Management of Dupuytren's Contracture by Prof Chris Bainbridge

Pulvertaft Videos
22 Nov 202150:19

Summary

TLDRThis script discusses the complexities of managing Dupuytren's disease, emphasizing the importance of patient education and conservative treatment options. It highlights the limitations of surgical interventions and the potential for recurrence, advocating for minimally invasive procedures like needle aponeurotomy. The speaker also addresses various treatment approaches, including the use of radiotherapy and dynamic splinting, and the ethical considerations in obtaining informed consent for surgery.

Takeaways

  • 🔍 Dupuytren's disease is challenging to manage, with no cure for recurrence, and can cause pain, contrary to common beliefs that it's not painful.
  • 👐 Treatment for Dupuytren's contracture is primarily for functional improvement, not necessarily for a fully straightened finger.
  • 💊 Some untested treatments for Dupuytren's are available online, but they lack scientific evidence and should be approached with caution.
  • 🧪 Tamoxifen has been studied for its potential in reducing Dupuytren's recurrence post-surgery but is not recommended due to side effects and temporary benefits.
  • 🚫 Verapamil gel, though reported to have mild effects, lacks randomized controlled trials and is not widely available, making it an uncertain treatment option.
  • 🔬 Ongoing research includes the use of anti-TNF therapy for treating Dupuytren's disease, though its delivery method and systemic effects are concerns.
  • 💉 Collagenase injections were once a promising treatment but have been largely discontinued due to risks and complications, except in the United States.
  • 🤝 Conservative treatments like splinting and radiotherapy can be effective, but the choice between static and dynamic splinting should be informed by evidence and patient preference.
  • 🩺 The Digit Widget is a promising device for straightening fingers, offering a mobile and effective treatment option, though it's not available in all regions.
  • ✂️ Needle aponeurotomy is a minimally invasive procedure that can be performed safely with proper technique and is favored for its simplicity and safety.
  • 🔄 Recurrence after Dupuytren's surgery is common, and multiple treatments may lead to more complex disease in subsequent procedures.

Q & A

  • What is Dupuytren's disease and why is it sometimes considered painful despite common teachings?

    -Dupuytren's disease is a medical condition where nodules form under the skin of the palm and fingers, leading to the thickening and contraction of the fascia, which can cause the fingers to bend. It is sometimes considered painful because many patients report pain, even though it is generally taught that the condition itself is not painful. The pain is likely due to the contracture that can occur as a result of the disease.

  • Why might patients seek treatment for Dupuytren's disease even if it does not necessarily need surgical intervention?

    -Patients may seek treatment because they desire a finger that is acceptably straight, even if the level of contracture does not interfere with their function. The psychological impact or cosmetic concerns can lead them to seek medical advice and treatment options.

  • What is the prognosis for patients with Dupuytren's disease?

    -The prognosis for patients with Dupuytren's disease varies. Some patients may experience a slow progression of the disease with minimal impact on hand function, while others may have a more rapid progression that significantly impairs hand function. Treatment options, including surgical and non-surgical interventions, can help manage the condition and improve hand function.

Outlines

00:00

🤔 Dupuytren's Disease Management Challenges

The speaker begins by discussing the complexities of managing Dupuytren's disease, emphasizing the difficulty of preventing recurrence even for a genius. They highlight the misconception that the condition is not painful, despite patient experiences to the contrary. The talk also addresses the fact that not all cases require surgical intervention and that contracture, a side effect of the genetic condition, often does not impede function. The speaker uses Bill Nye as an example of someone who has successfully managed with the condition. The paragraph concludes with a discussion about the importance of patient education and the reality that not all conditions require aggressive treatment.

05:01

🧪 Untested and Experimental Treatments for Dupuytren's

This paragraph delves into various untested and experimental treatments for Dupuytren's disease found online, including some with historical roots in treating gout. The speaker mentions drugs like sildenafil, tamoxifen, and verapamil, discussing their limited evidence and side effects. Tamoxifen, for instance, showed temporary benefits that ceased post-treatment, while verapamil gel had mild effects without strong clinical trial support. The speaker also touches on the RID trial from Oxford, which tests anti-TNF therapy for treating the disease, and expresses concerns about its delivery method and potential risks.

10:02

🔬 Clinical Trials and Conservative Treatments for Dupuytren's

The speaker discusses ongoing clinical trials and conservative treatments for Dupuytren's disease. They mention the use of collagenase, which initially showed promise but was later associated with cosmetic use. The paragraph also covers the use of splintage, highlighting the lack of evidence for static splintage post-surgery and the trend towards better outcomes without it. Radiotherapy is presented as a treatment that anecdotally works, with varying degrees of success, and the speaker shares their approach to discussing it with patients. The paragraph concludes with a mention of dynamic splinting as a non-operative treatment, supported by some studies.

15:04

🛠️ Surgical and Post-Surgical Treatments for Dupuytren's

In this paragraph, the speaker focuses on surgical approaches to treating Dupuytren's disease, including dynamic splinting and the Digit Widget, a device used post-surgery to straighten fingers. They describe the process and effectiveness of using the Digit Widget, noting its benefits such as mobility during use and its ability to significantly improve finger positioning. However, the speaker also mentions the unavailability of the Digit Widget in Europe due to a lack of CE mark. The paragraph concludes with a discussion on the timing and importance of surgery in relation to other treatments.

20:06

💉 Needle Aponeurotomy: A Minimally Invasive Approach

The speaker introduces needle aponeurotomy as a minimally invasive treatment for Dupuytren's disease, which they have been instrumental in popularizing. They discuss the technique's origins, development, and their personal experiences in refining the method. The paragraph covers various needle types and techniques such as stroking the cord, slicing, and manipulation to break down the diseased tissue. The speaker emphasizes safety, feeling, and precision in performing needle aponeurotomy and shares insights on patient outcomes and the evolution of the technique.

25:07

⚕️ Surgical Techniques and Considerations in Dupuytren's Treatment

This paragraph explores different surgical techniques for treating Dupuytren's disease, including traditional fasciectomy, segmental fascia, and radical fasciectomy. The speaker reflects on the evolution of surgical approaches, moving from minimal to radical and back to more limited procedures. They discuss their personal preferences for incisions and exposure methods, the importance of avoiding damage to neurovascular bundles, and strategies for managing complex disease cases resulting from multiple needle aponeurotomies. The paragraph concludes with a discussion on the importance of patient consent and understanding the potential complications of surgery.

