Anatomy of the Endocrine System

UC Anatomy and Physiology
19 Jul 202323:10

Summary

TLDRThis script delves into the endocrine system, highlighting its role alongside the nervous system in maintaining homeostasis. It explains how endocrine glands release hormones into the bloodstream to target specific cells, influencing functions such as energy storage, growth, and stress response. The video distinguishes between exocrine and endocrine glands, emphasizing the latter's ductless secretion method, and introduces the 10 major endocrine glands, setting the stage for further exploration of their hormonal roles.

Takeaways

  • 😀 The endocrine system works alongside the nervous system to maintain homeostasis in the body.
  • 🚀 The endocrine system exerts its influence more slowly than the nervous system, through the release of hormones into the blood.
  • 🌟 Endocrine glands produce hormones that target specific cells and have various effects throughout the body.
  • 🔍 The process of hormone action involves secretion into interstitial fluid, diffusion into capillaries, and binding to specific receptors on target cells.
  • 🔄 Hormone-receptor binding can lead to changes in target cells, such as altering cell membrane permeability, enzyme activation, or stimulating mitosis.
  • 🌱 Hormones play a crucial role in energy storage and utilization, as exemplified by insulin and glucagon's regulation of blood glucose levels.
  • 👶 Hormones are essential for growth, puberty, maturation, and development of sex cells, as well as pregnancy and birth.
  • 🛡 The body's response to stress, such as the fight or flight response, is controlled by hormones like adrenaline.
  • 🔄 Receptors for hormones can be upregulated or downregulated depending on the hormone concentration, affecting the cell's sensitivity to the hormone.
  • ⚖️ The endocrine and exocrine glands differ in their secretion methods, with endocrine glands releasing hormones directly into the bloodstream and exocrine glands secreting into ducts or body cavities.
  • 📍 The major endocrine glands include the pituitary, pineal, thyroid, parathyroid, adrenal glands, pancreas, ovaries (in females), and testes (in males).

Q & A

  • What is the primary role of the endocrine system in the body?

    -The primary role of the endocrine system is to help maintain homeostasis, along with the nervous system, by releasing hormones into the bloodstream that target specific cells and have various effects.

  • How does the endocrine system differ from the nervous system in terms of its response speed?

    -The endocrine system acts more slowly compared to the nervous system. While the nervous system acts quickly through electrical impulses or action potentials, the endocrine system exerts its effects through the gradual release of hormones into the blood.

  • What are hormones and how do they function within the body?

    -Hormones are chemicals released into the blood by endocrine glands. They travel through the bloodstream, bind to receptors on target cells, and cause a specific cellular response, thus having their effect.

  • Can you explain the process of how a hormone is released and travels to its target cell?

    -An endocrine gland secretes a hormone into the interstitial fluid, which then diffuses into a capillary. The hormone travels through the bloodstream until it reaches a target cell with a specific receptor. The hormone binds to this receptor, causing a change in the target cell that allows the hormone to exert its effect.

  • What is the concept of down regulation in the context of hormone-receptor interactions?

    -Down regulation refers to the decrease in the number of receptors on a target cell when there is an excess of a particular hormone. This makes the target cell less sensitive to the hormone, preventing it from having too strong of an effect.

  • What is the opposite process of down regulation called, and what does it involve?

    -The opposite of down regulation is called up regulation, which involves an increase in the number of receptors on a target cell when there is a deficiency of a particular hormone. This makes the target cell more sensitive to the hormone.

  • How does the hormone adenosine affect our daily energy levels and sleep patterns?

    -Adenosine is a hormone that builds up as we exert energy throughout the day. When it binds to its receptors, it makes us feel tired and sleepy. The loss of adenosine by the end of the day is thought to trigger the need for sleep.

  • What is the relationship between caffeine and adenosine receptors, and how does this affect our alertness?

    -Caffeine, structurally similar to adenosine, can bind to adenosine receptors, preventing adenosine from binding and causing its fatigue-inducing effect. This is why caffeine can make us feel more alert and awake.

  • How do hormones influence the storage and utilization of energy in the body?

    -Hormones, such as insulin and glucagon released from the pancreas, play a significant role in energy storage and utilization. Insulin facilitates the storage of glucose as glycogen, while glucagon triggers the breakdown of glycogen to release glucose back into the blood for energy.

  • What are the main functions of the endocrine system in maintaining homeostasis?

