BIOLOGI Kelas 11 - Sistem Peredaran Darah (PART 1) | GIA Academy

GIA Academy
23 Oct 202016:05

Summary

TLDRThis educational video script from GYA Academy YouTube channel explains blood components and blood types. It covers the composition of blood, including plasma and blood cells, and their functions. The script delves into the importance of blood type compatibility in transfusions to prevent blood clotting. It also introduces the ABO blood group system, explaining the presence of antigens and antibodies in different blood types. The video concludes with quizzes to test viewers' understanding of blood components and the implications of blood type mismatches.

Takeaways

  • 🩸 Blood transfusions require matching blood types to prevent blood clotting.
  • 🧬 Blood consists of plasma (50%) and blood cells (45%), with plasma being 90% water and the rest dissolved substances like proteins and salts.
  • 🔬 Plasma contains various proteins with different functions, such as Albumin for water balance and Fibrinogen for blood clotting.
  • 🌐 Blood cells include Red Blood Cells (Erythrocytes), White Blood Cells (Leukocytes), and Platelets (Thrombocytes).
  • ❤️ Red Blood Cells contain Hemoglobin, which binds to oxygen and carbon dioxide, and have a lifespan of about 120 days.
  • 🔵 White Blood Cells are divided into Granulocytes (Neutrophils, Eosinophils, Basophils) and Agranulocytes (Lymphocytes, Monocytes), playing key roles in immune response.
  • 🆘 Basophils are involved in allergic reactions, Eosinophils defend against parasites, and Neutrophils destroy bacteria and foreign substances.
  • 🔄 Lymphocytes produce antibodies, and Monocytes can develop into macrophages to engulf pathogens.
  • 🩲 Platelets are essential for blood clotting and are produced by megakaryocytes, with a lifespan of about 10-12 days.
  • 🔄 The ABO blood group system classifies blood into four types: A, B, AB, and O, based on the presence of antigens and antibodies in the blood.
  • ⚠️ Blood type O is known as the universal donor because it lacks antigens, and blood type AB is known as the universal recipient because it lacks antibodies.

Q & A

  • What is the primary reason for blood transfusions?

    -Blood transfusions are primarily done when someone has lost a significant amount of blood.

  • What must be considered during blood transfusions to prevent blood clotting?

    -The blood types of both the donor and the recipient must be compatible to prevent blood clotting.

  • What are the components involved in blood clotting?

    -Components involved in blood clotting include thrombocytes (platelets), fibrinogen, and various clotting factors.

  • What are the main components that make up human blood?

    -Human blood is composed of approximately 50% plasma and 45% blood cells.

  • What is the function of plasma in the blood?

    -Plasma functions to dissolve other substances such as proteins, salts, nutrients, hormones, carbon dioxide, and nitrogenous waste.

  • What are the types of proteins found in plasma and their functions?

    -Proteins in plasma include Albumin for maintaining fluid balance, Globulins for forming antibodies, Fibrinogen for blood clotting, and others like Presipitin, Antitoxin, and Optimisin with various immune functions.

  • How long is the lifespan of red blood cells (erythrocytes)?

    -Red blood cells have a lifespan of about 120 days.

  • What is hemoglobin and what role does it play?

    -Hemoglobin is a complex molecule made of protein globin and iron-containing molecules that bind oxygen and carbon dioxide.

  • What are the different types of white blood cells (leukocytes) and their functions?

    -Types include Neutrophils for destroying bacteria, Eosinophils for fighting parasites, Basophils for allergic reactions, Lymphocytes for antibody production, and Monocytes for engulfing pathogens.

  • What is the role of platelets (thrombocytes) in the blood?

    -Platelets play a crucial role in the blood clotting process to prevent bleeding when blood vessels are damaged.

  • Why is blood type O considered the universal donor, and type AB the universal recipient?

    -Type O is a universal donor because it lacks antigens, and type AB is a universal recipient because it lacks antibodies, allowing them to receive blood from any blood type.

  • What is the ABO blood group system and its significance in blood transfusions?

    -The ABO blood group system classifies blood into four types (A, B, AB, O) based on the presence of antigens (aglutinogens) and antibodies (aglutinins) in red blood cells and plasma, which is crucial to prevent blood transfusion reactions.

