How Much Weed Is Needed To Overdose
Summary
TLDRThis video script delves into the complexities of cannabis consumption, focusing on debunking myths about overdose and exploring the drug's safety profile. Guided by Alicia's journey, it explains the body's endocannabinoid system, the differences between THC and CBD, and the importance of moderation. The script addresses the realities of cannabis edibles, the risks of synthetic cannabinoids, and the impact of legalization on societal perceptions. It emphasizes the need for education on safe consumption and the potential for dependency, advocating for a balanced approach to using cannabis responsibly.
Takeaways
- 🌿 **Cannabis Overdose Misconceptions**: The script clarifies that unlike opioids, cannabis does not typically lead to fatal overdoses due to its different interaction with the body's endocannabinoid system.
- 🧬 **Endocannabinoid System**: It plays a key role in moderating the effects of THC, ensuring that for most users, the effects are subtle and manageable rather than overwhelming.
- 🚫 **Synthetic vs. Natural**: Synthetic cannabinoids, despite being designed to mimic THC, can have much greater intensity and lead to severe and unpredictable health risks compared to natural cannabis.
- 📉 **CBD vs. THC**: The ratio of THC to CBD in cannabis strains can significantly influence the user's experience, with higher CBD content potentially offering more therapeutic benefits with less psychoactive effects.
- 🔍 **Personal Tolerance**: The script emphasizes the importance of understanding personal tolerance levels to cannabis, as reactions can vary greatly from person to person.
- 📚 **Education and Research**: Staying informed about the latest cannabis research and legal changes is essential for safe use, as the cannabis landscape is continually evolving.
- 🚫 **Avoid Unregulated Products**: The script advises against using synthetic cannabinoids and unregulated products, recommending natural, regulated cannabis products for safety.
- 💊 **Edibles and Dosage**: Consuming cannabis edibles requires caution due to their delayed effects and potential for overconsumption, leading to intense discomfort and anxiety.
- 🌱 **Cannabis Customization**: The industry offers products tailored to specific effects, leveraging varying ratios of THC and CBD to cater to consumer preferences.
- 🛑 **Non-Lethal Overdose**: While cannabis overdose is not typically fatal, it can lead to severe anxiety, paranoia, and panic attacks, which can have immediate mental health implications.
- 🏥 **Public Health and Safety**: There is a need for better public education on the effects of cannabis, safe consumption practices, and the importance of understanding personal tolerance levels.
Q & A
What is the main focus of the discussion in the script about marijuana?
-The main focus of the discussion is to dispel common myths associated with marijuana, particularly the concept of 'overdosing' on weed, and to explore the safety aspects and realities of cannabis consumption.
How does the script differentiate between an overdose of opioids and an overdose of cannabis?
-The script explains that while opioids can lead to fatal overdoses due to their ability to suppress respiratory function, the risk of a fatal overdose from cannabis is remarkably low because it does not affect the brainstem areas responsible for vital functions like breathing.
What role does the endocannabinoid system play in the effects of THC?
-The endocannabinoid system, which THC in cannabis interacts with, plays a key role in regulating physiological processes and ensures that the effects of THC are subtle and manageable for most users, rather than overwhelming.
What advice is given for those new to cannabis regarding consumption?
-The advice given is to 'start low and go slow,' which means starting with low doses and being patient to understand one's personal tolerance and the delayed onset of effects, especially for methods of consumption like edibles.
What are the differences between THC and CBD in terms of their effects on the user?
-THC is the primary psychoactive ingredient in cannabis that provides euphoric and intoxicating effects, while CBD is non-psychoactive and is known for its potential therapeutic benefits such as reducing anxiety and mitigating pain without producing a 'high.'
Why is it important to be cautious with cannabis edibles?
-Cannabis edibles require caution because the effects manifest with a notorious delay, leading many to underestimate their potency. The body processes cannabis differently when ingested, resulting in a more intense and prolonged experience.
What is the significance of the liver's role in metabolizing THC?
-The liver's role is significant because it converts THC into 11-hydroxy-THC, a metabolite that is more potent and has a longer half-life than THC itself, which can lead to unexpectedly intense effects if one consumes too much.
What are the key differences between natural cannabis and synthetic cannabinoids?