30:08

🩹 Wound Closure and Dermofasciectomy Techniques

The speaker discusses various wound closure techniques after Dupuytren's surgery, advocating for the use of absorbable sutures and the concept of secondary healing. They introduce the dermofasciectomy procedure, highlighting its effectiveness in reducing recurrence rates and detailing the process of performing a full-thickness skin graft from the antecubital fossa. The paragraph also touches on the Stillwell technique, a method for managing severe recurrent Dupuytren's by using the existing scar tissue effectively, thus minimizing tissue waste.

35:08

🔚 Last Resort Options for Dupuytren's Disease

In the final paragraph, the speaker addresses last resort options for managing Dupuytren's disease when other treatments have failed. They discuss the possibility of amputation as a single best option in some cases and the transformation of a three-joint finger into a two-joint finger through surgical procedures like PIP joint excision arthrodesis. The speaker also mentions the importance of considering other potential causes of pain in Dupuytren's disease, such as tender tendon sheaths, and the use of steroid injections as an alternative treatment. The paragraph concludes with a summary of the various complications that can arise from Dupuytren's surgery and the importance of informed consent.

Mindmap

Keywords

💡Dupuytren's contracture

Dupuytren's contracture is a medical condition where one or more fingers are bent and cannot be fully straightened due to thickening of the fascia in the palm of the hand. In the video's theme, it is the central focus, with discussions on its management, misconceptions, and treatment options. The script mentions that 'dupatrans is painful and yet, we generally teach that dupatrans is not, a painful condition,' highlighting the complex nature of the condition and its impact on patients.

💡Needle aponeurotomy

Needle aponeurotomy is a minimally invasive procedure used to treat Dupuytren's contracture by cutting the diseased cord with a needle. It is a key concept in the video, as the speaker discusses its benefits, risks, and techniques. The script describes the 'zen of needle aponeurotomy' and the importance of doing it safely to avoid complications like nerve injury.

💡Fasciectomy

Fasciectomy refers to the surgical removal of the thickened fascia causing the contracture in Dupuytren's disease. It is a fundamental concept in the video, with the speaker discussing various surgical approaches and considerations. The script mentions 'fasciiectomy' in the context of both primary and revision surgeries, emphasizing its role in managing the condition.

💡Collagenase

Collagenase is an enzyme that was once thought to be a promising treatment for Dupuytren's contracture, as it can break down the collagen in the diseased cords. The video discusses its history, efficacy, and side effects. The script notes that 'collagenase... had significant risks,' and its use has been limited, reflecting the ongoing search for effective treatments.

💡Tamoxifen

Tamoxifen is a medication that was trialed for its potential to inhibit the recurrence of Dupuytren's contracture after surgery. The video mentions it in the context of a randomized trial, indicating that while it showed some benefit, the effects were temporary and not significant enough for widespread recommendation.

💡Verapamil

Verapamil is a medication discussed in the video as a potential treatment for Dupuytren's contracture, though its availability and efficacy are limited. The script notes that 'verapamil gel... is reported to have some mild effect,' but also points out the lack of randomized controlled trials to support its use.

💡Splinting

Splinting involves the use of devices to immobilize or apply tension to the affected fingers, aiming to improve the range of motion in Dupuytren's contracture. The video discusses different types of splinting, including static and dynamic, and their effectiveness. The script mentions that 'static splinting or no splinting after surgery, no significant difference,' suggesting that the approach to splinting may not be as crucial as once thought.

💡Dermofasciectomy

Dermofasciectomy is a surgical procedure that involves removing the diseased fascia along with the overlying skin and replacing it with a skin graft. It is highlighted in the video as an effective treatment for recurrent Dupuytren's contracture. The script describes it as 'a well-performed dermo fascictomy... will reduce recurrence more than anything else,' emphasizing its importance in advanced cases.

💡Amputation

Amputation is the surgical removal of a part of the body, such as a finger, and is discussed in the video as a last resort for severe cases of Dupuytren's contracture. The script mentions 'amputation' as 'the single best option' in some cases, indicating that while extreme, it can be the most effective solution for patients with recurrent or severe contractures.

💡Consent

Consent in the medical context refers to the process of informing and obtaining a patient's agreement to a treatment or procedure. The video emphasizes the importance of obtaining informed consent, particularly when discussing the potential complications of surgery for Dupuytren's contracture. The script lists 'expected complications' that should be disclosed to patients, highlighting the ethical responsibility of healthcare providers.

Highlights

Dupuytren's disease management can be challenging as it often causes pain and contractures, and patients desire an acceptably straight finger rather than a fully straightened one.

The recurrence of Dupuytren's contracture after treatment is a common issue, highlighting the complexity of the condition.

Some patients with Dupuytren's disease may not need surgery, as the contracture level may not interfere with their functionality.

Untested treatments for Dupuytren's are widespread on the internet, but they lack scientific evidence and should be approached with caution.

Tamoxifen was found to inhibit recurrence of Dupuytren's after surgery in a randomized trial, but its benefits disappeared after ceasing treatment, and side effects are significant.

Verapamil gel has been reported to have mild effects on Dupuytren's when applied topically, but lacks randomized controlled trials to support its efficacy.

The RID trial from Oxford is investigating the use of anti-TNF therapy for treating Dupuytren's disease, marking a significant step in medical research.

Collagenase was once considered a promising treatment for Dupuytren's, but its use has been limited due to significant risks and side effects.

Splintage, both static and dynamic, has varying levels of evidence for its effectiveness post-surgery in Dupuytren's disease management.

Radiotherapy has anecdotal and some study support for its role in treating Dupuytren's disease, though the optimal delivery method remains unclear.

Dynamic splinting has shown promise in non-operative treatment of Dupuytren's disease, with evidence suggesting its effectiveness in straightening fingers.

The Digit Widget is a novel device for treating Dupuytren's disease, offering a mobile and effective solution for straightening fingers pre- or post-surgery.

Needle aponeurotomy is a minimally invasive procedure that has gained popularity for treating Dupuytren's disease, with a focus on safety and minimal risk.

Consent for Dupuytren's surgery is complex due to the range of potential complications, which must be thoroughly discussed with patients.

Dermofasciectomy is considered a highly effective treatment for Dupuytren's disease, particularly in cases of rapid recurrence.

Alternative treatments for Dupuytren's, such as amputation or joint modification, can be considered in severe cases where other treatments have failed.

The importance of considering other causes of pain in the hand, such as tendon sheath inflammation, in addition to Dupuytren's disease.

