Kelompok 6 Teripang Nanas GAG & EPA

Summary

This presentation explores the potential of *Tripang Nanas* (sea cucumber) as a sustainable raw material for pharmaceutical applications. The group highlights its healing properties, such as wound healing, anti-cancer effects, and immune-boosting benefits, driven by bioactive compounds like collagen, Glycosaminoglycans (GAGs), and Eicosapentaenoic Acid (EPA). The presentation also discusses challenges related to processing technology, slow reproduction rates, and high production costs, alongside solutions like sustainable farming, collaborative research, and regulatory frameworks to ensure long-term availability and eco-friendly harvesting.

Takeaways

• 😀 *Teripang Nanas* (cucumber sea cucumber) is a natural raw material with high potential for pharmaceutical use, specifically for wound healing.
• 😀 The bioactive compounds in *teripang nanas* include collagen (80% of its protein content), glycosaminoglycans (GAG), and eicosapentaenoic acid, all contributing to its therapeutic properties.
• 😀 *Teripang nanas* has antimicrobial, anti-inflammatory, and immune-boosting effects due to its high protein content and bioactive compounds.
• 😀 The species is abundant in Indonesian waters, especially around coral reefs, making it a sustainable resource when harvested responsibly.
• 😀 In Indonesia, *teripang nanas* is primarily used for food products like dried and fried sea cucumber, and for medicinal purposes in herbal remedies and cancer treatment.
• 😀 The raw material's potential as a skin care ingredient is also significant, given its collagen content that supports tissue regeneration and skin elasticity.
• 😀 The proposed timeline for development includes literature review, sample collection, laboratory analysis, preclinical and clinical testing, and education for local communities.
• 😀 Sustainability efforts involve responsible harvesting, ecosystem protection, and the development of sustainable management practices to prevent overfishing of *teripang nanas*.
• 😀 Major challenges include technological limitations in processing *teripang nanas*, slow reproduction rates of the species, and high production costs due to the complex processing required.
• 😀 Solutions for these challenges include investments in cultivation technology, research collaborations with academic and industry stakeholders, and stricter regulations to prevent illegal overfishing.

Q & A

What is *teripang nanas* and why was it chosen as a pharmaceutical raw material?

Teripang nanas (*Thelenota ananas*), a species of sea cucumber, was chosen due to its rich content of active compounds like protein (collagen), glycosaminoglycans (GAGs), and eicosapentaenoic acid, which contribute to wound healing, anti-inflammatory, and immune-boosting properties.

What are the key bioactive components found in *teripang nanas*?

The key bioactive components in *teripang nanas* include collagen (a protein), glycosaminoglycans (GAGs), and eicosapentaenoic acid (EPA). These contribute to the therapeutic properties such as wound healing, anti-inflammatory effects, and immune system support.

How does *teripang nanas* contribute to wound healing?

The protein, particularly collagen, found in *teripang nanas* plays a vital role in tissue regeneration and wound healing by aiding in cell repair and the formation of new tissue. GAGs also support skin elasticity, making it effective in healing wounds.

What other therapeutic applications are suggested for *teripang nanas* besides wound healing?

Besides wound healing, *teripang nanas* is also suggested for use in anti-cancer treatments, particularly through the compound frondoside A, as well as for improving joint health, supporting skin care, and boosting the immune system.

Why is *teripang nanas* considered a sustainable resource for the pharmaceutical industry?

The sustainability of *teripang nanas* lies in its abundance in Indonesia’s coral reefs and its potential for responsible harvesting. However, the species' sustainability depends on effective management and conservation efforts to avoid overexploitation.

What challenges are associated with the procurement and processing of *teripang nanas*?

Challenges include the slow reproductive cycle of *teripang nanas*, overharvesting, the need for specialized technology to process it into pharmaceutical-grade products, and the high costs involved in the production and processing stages.

How can *teripang nanas* be sustainably harvested and preserved?

Sustainable harvesting can be achieved through practices like stocking and releasing juvenile *teripang nanas* into suitable environments, responsible fishing techniques that avoid damaging coral reefs, and regulatory measures to monitor overexploitation.

What role do local communities play in the sustainability of *teripang nanas* harvesting?

Local communities, particularly fishermen and coastal farmers, are crucial in ensuring the sustainable harvesting of *teripang nanas*. They are involved in the management, training for responsible harvesting, and educational outreach about the species' importance.

What are the proposed solutions to the challenges faced in *teripang nanas* procurement?

Proposed solutions include investing in technology for sustainable farming and processing, collaborating with academic and research institutions to develop efficient extraction methods, increasing public awareness, and enforcing strict regulations on illegal harvesting.

How can the pharmaceutical industry benefit from *teripang nanas* in terms of product development?

The pharmaceutical industry can benefit from *teripang nanas* by developing a range of products, including wound healing ointments, anti-cancer treatments, immune-boosting supplements, and skincare products. The bioactive compounds found in the sea cucumber offer multiple therapeutic applications.