-Natural cannabis has a relatively benign safety profile with a low risk of serious adverse effects due to its long history of human consumption. Synthetic cannabinoids, on the other hand, are man-made chemicals that can bind to cannabinoid receptors with much greater intensity, leading to severe and unpredictable health risks.
What is cannabis use disorder (CUD) and what are its characteristics?
-Cannabis use disorder (CUD) is a condition characterized by an inability to reduce or control cannabis use despite negative consequences. It includes symptoms such as cravings, withdrawal symptoms upon cessation, and interference with personal obligations.
How does the script suggest maintaining a balanced relationship with cannabis?
-The script suggests maintaining balance by understanding the effects of cannabis on one's body and mind, recognizing the importance of moderation, setting clear boundaries for consumption, listening to one's body, and staying informed about the latest cannabis research and legal changes.
What are some practical tips for responsible cannabis consumption mentioned in the script?
-Some practical tips include 'start low and go slow,' understanding personal tolerance levels, avoiding synthetic cannabinoids and unregulated products, and sticking to natural, regulated cannabis products with tested and labeled information.
Outlines
🌿 Understanding Overdosing and Safety of Cannabis
This paragraph delves into the safety aspects of marijuana, focusing on the concept of 'overdosing' and its myths. It clarifies that an overdose, in medical terms, is the intake of a substance in excessive amounts leading to adverse health effects. Unlike opioids, cannabis does not have a high risk of fatal overdose due to its different interaction with the body's endocannabinoid system, which regulates physiological processes without affecting vital functions like breathing. The paragraph emphasizes the importance of understanding cannabis's unique safety profile and dispels myths about its dangers.
🍃 Exploring Cannabis Components and Their Effects
The second paragraph explores the nuances of cannabis, particularly the effects of THC and CBD. It explains that THC is the psychoactive component responsible for the 'high' associated with marijuana, while CBD is non-psychoactive and has potential therapeutic benefits. The paragraph discusses the importance of the THC to CBD ratio in influencing the overall experience, with higher THC strains producing more pronounced effects and higher CBD strains offering a more subdued experience. It also touches on the customization of cannabis products to cater to consumer preferences and the importance of starting with low doses and patience when trying cannabis for the first time.
🍫 The Risks and Realities of Cannabis Edibles
This paragraph narrates Alicia's experience with cannabis edibles, highlighting the delayed effects and the common mistake of overconsumption due to the misjudgment of potency. It explains that the body processes cannabis differently when ingested, leading to a more intense and prolonged experience compared to other methods of consumption. The paragraph emphasizes the importance of dosage and patience when consuming edibles, as well as the liver's role in metabolizing THC into a more potent form, 11-hydroxy-THC. It also dispels the myth of a lethal cannabis overdose, explaining that while cannabis can lead to uncomfortable symptoms, the risk of fatal overdose is exceptionally low.
⚠️ Synthetic Cannabinoids: The Dangers and Misunderstandings
The fourth paragraph takes a cautionary approach towards synthetic cannabinoids, which are man-made chemicals designed to mimic THC's effects but with much greater intensity. It contrasts these with natural cannabis, which has a relatively benign safety profile, and outlines the severe health risks associated with synthetic cannabinoids, including kidney injury, cardiovascular complications, and severe psychotic episodes. The paragraph also discusses the potential long-term effects and risks of dependency associated with regular and heavy cannabis use, highlighting the importance of responsible consumption and ongoing education about cannabis effects.
🏛 Legalization, Regulation, and the Evolving Perception of Cannabis
The final paragraph discusses the societal and legal shifts surrounding cannabis, particularly the impact of legalization and decriminalization efforts. It reflects on how these changes have normalized cannabis use and altered public perception, leading to a greater need for comprehensive education on cannabis effects, risks, and benefits. The paragraph also addresses the challenges of regulating the cannabis market to ensure product safety and consumer protection, emphasizing the importance of balancing accessibility with public health and safety. It concludes with Alicia's personal journey towards a balanced and safe relationship with cannabis, highlighting the need for self-awareness, moderation, and continuous education.
Mindmap
Keywords
💡Marijuana
💡Overdose
💡Endocannabinoid System
💡THC (Tetrahydrocannabinol)
💡CBD (Cannabidiol)
💡Synthetic Cannabinoids
💡Cannabis Use Disorder (CUD)
💡Legalization
💡Edibles
💡Personal Tolerance
💡Moderation
Highlights
Marijuana is at the forefront of discussions due to its impact on perceptions and laws.
