Bagaimanakah tahapan Rantai Transfer Elektron dan Kemiosmosis?

Biologi Aja!
20 Apr 202007:30

Summary

TLDRThis educational video delves into electron transport chains and chemiosmosis, the final stage of aerobic respiration, where most ATP is produced. It explains the conversion of NADH and FADH2 from previous stages into usable energy by the body. The video outlines the location of these reactions in the inner mitochondrial membrane, detailing the role of complexes and enzymes in electron transfer and the creation of a proton gradient. It also clarifies the difference between NADH and FADH2 in ATP production, concluding with a calculation of total ATP yield from aerobic respiration, highlighting the significance of this process for cellular energy.

Takeaways

  • 🌿 **Electron Transport Chain and Chemiosmosis**: The final stage of aerobic respiration where most of the ATP is produced.
  • 🔋 **Energy Conversion**: NADH and FADH2, produced in previous stages, are converted into ATP, the usable form of energy for the body.
  • 📍 **Location of Reaction**: These reactions occur in the inner mitochondrial membrane, also known as the 'cristae'.
  • 🛠️ **Components of the Inner Membrane**: Includes a phospholipid bilayer, Complex Protein 1, Coenzyme Q or ubiquinone, Complex Protein III, Cytochrome C, and ATP synthase.
  • ⚡ **Electron Transfer**: Electrons are transferred from one protein complex to another, with oxygen acting as the final electron acceptor.
  • 💧 **Formation of Water**: The process ends with the combination of oxygen with hydrogen ions to form water, which is expelled from the cell.
  • 🔄 **Differences in Electron Transfer**: NADH and FADH2 have slightly different processes in terms of electron transfer and the number of ATP produced.
  • 🔗 **ATP Production from NADH**: For every NADH molecule, three ATP molecules are produced through a series of electron transfers and proton movements.
  • 🔗 **ATP Production from FADH2**: Each FADH2 molecule results in the production of two ATP molecules through similar electron and proton movements.
  • 🔍 **Total ATP Yield**: In aerobic respiration, a total of 38 ATP molecules are produced, considering the ATP generated in glycolysis, oxidative decarboxylation, and the Krebs cycle, minus the 2 ATP used for transport into the mitochondria.

Q & A

  • What is the main topic discussed in the script?

    -The main topic discussed in the script is the electron transport chain and chemiosmosis, which is the final stage in aerobic respiration where most of the ATP is produced.

  • Why is it necessary to convert NADH and FADH2 into ATP?

    -NADH and FADH2 are high-energy molecules that cannot be directly used by the body. They need to be converted into ATP, which is a usable form of energy for the body.

  • Where do the electron transport chain and chemiosmosis occur within the cell?

    -These processes occur within the mitochondria, specifically on the inner mitochondrial membrane, also known as the cristae.

  • What is the role of oxygen in the electron transport chain?

    -Oxygen acts as the final electron acceptor in the electron transport chain, combining with electrons and hydrogen ions to form water.

  • What are the key components of the inner mitochondrial membrane involved in the electron transport chain?

    -The key components include Complex Protein 1, Coenzyme Q or ubiquinone, Complex III, Cytochrome C, and ATP synthase, as well as Complex Protein 2.

  • How does the process of converting NADH to ATP differ from FADH2 to ATP?

    -In the conversion of NADH to ATP, electrons pass through Complex Protein 1, Coenzyme Q, Complex III, Cytochrome C, and Complex Protein 4, releasing more hydrogen ions. In contrast, FADH2 directly enters the chain at Complex Protein 2, and its electron transfer does not trigger the release of hydrogen ions to the same extent.

  • What is chemiosmosis and how is it related to ATP production?

    -Chemiosmosis is the process by which the movement of protons (H+) back into the mitochondrial matrix through ATP synthase drives the formation of ATP. It is the mechanism by which the potential energy stored in the proton gradient is converted into chemical energy in ATP.

  • How many ATP molecules are produced from the conversion of one NADH and one FADH2?

    -For every NADH molecule, three ATP molecules are produced, while for every FADH2 molecule, two ATP molecules are generated.

