolapse is a very common

Association D syndrome leading to aortic

and coronary aneurysm mitro

prolapse HIV infection mardes di

cardiopathy pericardial infusion a

effect

definitely have an impact on the heart

leading to heart failure restrictive

cardiomiopathy vular

regurgitation pericardial infusion we

have many kinds of amois primary

secondary

senile sosis of course leads a disease

which has an impact on heart leading to

heart failure dilated restrictive

cardiopathy ventricular Aria's heart

block Maran syndrome it has an impact on

the aorta as we can see there is may

lead to aortic aneurysm this is the

ascending aorta and may lead to

dissection aortic insufficiency materal

Val

prolapse and lately the

co we have noticed a lot of patients

having

hypertension and it has lead to

thrombosis thrombosed vessels and many

many other impact on the heart disease

as well so my conclusion is that a

holistic approach to managing systemic

disease under cardiovascular

implications is

needed and definitely we need to have an

A preventive approach by this very nice

equation coming from the European site

of

Cardiology

03514 530 people stay healthy then to

have certain characteristics zero stands

for no tobacco three walk 3 km daily or

30 minutes any moderate activity take

five portions of fruits and vegetables

they being antioxidants as well as

healthy diet 140 keep your blood

pressure um and P amount as well as the

lipid should be total cholesterol is

than 5 m moo LDL Less Than 3 m and zero

avoidance of overweight and diabetes

thank you very much we tried as we can

uh as we can do to put this subject in a

nutshell and in a very very um very few

words to explain the systemic disease

and its impact on heart disease thank

you very much