Apa Itu Terapi Gen? Obat COVID-19?

Summary

The video discusses the ongoing impact of the COVID-19 pandemic, highlighting its toll on Indonesia, with over 2.8 million infections and 33,000 deaths. It introduces gene therapy as a promising treatment for COVID-19 and other chronic diseases, explaining how modifying genes can potentially cure genetic disorders and cancers. Despite its potential, gene therapy poses risks, such as immune reactions and virus-related infections. The video also addresses the high cost of gene therapy, which remains a challenge, but expresses optimism about its future accessibility and development, marking it as a groundbreaking advancement in medicine.

Takeaways

• 😀 The COVID-19 pandemic in Indonesia has caused widespread suffering, including hunger, poverty, and emotional distress, with over 2.8 million cases and 33,000 deaths.
• 😀 Genetic therapy is a promising treatment being developed worldwide to treat COVID-19 and other serious diseases.
• 😀 Gene therapy involves modifying or replacing damaged genes with healthy ones to treat chronic diseases and cancer.
• 😀 The US FDA approved three types of gene therapy by 2017, with two involving using cells to destroy cancer cells or treat gene mutation-based diseases.
• 😀 One example of gene therapy is replacing the mutated p53 gene (which prevents tumor growth) to help eliminate cancer cells.
• 😀 Gene therapy can also train the immune system to recognize and attack sick cells that are otherwise ignored.
• 😀 Gene therapy has been successful in treating conditions such as hemophilia, blindness caused by retinitis pigmentosa, and severe immune system disorders.
• 😀 In 1993, the first successful gene therapy was conducted by Yanti D'Silva, who is still alive today.
• 😀 While gene therapy holds great potential, there are risks, including immune reactions, incorrect viral targeting, and potential tumor formation.
• 😀 The high cost of gene therapy is a significant challenge, as many hereditary diseases it treats are rare and require personalized treatments.

Q & A

What is the main focus of the video script?

The main focus of the video script is on the impact of the COVID-19 pandemic in Indonesia and the introduction of gene therapy as a promising treatment for various diseases, including COVID-19.

How many people in Indonesia have been affected by COVID-19 according to the Ministry of Health?

According to the Ministry of Health in Indonesia, 2.8 million people have been affected by COVID-19, with over 33,000 deaths.

What is gene therapy, and how does it work?

Gene therapy is a treatment method that involves modifying or replacing defective genes in the body to treat diseases. It can include replacing damaged genes with healthy ones or training the immune system to target and destroy sick cells.

What diseases could potentially be treated using gene therapy?

Gene therapy could potentially treat various diseases, such as cancer, cystic fibrosis, heart disease, diabetes, hemophilia, and even COVID-19.

What are some examples of conditions that gene therapy has already shown effectiveness in treating?

Gene therapy has already shown effectiveness in treating conditions such as hemophilia, blindness caused by retinal dystrophy, and severe immune system disorders.

What are the main types of gene therapy methods mentioned in the script?

The main gene therapy methods discussed include replacing mutated genes with healthy ones, fixing mutated genes, and training the immune system to recognize and attack sick cells.

What are some risks associated with gene therapy?

Some risks of gene therapy include immune system reactions, viral infections caused by the virus vectors used to deliver genes, and the potential development of tumors.

Why are viruses used as vectors in gene therapy?

Viruses are used as vectors in gene therapy because they can effectively recognize cells and deliver genetic material into them. Researchers modify these viruses to carry healthy genes instead of the harmful ones they originally contain.

What is a major challenge in gene therapy that is mentioned in the script?

A major challenge in gene therapy is its high cost, as it requires personalized treatment for rare genetic diseases and is still in the early stages of development.

How has gene therapy evolved since its first use in 1993?

Since its first use in 1993, gene therapy has evolved significantly, with experts like Vincent leading the charge in developing new treatments. However, there are still many studies being conducted to refine the therapy and make it more widely accessible.