    -The endocrine system helps maintain homeostasis by influencing energy storage and utilization, regulating growth and reproduction, and controlling body responses to external stimuli, such as the stress response.

  • Can you describe the difference between exocrine and endocrine glands in terms of their secretion methods?

    -Exocrine glands secrete their products into ducts that lead to body cavities or the outer surface of the body. In contrast, endocrine glands secrete hormones directly into the interstitial fluid, from where they diffuse into the bloodstream and are carried to target cells throughout the body.

  • What are the 10 major endocrine glands mentioned in the script, and what is unique about the pancreas among them?

    -The 10 major endocrine glands are the pituitary gland (anterior and posterior), pineal gland, thyroid gland, parathyroid glands, adrenal glands, pancreas, ovaries (in females), and testes (in males). The pancreas is unique because it has both exocrine and endocrine functions, releasing hormones like insulin and glucagon for its endocrine role, and digestive enzymes for its exocrine role.

Outlines

00:00

🌟 Endocrine System Overview and Function

The first paragraph introduces the endocrine system, highlighting its role alongside the nervous system in maintaining homeostasis. It explains that the endocrine system operates more slowly by releasing hormones into the bloodstream. The paragraph also clarifies the distinction between exocrine and endocrine glands, emphasizing that endocrine glands produce hormones that target specific cells. The learning objectives include understanding the anatomy of the endocrine system, describing its function, and identifying the 10 major endocrine glands. Hormones are described as chemical messengers that bind to receptors on target cells to elicit specific responses.

05:02

🔍 Hormone Mechanism and Receptor Dynamics

This paragraph delves into the process of hormone release and action. It details how hormones are secreted by endocrine glands into the interstitial fluid and then into the bloodstream, where they travel to target cells with specific receptors. The concept of receptor specificity is introduced, explaining how hormones can only affect cells with the appropriate receptors. The paragraph also discusses the regulatory mechanisms of receptor numbers, including down regulation to reduce sensitivity when hormone levels are high and up regulation to increase sensitivity when hormone levels are low, using examples such as adenosine and caffeine to illustrate these processes.

10:02

🏋️‍♂️ Hormonal Influences on Energy, Growth, and Stress Response

The third paragraph discusses the various functions of the endocrine system, focusing on its role in energy storage and utilization, growth and reproduction regulation, and the body's response to external stimuli. It provides examples such as insulin and glucagon's role in blood glucose management, and the influence of hormones on puberty, sex cell development, and pregnancy. The paragraph also touches on the stress response, explaining the fight or flight mechanism triggered by adrenaline, which prepares the body for stressful situations by increasing heart rate and blood flow, and facilitating glycogen breakdown for energy supply.

15:04

🔬 Effects of Hormones on Target Cells

This paragraph explores the specific effects hormones have on target cells once they bind to their receptors. It outlines several mechanisms, including changes in cell membrane permeability, activation or deactivation of enzymes, alterations in secretory activity, and stimulation of mitosis. Each mechanism is exemplified, such as the anti-diuretic hormone's effect on water reabsorption in the kidneys and the role of growth hormone in stimulating cell division for growth.

20:05

📚 Identification of Major Endocrine Glands

The final paragraph provides an overview of the major endocrine glands, distinguishing between those that are specific glands and those that are tissues within other organs. It describes the pituitary gland, pineal gland, thyroid gland, parathyroid glands, adrenal glands, pancreas, ovaries, and testes, detailing their locations and noting the dual exocrine and endocrine functions of the pancreas. The paragraph sets the stage for further discussion on the hormones released by these glands and their effects in subsequent lectures.

Mindmap

Keywords

💡Endocrine System

The endocrine system is a collection of glands and tissues that produce hormones to regulate various bodily functions. It plays a critical role in maintaining homeostasis alongside the nervous system. In the script, it is described as acting more slowly than the nervous system, exerting its effects through the release of hormones into the bloodstream rather than through electrical impulses.

💡Hormones

Hormones are chemical messengers released into the bloodstream by the endocrine glands. Each hormone targets specific cells and has unique effects. The script explains how hormones are secreted, travel through the blood, and bind to receptors on target cells to elicit a response, exemplified by the processes of insulin and glucagon release from the pancreas.

