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21 Dec 202108:04

Summary

TLDRThis educational video delves into protein synthesis and enzymatic activity, focusing on the structure and function of proteins. It explains that proteins are composed of amino acids, with each type having a unique R group. The video introduces bi-dimensional chromatography, a technique for identifying amino acids based on solubility. It also highlights three key characteristics that distinguish proteins: a specific total number of amino acids, a specific number of each amino acid type, and a unique sequence of amino acids. The script concludes with a brief overview of the chemical elements in amino acids and their general chemical formula.

Takeaways

  • 🌟 Protein synthesis and enzymatic activity are the focus of the new chapter, emphasizing the role of amino acids in protein formation.
  • 🔍 The lesson aims to help learners recognize that proteins are composed of amino acids and understand the chemical elements within them.
  • 📚 By the end of the lesson, students should be able to list the chemical elements found in an amino acid and write the chemical formula of an amino acid.
  • 🧬 A summary sheet will be provided to outline the learning objectives, building on previous knowledge about genetic material from chapter 2.
  • 🩸 Examples of proteins in the body include hemoglobin for oxygen transport, antibodies for immune response, and keratin for hair and nail structure.
  • 🧬 There are 20 different types of amino acids, which are the building blocks of proteins, each differing by their R group.
  • 🔬 Bi-dimensional chromatography is a technique used to identify the chemical constituents of a protein by separating amino acids based on their solubility.
  • 🔑 Each amino acid has a central carbon atom (alpha carbon), an amino group, a carboxylic group, and a unique R group or side chain.
  • 📊 Proteins are characterized by a specific total number of amino acids, a specific number of each type of amino acid, and a specific sequence of amino acids.
  • 📝 The chemical formula of an amino acid includes carbon, hydrogen, oxygen, and nitrogen, with a central alpha carbon atom, hydrogen, amino group, carboxylic group, and R group.

Q & A

  • What is the main focus of the chapter on protein synthesis and enzymatic activity?

    -The main focus of the chapter is to understand how proteins are synthesized and the role of enzymatic activity in this process, starting with the association of amino acids.

  • What are the objectives of the lesson on proteins and amino acids?

    -The objectives are to recognize that proteins are made up of amino acids, to list the chemical elements found in an amino acid, and to write the chemical formula of an amino acid.

  • What is the role of hemoglobin in the body?

    -Hemoglobin is a protein found inside blood cells that picks up oxygen molecules and carries them around the body.

  • How do antibodies function in the immune system?

    -Antibodies are proteins dispatched by immune cells to attack foreign invaders.

  • What is the structural protein found in hair and nails?

    -The structural protein found in hair and nails is keratin.

  • How many different types of amino acids are there, and what are they the building blocks of?

    -There are 20 different types of amino acids, and they are the building blocks of proteins.

  • What technique is used to identify the chemical constituents of a protein?

    -Bi-dimensional chromatography is the technique used to identify the chemical constituents of a protein by allowing the migration of amino acids based on their degree of solubility in a given solvent.

  • What are the common features of all amino acids?

    -All amino acids have a central carbon atom (alpha carbon), an amino group, a carboxylic group, and a hydrogen atom.

  • What is the significance of the R group in amino acids?

    -The R group, or side chain, is what differentiates one amino acid from another and determines the identity of the amino acid.

  • What are the three characteristics that define each protein molecule?

    -Each protein molecule is characterized by a specific total number of amino acids, a specific number of each type of amino acid, and a specific sequence of amino acids.

  • What are the chemical elements that make up an amino acid?

    -Amino acids are made up of carbon, hydrogen, oxygen, and nitrogen.

  • What is the general chemical formula of an amino acid?

    -The general chemical formula of an amino acid includes a central carbon atom (alpha carbon), hydrogen, an amino group, a carboxylic group, and an R group.