The Stillwell technique for dermofasciectomy is highlighted as a less wasteful and technically demanding approach to managing severe Dupuytren's disease.

Transcripts

play00:03

so i'm talking about the management of

play00:05

dupatrons tonight

play00:07

and

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i thought i'd start off with a few

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aphorisms a couple of notes so

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any full straighten a finger

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but even a genius cannot currently

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prevent recurrence and i think it's

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important to remember that

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it's sometimes painful

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and patients often get very cross about

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this because many patients will tell you

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that their dupatrons is painful and yet

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we generally teach that dupatrons is not

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a painful condition

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and dupatrons does not need to be

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treated with surgery dupatron's

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contracture is treated and that is

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really just a side effect of the

play00:50

underlying genetic condition

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and for many patients they live with

play00:56

a level of contracture that does not

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interfere with their function

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and so it's not that they want a

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straight finger but they want a finger

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that is acceptably straight

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and we have to remember that a fully

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flexed finger is actually less of a

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problem than one that is locked or fixed

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in a half extension

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if we think of bill nye the actor with

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his two fingers bent permanently down

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into the palm he has managed to win

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multiple accolades as an actor with

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these fingers locked into his palm

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frequently patients come to us because

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they don't know what is wrong they don't

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know what the prognosis is and they

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don't know what the options are they

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want advice and we offer them treatment

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we need to remember not everything needs

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treatment

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and also we need to remember that often

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for these patients

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loss of flexion after surgery is more of

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a functional problem

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than their previous loss of extension

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so what treatments are there what things

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can you offer patients well

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you probably don't want to offer them

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any of these

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these are the things that you can find

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as untested treatments listed

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all over the internet

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and i'm sure that i haven't got all of

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them

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other peonal interestingly came from a

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time when gout and dupatrons were

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thought to be almost identical diseases

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and there is now

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some

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evidence that there are links between

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them

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um

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i don't know of any evidence that uh

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sildenafil is of great benefit

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um tamoxifen uh we'll talk about in a

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moment and

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verapamil as well

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so tamoxifen interesting drug and

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there's one

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randomized trial

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using tamoxifen

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a very high dose

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showing that it did inhibit the

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recurrence of dupatrons after surgery

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the problem sadly

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was that this beneficial effect

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disappeared within two years of ceasing

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the tamoxifen and the side effects are

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not insignificant

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so

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not something that you should really be

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recommending to patients

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the verapamil gel isn't available in the

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uk it is available i believe in the

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united states i don't know about europe

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and you could if you can get it as a 15

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gel rubbed into the affected palm and

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fingers then it is reported to have some

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mild effect

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however i was unable to find any

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randomized controlled trials

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so what things are currently being

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tested

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well the rid trial from oxford

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repurposing anti-tnf for treating

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jupiter's disease

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um is

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a proper

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randomized trial

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um

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one could be cynical and say that it was

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a way of extending the patent on

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anti-tnf therapy

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which has probably earned oxford many

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millions of pounds but i wouldn't ever

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dream of doing that

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my worry about it is how it's going to

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be delivered

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um

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at the moment it's being injected into

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the nodule and that certainly reduces

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the systemic effect but

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use systemically i think would be

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associated with

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risks that would really outweigh the

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possible benefits in terms of a

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seriously

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dangerous drug

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for a benign condition

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so shin shin mentioned collagenase which

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we

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thought was the great hope of dupatrons

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at one point

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until uh it became the great hope of uh

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smoothing out your buttock creases and

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your

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various other

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cosmetic problems

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um i remember that when this

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was first mentioned uh many many years

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ago and we got a

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an email

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in the early days of email

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from the manufacturers

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and it came to the consultant meeting

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and it said would we be interested in a

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medical treatment for dupatrons

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and there was a sort of

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nah

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never going to work

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and those that know me know that my view

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is

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jump onto it see what it's like and it's

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better to do a trial of something and

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prove it doesn't work

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than to allow it to get into the wild

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and let other people

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try and see if it works

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so we we used it it it worked it's not

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perfect it had significant risks

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you can tear the skin you can

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rupture tendons you can damage

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arteries when you try to extend it i

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certainly had patients who had bruising

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all the way up the arm and down onto the

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side wall of the chest which was rather

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scary

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we moved from doing the snap at 24

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hours to doing the snap at a week

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and the advantage of that was that

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the swelling that occurred in the in the

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week or the first

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48 hours after the uh

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injection acted as a

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tissue expander

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allowed

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the skin to stretch and soften and then

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as the swelling went down

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um the skin stayed stretched so when you

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came to

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snap the collapse the

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collagen the dupatrons at

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seven days you didn't get the skin tears

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and that was very helpful

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unfortunately as i said it's been

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removed from worldwide use apart from in

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the states where it is uh highly

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expensive

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um

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but there are multiple other carginases

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that have been uh

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characterized

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and it wouldn't surprise me if we see

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another collagenase coming along in the

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future

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so

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that's the the things that are unproven

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the things that are in trial uh in drug

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treatment

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and the things that have disappeared

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what conservative treatment can you do

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well

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splintage there are papers all over the

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place of splintage

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and we've got to differentiate between

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static splintage and dynamic

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and really after surgery there is no

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evidence for static splinting

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uh the

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paper by christina jerich really was a

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landmark paper in this

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as a pragmatic paper

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static splinting or no splinting after

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surgery

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no

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significant difference between the

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splinted and the non-splinted groups

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but a trend towards a better outcome

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with no splintage

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and i think this resonated with many

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people my

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impression is that

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our nordic cousins haven't splinted for

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donkeys years and certainly

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uh my view has been to move away from

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splintage and this really pushed me away

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from splintage completely

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i now don't even split my demo

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fasciaexmiz unless i have to

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so

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other conservative treatment

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radiotherapy

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anecdotally and from the studies that

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are available it does work

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i'm not an expert on radiotherapy and my

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view is that if a patient wants to

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discuss radiotherapy i will put them in

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touch with the radiotherapist

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and leave it to the radiotherapist to

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discuss the pros and cons

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my understanding is that there are

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different ways of delivering the dose of

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different

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sources for the for the dose of

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radiation and i wonder whether that

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makes a difference to the outcome

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because certainly some people seem to

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get very prolonged benefit whereas

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others report little if any benefit

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i remember when radiotherapy was first

play10:02

suggested for treating dupatrons those

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surgeons especially plastic surgeons who

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had

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an interest in or a previous experience