💡Homeostasis

Homeostasis refers to the body's ability to maintain a stable internal environment despite external changes. The endocrine system, along with the nervous system, helps to achieve this by regulating various physiological processes. The script mentions that the endocrine system's role in homeostasis includes influencing energy storage and utilization, growth and reproduction, and responses to external stimuli.

💡Exocrine Glands

Exocrine glands are glands that secrete their products into ducts leading to body cavities or the outer surface. They are contrasted with endocrine glands in the script, with examples provided such as sweat glands, oil glands, and digestive glands, which are not part of the endocrine system.

💡Endocrine Glands

Endocrine glands are ductless and secrete hormones directly into the interstitial fluid, from where they diffuse into the bloodstream. The script distinguishes these from exocrine glands and lists several major endocrine glands, including the pituitary, thyroid, adrenal glands, and the pancreas, among others.

💡Pituitary Gland

The pituitary gland, often referred to as the 'master gland,' is an endocrine gland located beneath the hypothalamus. It is divided into the anterior and posterior pituitary, each releasing different hormones. The script describes its anatomical location and its role in releasing various hormones that regulate other endocrine glands.

💡Pineal Gland

The pineal gland is an endocrine gland that has connections with the visual system and is located near the occipital lobe of the brain. It is known for producing the hormone melatonin, which regulates sleep-wake cycles. The script mentions its location and its ties to the visual system.

💡Thyroid Gland

The thyroid gland is an endocrine gland situated in the front of the neck that produces hormones regulating metabolism. The script describes its location and function, including the release of thyroid hormones in response to Thyroid Stimulating Hormone (TSH) from the pituitary gland.

💡Adrenal Glands

The adrenal glands are endocrine glands located on top of each kidney. They are composed of the adrenal cortex and adrenal medulla, each with distinct functions and hormone production. The script explains their anatomical position and the dual nature of their structure.

💡Parathyroid Glands

The parathyroid glands are four small endocrine glands located on the posterior surface of the thyroid gland. They produce parathyroid hormone, which regulates calcium levels in the blood. The script identifies their location and function in calcium homeostasis.

💡Pancreas

The pancreas is a dual-function gland with both exocrine and endocrine roles. As part of the endocrine system, it produces hormones like insulin and glucagon, which regulate blood sugar levels. The script highlights its unique role in both digestion and hormone production.

💡Ovaries and Testes

The ovaries and testes are the primary reproductive endocrine glands in females and males, respectively. They produce sex hormones, such as estrogen and progesterone in females, and testosterone in males. The script mentions their role in producing sex hormones and their location in the body.

Highlights

The endocrine system, alongside the nervous system, plays a crucial role in maintaining homeostasis through the release of hormones.

The endocrine system exerts its effects more slowly than the nervous system by releasing hormones into the bloodstream.

Endocrine glands produce and release hormones that target specific cells and have various effects throughout the body.

Hormones are chemical messengers that bind to receptors on target cells, causing a specific cellular response.

The process of hormone release and action involves diffusion from interstitial fluid into capillaries and then binding to target cell receptors.

Receptor specificity is crucial for hormones to have an effect, with each hormone fitting its specific receptor like a lock and key.

Hormone-receptor binding can lead to various cellular responses, including changes in membrane permeability and protein synthesis.

Receptor numbers can fluctuate through processes like down regulation, reducing sensitivity when hormone levels are high, and up regulation, increasing sensitivity when hormone levels are low.

Adenosine and caffeine illustrate the dynamic interaction between hormones and their receptors, affecting alertness and sleepiness.

The endocrine system is integral in energy storage and utilization, exemplified by insulin and glucagon's roles in blood glucose regulation.

Hormones significantly influence growth, reproduction, and development, including puberty, maturation of sex cells, and pregnancy.

The body's response to stress is controlled by hormones like adrenaline, preparing the body for fight or flight.

Exocrine and endocrine glands are distinguished by their secretion methods, with exocrine glands using ducts and endocrine glands secreting directly into interstitial fluid.

Major endocrine glands include the pituitary, pineal, thyroid, parathyroid, adrenal, pancreas, ovaries, and testes, each with specific hormonal functions.

The pituitary gland is composed of the anterior and posterior regions, each releasing different hormones with distinct functions.

The adrenal glands have two distinct regions, the adrenal cortex and medulla, each with unique hormonal secretions.

The pancreas has both exocrine and endocrine functions, releasing insulin and glucagon for blood glucose regulation.

The ovaries and testes produce sex hormones essential for sexual development and reproduction.