Outlines

00:00

🩸 Blood Transfusion Process and Blood Components

The script introduces the topic of blood transfusions, emphasizing the importance of matching blood types to avoid clotting. It explains the composition of blood, which includes plasma (50%) and blood cells (45%), with plasma consisting of 90% water and various dissolved substances like proteins, salts, nutrients, hormones, carbon dioxide, and nitrogenous waste. The video also discusses the different types of proteins in plasma, such as Albumin, Globulin, and others, each with specific functions like maintaining water balance, forming antibodies, and aiding in blood clotting. The script further delves into the components of blood cells, including red blood cells (erythrocytes), which lack a nucleus and contain hemoglobin for oxygen transport, and their lifespan of about 120 days.

05:00

🔬 White Blood Cells and Platelets

This section focuses on white blood cells (leukocytes), which have a nucleus and can live for months. They are crucial for the immune system and can move through blood vessel walls. Leukocytes are categorized into granulocytes (neutrophils, eosinophils, and basophils) and agranulocytes (lymphocytes and monocytes). Each type has specific functions, such as fighting bacteria, allergic reactions, and producing antibodies. The script also covers platelets (thrombocytes), which are smaller than other blood cells, lack a nucleus, and play a vital role in blood clotting. Platelets have a short lifespan of 10-12 days and are involved in the止血 process when there is an injury.

10:02

🏥 Blood Types and Compatibility

The script explains the ABO blood group system, discovered by Karl Landsteiner, which classifies blood into four types based on the presence of antigens (A and B) and antibodies (anti-A and anti-B) in red blood cells and plasma. Type A blood has antigen A, type B has antigen B, type AB has both, and type O has neither. The plasma of type A blood contains anti-B, type B contains anti-A, type AB contains neither, and type O contains both. This blood group system is critical for safe blood transfusions, with type O being the universal donor and type AB being the universal recipient. The script also includes a quiz to test understanding of blood components and compatibility.

15:03

📚 Recap and Conclusion

The final paragraph summarizes the discussion on blood components, including plasma and blood cells, and the ABO blood group system with its antigens and antibodies. It highlights the importance of blood compatibility to prevent blood clotting during transfusions. The script encourages viewers to continue learning about blood and its components and to stay tuned for more educational videos on the channel.

Mindmap

Keywords

💡Transfusion

Transfusion refers to the process of transferring blood or blood components from one person to another, or from a donor to a patient. In the video, this process is discussed in the context of replacing blood lost by an individual. The script mentions that certain conditions must be met during transfusion, such as matching blood types to prevent blood clotting in the recipient's body.

💡Blood Clotting

Blood clotting is the process by which blood changes from a liquid to a gel, forming a clot to prevent excessive bleeding when there is an injury. The video script explains that blood components play a role in clotting and that mismatched blood types can cause clotting, which is undesirable during a transfusion.

💡Blood Components

Blood components refer to the parts that make up the blood, including plasma, red blood cells, white blood cells, and platelets. The script provides a detailed composition of human blood, stating that it is about 50% plasma and 45% blood cells. Understanding these components is crucial for the video's theme of blood transfusion and compatibility.

💡Plasma

Plasma is the liquid component of blood in which blood cells are suspended. It is composed mainly of water, proteins, electrolytes, nutrients, hormones, and waste products. In the video, plasma's role is highlighted as it carries nutrients and waste, and its composition is vital for maintaining blood volume and regulating body functions.

💡Red Blood Cells (Erythrocytes)

Red blood cells, or erythrocytes, are the most abundant cells in the blood and are responsible for carrying oxygen to the body's tissues. The video mentions that they contain hemoglobin, which gives them their red color and oxygen-carrying capacity. The lifespan of erythrocytes is also discussed, as well as their count in the blood.

💡White Blood Cells (Leukocytes)

White blood cells, or leukocytes, are a crucial part of the immune system and are involved in protecting the body against both infectious disease and foreign materials. The script describes different types of leukocytes, such as neutrophils, eosinophils, basophils, lymphocytes, and monocytes, and their roles in the immune response.