  • What is the total ATP yield from aerobic respiration, considering glycolysis, the oxidative decarboxylation, and the Krebs cycle?

    -The total ATP yield from aerobic respiration is 38 ATP, considering 2 ATP from glycolysis, 6 ATP from oxidative decarboxylation (2 NADH), and 24 ATP from the Krebs cycle (6 NADH, 2 FADH2, and 2 ATP directly).

  • Why is the total ATP yield sometimes cited as 36 ATP instead of 38 ATP?

    -The total ATP yield is sometimes cited as 36 ATP because 2 ATP are used for the transport of substances into the mitochondria, thus reducing the net gain to 36 ATP.

  • What is the significance of the script mentioning 'free download' and 'beasiswa program'?

    -The script is promoting educational resources, likely from a collaborating educational platform, offering free downloads and scholarship programs for viewers, encouraging them to visit the website and use a discount code provided.

Outlines

00:00

🔬 Electron Transport Chain and Chemiosmosis

This paragraph delves into the final stage of aerobic respiration, focusing on the electron transport chain and chemiosmosis. It explains the conversion of NADH and FADH2, which are produced in glycolysis, the oxidative decarboxylation, and the Krebs cycle, into ATP. The paragraph clarifies why NADH and FADH2 need to be converted into ATP, as they are forms of energy that the body cannot directly use. The location of these reactions within the mitochondria, specifically the inner mitochondrial membrane, is highlighted. The paragraph also describes the components of the electron transport chain, including protein complexes, coenzyme Q (ubiquinone), cytochrome C, and ATP synthase. The process of electron transfer and the role of oxygen as the final electron acceptor are detailed, culminating in the formation of water and the production of ATP.

05:00

📊 ATP Yield from Aerobic Respiration

The second paragraph discusses the ATP yield from the entire process of aerobic respiration, including glycolysis, oxidative decarboxylation, and the Krebs cycle. It explains the number of ATP molecules produced directly and those generated through the conversion of NADH and FADH2. The paragraph calculates the total ATP production, considering that each NADH molecule can produce three ATPs and each FADH2 molecule can produce two ATPs. It also mentions the reduction of the total ATP count by two due to the energy required to transport substances into the mitochondria. The paragraph concludes with a total of 36 ATPs being produced after accounting for this energy expenditure, and it encourages viewers to download educational resources, participate in scholarship programs, and engage with the educational channel's social media.

Mindmap

Keywords

💡Electron Transport Chain

The Electron Transport Chain (ETC) is a series of protein complexes that transfer electrons from electron donors to electron acceptors via redox reactions. In the context of the video, the ETC is a key process in cellular respiration, occurring in the inner mitochondrial membrane, and is responsible for the production of ATP from NADH and FADH2, which are generated in earlier stages of cellular respiration.

💡Chemiosmosis

Chemiosmosis is the process by which a proton gradient across a membrane is used to drive the synthesis of ATP from ADP and inorganic phosphate. The video explains that chemiosmosis is the mechanism by which ATP is produced in the electron transport chain, as protons flow back into the mitochondrial matrix through ATP synthase, which catalyzes the formation of ATP.

💡Mitochondria

Mitochondria are double-membraned organelles found in eukaryotic cells, known as the 'powerhouses' of the cell because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy. The video emphasizes that the electron transport chain and chemiosmosis, which are crucial for ATP production, occur within the mitochondria.

💡NADH and FADH2

NADH and FADH2 are high-energy electron carriers that are produced during the earlier stages of cellular respiration, such as glycolysis, the citric acid cycle (Krebs cycle), and oxidative phosphorylation. The video discusses how these carriers are essential for the electron transport chain, as they donate electrons to the chain, leading to the production of ATP.

💡ATP Synthase

ATP synthase is a complex enzyme that catalyzes the synthesis of ATP from ADP and inorganic phosphate by utilizing the energy from the flow of protons across a membrane. In the video, ATP synthase is highlighted as a crucial component of the inner mitochondrial membrane, where it uses the proton gradient created by the electron transport chain to produce ATP.