Transcripts

play00:06

foreign

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beyond the basics and the first organ

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system that we're going to cover in

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systemic anatomy and physiology is the

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endocrine system

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so along with the nervous system the

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endocrine system plays a role in almost

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all of our body's functions by helping

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to maintain homeostasis

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however where the nervous system acts

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quite quickly through electrical

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impulses or action potentials the

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endocrine system exerts its effects more

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slowly by releasing hormones into the

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blood

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as you can see depicted in this image

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here the endocrine system is made up of

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organs or tissues called glands

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and it is these glands that produce and

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release hormones

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hormones are chemicals that are released

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into the blood and would each Target a

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different cell

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and have different effects

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so we have three learning objectives to

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look at the anatomy of the endocrine

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system to First describe the function of

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the endocrine system and briefly how

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endocrine glands and hormones work

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to distinguish between exocrine and

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endocrine glands

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and then to Simply identify the 10 major

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endocrine glands that we're going to

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focus on in this unit

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so starting a learning objective number

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one to describe the function of the

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endocrine system

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so as I briefly mentioned the endocrine

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system is made up of a collection of

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endocrine glands or endocrine tissues

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which are scattered throughout the body

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endocrine glands secrete hormones into

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the bloodstream

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hormones travel through the bloodstream

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and bind to receptors on target cells

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and it is this binding of a hormone to a

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receptor that causes a cell to respond

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in a specific way

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and for the hormone to have its effect

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so taking a look at that process a

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little more closely and we have our

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endocrine gland or our secreting cell in

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yellow here

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and these green circles are our hormone

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so our endocrine glands will either just

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secrete or produce and secrete our

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hormones

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they secrete those hormones into the

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interstitial fluid which surrounds our

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endocrine gland

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from the interstitial fluid that hormone

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will then diffuse into a capillary which

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surrounds all of our endocrine glands

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and that hormone can now travel

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throughout the body in the bloodstream

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that hormone will travel throughout the

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body until it reaches a Target cell so

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we have a Target cell here and a Target

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cell here

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and what makes a cell a Target cell is

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that it has a receptor that is specific

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to that particular hormone

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so see how this round hormone can fit

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into this round part of the receptor

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here perfectly that's because these

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receptors and hormones are specific to

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one another

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if a cell does not have a receptor for a

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particular hormone that hormone cannot

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have an effect on that cell

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so our hormones are released from our

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endocrine glands they travel through the

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interstitial fluid into our capillary

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they travel around the body in the

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bloodstream they then diffuse out of the

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capillary into the interstitial fluid

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they will bind to a receptor on a Target

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cell that is specific to that hormone

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and that binding to a receptor is what

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causes some change in this target cell

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that allows that hormone to have as an

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effect

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now in this example we have receptors

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that sit on the surface of the plasma

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membrane

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we can also have receptors that sit

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within the cell just underneath that

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plasma membrane

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now I just wanted to give you one

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example of a couple of different things

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that can happen to our receptors within

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the body I haven't got a lot of words on

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this slide because this is not something

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that I will test you on but I just want

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you to be aware of this process so like

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any of the other proteins in a cell

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receptors are constantly being produced

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or broken down

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so generally a Target cell will have

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between two and ten thousand receptors

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for a particular hormone but this can

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change at any moment in time

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so for example if we have a lot of a

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particular hormone

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the number of receptors on a Target cell

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May decrease

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this effect is called down regulation

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and it makes a Target cell less

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sensitive to a hormone so we've got too

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much of a particular hormone we don't

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want that hormone to have such a big

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effect so we down regulate the number of

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receptors so that cell is less sensitive

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one example of this is when certain

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cells of the testes are exposed to a

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high concentration of luteinizing

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hormone we will then down regulate the

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number of luteinizing hormone receptors

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that those cells contain

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in contrast when a hormone is deficient

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so there's not much of that hormone in

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circulation we can actually increase the

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number of receptors so this process is

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known as up regulation

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and it makes a Target cell more

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sensitive to a particular hormone

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now this specific example that I've got

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on a slide here is one that I think most

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of us will be somewhat familiar with so

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in the green we have a hormone called

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adenosine

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and adenosine is a hormone or also acts

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as a neurotransmitter which we release

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throughout the day as we exert energy so

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we kind of wake up in the morning and we

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don't have much adenosine as we go about

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our day and we exert energy more and