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of head and neck surgery were vehemently

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against it remembering the skin damage

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from head and neck radiotherapy for skin

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cancer for

play10:21

intraoral cancer

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but this is very different much lower

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and the skin does become dry

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i think that's a universal

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skin is a sort of dry feeling

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but i've certainly seen no problems with

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wound healing after radiotherapy

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not large numbers because it does seem

play10:43

to

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reduce the rate of progression

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but uh

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probably half a dozen somewhere between

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half dozen and 10 patients over the

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years

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it doesn't

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cause regression of the dupatrons so you

play10:58

need to discuss with your radiotherapist

play11:01

how you're going to manage any existing

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contracture are you going to do a needle

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upon your otomy are you going to do open

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surgery are you going to do collagenase

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if you have it available and then decide

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uh at the timings of the radiotherapy

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um

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what i've done is discuss with the

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radiotherapist when they want to give it

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and then we will schedule a patient for

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a simple needle of ponerotomy get the

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patient the finger straight or the

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fingers and then deliver them to the

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radiotherapist a few weeks later

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so dynamic splinting

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there are a number of studies of dynamic

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splinting from

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simple occupational therapy splints

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uh to more complex

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and

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one study showed that uh of the three

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groups uh three different types of

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splinting

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it did not influence the natural course

play12:01

of the disease after operation

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but others

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uh this one from aniline bronze uh luke

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the smear etc

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showed that

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tension and compression orthotic devices

play12:13

can be used as a non-operative treatment

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of dupatron's disease

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in both early untreated and aggressive

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post-surgery

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so there is evidence that dynamic

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splints will work and straighten fingers

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in terms of

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surgically applied dynamic splinting

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this i think was in some ways the

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landmark paper

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uh from messina and messina

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um this rather complex

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erection of meccano

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slightly more

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streamlined on the right hand side

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and they were able to confirm complete

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extension of the severely contracted

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fingers

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my personal experience is that it's

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difficult to apply

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i certainly found difficulty in getting

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these two pins into the fifth metacarpal

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on a reliable basis

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um

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i think i remember one metacarpal

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fracture from perhaps too many pins

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being inserted

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and i know of other surgeons that also

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had fractures

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this was in the days before we had small

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mini c arms so it may be different today

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but

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something that demonstrated the utility

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of dynamic traction but really hasn't

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stood the test of time

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perhaps of more interest currently

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is the digit widget now those of you

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that have been to the american han

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society meetings uh will have seen

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the hand innovations uh

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installed and the

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multiple different devices developed by

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the team there

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but this digit widget is fascinating

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uh you put two pins into the dorsal of