💡Oxidative Phosphorylation

Oxidative phosphorylation is the process of producing ATP using the electron transport chain to supply energy. The video script mentions that oxidative phosphorylation is the stage where the majority of ATP is produced during aerobic respiration, linking the electron transport chain to ATP synthesis.

💡Proton Gradient

A proton gradient is a difference in proton concentration across a membrane, which can be used as a form of potential energy. In the video, the proton gradient is created by the movement of protons (H+) across the inner mitochondrial membrane during the electron transport chain and is a key factor in driving ATP synthesis through chemiosmosis.

💡Citric Acid Cycle

The citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, is a series of chemical reactions used by all aerobic organisms to release stored energy. The video explains that the cycle produces NADH and FADH2, which are then used in the electron transport chain to generate ATP.

💡Glycolysis

Glycolysis is the metabolic pathway that converts glucose into pyruvate, producing a small amount of ATP and NADH. The video mentions glycolysis as the starting point of cellular respiration, which leads to the production of NADH that will be utilized in the electron transport chain.

💡Aerobic Respiration

Aerobic respiration is the process by which cells generate energy in the presence of oxygen, producing ATP. The video script discusses aerobic respiration as a series of processes including glycolysis, the citric acid cycle, and oxidative phosphorylation, which together produce a significant amount of ATP for the cell.

💡Inner Mitochondrial Membrane

The inner mitochondrial membrane is the site of the electron transport chain and ATP synthesis in mitochondria. The video describes how the membrane's structure, including the cristae, provides a large surface area for the proteins involved in these processes, highlighting its importance in cellular energy production.

Highlights

Discussion about electron transport chain and chemiosmosis, the final stage in aerobic respiration.

Electron transport chain and chemiosmosis are processes for producing ATP from NADH and FADH2 generated in glycolysis, oxidative decarboxylation, and the Krebs cycle.

NADH and FADH2 need to be converted into ATP because they are unusable energy forms for the body.

The purpose of the electron transport chain and chemiosmosis is to produce usable energy for the body.

The reactions occur in the inner membrane of the mitochondria, also known as the mitochondrial inner membrane or cristae.

The inner mitochondrial membrane is composed of a phospholipid bilayer, complex proteins, coenzyme Q or ubiquinone, complex III, cytochrome C, and ATP synthase.

The electron transport chain involves the transfer of electrons from one protein to another.

Oxygen acts as the final electron acceptor, combining with hydrogen ions to form water.

The conversion of NADH to ATP starts with NADH being oxidized to NAD+, and electrons are passed through complex proteins.

For each NADH, three ATP molecules are produced through a series of electron transfers and proton movements.

The conversion of FADH2 to ATP involves FADH2 being oxidized to FAD+, and electrons are transferred to complex proteins.

For each FADH2, two ATP molecules are produced due to the electron transfer and associated proton gradient.

The total ATP yield from aerobic respiration is calculated by considering the ATP produced in glycolysis, oxidative decarboxylation, and the Krebs cycle.

Glycolysis produces 2 ATP and 2 NADH, oxidative decarboxylation produces 2 NADH, and the Krebs cycle produces 6 NADH, 2 FADH2, and 2 ATP.

The total ATP yield is often cited as 36 ATP because 2 ATP are used for transport into the mitochondria.

The video provides a detailed explanation of the electron transport chain and chemiosmosis, making complex biological processes understandable.

The video encourages viewers to download educational content and take advantage of scholarship programs offered by schools.

The video concludes with a call to action for viewers to subscribe to the channel and follow social media accounts for more educational content.