The concept of 'overdosing' on marijuana is often misunderstood and shrouded in myths.
An overdose in medical terms refers to intake beyond recommended levels leading to adverse effects, not just fatal outcomes.
Unlike opioids, cannabis has a remarkably low risk of fatal overdose.
The body's endocannabinoid system regulates physiological processes without affecting vital functions like breathing.
Cannabis does not induce the same lethal risk as substances that depress the central nervous system.
The experience of a 'high' from cannabis varies greatly from person to person due to individual differences.
The recommended approach for new cannabis users is 'start low and go slow' to understand personal tolerance.
THC and CBD are key components of cannabis with distinct effects; THC is psychoactive, while CBD is not.
Different strains of cannabis with varying THC to CBD ratios can influence the overall experience.
Edibles have a notorious delayed effect, leading to overconsumption and intense discomfort.
The liver metabolizes THC into a more potent form, 11-hydroxy-THC, which can lead to severe effects if overconsumed.
The likelihood of a fatal overdose from cannabis is exceptionally low due to its interaction with the brain.
Non-lethal overdose symptoms from cannabis can be distressing and have mental health implications.
Synthetic cannabinoids, despite being marketed as alternatives, pose significant health risks due to their increased potency.
Cannabis use disorder (CUD) is a condition characterized by an inability to control cannabis use despite negative consequences.
Long-term cannabis use can impact cognitive functions and has potential effects on brain development in younger users.
Legalization and decriminalization of cannabis have altered public perception and societal norms.
Legal access to cannabis ensures product testing and clear labeling, which is beneficial for consumer protection.
A balanced and safe cannabis journey requires mindfulness, self-awareness, and ongoing education.
Practical tips for responsible cannabis consumption include starting with low doses and understanding personal tolerance levels.
Transcripts
Altering perceptions and laws alike, marijuana is at the forefront of many discussions these
days. In order to unpack some of the safety aspects surrounding this drug, we’ll follow
Alicia through her weed journey and dispel some of the common myths associated with the drug.
The concept of "overdosing" on weed, often shrouded in misconceptions and myths,
will be the focus of today’s discussion. With Alicia as our guide, we'll dissect what it
means to overdose, how cannabis interacts with our bodies, and the realities versus the myths
of cannabis consumption. Unlike substances such as opioids, where overdose definitions
are stark and often fatal, cannabis presents a different spectrum of effects and risks.
Let’s start with a basic definition. What does overdose mean? The concept of an overdose is
often misunderstood, with many associating it exclusively with fatal outcomes. However,
in the medical community, an overdose refers to the intake of a substance in quantities
greater than are recommended or generally practiced, leading to adverse health effects.
This can vary significantly across different substances. For instance, opioids, due to their
ability to suppress respiratory function, have a well-documented risk of fatal overdose. Cannabis,
on the other hand, interacts with the body in a fundamentally different way. According to studies,
while it's possible to consume cannabis in amounts that exceed comfortable or safe levels, the risk
of a fatal overdose is remarkably low compared to opioids or alcohol. This distinction is crucial in
understanding the unique safety profile of cannabis and its compounds.
In Alicia's journey into the world of cannabis, understanding what an overdose means is an
important step. Traditional notions of overdosing don’t align neatly with cannabis use. Why? Well,
the body's endocannabinoid system, which is what the THC in weed interacts with,
plays a key role in regulating physiological processes without directly influencing the
brainstem areas responsible for vital functions such as breathing.
This biological safeguard explains why, despite cases of overconsumption,
cannabis does not induce the same lethal risk as substances
that can depress central nervous system activity to a life-threatening degree.
While the discomfort and anxiety of consuming too much cannabis can
be distressing, these experiences are fundamentally different from the dire,
often life-threatening consequences of opioid or alcohol overdose.
This distinction is vital not only for users like Alicia to understand but also
for shaping public health messages and harm reduction strategies. As cannabis
becomes more integrated into societal norms, dispelling these kinds of myths is essential
for policymakers and users alike to make sure they stay informed and know how to safely use the drug.