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more adenosine is circulating throughout

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the human body what adenosine does when

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it binds to its receptors is it makes us

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feel tired and sleepy so the thinking is

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that loss of adenosine by the end of the

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day is what actually makes us want to go

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to bed

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now we also have this molecule called

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caffeine which I'm sure most of us will

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be aware of

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and caffeine in structure is very very

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similar to what our hormone adenosine

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looks like

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what this means is that our caffeine

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molecule can actually bind to our

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adenosine receptor

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and when it's binding to our adenosine

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receptor adenosine can no longer longer

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bind to its own receptor and have its

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fatiguing effect

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so that's why when we have caffeine if

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you have a coffee in the afternoon it

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can kind of wake you up because that

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adenosine can no longer bind to its

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receptor and have that fatiguing or that

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sleepiness kind of effect or feeling

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what happens though when we have a lot

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of caffeine is that there's lots of

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caffeine or lots of caffeine molecules

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circulating throughout the body so our

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brain decides to upregulate the number

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of adenosine receptors so now we have

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lots of adenosine receptors so more

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adenosine confined to those receptors so

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we feel more and more sleepy and now we

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need more and more caffeine to actually

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bind to The receptors so adenosine can't

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bind to its own receptors and have that

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alerting or that energizing effect

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so I just kind of want to point out that

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we have our receptors but that number of

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receptors isn't consistent it can

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actually fluctuate depending on the

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concentration of that hormone within the

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blood as well as the concentration of

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other hormones or molecules present uh

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present within our circulation

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so now that we have I guess a general

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understanding of how hormones work so

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they're released from our endocrine

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glands they then travel throughout the

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blood to our Target cell they need to

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bind to a receptor to then have their

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effect we need to talk about the

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functions of the endocrine system and

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the I guess the effects that the

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hormones have

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so first and foremost the endocrine

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systems role is to help maintain

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homeostasis along with the nervous

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system so all of these points underneath

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maintain homeostasis are simply examples

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of how we actually do that

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so the first example or function that

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we've got here is that hormones can

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influence the storage and utilization of

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energy

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so the best example of that is the

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release of insulin and glucagon from the

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pancreas

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so let's say we have a big lunge

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our blood glucose levels increase

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the pancreas will then release insulin

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which causes the glucose to be taken out

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of the blood and stored as glycogen in

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the liver in our muscles

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and now we have a lower blood glucose

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concentration if the opposite occurs so

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lunch was a number of hours ago and our

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blood glucose concentration is now going

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down our pancreas will release glucagon

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which causes the breakdown of glycogen

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from our liver and our muscles which

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then gets released back into the blood

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so we have an increase in our blood

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glucose concentration and we can use

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those that glucose as energy so our

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hormones play a really big role in the

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storage and the utilization of our

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energy

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hormones can also affect the regulation

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of growth and reproduction

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so both in the next lecture and when we

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get to the reproductive system we're

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going to talk about a whole range of

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hormones that can influence growth

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puberty maturation development of our

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sex cells so eggs and sperm as well as

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pregnancy and birth and all of these

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processes are driven by hormones

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our last example is the control of body

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responses to external stimuli and a

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really nice example of this is stress

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so you may have heard of the fight or

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flight response this is an activation of

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the sympathetic nervous system and it

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occurs when our body encounters a

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stressful situation now our body

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considers stress something like

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exercising but it can also consider you

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know an emergency situation as something

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stressful now what happens in these

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situations is that our body releases the

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hormone adrenaline

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and this helps us prepare for that

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stressful or that emergency situation so

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for example our heart might start

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beating faster

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we might have increased blood flow to

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our working muscles

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we might also have breakdown of glycogen

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in the liver so that we have a big

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supply of glucose in the blood that we

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can use as energy

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so that those flight and sorry fight or

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flight responses are often controlled by

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different hormones

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now

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the way that the endocrine system can

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impart all of those functions that we

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talked about on the previous slide is

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down to the effect that the hormone has

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on their target cells so we kind of

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looked at brief or more General

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functions of the endocrine system but

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exactly how do those hormones affect the

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target cells which allow for those

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effects or allow for those functions so

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again there's a whole range of examples

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and I've just listed five here but one

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example is that when a hormone binds to

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its receptor it can change the cell

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membrane permeability so how easily

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things can pass through that cell

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membrane

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an example of that is anti-diuretic