Transcripts

play00:00

Hai Hari ini kita akan membahas tentang

play00:08

rantai transpor elektron dan kimia

play00:10

osmosis yang merupakan Tahap terakhir

play00:12

dalam respirasi aerob nah di tahap

play00:15

Inilah kita sebenarnya akan membuat

play00:17

sebagian besar ATP kita rantai transpor

play00:20

elektron dan chemiosmosis merupakan

play00:22

proses produksi ATP dari NADH dan fadh2

play00:25

yang dihasilkan dalam Riko lisis

play00:28

dekarboksilasi oksidatif dan siklus Kreb

play00:31

Kenapa nadh2 fadh2 ini harus diubah

play00:34

menjadi ATP karena nadh2 fadh2 merupakan

play00:38

salah satu bentuk energi namun berupa

play00:40

energi yang belum dapat digunakan oleh

play00:42

tubuh sehingga harus diubah menjadi ATP

play00:45

agar dapat dimanfaatkan oleh tubuh

play00:47

sehingga tujuan dari rantai transpor

play00:50

elektron dan chemiosmosis adalah untuk

play00:52

menghasilkan energi yang dapat

play00:54

dimanfaatkan oleh tubuh yang harus

play00:56

pertama kita ketahui adalah dimana kedua

play00:59

reaksi ini terjadi

play01:00

Ayo kita telah sungguh di video

play01:02

sebelumnya bahwa tahap ini terjadinya di

play01:04

bagian mitokondria nah mitokondria

play01:07

sendiri tersusun atas beberapa bagian

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meliputi membran luar membran dalam dan

play01:13

matriks mitokondria kedua tahapan ini

play01:16

berlangsung pada mitokondria tepatnya

play01:18

pada bagian membran dalam mitokondria

play01:21

atau yang disebut dengan kristal bentuk

play01:24

membran dalam mitokondria jika

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diperbesar akan menjadi seperti gambar