Alicia's first foray into the world of cannabis was a journey filled with anticipation and
curiosity. Surrounded by friends in a comfortable setting, she lit up a joint and embarked on this
new experience. She expected a wave of relaxation and a touch of euphoria – common expectations
fueled by pop culture. However, the reality of her first encounter with THC – the main
psychoactive component in cannabis – was both enlightening and a tad underwhelming.
This discrepancy between expectation and experience is one of the nuanced effects
of cannabis, coming from the body's endocannabinoid system. This biological
system plays a pivotal role in moderating the effects of THC, ensuring that, for most users,
these effects are subtle and manageable rather than overwhelming. But everyone’s
body is different, and this is why there is no one “high” that all cannabis users experience.
The endocannabinoid system is a complex network of receptors and neurotransmitters
that regulate tons of physiological processes – including mood, appetite,
and pain sensation. THC's interaction with this system is what leads to the "high" associated
with cannabis use. Unlike substances that may produce immediate and overwhelming effects, THC's
engagement with the endocannabinoid system is more akin to a gentle nudge rather than a forceful
push. This results in a range of experiences that can vary greatly from person to person.
“Start low and go slow" is a recommended approach for those new to cannabis. This
approach prioritizes low doses and patience to understand one's personal tolerance and
the delayed onset of effects, which is especially relevant for methods of consumption like edibles.
After her initial brush with weed, Alicia's curiosity led her to explore
some of the nuances of cannabis’ components, particularly THC (tetrahydrocannabinol) and
CBD (cannabidiol). THC is the primary psychoactive ingredient that provides
the euphoric and intoxicating effects associated with marijuana use. In contrast,
CBD is non-psychoactive and has been touted for its potential therapeutic benefits, including
reducing anxiety and mitigating pain without producing a "high." This is why CBD can be found
in products like coffees and teas, baked goods, personal care and wellness products, and more.
As Alicia experimented with different strains, she quickly realized that the ratio of THC to
CBD could significantly influence her overall experience. This realization
was a turning point for her. Strains with a higher THC to CBD ratio tended
to produce more pronounced psychoactive effects, which, while enjoyable to some,
could lead to discomfort or anxiety in others, especially novices like Alicia.
Conversely, strains with a higher CBD content offered a more subdued experience,
potentially alleviating stress and anxiety without the intense
euphoria or potential paranoia associated with high THC strains.
All this talk about THC and CBD ratios leads us to a broader conversation about cannabis
customization and its therapeutic potential. The cannabis industry has seen a surge in products
tailored to specific effects, leveraging varying ratios of THC and CBD to cater to consumer
preferences for relaxation, creativity, pain relief, or minimal psychoactivity.
One evening, Alicia's journey with cannabis took a memorable turn. After years of hearing about them,
she finally decided to experiment with edibles. Unlike smoking or vaping, where the effects
manifest almost immediately, there is a notorious delay with edibles, leading many to underestimate
their potency. Alicia, unfamiliar with this delayed effect, consumed more than the recommended
serving size, expecting instant gratification. This common mistake among edible newcomers set
the stage for a night of intense, and we mean intense, discomfort. Why? Well, the body processes
cannabis differently when ingested, resulting in a more intense and prolonged experience.
This distinction is crucial… unless you want to spend hours dealing with unpleasant consequences.
The effects of the edibles crept up on Alicia unexpectedly, transforming what was intended to be
a relaxing night into an overwhelming ordeal. She experienced heightened anxiety, disorientation,
and an uncomfortable sense of paranoia – symptoms that are significantly less common or intense with
other methods of consumption. Both dosage and patience are crucial when delving into the world
of cannabis edibles. There’s a critical difference in how THC is metabolized when ingested, leading
to a more potent and longer-lasting effect, as THC is converted into 11-hydroxy-THC in
the liver – a metabolite that is more potent and has a longer half-life than THC itself.
Remember: “start low and go slow.” This approach is vital for avoiding
the discomfort and negative experiences associated with overconsumption while
ensuring you don’t experience the effects of “weed overdose.”
Let’s dive a little deeper. The concept of a lethal overdose is a significant concern
when discussing any substance use, including cannabis. However, when it comes to cannabis,
the discussion is wrapped in all sorts of myths and misunderstandings. The notion that
one can die from consuming too much cannabis is a topic fraught with misinformation. Scientific
research suggests that while cannabis can lead to uncomfortable and sometimes severe adverse
effects, the likelihood of a fatal overdose is exceptionally low. As we mentioned in
the intro, this is because of the way THC interacts with the brain. Unlike opioids,
which can suppress the brain's ability to control vital functions like breathing,
THC does not affect these critical brainstem areas. This fundamental
difference significantly reduces the risk of a lethal outcome from overconsumption of cannabis.
