Ternyata Begini Proses Pembuatan Obat Sirup di Pabrik || Proses Produksi Obat Sirup #indonesia

Summary

The video discusses the ongoing crisis of acute kidney failure in children, which is suspected to be caused by contaminated syrup medicine. The Indonesian Health Minister confirmed that the contamination includes dangerous chemicals such as ethylene glycol and diethylene glycol. The script then walks through the meticulous process of syrup production in pharmaceutical factories, detailing every step from formulation planning and quality checks to packaging and distribution. It emphasizes the importance of adhering to safety standards to prevent such health hazards and urges responsible use of medicines.

Takeaways

• 😀 The acute kidney failure cases in children are being linked to the consumption of syrup medicines contaminated with harmful chemicals.
• 😀 The Ministry of Health has confirmed that the chemicals ethylene glycol, diethylene glycol, and butylated hydroxyToluene (BHT) are responsible for the contamination in some syrups.
• 😀 A temporary ban has been placed on the circulation of syrup medicines in pharmacies until further research confirms which syrups are contaminated.
• 😀 The process of making syrup medicine starts with formulating the recipe, gathering data, and designing the formula with the help of a formulator.
• 😀 After the formulation, the syrup is validated and checked to ensure it meets quality standards before moving into production.
• 😀 Workers in the syrup production plant wear special clothing to maintain sterility and prevent contamination.
• 😀 Raw materials for syrup are sourced from pharmaceutical suppliers and undergo quality checks to ensure they meet the necessary safety and quality standards.
• 😀 Mixing the ingredients in large tanks and filtering the mixture are crucial steps to ensure a uniform and contaminant-free final product.
• 😀 Syrup is filled into bottles using automated machinery, sealed, and labeled efficiently to ensure high-volume production and accuracy.
• 😀 After filling and labeling, the syrup is further packaged into secondary and tertiary packaging before being sent to storage for quality control and final approval from BPOM.
• 😀 The final product is inspected by the Indonesian Food and Drug Authority (BPOM), which ensures that the syrup meets safety and quality regulations before being sold to the public.

Q & A

What is the cause of acute kidney failure in children as discussed in the script?

The script suggests that the acute kidney failure in children is possibly caused by the consumption of syrup-based medications contaminated with harmful chemicals, such as ethylene glycol, diethylene glycol, and butyl ether glycol.

What measures have been taken by the Ministry of Health regarding the distribution of syrup medications?

The Ministry of Health has temporarily banned the circulation of syrup medications in pharmacies until research is completed to identify which syrups are contaminated with dangerous chemicals.

What is the role of the 'formulator' in the production of syrup medications?

The formulator is responsible for designing the formula for the syrup medication, gathering data from various sources and research, and ensuring the formulation meets the required standards before production begins.

What is the importance of quality control during the production of syrup medications?

Quality control is crucial at every stage of the production process to ensure that the syrup medications meet the required standards, are free from contamination, and are safe for consumption.

How are the raw materials for syrup production sourced?

The raw materials for syrup production are usually ordered from pharmaceutical wholesalers, who ensure the delivery of quality ingredients to the production facility. These materials are checked for quality upon arrival.

What is the process of validation in syrup production?

The validation process involves verifying that the syrup formulation meets all required standards and specifications before it can proceed to production. This is done by the head of production and their team.

What role does sterilization play in the production of syrup medications?

Sterilization is essential to ensure that all equipment, such as bottles and raw materials, are free from contaminants that could affect the quality of the syrup. This includes thorough cleaning and sterilization of the bottles used for packaging.

What is the significance of the filtration process in syrup production?

Filtration is important to remove any residual particles or undissolved substances from the syrup, ensuring that the final product is clear and free of impurities that could affect its quality.

What happens after the syrup is bottled and sealed?

Once the syrup is bottled and sealed, it undergoes automatic labeling, then moves on to secondary packaging (like placing it in smaller boxes) and tertiary packaging (for transport), followed by another round of quality control checks.

What happens after the syrup medication passes the inspection by BPOM?

After passing the BPOM (Indonesian Food and Drug Authority) inspection, the syrup is deemed fit for marketing and distribution. It is then sent to pharmacies and healthcare facilities for sale and use by the public.