ПОЛЫНЬ против РАКА: популярное народное средство. Реально ли работает? Артемизинин: научные факты

Summary

Dr. Igor Atabekov, an oncologist, discusses the potential benefits of Artemisinin, a compound found in wormwood, for cancer treatment. Known for its anti-malarial properties, Artemisinin is now being researched for its use in treating autoimmune diseases, inflammatory conditions, and various types of cancer. Although promising in preclinical studies, Artemisinin has limitations such as poor bioavailability. Its derivatives, such as Artesunate, are showing potential in clinical trials, improving patient outcomes and life expectancy. Dr. Atabekov stresses the importance of combining such treatments with other methods, as no single treatment can cure cancer alone.

Takeaways

• 😀 Artemisinin, derived from the plant Artemisia annua (wormwood), has been used for its anti-malarial properties but shows potential for treating various health conditions.
• 😀 Artemisinin is now being explored for its possible use in treating cancer, autoimmune diseases, and inflammatory conditions due to its anti-inflammatory effects.
• 😀 Research suggests that Artemisinin may help in treating diseases like systemic lupus erythematosus (SLE), rheumatoid arthritis, and even skin protection and wound healing.
• 😀 Artemisinin shows promise in cancer treatment, with laboratory evidence indicating its ability to reduce tumor growth and metastasis, especially in cancers like leukemia.
• 😀 The compound might also have therapeutic potential in addressing fibrosis (abnormal tissue formation) in organs like the liver, kidneys, and lungs.
• 😀 Studies on mice show that Artemisinin derivatives can help prevent pulmonary fibrosis caused by chemotherapy drugs like bleomycin, offering possible protection for patients undergoing such treatments.
• 😀 While Artemisinin is not a cure-all, it may provide a supportive role in cancer therapy, particularly when combined with traditional treatments like chemotherapy.
• 😀 Artemisinin has poor bioavailability, meaning it is not easily absorbed by the body, leading to the development of derivatives that improve its penetration, including into the brain.
• 😀 There is clinical evidence that Artemisinin derivatives like Artesunate have reduced tumor size and metastases in various cancer types, though the results are not always conclusive.
• 😀 Combining Artemisinin with chemotherapy or other treatments might help counteract tumor resistance, enhance therapeutic outcomes, and improve the quality of life and life expectancy for cancer patients.

Q & A

What is Artemisinin and where does it come from?

Artemisinin is a compound derived from the plant Artemisia annua, commonly known as sweet wormwood. It is primarily known for its anti-malarial properties, used in the treatment of malaria, but it also has potential applications in other health conditions.

How does Artemisinin work against malaria?

Artemisinin works by targeting the malaria parasite in the bloodstream. It disrupts the parasite's ability to metabolize iron, which leads to its destruction, thereby alleviating the symptoms of malaria.

What other potential uses does Artemisinin have beyond malaria treatment?

Artemisinin has been researched for its anti-inflammatory effects, showing promise in treating autoimmune diseases like lupus and rheumatoid arthritis. Additionally, it may be useful for conditions involving fibrosis, such as lung fibrosis and kidney damage due to diabetes.

Can Artemisinin be used in cancer treatment?

Yes, Artemisinin has shown potential as a complementary treatment in oncology. It has been found to help in reducing tumor growth and metastasis, and it might also improve the efficacy of conventional cancer therapies like chemotherapy.

What is the issue with the bioavailability of Artemisinin?

Artemisinin has low bioavailability, meaning it is not easily absorbed or able to penetrate cell membranes. This limits its effectiveness unless modified into more bioavailable derivatives, like Artemisinin-based compounds, which can more effectively target tumors.

What are the potential side effects of Artemisinin-based treatments?

While generally considered safe, high doses of Artemisinin-based treatments can lead to side effects such as hearing loss, dizziness, liver toxicity, and a reduction in white blood cell counts, which can weaken the immune system.

How effective is Artemisinin when used alone in treating cancer?

Artemisinin alone has shown some effectiveness in reducing tumor size in early studies, but it is generally not sufficient for a complete cure. It is often used in combination with other treatments like chemotherapy to address the cancer more comprehensively.

What role does Artemisinin play in cancer cell death mechanisms?

Artemisinin may trigger a form of cell death known as ferroptosis, which is iron-dependent and distinct from traditional apoptosis. This provides a potential new mechanism for targeting cancer cells.

What were the results of studies involving Artemisinin in cancer treatment?

Studies have shown that Artemisinin-based compounds like Artesunate can reduce tumor size, delay metastasis, and in some cases, extend patient survival. However, resistance can develop, and the treatment should ideally be part of a combination therapy.

Can Artemisinin help with fibrosis, and if so, how?

Yes, Artemisinin has potential in treating fibrosis, which involves the formation of excessive connective tissue in organs like the liver, kidneys, and lungs. It has been shown to reduce the development of fibrosis in animal models, possibly helping to prevent organ damage.