While Alicia had experienced over-consuming edibles and facing an uncomfortable ordeal,
it was not life-threatening. The absence of cannabinoid receptors
in the brainstem areas responsible for controlling vital life-support
functions explains why there has never been a documented case of a fatal cannabis overdose.
But here’s the thing. Addressing the myth of lethal overdose is not meant
to trivialize the potential negative impacts of cannabis use. Non-lethal overdose symptoms,
such as severe anxiety, paranoia, and panic attacks, can be profoundly distressing and
have immediate mental health implications. Plus, these experiences can deter individuals
from further cannabis use and contribute to stigmatization and misinformation.
Remember, the liver converts THC to 11-hydroxy-THC, a more potent form of the
cannabinoid, which can lead to unexpectedly intense effects if one consumes too much.
This biochemistry plays a crucial role in why individuals might experience severe (but still
non-lethal) symptoms, once again highlighting the need for patience and respect for recommended
dosages. Alicia's ordeal is a textbook example of how exceeding one's threshold can lead to a
night of distress, and can be categorized as an experience close to “overdosing” on weed,
given that, medically speaking, not every overdose is lethal.
Let’s talk about those non-lethal overdose symptoms in terms of public
health and safety. Emergency rooms and medical professionals are increasingly
encountering individuals presenting with acute cannabis intoxication,
particularly in regions where cannabis has been legalized or decriminalized. While these
encounters are rarely life-threatening, they require resources and attention and show that
there’s a real need for better public education on the effects of cannabis,
safe consumption practices, and the importance of understanding personal tolerance levels.
Now, our exploration of cannabis and its effects takes a more cautionary turn when delving into
the realm of synthetic cannabinoids. Unlike the natural compounds found in the cannabis plant,
synthetic cannabinoids are man-made chemicals designed to mimic the effects of THC,
the primary psychoactive component of cannabis. However, the similarities often end there.
Synthetic cannabinoids, sometimes misleadingly marketed as "safe" or "legal" alternatives to
cannabis, can bind to the same cannabinoid receptors in the brain but with much greater
intensity. This increased potency raises significant health risks, leading to severe and
unpredictable effects. Several studies have shown the dangers associated with these substances,
including acute kidney injury, cardiovascular complications, and severe psychotic episodes,
which starkly contrast the relatively benign safety profile of natural cannabis.
Alicia's curiosity about the broader spectrum of cannabis-related products led her to
learn about the risks associated with synthetic cannabinoids. Stories of individuals experiencing
extreme anxiety, violent behavior, and even life-threatening conditions after
using these substances scared her as she read them. Unlike natural cannabis,
which has a centuries-long history of human consumption with a relatively low
risk of serious adverse effects, synthetic cannabinoids have been
linked to numerous hospitalizations and, in some tragic cases, deaths.
As Alicia's relationship with cannabis evolved, so did her awareness of the
potential long-term effects and the risk of dependency. While cannabis is often
celebrated for its therapeutic benefits and relative safety compared to other substances,
regular and heavy use can lead to a condition known as cannabis use
disorder (CUD). This condition is characterized by an inability to reduce or control cannabis
use despite negative consequences. Yes, weed can be a medicinal ally… but it can
also be a potential source of dependency. The criteria for diagnosing CUD includes cravings,
withdrawal symptoms upon cessation, and interference with personal obligations.
Beyond the risk of dependency, there are potential long-term effects of frequent cannabis use.
Studies have shown that prolonged heavy use of cannabis can impact cognitive functions,
such as memory, attention, and decision-making. While these effects are generally reversible upon
cessation of use, they raise concerns about the impact of long-term cannabis consumption
on daily functioning and quality of life. There’s also the potential for altered brain
development in younger users, whose brains are still in a critical period of maturation.