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hormone so when that hormone binds to

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the tubules in the kidneys it allows

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water to more easily pass through the

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cell membrane so that we can reabsorb

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more water and put it back in the blood

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we can also have the production or the

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synthesis of protein or other regulatory

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molecules when a hormone binds to its

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Target cell

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so for example when thyroid stimulating

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hormone binds to The receptors on the

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thyroid gland it stimulates the

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production of our thyroid hormones which

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are T3 and T4 and we'll talk about these

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more in the next lecture

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The Binding of a hormone can also cause

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activation or deactivation of an enzyme

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so when most of our peptide hormones

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bind to The receptors they activate

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second messages within the cell which

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then activate or deactivate enzymes

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within that cell

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The Binding of a hormone can also alter

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their secretory activity of a cell so

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for example the hormone gastrin can

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stimulate the secretion of gastric acid

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or stomach juices by the parietal cells

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in the stomach

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and lastly The Binding of a hormone to

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its receptor can also stimulate mitosis

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or cell division

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a nice example of that is growth hormone

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which has lots of target cells in all of

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our tissues so our tissues our organs

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our bones our muscles

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and when that hormone binds to the

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receptor it stimulates cell division

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which then obviously results in growth

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so moving on from the functions and the

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effects that our hormones have on a cell

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when they bind to their receptors and

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learning objective number two is to

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distinguish between exocrine glands and

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endocrine glands

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So within the human body we have two

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types of glands we have exocrine glands

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and we have endocrine glands

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exocrine glands with EXO meaning outside

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and cream or crime meaning to secrete

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secrete their products into ducts

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and they carry those secretions into

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body cavities

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into the Lumen of organs which is just

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like the inside of an organ or to the

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body's outer surface

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so for exocrine glands think about your

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sweat glands your oil glands your mucous

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glands and your digestive glands

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for our endocrine glands so with Endo

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meaning within and crying or crin again

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to meaning to secrete

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these uh

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types of glands secrete their products

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which are hormones into the interstitial

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fluid surrounding the endocrine gland

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instead of secreting them into ducts so

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endocrine glands don't have any ducts

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from the interstitial fluid those

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hormones diffuse into the blood in the

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capillaries and the blood carries them

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to the target cells throughout the body

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now because of their dependence on the

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cardiovascular system or the blood to

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distribute their products our endocrine

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glands are some of the most vascular

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tissue in the whole body

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now some of the endocrine glands which

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you may have heard about before and that

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we'll talk about in this lecture are the

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pituitary glands

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our thyroid gland our adrenal and our

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pineal glands

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we also have

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endocrine tissues which are not

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exclusively classified as endocrine

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glands but contain cells that will

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actually secrete hormones so together

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with our specific endocrine glands these

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do make up our endocrine system and so

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these are tissues such as the

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hypothalamus

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the pancreas the ovaries and testes the

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kidneys the stomach the liver and the

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small intestine

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so to give you a bit of a visual and a

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bit of a recap we have our exocrine

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glands on the left and our endocrine

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glands on the right remember our

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exocrine glands have ducts which is just

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this little bit here which then

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transfer the secretions to wherever

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they're going to go

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our endocrine glands don't have any

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ducts remember they secrete the hormones

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into the interstitial fluid which is

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like this part here which then diffuse

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into the capillaries which will be

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surrounding our endocrine glands

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so in this example here this looks like

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a sweat gland

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so the sweat will be produced by the

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exocrine gland taken into the duct and

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then secreted to the cells outer surface

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or the outer surface of the body

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on our right side we have our endocrine

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glands so the hormones are produced in

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that gland

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secreted into that interstitial fluid

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diffused into the blood and then they

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travel throughout the bloodstream to the

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target cells

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now the final learning objective for

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this lecture which is only a nice short

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one is to Simply identify the major

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endocrine glands so this is something

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that we will go over in the next lecture

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we will also go over in Labs but the

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first thing that I want you to know is

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to be able to identify these major

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endocrine glands before that we then go

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on to talk about what hormones they

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release and then what those hormones

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actually do

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so when we talk about the major

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endocrine glands these are the 10 glands

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that we are referring to so some are

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specific glands some are just tissues

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within other organs that secrete

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hormones

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so starting from the top and we have our

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pituitary gland so our pituitary gland

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is this structure here

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without sounding too crass it kind of

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looks a little bit like a pair of

