Metabolisme Vitamin C - Kelompok 3

Summary

This presentation covers Vitamin C metabolism, its sources, functions, and role in health. It highlights Vitamin C as a crucial water-soluble vitamin that aids immune function, collagen synthesis, and acts as an antioxidant. The body cannot synthesize Vitamin C, so it must be obtained from food like fruits and vegetables. The metabolism process involves absorption in the small intestine and transport to various tissues. Additionally, the presentation discusses the role of Vitamin C in wound healing and protecting cells from oxidative stress. Deficiency can cause scurvy, while excess intake can lead to side effects like diarrhea and iron poisoning.

Takeaways

• 😀 Vitamin C (ascorbic acid) is a water-soluble vitamin essential for various functions, including collagen synthesis, immune function, and as an antioxidant.
• 😀 Humans cannot synthesize vitamin C endogenously, so it must be obtained through diet, with major sources including vegetables, fruits, and animal products.
• 😀 Common sources of vitamin C include broccoli, peppers, cabbage, cauliflower, guava, pineapple, strawberries, oranges, and tomatoes.
• 😀 Vitamin C is absorbed actively in the small intestine, assisted by sodium-dependent transporters, and is then transported through the bloodstream to various tissues.
• 😀 Excess vitamin C that is not absorbed is degraded into hydroascorbic acid and excreted through urine if consumed in excess beyond the body's needs.
• 😀 The metabolism of vitamin C involves its active absorption, storage in non-fat tissues (e.g., adrenal glands, liver, kidneys, and leukocytes), and eventual excretion when levels exceed 80 mg/day.
• 😀 Vitamin C plays a vital role in wound healing through its involvement in collagen formation, which is crucial for regenerating damaged skin and tissues.
• 😀 Vitamin C assists in the production of hydroxylysine and hydroxyproline, essential components in the formation of collagen, contributing to tissue repair and regeneration.
• 😀 As an antioxidant, vitamin C helps neutralize reactive oxygen species (ROS) generated during exercise-induced metabolic processes, preventing oxidative stress and cell damage.
• 😀 Vitamin C deficiency can lead to diseases like scurvy, characterized by symptoms such as bleeding gums, joint swelling, and fatigue. Excessive intake can cause side effects such as diarrhea, anemia, and kidney stones.

Q & A

What is vitamin C and what are its primary functions in the body?

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that acts as a coenzyme, antioxidant, and reducer. It plays crucial roles in immune function, collagen synthesis, protecting immune cells from oxidative stress, and iron storage.

Why is vitamin C essential for humans, and how do humans obtain it?

Humans cannot synthesize vitamin C endogenously, unlike most animals. Therefore, it must be obtained from dietary sources, including fruits, vegetables, and animal products like meat and eggs.

What are some major food sources of vitamin C?

Major sources of vitamin C include vegetables like broccoli, peppers, and cabbage, fruits like guava, pineapple, strawberries, oranges, and tomatoes, and animal products such as milk, meat, and fish.

How is vitamin C absorbed and metabolized in the body?

Vitamin C is absorbed actively in the small intestine, aided by sodium-dependent vitamin C transporters. It enters the bloodstream and is distributed to tissues such as the adrenal glands, liver, and kidneys. Excess vitamin C is excreted in urine.

What happens if the body takes in more vitamin C than it needs?

Excess vitamin C that the body cannot use is converted into hydroascorbic acid and is eventually excreted through urine. If vitamin C levels exceed about 80 mg/day, the body activates this excretion process to avoid toxicity.

How does vitamin C contribute to collagen formation and wound healing?

Vitamin C is essential for collagen synthesis. It helps produce hydroxyproline and hydroxylysine, which are vital for collagen formation. Collagen is necessary for the regeneration of damaged skin cells and wound healing.

Can you explain the process of collagen synthesis involving vitamin C?

Vitamin C facilitates the formation of hydroxyproline and hydroxylysine, which are necessary for the production of procollagen. Procollagen is then glycosylated, forming a triple-helix structure that eventually matures into collagen after secretion from the cell.

How does vitamin C function as an antioxidant in the body?

Vitamin C neutralizes reactive oxygen species (ROS) by donating electrons, which reduces oxidative stress. This helps prevent cell damage, particularly in muscle tissue during physical exercise, and protects against lipid peroxidation.

What health risks are associated with a deficiency in vitamin C?

Vitamin C deficiency can lead to scurvy, characterized by bleeding gums, weakness, and joint swelling. It can also result in udis disease, which manifests as bleeding and fatigue.

What are the potential dangers of vitamin C overdose?

Excessive vitamin C intake can lead to diarrhea, hemolytic anemia, kidney stones, and iron overload, which can affect organs like the heart, liver, and pancreas.