How about the social and psychological aspects of long-term cannabis use? While cannabis can
enhance social interactions and provide relief from stress and anxiety in the short term,
dependency can lead to social withdrawal, reduced motivation,
and diminished interest in activities once found enjoyable. This paradoxical effect,
where the substance initially used for its positive effects becomes a hindrance to
well-being, is a critical consideration for anyone navigating their relationship with cannabis.
Now, let’s return to Alicia's story as we discuss some of the shifting
societal and legal paradigms. The recent wave of legalization and decriminalization efforts
across various jurisdictions has significantly altered the public's perception of cannabis.
These legal changes are often reflective of a growing acknowledgment of cannabis's
therapeutic potential. They’ve contributed to normalizing cannabis use in society. For Alicia,
living in an area where cannabis has been legalized meant navigating a new
world where purchasing cannabis came with the same ease and regulation as
buying alcohol. This shift in legal status removed a layer of stigma, but it also
introduced new challenges in understanding responsible use in a legal landscape.
The societal impacts of these legal changes are profound,
influencing everything from individual behavior to public health strategies. As cannabis becomes
more accepted, there’s a greater need for comprehensive education on its effects,
risks, and benefits. Alicia observed that with legalization, more people felt comfortable sharing
their experiences and seeking information, leading to a more informed community of users. However,
she also noticed a tendency to underestimate the risks associated with cannabis use,
particularly among younger individuals who might see legalization as an endorsement of safety.
And when it comes to regulating the cannabis market to ensure product safety and consumer
protection, things aren’t so straightforward. Alicia's experience highlights how legal access
to cannabis is beneficial as it comes with the assurance of product testing for contaminants
and clear labeling of THC and CBD content. However, the legal market also faces challenges,
such as the increase in unregulated products and the need for ongoing research into cannabis's
long-term effects. These issues reflect the evolving nature of cannabis regulation
and the continuous efforts required to balance accessibility with public health and safety.
Alicia had to take stock of her own perceptions of risk and responsibility
as she explored using weed in multiple forms. Finding balance with cannabis, as she discovered,
is a personal journey that requires mindfulness, self-awareness, and an ongoing commitment to
education. After navigating the highs and lows of her cannabis experiences, Alicia realized that the
key to a positive relationship with cannabis lay in understanding its effects on her body and mind,
and in recognizing the importance of moderation. This balance is not a one-size-fits-all
formula but a personalized approach that considers individual tolerance, lifestyle,
and the reasons behind cannabis use. For Alicia, this meant setting clear boundaries
for her consumption, such as limiting use to weekends or as a reward after meeting
personal and professional goals. This way, she could limit her dependence on it and
ensure that weed always enhanced rather than detracted from her quality of life.
Alicia also learned the importance of listening to her body and being attuned to the subtle signals
it provided in response to cannabis. Recognizing the signs of overconsumption early on, like her
increased anxiety or a feeling of unease, became crucial in adjusting her use to maintain balance.
Pursuing a balanced and safe cannabis journey, Alicia gathered several practical
tips that served as guideposts for responsible consumption. First and foremost was the adage,
"start low and go slow," especially important for newcomers to cannabis or those experimenting with
new products. Remember, this is all about beginning with low doses, particularly with
potent methods of consumption like edibles, which have a delayed onset of effects.
Understanding personal tolerance levels is another important key. Just as individuals vary in their
responses to caffeine or alcohol, reactions to cannabis differ from one person to another. Alicia
learned to pay close attention to how different strains and consumption methods affected her,
using this knowledge to make informed choices about her use. This personalized approach to
cannabis consumption is vital, as it respects the body's unique reactions to THC and CBD,
allowing for a more tailored and enjoyable experience.
Another big tip? Avoid synthetic cannabinoids and unregulated products – stick to natural,
regulated cannabis products. Legal markets offer the advantage of tested and labeled products,
providing transparency about strain, potency, and the presence of any additives. If you want
to avoid any of the nasty side effects of consuming weed, stick to the natural stuff.
Most importantly, though, keep educating yourself. Staying informed about the
latest cannabis research and legal changes is essential for safe use. The cannabis landscape
is continually evolving, with new studies shedding light on its effects, benefits,
and risks. If you follow these tips, you’ll end up having a positive relationship with weed, and,
most importantly, will avoid any of the nasty side effects of a non-lethal “weed overdose.”
Now for a deeper dive into the effects of weed,
check out “What Happens To Your Body When Smoking Weed.” Or watch this video instead!
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