play14:15

the middle metacarpal

play14:17

there's a jig for doing this

play14:19

you do it under fluoroscopy

play14:21

and then you have a

play14:25

wrap

play14:26

of lycra and

play14:28

um

play14:31

sticky back plastic

play14:32

on the back of the hand and this uh

play14:37

device is uh then applied to it and

play14:39

these are

play14:41

mandibular

play14:42

bands used after intraoperative surgery

play14:46

and

play14:47

as you can see

play14:48

we take a post-surgery um

play14:52

jupiter's and over a period of uh six

play14:55

weeks get it to a virtually straight

play14:58

position

play15:01

and then at about

play15:03

10 weeks operate on the finger with a

play15:06

flashy ectomy or skin graft and then

play15:10

they recommend leaving it on for a

play15:12

further period after that

play15:14

the beauty of this of course is that

play15:16

it's mobile so the patient can still

play15:18

keep their movement

play15:20

whilst they've got it on

play15:22

and uh

play15:23

it's very effective i was fortunate to

play15:26

be able to get two of these devices uh

play15:29

some years ago and i can confirm that

play15:33

they will straighten any finger

play15:35

so i

play15:37

put one of them on to a patient with a

play15:40

third time recurrent dupatrons of the

play15:41

little finger uh down into the uh the

play15:45

palm and over eight weeks we managed to

play15:48

get it out completely straight

play15:50

and then i went ahead with a

play15:52

dermafasciaectomy

play15:56

unfortunately it's not available in

play15:58

europe

play15:59

there's no ce mark

play16:02

so

play16:02

not currently available but the concept

play16:05

is there

play16:06

the problem

play16:09

with with the dynamic traction though is

play16:11

that if you take the

play16:13

diatraction off before you do the

play16:15

surgery it will very rapidly recur

play16:18

now whether that's because the extensor

play16:21

tendon is incompetent or whether you

play16:26

stretch the dupletrons and then it

play16:28

fights back against you when you take

play16:31

the traction off i'm not sure

play16:34

but fundamentally it's a pre-surgery

play16:37

treatment or a post-surgery treatment

play16:40

not an alternative to surgical treatment

play16:46

so we've covered the various drugs that

play16:50

you can

play16:52

look up on google if you are a patient

play16:56

we've covered the various forms of

play16:58

conservative treatment and the

play16:59

pre-surgery treatment

play17:01

but what else can you do

play17:03

a needle upon eurotomy shin chin said

play17:06

that i have popularized it

play17:08

i've certainly been keen on it

play17:12

and

play17:13

it's one of those things that

play17:17

wasn't invented by surgeons much to our

play17:19

discomfort it was uh really

play17:23

i suppose invented by baron dupatron

play17:25

this is what he did he did a needle upon

play17:28

neurotomy but with a bishopri um a

play17:31

jeweler's knife

play17:33

bisjutri

play17:34

but it was re reinvented or rediscovered

play17:37

by a group of rheumatologists in

play17:41

paris

play17:42

there was certainly a dermatologist in

play17:44

london doing needlepoint rotary very

play17:47

successfully for many years

play17:50

but

play17:51

was associated in the mind of most

play17:53

surgeons with a high risk of pref

play17:56

digital nerve injury

play17:59

incomplete release and complications

play18:04

so i started doing needle apology

play18:08

around the time of collagenase

play18:10

just before collagenase became available

play18:12

and we started the trials

play18:15

and

play18:16

really it just took off

play18:18

um i think i'd had a patient that said

play18:21

they'd been to paris

play18:23

had had it done there would i do their

play18:26

other hand and i said oh well okay let's

play18:28

give it a try

play18:29

started in the palm

play18:32

and then gradually moved out into more

play18:34

complex cases

play18:36

and

play18:37

patients just talked to each other and

play18:40

within a few months i had a queue out

play18:42

the door of patients wanting needle upon

play18:45

your offspring which meant that i had to

play18:46

get very good at it very quickly

play18:51

then

play18:52

venus and i

play18:53

prepared a video

play18:55

one for patients on

play18:57

what they need to know and the second

play18:59

one for

play19:01

surgeons

play19:03

my

play19:04

view is that

play19:06

treat the parma chords and you can do

play19:08

this even in the context of doing a

play19:11

fasciectomy you know that the palmer

play19:13

chords in primary disease will be

play19:15

superficial to the

play19:18

transverse fibers the nerves are going

play19:20

to be safe

play19:21

and so

play19:22

with an anaesthetised patient just

play19:25

before you start doing the fasciectomy

play19:28

practice your needle upon your otomy in

play19:30

the palm

play19:31

see the benefit it gets and then go

play19:34

ahead with your fasciaectomy exploring

play19:37

waved under your

play19:38

your needle upon your otomy confirming

play19:41

the release or seeing how you've

play19:44

missed parts of it

play19:46

and then as you get uh

play19:48

better at it you could perhaps do needle

play19:51

a ponyotomy in the palm for a complex

play19:53

disease patient prior to surgery

play19:57

help straighten the finger out partially

play19:59

and then bring them in for a more

play20:01

limited fasciaectomy in the finger for

play20:03

example

play20:05

and then you can work your way out

play20:07

towards the pip joint and even towards

play20:10

the dip joint

play20:14

on this side you can see a range of

play20:16

needles

play20:17

i use blue needles

play20:19

almost universally

play20:21

i don't use green needles except

play20:24

occasionally in the palm i think they're

play20:26

slightly too big

play20:28

and i use orange needles at the pip

play20:31

joint and beyond just because they're

play20:33

shorter and they're more precise

play20:37

be careful that you don't get given

play20:40

needles that are too long if you get a

play20:42

blue or orange needle that's too long

play20:45

then it'll be too whippy and you won't

play20:47

actually get feedback from the tissues

play20:49

as to what you're doing

play20:55

choose your portal site for the needle

play20:57

of ponerotomy with care

play20:58

you don't want to do it where the skin

play21:01

is adherent to the underlying

play21:03

dupertron's chord if you do

play21:06

you'll get a skin tear because there's

play21:08

no possibility of extension

play21:10

so what you want to do when you're

play21:12

starting

play21:14

is to put tension on the finger and look

play21:17

for where the skin remains pink

play21:20

so

play21:21

stretch it the finger out

play21:23

get most of it to blanch and you'll see

play21:25

where the skin is not under tension

play21:28

by it remaining pink and that's where

play21:30

you put your portal

play21:33

you can start approximately obviously i

play21:35

prefer to start distally

play21:37

that means that

play21:39

if i do happen to anesthetize the

play21:41

digital nerve

play21:43

when i come to the next most proximal

play21:45

portal the nerve will not be

play21:47

anesthetized at that point and i'll

play21:49

still get

play21:50

an electric shock

play21:52

from sensation in the patient if i touch

play21:55

the nerve

play21:57

but that is relatively rare um

play22:01

the important thing is to

play22:02

only have a short part of the needle in

play22:05

the finger so you know what you're doing

play22:10

these pictures were drawn by a medical

play22:12

student who is working with us and uh to

play22:15

show the various methods

play22:18

if you've got a lovely mature jupiter

play22:20

trans chord then simply

play22:23

putting the neat the chord under tension

play22:25

and pushing the needle into the cord

play22:28

will start to cut it and you'll

play22:31

sometimes feel the cord just giving way

play22:33

as you push the needle in and it's a

play22:35

lovely feeling

play22:37

and you can feel the finger

play22:38

straightening out each time you do it

play22:42

and this is what the

play22:44

french rheumatologists were doing they

play22:46

were simply

play22:47

putting the knee pushing the needle into

play22:49

the cord hundreds of times

play22:52

but frankly it doesn't work for every

play22:54

chord and it gets boring very quickly

play22:57

and we're surgeons so we can do better

play23:00

so the next uh technique that i

play23:03

developed was to stroke the chord

play23:06

if you put the tip of the needle on the

play23:08

very surface of the cord and just slide

play23:11

it backwards and forward so you're just

play23:13

tilting the needle side to side no

play23:15

pressure at all

play23:16

um then it will just scratch its way

play23:18

through the cord

play23:21

i call this the zen of uh needle of

play23:23

plenty there's no force to it it just

play23:26

flows

play23:27

uh and again

play23:30

if you aren't just feeling that scratchy

play23:33

nature of the chord

play23:34

stop

play23:37

needle ponyotomy is supposed to be safe

play23:40

it's a minimally invasive procedure

play23:43

stop whenever you're not sure what

play23:46

you're doing

play23:47

not sure what you're cutting and you're

play23:49

not sure where the needle is any one of

play23:52

those if you don't stop will lead you

play23:54

into disaster

play23:56

so stroking the cord

play23:59

very helpful

play24:00

the next one is is what i call the slice

play24:03

now if you've got a cord that is uh thin

play24:08

um then you can't stroke across the top

play24:10

of it

play24:11

but if you put the needle down the side

play24:14

and then just put a little bit of

play24:16

tension on the needle so that as it

play24:19

comes up

play24:20

it flicks

play24:21

then it will start to cut through a

play24:23

narrow cord

play24:25

and that's what we're trying to

play24:26

