Various type of Enteral Dosage Form

Departemen Farmakologi dan Terapi FKKMK UGM
14 Dec 202022:13

Summary

TLDRThis video provides a comprehensive overview of pharmaceutical dosage forms, including their types, advantages, and challenges. It covers various forms like tablets, capsules, liquids, and suppositories, detailing their compositions, uses, and benefits for patient compliance and drug absorption. The video explains the role of excipients, the importance of stability, and different routes of administration. It also touches on the significance of drug formulations in ensuring effectiveness, safety, and patient comfort, while addressing issues such as taste masking, ease of use, and controlled drug release.

Takeaways

  • 😀 Pharmaceutical dosage forms are developed using natural materials or chemical compounds to ensure stability, ease of use, and improve patient compliance.
  • 😀 Excipients are additional substances in drug formulations that ensure the stability, bioavailability, and correct dosage of the active pharmaceutical ingredients.
  • 😀 Pharmaceutical dosage forms can be classified based on their route of administration (oral, sublingual, rectal, etc.) and physical form (solid, liquid, etc.).
  • 😀 Powders are a cost-effective drug form that is ideal for children or adults with difficulty swallowing pills and can cover unpleasant tastes.
  • 😀 Tablets, including chewable, sublingual, and dispersible types, offer various advantages such as rapid absorption and ease of use for those with swallowing difficulties.
  • 😀 Effervescent tablets, which dissolve in water, provide a refreshing taste and are ideal for those who prefer liquid preparations but may be less practical and more expensive.
  • 😀 Slow-release tablets allow for a steady drug release over time, ensuring a consistent drug concentration and improved patient compliance, though they are costly.
  • 😀 Capsules, available in both hard and soft varieties, offer easy swallowing and the ability to cover up unpleasant tastes but are sensitive to moisture.
  • 😀 Liquid formulations like solutions, syrups, and emulsions are easy to swallow, especially for children, but can be less accurate in dosing compared to solids.
  • 😀 Rectal suppositories and solutions offer an alternative route of administration, especially for patients who cannot take oral medications due to nausea, vomiting, or unconsciousness.

Q & A

  • What is the primary purpose of pharmaceutical dosage forms?

    -The primary purpose of pharmaceutical dosage forms is to ensure the stability of the drug during storage, enhance patient compliance by improving taste, ease of use, and providing a visually appealing form. They also guarantee the drug's bioavailability and effectiveness.

  • What are excipients in pharmaceutical dosage forms?

    -Excipients are substances other than active pharmaceutical ingredients that are added to a dosage form to guarantee the stability, bioavailability, and optimal action of the drug. They play a crucial role in drug delivery and patient compliance.

  • How do pharmaceutical dosage forms improve patient compliance?

    -Pharmaceutical dosage forms improve patient compliance by making the medication easier to take, masking unpleasant tastes or odors, and offering more convenient and accurate dosing options, such as powders, tablets, or liquid forms.

  • What are the advantages of using powder as a pharmaceutical dosage form?

    -Powder dosage forms are advantageous because they are inexpensive, suitable for children and adults who have difficulty swallowing tablets, and flexible in adjusting the dose. They are also ideal for drugs that are unstable in liquid form.

  • What is the difference between sublingual tablets and regular tablets?

    -Sublingual tablets are designed to be placed under the tongue for rapid absorption through the oral mucosa, bypassing the stomach. They offer a quicker onset of action (3-5 minutes) and are useful for drugs that are poorly absorbed in the gastrointestinal tract.

  • Why are effervescent tablets used in pharmaceutical formulations?

    -Effervescent tablets contain active ingredients along with effervescent salts that release gas when mixed with water. This creates a refreshing and palatable drink, improving the taste and making the medication more enjoyable to take.

  • What are the benefits of slow-release tablets?

    -Slow-release tablets offer a sustained release of the drug, maintaining a constant drug concentration over a specific period. This reduces the frequency of doses, ensuring more consistent therapeutic effects and improved patient compliance.

  • What is the role of sugar-coated tablets in drug formulation?

    -Sugar-coated tablets provide protection against environmental factors like moisture and sunlight, mask unpleasant tastes, and improve the tablet's appearance, making it more appealing for patients.

  • What are the advantages and disadvantages of oral syrups as a dosage form?

    -Oral syrups are advantageous for children or individuals who have difficulty swallowing pills, and they tend to act faster than solid forms. However, they can be inaccurate in dosage and more expensive compared to tablets.

  • How do suppositories work as a dosage form?

    -Suppositories provide an alternative route of administration when oral intake is not possible due to factors like nausea or unconsciousness. They dissolve at body temperature, allowing the drug to be absorbed through the rectal mucous membrane for systemic or local effects.

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関連タグ
PharmaceuticalDosage FormsPatient ComplianceDrug StabilityCapsulesTabletsOral DropsPowdersSuspensionsExcipientsRectal Solutions
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