play01:28

berikut bagian membran dalam mitokondria

play01:31

tersusun atas fosfolipid bilayer

play01:33

Kompleks protein 1 koenzim Q atau

play01:37

ubiquinone Kompleks suatu IM3 Kompleks

play01:40

protein 4 sitokrom C ATP synthase dan

play01:44

kompleks protein dua yang terletak di

play01:47

bagian sini disebut dengan rantai

play01:49

transpor elektron karena dalam prosesnya

play01:51

terjadi transfer elektron dari satu

play01:53

protein ke protein yang lain dalam

play01:56

transfer elektron ini oksigen akan

play01:59

berperan sebagai pendiri

play02:00

elektron terakhir yang akan membentuk

play02:02

H2O yang nantinya H2O ini akan

play02:05

dikeluarkan dari sel perubahan n Adha

play02:08

dan fadh2 menjadi ATP terdapat sedikit

play02:11

perbedaan dari prosesnya Bagaimanakah

play02:14

perbedaannya Yuk kita simak lebih lanjut

play02:16

yang pertama pengubahan ennard menjadi

play02:19

ATP terlebih dahulu prosesnya terjadi

play02:22

pada tahap transpor elektron diawali

play02:24

dari ennard akan diuraikan menjadi

play02:26

ennard plus yang membuat elektron hasil

play02:29

dari reaksi ini akan masuk ke kompleks

play02:32

protein satu kemudian dikirim ke

play02:35

ubiquinone saat elektron melewati

play02:38

Kompleks protein satu hal ini akan

play02:40

memicu dipompanya H plus keluar menuju

play02:43

ruang antar membran elektron dari

play02:46

ubiquinone dibawa melewati Kompleks

play02:48

protein tiga ke sitokrom c saat melewati

play02:52

Kompleks protein tiga hal ini juga akan

play02:54

memicu dipompanya H plus keluar menuju

play02:57

ruang antar membran Kemudian dari

play02:59

sitokrom C

play03:00

fashion akan dibawa ke matriks

play03:02

mitokondria melalui Kompleks protein 4

play03:04

saat elektron melewati Kompleks protein

play03:07

4 akan mengeluarkan 1 atom hidrogen lagi

play03:10

menuju ruang antar membran Nah

play03:12

selanjutnya yakin kemudian akan diterima

play03:15

oleh molekul Oksigen yang kemudian akan

play03:17

berikatan dengan dua ion H + membentuk

play03:20

H2O tidak dihitung transfer elektron

play03:24

dari bermacam-macam protein tadi memicu

play03:26

dipompanya 3 plus keluar menuju ruang

play03:28

antar membran hapless atau Proton

play03:31

tersebut akan Kembali menuju matriks

play03:33

mitokondria melalui enzim yang disebut

play03:36

ATP synthase lewatnya H plus pada ATP

play03:39

synthase akan memicu engine tersebut

play03:41

membentuk ATP secara bersamaan karena

play03:45

terdapat tiga H + yang masuk kembali

play03:47

kedalam matriks maka terbentuklah tiga

play03:50

molekul ATP pada akhirnya untuk setiap

play03:53

satu ennard menghasilkan tiga ATP

play03:57

selanjutnya pengubahan fadh2

play04:00

dia TP pertama fadh2 diuraikan menjadi

play04:04

evade plus kemudian elektron masuk ke

play04:07

kompleks protein 2 transfer pada

play04:10

Kompleks protein 2 tidak memicu

play04:12

dipompanya H plus keluar menuju ruang

play04:14

antar membran Setelah dari Kompleks

play04:17

protein 2 elektron akan ditangkap oleh

play04:19

ubiquinone dari ubiquinone elektron akan

play04:22

dibawa melewati Kompleks protein tiga ke

play04:25

sitokrom c saat melewati Kompleks

play04:27

protein tiga akan dikeluarkan satu ion

play04:30

hidrogen berikutnya elektron dari

play04:32

sitokrom C akan dibawa ke matriks

play04:35

mitokondria melalui Kompleks protein 4

play04:37

pada saat melewati Kompleks protein 4

play04:40

akan dikeluarkan juga satu atom hidrogen

play04:42

Nah selanjutnya elektron kemudian akan

play04:45

diterima oleh molekul Oksigen yang

play04:47

kemudian berikatan dengan dua ion H +

play04:50

membentuk H2O setiap atom hidrogen yang

play04:53

terbentuk akan masuk ke ATP synthase

play04:55

untuk menjadi ATP jumlah ion hidrogen

play04:58

yang dikeluarkan berjumlah 2

play05:00

untuk setiap satu molekul fadh2 jadi

play05:04

hasil dari perubahan untuk setiap satu

play05:06

fadh2 menghasilkan 2atp nah proses

play05:11

transfer elektron terjadi sampai tahap

play05:13

diterimanya elektron oleh Oksigen yang

play05:16

merupakan aseptor elektron terakhir

play05:18

sedangkan proses pembentukan ATP oleh

play05:21

enzim ATP synthase tersebut dinamakan

play05:24

dengan chemiosmosis nah selesailah

play05:27

proses respirasi aerob selanjutnya

play05:30

berapakah total yang dihasilkan dalam

play05:32

respirasi aerob pada proses glikolisis

play05:35

dihasilkan 2 ATP dan 2 nadh2 pada proses

play05:39

dekarboksilasi oksidatif dihasilkan

play05:41

2nadh pada siklus Krebs dihasilkan 6

play05:44

nadh2 fadh2 dan 2atp lalu Bagaimana

play05:49

menjumlahkannya kita tahu kalau ATP

play05:53

langsung menjadi ATP tidak perlu

play05:54

diubahnya lalu untuk ennard dikalikan

play05:57

dengan tiga dan fadh2 di

play06:00

en2 sehingga pada glikolisis ini

play06:02

dihasilkan 2atp 2N Adha diubah menjadi

play06:07

enam ATP pada dekarboksilasi oksidatif

play06:10

dua ayat Adha menjadi enam ATP Pada

play06:14

siklus Krebs ennard menjadi 18 allpcb

play06:18

fadh2 menjadi empat ATP dan 2 ATP tetap

play06:24

menjadi dua ATP sehingga totalnya 38 ATP

play06:29

Lalu kenapa ada yang menyebutkan

play06:31

totalnya 36 ATP karena 2 ATP digunakan

play06:35

untuk menembus mitokondria karena kita

play06:38

tahu ya kalau misalkan glikolisis

play06:40

terjadinya di sitosol dan reaksi yang

play06:42

lainnya terjadinya di mitokondria

play06:43

sehingga butuh energi untuk menembus

play06:46

mitokondria pada akhirnya totalnya 38

play06:51

ATP dikurangi 2 ATP menjadi 36 ATP nah

play06:57

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play07:00

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関連タグ
Aerobic RespirationElectron TransportChemiosmosisATP ProductionMitochondriaNADHFADH2Cellular EnergyBiological ProcessEducational Video
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