demonstrate here so you can see that

play24:28

i've got a little bit of bowing on that

play24:31

needle not very much just a slight

play24:34

amount

play24:34

so that as it lifts up it will slice its

play24:38

way across it

play24:39

and you just keep on repeating that

play24:42

doing it from each side in turn until

play24:45

you uh feel the cord go

play24:49

and then manipulation and this is either

play24:52

the most scary part of needle ponyotomy

play24:54

or the most enjoyable part of needle

play24:56

upon rotary

play24:57

or both

play25:00

you get to the point where you know that

play25:03

you've got through the vast majority of

play25:04

the chord with your needle you know that

play25:07

you're not really feeling

play25:09

clearly any more

play25:12

called to be cut but it hasn't quite

play25:14

come straight

play25:16

is this

play25:17

the joint that's stiff or is it still

play25:20

called

play25:21

if you can't feel a defect in the chord

play25:24

then there's still some remnants of the

play25:26

chord

play25:27

and if you isolate the joint so you uh

play25:31

you if you're doing a pip joint flex the

play25:33

mp joint and then straighten just the

play25:36

pip joint

play25:38

you will get this

play25:40

snap as we call it if you're lucky it

play25:43

will sound like like a ripe carrot just

play25:46

snapping in half and everybody in the

play25:50

room will jump

play25:52

otherwise it will just ease out i don't

play25:54

think there's any difference in the long

play25:56

term outcome between the two

play25:58

um and then as soon as you've done that

play26:00

you'll be able to feel a defect between

play26:02

the ends of the cord

play26:04

and when you stretch the finger

play26:07

the skin that was under that wasn't

play26:10

under tension

play26:12

and

play26:13

stayed pink when you stretch the finger

play26:15

will now go white showing that you've

play26:17

taken up all of the elasticity in the

play26:20

skin

play26:22

so that's uh needle upon neurotomy

play26:26

um for me it's one of the most enjoyable

play26:29

uh parts of dupatron's treatment it's

play26:32

simple

play26:33

it's safe

play26:34

and i always say to patients that if i

play26:38

can't feel what i'm doing safely or i

play26:41

get lost in the finger we will stop

play26:44

we will reassess

play26:46

and we'll either go for surgery or the

play26:49

patient can live with what we've already

play26:51

achieved i'm not there to get perfection

play26:54

in complete extension i'm there to get

play26:57

an improvement

play26:58

with minimal risk and minimal damage

play27:03

so let's move on to the more traditional

play27:06

uh

play27:07

surgery

play27:09

and

play27:10

there's a variety of these from

play27:12

segmental fascia to me limited

play27:14

fascictomy and even radical fascictomy

play27:18

now um radical fasciectomy has really

play27:21

fallen out of uh

play27:23

favor

play27:25

very much like most other forms of

play27:27

radical surgery and i

play27:29

i look at uh almost all forms of surgery

play27:32

as going through this evolution from

play27:35

pre-anaesthetic days of minimal surgery

play27:38

that was often very fast

play27:40

get the minimum necessary done

play27:43

and then with the introduction of

play27:44

anaesthesia

play27:46

we saw

play27:47

surgeons moving into radical surgery so

play27:50

with breast cancer we moved from

play27:53

mastectomy to the radical to the whole

play27:55

sense mastectomy

play27:57

and then we realized it didn't work

play27:59

and so we now see things changing back

play28:02

and with chemotherapy and

play28:05

radiotherapy we can move back to

play28:08

more limited surgery but equal cure

play28:11

rates or better cure rates even

play28:14

and similarly with dupatrons uh we went

play28:18

from uh

play28:19

small

play28:20

treatments with uh dupatron

play28:24

the introduction of anesthesia allowed

play28:25

fasciaectomy and then radical fascictomy

play28:28

where the whole of the skin of the palm

play28:30

was

play28:31

elevated

play28:33

and the fascia

play28:35

excised on block

play28:38

often associated with a real

play28:42

high incidence of wound necrosis

play28:46

long-term healing

play28:47

but also associated with

play28:50

very highly successful treatment

play28:53

my grandfather had a radical fascectomy

play28:57

probably back in the 30s or

play29:00

40s

play29:01

uh healed perfectly never had any

play29:03

long-term problems never had recurrent

play29:05

dupatrons

play29:07

um

play29:08

thankfully for me it didn't pass down

play29:10

the family and at the moment touchwood i

play29:13

have no signs

play29:16

but we have to

play29:18

think what do we mean by jupiter's what

play29:20

do we think of the disease process

play29:23

are we looking at a disease of specific

play29:26

parts of the fascia in which case we

play29:28

want a narrow margin around the cord or

play29:31

are we say seeing this as a disease of

play29:33

the whole fascia in which case we want a

play29:36

radical excision

play29:39

we want to look at recovery for the

play29:41

patient the time to recovery versus the

play29:44

recurrence rate and there's very little

play29:46

information on which to based any

play29:48

decisions we talk about the dupatron's

play29:51

diathesis

play29:53

but we don't really know what that means

play29:57

and one of the problems from needle upon

play30:00

your other me and those of you that do

play30:02

need a leuponorotomy and do it regularly

play30:05

and have been around for the 27 years

play30:08

that shinshin reminded me that i've been

play30:10

a consultant for thank you shinchan

play30:13

will know that

play30:14

multiple needle upon your ottomans will

play30:17

lead to more complex disease

play30:20

and so

play30:22

whilst needle upon your otomy is i think

play30:25

excellent and patients like it

play30:27

you have to be aware that

play30:30

if you've done it two or three times or

play30:32

even four times in a finger

play30:34

when you finally come to do the

play30:36

fasciectomy

play30:37

you will have a long job it will be

play30:40

complex you'll have more retrovascular

play30:43

chords you'll have more spiral bands and

play30:46

you'll be working hard for your money

play30:53

get uh two surgeons together to talk

play30:56

about dupatrons and you'll probably end

play30:58

up with three different uh approaches

play31:00

um i personally like them akash

play31:04

and scoob but then i'm old-fashioned

play31:08

i used to think that the bruno approach

play31:10

was

play31:11

not a good approach for dupatrons

play31:14

but many of my colleagues

play31:16

who i really respect uh have used the

play31:20

bruno incision and made it work for them

play31:24

the lateral approach

play31:26

donald summit is i think very

play31:29

much in favor of the lateral approach

play31:31

and i think it does have its place i

play31:33

think if you've got a unilateral cord

play31:36

with an

play31:37

inexperie sorry with an experienced

play31:40

surgeon

play31:41

then

play31:42

distal to proximal

play31:45

through a lateral incision can be very

play31:47

effective

play31:50

but if you're an inexperienced surgeon

play31:52

then i would still recommend

play31:55

the skoog approach i think it's more

play31:57

extensile

play31:59

in its exposure than the bruner

play32:02

and the makash now why the mccash

play32:05

and it's it's one of those exposures

play32:07

that comes and goes in and out of

play32:09

fashion

play32:11

for those of you that aren't aware of

play32:13

what the cash is it's a transverse

play32:15

incision in the palm

play32:17

somewhere around the distal palmar

play32:20

crease

play32:21

and you just

play32:23

open it up raise your skin flaps

play32:26

and then carry on with either a brunner

play32:28

or a screw and you leave it open at the

play32:31

end of the procedure

play32:33

you have to warn the patient you've left

play32:35

a great big hole in the palm of their

play32:36

hand otherwise they and your nursing

play32:39

staff get very upset uh later on

play32:42

when they come for their first dressing

play32:44

change but it will heal in about 10 days

play32:46

to a fortnight and

play32:49

fascinatingly it leaves

play32:51

virtually no scar you cannot see where

play32:54

it is

play32:55

where it has happened

play32:58

i think it has uh

play33:00

three advantages

play33:02

firstly it allows you to have a drainage

play33:05

portal so that you won't get

play33:08

hematomas uh i know that they aren't

play33:11

common in uh dublin surgery but it just

play33:13

gives me that little bit of extra

play33:16

sleep at night

play33:18

secondly it takes the tension out of the

play33:22

fingers so that

play33:24

this you get a little bit of movement of

play33:27

the web spaces

play33:29

into the fingers

play33:31

because all of this skin has moved

play33:33

forwards so i think it aids

play33:36

extension of the finger at the end of

play33:38

the procedure

play33:39

and

play33:40

finally i think it takes tension off the

play33:44

sutures

play33:45

so that when you ask the patient to

play33:47

extend their fingers they don't get that

play33:50

tension from the from the sutures

play33:55

but finally on this slide we've got to

play33:57

talk about what you're going to do with

play33:59

the neurovascular bundles now the

play34:01

neurovascular bundles

play34:02

we know are

play34:04

collateral damage in jupiter surgery two

play34:08

patrons is not about the neovascular

play34:10

bundles but we have to know where they

play34:13

are

play34:14

in order to exercise the duplicates

play34:15

safely and every trainee is told that

play34:18

they have to look out for spiral bands

play34:21

and that if they cut the digital nerve

play34:23

whilst we

play34:24

uh through a spiral band they will be

play34:27

damned forever and the drummed out of

play34:29

hand surgery uh and it will be a big

play34:32