Outlines

00:00

🧬 Protein Synthesis and Amino Acids

This paragraph introduces the concept of protein synthesis and enzymatic activity, focusing on the structure of proteins and their constituent amino acids. It explains that proteins are made up of amino acids and highlights the importance of recognizing the chemical elements found in amino acids and their chemical formulas. The paragraph also reviews the role of genetic material in protein production and provides examples of proteins found in the body, such as hemoglobin, antibodies, and keratin. It introduces bi-dimensional chromatography as a technique for identifying the chemical constituents of proteins based on the solubility of amino acids. The paragraph concludes with an overview of the 20 different types of amino acids, emphasizing their common structure and the unique R group that distinguishes each one.

05:01

🔍 Characteristics of Protein Molecules

This paragraph delves into the specific characteristics that define protein molecules. It discusses how each protein has a unique total number of amino acids, a specific number of each type of amino acid, and a specific sequence of amino acids. The paragraph uses examples from a table comparing the amino acid composition of different proteins, such as pro-insulin, insulin, gastrin, and casein, to illustrate these points. It also contrasts normal and abnormal insulin to highlight the importance of the specific sequence of amino acids. The summary emphasizes the chemical composition of amino acids, which includes carbon, hydrogen, oxygen, and nitrogen, and describes the general chemical formula of an amino acid, including the alpha carbon, hydrogen, amino group, carboxylic group, and the R group that defines each amino acid's identity.

Mindmap

Keywords

💡Protein Synthesis

Protein synthesis refers to the biological process by which cells build proteins, which are essential for the structure, function, and regulation of the body's tissues and organs. In the video, this concept is central as it sets the stage for understanding how amino acids come together to form complex proteins that are vital for various bodily functions.

💡Enzymatic Activity

Enzymatic activity is the function of enzymes, which are proteins that catalyze chemical reactions in the body. The video touches on this by discussing how enzymes might be involved in the processes related to protein synthesis, although the main focus is on the synthesis itself rather than the enzymes' roles.

💡Amino Acids

Amino acids are the building blocks of proteins, consisting of an amino group, a carboxyl group, a hydrogen atom, and a side chain that varies among different amino acids. The video emphasizes that proteins are made up of these units, highlighting the diversity and specificity of amino acids in protein structure.

💡Central Carbon Atom

The central carbon atom, also known as the alpha carbon, is a key component of amino acids. Each amino acid has one, and it is the point where the amino group, carboxyl group, hydrogen, and the side chain (R group) are attached. The video uses this term to describe the common structure of all amino acids.

💡R Group

The R group, or side chain, is the variable part of an amino acid that determines its specific properties. The video explains that amino acids differ from each other primarily by their R groups, which is crucial for understanding how the same basic building blocks can form a vast array of proteins with different functions.

💡Bi-dimensional Chromatography

Bi-dimensional chromatography is a technique used to separate and identify the chemical constituents of a protein, such as amino acids, based on their solubility in a given solvent. The video mentions this technique as a method to analyze the composition of proteins, although it is not the main focus of the lesson.

💡Hemoglobin

Hemoglobin is a protein found in red blood cells that is responsible for carrying oxygen throughout the body. The video uses hemoglobin as an example of a protein with a specific function, illustrating the diversity of proteins and their roles in the body.

💡Antibodies

Antibodies are proteins produced by the immune system to identify and neutralize foreign objects like bacteria and viruses. The video mentions antibodies as an example of proteins with a protective role in the body, highlighting the immune system's use of proteins.

💡Keratin

Keratin is a structural protein found in hair, nails, and the outer layer of the skin. The video includes keratin as an example of a protein that provides structural support, showing how proteins contribute to the body's physical form.

💡Chemical Formula of Amino Acids

The chemical formula of an amino acid is represented in the video as a central carbon atom with attached hydrogen, an amino group, a carboxylic group, and an R group. This formula is essential for understanding the basic structure of amino acids and, by extension, the proteins they form.

💡Characteristics of Protein Molecules

The video outlines three characteristics of protein molecules: a specific total number of amino acids, a specific number of each type of amino acid, and a specific sequence of amino acids. These characteristics are crucial for understanding how proteins are uniquely structured and function in the body.

Highlights

Introduction to the chapter on protein synthesis and enzymatic activity.

