MDP

Summary

The video outlines the preparation and application of the methylene diphenyl (MDP) kit for diagnosing bone abnormalities using radioactive sodium pertechnetate. It details essential safety protocols, such as wearing sterile gloves and inspecting vials before use. The preparation process involves careful mixing of the lyophilized powder and the sodium solution, with specific instructions for labeling and storage. Important patient considerations are highlighted, including monitoring liver health and adjusting dosages based on weight. The video serves as a comprehensive guide for healthcare professionals, ensuring effective and safe usage of the MDP solution.

Takeaways

• 🧪 The MDP application involves a lyophilized powder of methylene diphenyl and is labeled with radioactive 99mTc sodium pertechnetate for imaging and diagnosing bone abnormalities.
• 🧤 Always wear sterile gloves during the preparation and handling of the MDP kit to ensure safety and contamination prevention.
• 🔍 Before use, check the vials for any signs of damage, such as broken or cracked seals, and do not use any damaged vials.
• 💉 The preparation involves injecting 2 to 5 mL of sterile non-pyrogenic 99mTc sodium pertechnetate solution into the vial kit, adhering to the maximum recommended activity of 300 mCi.
• 🔄 After injecting, shake the vial gently for 30 seconds to ensure complete dissolution of the lyophilized powder and wait 20 minutes for stabilization.
• 👀 Inspect the final solution for clarity; if it appears blurred or discolored, it must not be used.
• 🗓 Record critical information, including the preparation date, time, volume, activity, and preparer's name on the solution label, and attach it to the lead shield.
• 🌡 Store the prepared 99mTc MDP solution at room temperature (15-25°C) and use it within 6 hours after labeling.
• ⚖️ Always measure the activity of the 99mTc MDP solution in a calibrator before administration to ensure accurate dosing.
• 🧑‍⚕️ Consider patient history, particularly conditions like fatty liver disease, and medication interactions that may affect liver uptake when determining the injected activity.

Q & A

What is the primary use of the 99mTc MDP kit?

The 99mTc MDP kit is primarily used for imaging and diagnosing abnormal growth in bones.

What precautions should be taken during the preparation of the MDP solution?

Sterile gloves should be worn, and the vials should be checked for any cracks or damage before use.

How should the rubber stopper of the vial be treated before injection?

The rubber stopper should be cleaned with alcohol swabs to ensure sterility before injecting the sodium pertechnetate solution.

What is the recommended amount of sodium pertechnetate to inject into the vial?

The recommended amount of sodium pertechnetate to inject is between 2 to 5 milliliters.

How long should the vial be shaken to ensure the lyophilized powder is dissolved?

The vial should be shaken inversely for at least 30 seconds.

What should be done if the solution appears cloudy or discolored after preparation?

If the solution is cloudy or discolored, it must not be used and should be discarded.

What are the storage requirements for the prepared 99mTc MDP solution?

The prepared solution should be stored at room temperature (15-25°C) and is usable only within six hours after labeling.

What additional checks should be performed related to patient history before administering the MDP solution?

Patient history should be checked for conditions such as fatty liver and any medications that may affect liver function, like aluminum hydroxide or iron supplements.

What information must be recorded on the solution label after preparation?

The solution label must include the preparation date, time, volume, activity, and the name of the preparer.

What should be done before using the 99mTc MDP solution?

A dose measurement should be made using a calibrator to determine the radioactivity extent before administration.