black mark

play34:34

well

play34:36

my view is that actually

play34:38

doing dupertrons i just don't want to

play34:41

see the neurovascular bundle unless i

play34:43

have to

play34:44

so in primary disease i will be doing

play34:47

everything i can not to see the

play34:49

neovascular bundle

play34:51

the neovascular bundle's

play34:53

surrounded by fat it's under no tension

play34:56

in jupiter's disease

play34:58

so even if you push your knife against

play35:01

the neovascular bundle you won't damage

play35:03

it

play35:04

and if you can leave that perineural fat

play35:08

alone it will prevent scar tissue

play35:10

forming around the nerve

play35:12

and mean that when you come to do your

play35:14

revision surgery

play35:16

you will still have a virtually pristine

play35:18

nerve to dissect out a functioning

play35:22

artery

play35:23

if you make it your life's work to

play35:26

demonstrate the neurovascular bundle

play35:28

even in primary cases

play35:30

you will be very sad when you come to do

play35:33

the revisions because it will already be

play35:35

scarred

play35:36

so

play35:37

know where the digital the neurovascular

play35:40

bundles are

play35:41

but just leave them there let sleeping

play35:43

dogs lie

play35:47

and then closure

play35:49

well there's as many different ways of

play35:51

closing a wound as there are

play35:54

different surgeons

play35:56

uh zed plasti or v to y

play36:00

um clearly as a proponent of the skoog

play36:03

approach i like z plastics

play36:06

one single large zed plasti in the

play36:08

proximal compartment uh nothing fancy

play36:12

don't move

play36:13

skin from the palm into the finger so

play36:15

it's not

play36:16

formed on the palmer digital crease it's

play36:19

formed in the middle of the proximal

play36:21

compartment

play36:24

then close all gaps or allow secondary

play36:26

healing um

play36:28

when i was uh a young surgeon

play36:31

um

play36:32

then i was taught that you had to close

play36:34

all gaps

play36:36

so everything had to be closed

play36:38

and if the gap couldn't be closed

play36:40

you had to put a skin graft on it

play36:42

and then i think

play36:45

coming from the congenital hand surgery

play36:47

world we had the

play36:49

concept of secondary healing especially

play36:51

for

play36:53

syndactyly release where people were

play36:55

simply joining the apices of their

play36:58

zigzags

play37:00

and now

play37:01

i'm really very happy to leave gaps in

play37:03

dupatrons if i will close the apc's i

play37:07

might do a running stitch but if it's

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tight just leave it

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i use absorbable sutures

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i think there's a number of reasons

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firstly patients like absorbable sutures

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patients dislike having sutures removed

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and if you've ever had sutures removed

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from a slightly gooey wound it's painful

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secondly

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in times when

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nurses in clinic are in short supply run

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off their feet

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why give them extra work

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it takes hours sometimes to take sutures

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out of that jupiter patients

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absorbable doesn't matter

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dressings

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whatever you like

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plaster of paris no

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splints no

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further dressings

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whatever you like

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um increasingly i'm thinking that what

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we should be doing to these patients

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is treating them like either burn scars

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or

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hypertrophic scars

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and that we should be in the immediate

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post-operative period once everything's

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healed

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putting them into

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compression orthoses compression gloves

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with

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silicon

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inserts to control scarring

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but that's something that

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when we have limited therapists is again

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difficult

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and then we come on to the uh

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the

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big daddy of them all the

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dermofascictomy

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um so andy logan in

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norwich uh produced a lovely paper a

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number of years ago showing that a

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well-performed dermo fascictomy

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will reduce uh recurrence

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more than anything else

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and here we can see a series of

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photographs there's the dupatrons um

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the skin graft are switched into place

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the tie of addressing

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and then

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final appearance

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it works it's a brilliant treatment

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um

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and

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there are

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some people who think that it should be

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done fairly early i prefer to keep the

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patient's natural skin and so i'll often

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keep it for the

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third revision but

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if i get

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rapid recurrence so if i get recurrence

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after surgery at three to six months

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which does happen

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so

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uh there's a

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a feeling i think among surgeons that uh

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if they see that uh rapid recurrence the

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patient that you've done a beautiful

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operation on and they've come back three

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months later to your clinic and their

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fingers back down again

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oh

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what do i do

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they're the ones to do a dermal fascia

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etch me on even if it's the first

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recounts just do a dermal fascia

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activity

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full thickness versus split it's got to

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be full thickness

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um there's papers about using integra

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and they're split skinny graft on top um

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but just do a full thickness

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i use the anti-cubital fossa it's thin

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mobile skin there's plenty of it

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uh it leaves a scar in the lines of

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election that's invisible uh i think

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taking uh full thickness grasp from the

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side of the forearm is a horrible scar

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it's a tight wound it's uh it's

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um hypothena eminence

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equally but even more

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so for me full thickness and a cubital