Objective to recognize that proteins are made up of amino acids and to list the chemical elements found in an amino acid.

Overview of the genetic material's role in protein production.

Recall of proteins found in the body, such as hemoglobin, antibodies, and keratin.

Explanation of the diversity and functions of proteins in the body.

Introduction to amino acids as the building blocks of proteins, with 20 different types.

Description of bi-dimensional chromatography as a technique to identify amino acids in proteins.

Examples of different amino acids: alanine, methionine, and phenylalanine.

Explanation of the structure of amino acids, including the alpha carbon, amino group, carboxylic group, and R group.

Introduction to the 20 different types of amino acids and their role in protein structure.

Discussion on the characteristics that differentiate proteins: total number, types, and sequence of amino acids.

Example of how pro-insulin and insulin differ in their amino acid composition.

Emphasis on the importance of the specific sequence of amino acids in protein structure.

Summary of the three characteristics of a protein molecule: specific number of amino acids, specific number of each type, and specific sequence.

Chemical composition of an amino acid, including carbon, hydrogen, oxygen, and nitrogen.

Chemical formula of an amino acid, highlighting the alpha carbon, hydrogen, amino group, carboxylic group, and R group.

Conclusion of the lesson with a recap of the key points about proteins and amino acids.

Transcripts

play00:00

[Music]

play00:11

today we will start with a new chapter

play00:13

protein synthesis and enzymatic activity

play00:16

we will start with activity 1 proteins

play00:19

and association of amino acids

play00:22

at the end of this lesson

play00:24

we will be able to recognize that each

play00:26

protein is made up of amino acids list

play00:29

the chemical elements found in an amino

play00:31

acid and write the chemical formula of

play00:33

an amino acid

play00:36

we will be supplied with a summary sheet

play00:38

concerning the required objectives

play00:41

previously in chapter 2 we have

play00:43

discussed some facts about the genetic

play00:45

material that is found in the cell

play00:47

but if you remember this genetic

play00:49

material is basis of all proteins that

play00:51

are produced

play00:53

in this chapter we will study about

play00:55

protein synthesis and enzymatic activity

play00:59

first of all

play01:00

can you recall back where proteins are

play01:02

found in the body

play01:04

let's recall back together some examples

play01:06

of proteins

play01:16

some proteins you may have heard of

play01:19

the hemoglobin found inside our blood

play01:21

cells is a protein

play01:23

its job is to pick up oxygen molecules

play01:26

and carry them around our body

play01:28

[Music]

play01:34

antibodies are proteins

play01:39

they're dispatched by our immune cells

play01:41

to attack foreign invaders

play01:46

and hair and nails get their structure

play01:48

from keratin that's a protein too

play01:53

[Music]