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testicles in a full image of the brain

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it is this little structure here

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now

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showing a little bit of a close-up image

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of our pituitary gland our pituitary

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gland sits underneath our hypothalamus

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and it's made up of two distinct regions

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which each function slightly differently

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and release different hormones so this

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anterior portion or the portion to the

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front funnily enough is called our

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anterior pituitary gland the posterior

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portion or the bit which is more towards

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the back is our posterior pituitary

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gland

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so the whole structure is our pituitary

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gland the bit at the front is our

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anterior pituitary the bit at the back

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is our posterior pituitary

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moving down we then have our Pioneer

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gland so if our pituitary gland is kind

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of at the front of the brain here our

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Pioneer gland is more at the back here

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so you can see it's just that little

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white structure there

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now we're going to talk more about the

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function of the pineal gland in the next

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lecture but I just wanted to point out

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that the pineal gland actually has some

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really strong ties with the visual

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system

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which is potentially why it's so close

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to our occipital lobe at the back of the

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brain here which is where we house our

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our primary visual cortex

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we then have our thyroid gland so our

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thyroid gland sits on the anterior

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surface of the throat or the neck it

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sits just inferior or just underneath

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the thyroid cartilage which is the

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cartilage which protects our voice box

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and in males is known as the Adam's

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apple

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and then on the back of our thyroid

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gland so if this is our thyroid gland

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here we have these four dots in Grain

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and these are our parathyroid glands

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so we've had the pituitary gland

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the pineal gland the thyroid gland and

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then these four parathyroid glands which

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sit on top of that thyroid gland

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moving on we then have our adrenal

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glands so we have two adrenal glands one

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sits on top of each kidney it's a little

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bit hard to see in this image here but

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if we zoom in for a closer look here

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we've got our two kidneys here these

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little hats

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are our adrenal glands

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and much like our pituitary gland our

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adrenal gland is made up of two distinct

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regions that each have different

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functions and release different hormones

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so we are going to need you to be able

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to identify each of those two regions

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we have the adrenal cortex which is this

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outer region here

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so any time you see the word cortex in

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anatomy and physiology you know it's

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going to be the outermost layer I think

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the cerebral cortex it's the outermost

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layer of the brain so this is our

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adrenal cortex

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this inner portion here is our Adrenal

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medulla so maybe middle medulla our

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Adrenal medulla is this portion here

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we then have the pancreas and the

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pancreas is this little structure here

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which is again a little bit hard to see

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on this image but we will take a closer

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look when we talk more about the

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pancreas I kind of think it looks a

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little bit like a cob of corn it's kind

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of a bubbly yellowy color

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and the pancreas is a little bit special

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because it has both exocrine and

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endocrine functions so when we talk

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about the endocrine system we're going

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to talk about its endocrine function and

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how it releases insulin and glucagon but

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then when we get to the gastrointestinal

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system we're going to talk more about

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its exocrine function

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we then have our ovaries so in our

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female

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example we have our two ovaries here

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which sit either side of our uterus

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these produce our female sex hormones

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and then in males we have our testes

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which actually sit external to the body

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covered by the scrotum

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and they mostly produce our male sex

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hormones

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so these are our 10 hormones or sorry

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our 10 endocrine glands that we're going

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to be focusing on in the next lecture

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when we talk about the physiology of the

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endocrine system we had our pituitary

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gland at the top here which is broken

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into our anterior and our posterior

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pituitary gland

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we had the pineal gland which sits just

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posterior to the pituitary gland

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we have our thyroid gland which is this

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bit on the front of your neck

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we had the parathyroid gland which these

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four green dots on the back of the

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thyroid gland

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we have our adrenal glands which are the

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two hats that kind of sit on top of each

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kidney

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the pancreas which is the one I said

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looks a bit like a cob of corn and that

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sits kind of underneath the stomach and

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the liver and then we have our ovaries

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which we find in a female population

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and our testes which we find in a male

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population

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so now that is the anatomy of the

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endocrine system when we come to the

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physiology of the endocrine system we

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will talk more about these glands

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specifically what hormones they release

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and then the effect of those hormones on

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their target cells when those hormones

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bind to their receptors

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thank you very much

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関連タグ
Endocrine SystemHormonesHomeostasisNervous SystemInsulinGlucagonPituitary GlandThyroid GlandAdrenal GlandsPancreasReproductive Hormones
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