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fossa

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if you want to show off how good you are

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then you take it

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leaving the reety pegs behind so you can

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see the

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the uh

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the tracery

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and you don't d-fat a couple of fat

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globules on your skin grafts will make

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no difference to the take

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whereas taking your scissors and uh

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meticulously taking off every bit of fat

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from your skin graft will certainly

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crush and damage it

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so sharp knife

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lots of tension

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and lift the skin graft in one piece

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but the standard description of

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demofascectomy

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is to excise

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the original scar

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but then you've thrown away tissue

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and

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my personal preference

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uh that i've done for

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27 plus years is what i call the

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stillwell technique

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uh those of you that work in the north

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of england

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or certainly the north west

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may remember john stillwell a plastic

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surgeon

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who taught me this technique uh

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during

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his time and my time at writington

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it's a difficult technique it's

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technically demanding

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it protects the pip joints

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particularly

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and it comes i think uh from the concept

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of burn scar management and this is a

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picture that i found under the

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management of burn scar

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on a neck where we don't cut out

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this whole scar

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we simply incise it

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let it retract

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and then fill in the gap

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this is a picture of a burn scar and a

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finger in a child and you can see the

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similarity to severe

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recurrent dupatrons with this shortage

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of skin

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and here

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traditionally you would open this up

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you would release these

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flaps of scar tissue back to the

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mid-lateral line

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and then you would in layer graft

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what uh

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i do um and i i don't have a picture of

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this i've gone through all my slides and

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it it's something that i do so routinely

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that i've never thought to photo it or

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to photograph it

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so if you start in the middle of the uh

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middle phalanx at the mid lateral line

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and

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draw your incision

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right down into the palm and you want to

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be proximal or just proximal to the edge

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of your previous scar tissue

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and then down the

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other mid-lateral line

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by being just proximal to your level of

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scar tissue this allows you to go down

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and find your neurovascular bundles in

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good tissue

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and then you lift this whole flap of

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skin scar dupertrons whatever

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off the neovascular bundles off the

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tendon sheath

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just sliding it distally

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now this looks as if it's going to be a

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massive flap that is

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far more than one to one um it's going

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to have very poor blood supply and it's

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made of scar tissue and deuterons

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well it does in this picture but if you

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imagine doing it in this hand

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it's going to be a very short

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piece of tissue

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it is virtually going to be one to one

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by the time you've raised it

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and it always survives if you're worried

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you can let down the tourniquet

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and inspect the proximal edge of it and

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it will bleed

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the big advantage is that as you dissect

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this out

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and you start releasing the pip joint

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and you open the tendon sheath as we

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always end up doing

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and then you're worried about putting

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your uh

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skin graft on it will it take over the

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tendon

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this flap

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always just sits

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over the pip joint crease and then you

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put your big skin draft

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down in here

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so you have the advantage that you

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haven't thrown any tissue away

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you've kept and used that tissue and

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you've used it where your skin graft

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will have the poorest take

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so it's demanding

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it's not something to jump into unless

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you're very happy with dissecting out

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along the neovascular bundles but i

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think it actually gives a much better

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result in terms of derma fashion ectomy

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and is less wasteful

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so

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what are the last rites of dupatron's

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amputation

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and sometimes it is the single best

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option

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sometimes just amputate the finger

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amputate the finger keeping a long

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dorsal flap

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and fold that dorsal flap down into the

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palm resurfacing

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previously scarred tissue in the palm

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uh dorsal tissue

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doesn't have dupertrons well yeah it

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does uh the pads but

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effectively it doesn't so folding it

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down into the palm gives you lots of

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skin

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and gives you a fire break if nothing

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else

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the other one that

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people don't think about but which i

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think can be very useful

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is to turn a three finger joint and a

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three finger three joint finger

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into a two joint finger

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and you can do this in uh two ways

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what i prefer to do is a pip joint

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excision arthrodesis and

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what i

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do is open from the back so you're going

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through

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virgin territory

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and you excise proximal phalanx and

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middle flanks

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until the finger will come straight

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again

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and then you simply put a plate on it

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reef your extensor tendon close up and

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you've shortened the finger

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usually by about a phalanx in length

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but you've got a finger that is straight

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all the jupiters is relaxed

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and it's got one joint at the

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appropriate place for the finger to

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function

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an alternative that i have come across

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is that in a situation like this

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you'd

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take out the middle phalanx

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keeping all of the collateral ligaments

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to keep the collateral ligaments at the

play47:50

dip joint on the distal phalanx

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the pip joint on the proximal phalanx

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and you bring the distal phalanx to sit

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on top of the proximal phalangeal head

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repair your collateral ligaments

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[Music]

play48:04

refuel extensor tendon and again produce

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a two-joint finger

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of a shorter length

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but removing the contracture

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um

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i think that's more complicated than my

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one but my one has an occasional

play48:20

non-union rate

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so

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uh two options

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one of the big problems i think in

play48:27

duplicate surgery is consent

play48:31

and the complications

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this is the list of expected

play48:35

complications

play48:37

from limited fascictomy surgery in the

play48:40

disc trial

play48:44

amputation arterial injury bleeding

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complex regional pain syndrome delayed

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healing infection instability nerve

play48:51

injury pain parasthesia scar pain

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scarring

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medicine ecosystem carpal tunnel

play48:56

syndrome tina synovision trigger finger

play48:59

um so

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if you're not

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telling patients about these risks

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then you aren't telling them

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about what a nationally funded ethically

play49:11

approved study

play49:12

considers expected complications

play49:17

mention of trigger finger reminds me

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of another slide which i thought i had

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or a point that i've missed out which is

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that

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whilst dupatrons may be painful not all

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pain in dupatrons

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is dupatrons think of other things

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and my colleague dan armstrong has

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really brought home to me in his

play49:38

discussions

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that a tender nodule in the palm in the

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line of the ring finger

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is frequently a tender tendon sheath and

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a1 pulley rather than a tender nodule

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and

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dan has had great success with some of

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these patients with a steroid injection

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into the tendon sheath

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rather than injecting

play50:02

nodules

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and that reminds me we've not talked

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about injecting nodules

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probably because i don't like it and i

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think it's a waste of time

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and i think it's very very painful

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and that seems to brought me to the end

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Dupuytren's DiseaseSurgical TreatmentNon-Surgical OptionsNeedle AponeurotomyCollagenaseFasciectomyRadiotherapySplintingPatient CareHand SurgeryMedical Management
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