play01:55

there are literally thousands of weird

play01:58

and wonderful types of protein

play02:00

frantically busy carrying out all the

play02:02

activities that make cells alive

play02:09

as known the building blocks or

play02:10

constituents of proteins are amino acids

play02:13

and there are 20 different types of

play02:15

amino acids

play02:17

but how can we identify the amino acids

play02:20

that constitute a specific protein

play02:22

molecule

play02:24

there is a technique that allows to

play02:25

identify the chemical constituents of a

play02:28

protein

play02:30

this technique allows the migration of

play02:33

the amino acids

play02:36

according to their degree of solubility

play02:39

in a given solvent

play02:42

so again

play02:43

this technique allows the migration of

play02:45

amino acids depending on their degree of

play02:48

solubility in a given solvent

play02:52

this technique is called bi-dimensional

play02:55

chromatography

play02:59

let's have some examples of different

play03:00

amino acids

play03:03

alanine methionine and phenylalanine

play03:06

these three different amino acids

play03:09

have

play03:10

a central carbon atom

play03:12

in the middle

play03:14

they have

play03:16

the carboxylic group

play03:19

the amino group

play03:20

and a hydrogen atom

play03:23

in common however

play03:25

they differ

play03:27

by

play03:28

a group that is described as

play03:30

r group so amino acids differ from each

play03:34

other by their r groups

play03:36

so every amino acid has

play03:40

a central carbon atom

play03:42

termed as alpha carbon

play03:45

an amino group

play03:48

carboxylic group

play03:50

and an organic r group or the side chain

play03:54

that determines the identity of the

play03:56

amino acid

play03:58

here we can see the 20 different types

play04:00

of amino acids

play04:02

alanine glycine isolecine lucian proline

play04:07

valine

play04:08

phenylalanine tryptophan tyrosine

play04:11

aspartic acid glutamic acid

play04:14

arginine histidine

play04:17

lysine serine threonine

play04:20

cysteine methionine asparagine and

play04:23

glutamine

play04:25

of course here we just have to be

play04:27

familiar with these amino acids and we

play04:29

aren't responsible

play04:31

to study their names

play04:34

although proteins constitute from the

play04:36

same building blocks

play04:38

they differ from each other so what

play04:40

characterizes each protein molecule

play04:44

here we have a table

play04:45

that shows the different constitutions

play04:47

of amino acids

play04:49

among four different proteins the

play04:51

pro-insulin insulin gastrin and

play04:54

casein after observing the table and

play04:58

observing the total numbers we notice

play05:00

that each protein has a different total

play05:04

number of amino acids

play05:06

this helps us to conclude the first

play05:08

characteristic concerning

play05:10

the difference among proteins which is

play05:13

that each protein has a specific total

play05:16

number of amino acids

play05:19

if we refer to the same table again we

play05:21

noticed that different types of proteins

play05:24

may constitute the same types of amino

play05:26

acids but with different numbers

play05:28

like for example the first two amino

play05:30

acids if we take the first two proteins

play05:33

the pro insulin and insulin we notice

play05:36

that they both constitute of alanine

play05:39

where pro-insulin constitutes of four

play05:42

more than insulin does which constitutes

play05:44

of only one allen molecule

play05:47

also they both constitute of glutamine

play05:50

where pro-insulin has seven glutamine

play05:53

molecules

play05:54

where insulin has only three

play05:57

they also constitute overglycin but

play06:00

pro-insulin contains eighty glycine

play06:02

molecules more than insulin does which

play06:05

contains only four

play06:07

then we come up with the second

play06:08

characteristic which is that each

play06:11

protein has a specific number of each

play06:14

type of amino acids

play06:16

now concerning the last characteristic

play06:18

here we can take an example

play06:21

two segments of proteins

play06:24

one

play06:25

corresponding to normal insulin and the

play06:27

other for abnormal insulin

play06:30

we noticed that

play06:31

they they both have the same

play06:34

constitution of amino acids except for

play06:37

one amino acid which is here histidine

play06:41

in the normal insulin chain

play06:43

which is replaced by aspartic acid in

play06:46

the abnormal insulin

play06:49

here we can conclude the last

play06:52

characteristic which is

play06:54

that each protein has a specific

play06:56

sequence of amino acids

play06:59

now let's sum up the characteristics of

play07:01

a protein molecule

play07:03

first each protein molecule has a

play07:06

specific number of amino acids

play07:08

it has a specific number of each type of

play07:11

amino acid

play07:13

and finally it has a specific sequence

play07:16

of amino acids

play07:18

to sum up each protein is made up of

play07:20

amino acids each protein is

play07:22

characterized by

play07:24

having a specific number of amino acids

play07:27

by an specific number of each type of

play07:29

amino acids and a specific sequence of

play07:32

amino acids an amino acid is made up of

play07:35

the chemical elements carbon hydrogen

play07:37

oxygen and nitrogen

play07:39

and the chemical formula of an amino

play07:41

acid is as follows

play07:43

a central carbon atom termed as alpha

play07:46

carbon

play07:47

hydrogen

play07:49

amino group

play07:50

carboxylic group and the r group which

play07:53

is specific for every amino acid

play07:56

thanks for listening

play08:00

[Music]

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Related Tags
Protein SynthesisAmino AcidsEnzymatic ActivityBi-dimensional ChromatographyHemoglobinAntibodiesKeratinAlpha CarbonCentral CarbonChemical Elements