💡Platelets (Thrombocytes)

Platelets are cell fragments that play a key role in blood clotting to stop bleeding at the site of vascular injury. The video script explains that they are produced by megakaryocytes and are essential for the hemostasis process, which prevents excessive bleeding when blood vessels are damaged.

💡Hemoglobin

Hemoglobin is an iron-containing molecule in red blood cells that binds to oxygen and carries it to the body's tissues. The video emphasizes its importance in the function of erythrocytes and mentions that it is a complex molecule made up of protein globin and iron-containing heme groups.

💡Blood Type

Blood type refers to the classification of blood based on the presence or absence of specific antigens on the surface of red blood cells and the corresponding antibodies in the plasma. The video script discusses the ABO blood group system, which includes types A, B, AB, and O, and explains how these types are crucial for safe blood transfusions.

💡Antigens

Antigens are substances that can trigger an immune response, such as the production of antibodies, in the body. In the context of the video, antigens are the aglutinogens found on red blood cells that can cause a reaction if they are incompatible with the antibodies (aglutinins) in the recipient's plasma during a transfusion.

💡Universal Donor

A universal donor is a person whose blood can be safely donated to individuals of any blood type without causing an adverse reaction. The video script specifies that type O blood is considered the universal donor because it lacks A and B antigens on the red blood cells, making it safe to give to recipients of any blood type.

Highlights

Introduction to the process of blood transfusion and its importance.

Explanation of why blood transfusions require compatible blood types to prevent blood clotting.

Description of the components involved in blood clotting.

Overview of the composition of human blood, including plasma and blood cells.

Detailed composition of plasma, including water, proteins, salts, nutrients, hormones, and waste products.

Function of proteins in plasma, such as Albumin, Globulin, Fibrinogen, and others.

Role of salts and ions in maintaining osmotic pressure, pH, and cellular functions.

Explanation of the role of carbon dioxide in the blood.

Introduction to blood cells, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).

Characteristics of red blood cells, including their shape, lifespan, and function in oxygen transport.

Description of white blood cells, their types, and their immune functions.

Functions of platelets in blood clotting and wound healing.

Explanation of the ABO blood group system and its significance in blood transfusions.

Importance of compatible blood types in transfusions to avoid adverse reactions.

Concept of universal donors and recipients in blood transfusions.

Discussion on the potential issues with blood transfusions outside the ABO system.

Interactive quiz to test understanding of blood components and their characteristics.

Summary of the video's discussion on blood components and blood groups.

Transcripts

play00:00

Hai Cinta

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[Musik]

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hai hai teman teman selamat datang

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kembali di GYA Academy youtube channel

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Semoga teman-teman selalu sehat dan

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terus semangat Oh iya teman-teman pernah

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melihat proses berikut nah Gambar ini

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menunjukkan proses transfusi darah yang

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dilakukan ketika seseorang kehilangan

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banyak darah proses transfusi darah

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harus memperhatikan syarat-syarat

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tertentu salah satunya pendonor dan

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resipien harus memiliki golongan darah

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yang sesuai hal tersebut bertujuan untuk

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menghindari terjadinya penggumpalan

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darah di tubuh resipien mengapa dapat

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terjadi penggumpalan darah komponen apa

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yang berperan dalam penggumpalan darah

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Apa saja komponen yang menyusun darah

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untuk menjawab pertanyaan tersebut yuk

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simak video ini sampai selesai kita akan

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belajar

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tentang komposisi dan golongan darah

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Tahukah kamu volume darah manusia

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berjumlah kurang lebih Delapan persen

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dari total berat badan manusia yaitu

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sekitar 4,5 sampai 5,5 liter darah pada

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tubuh kita tersusun atas 50% plasma

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darah dan 45 persen sel-sel darah nah

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volume darah yang banyak itu terdiri

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dari apa aja ya kita bahas satu per satu

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komponen penyusun darah manusia pertama

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plasma darah plasma darah pada tubuh

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kita tersusun atas 90% air dan sepuluh

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persen sisanya berupa zat-zat yang

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terlarut di dalamnya seperti protein

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garam garam atau ion nutrisi hormon

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karbondioksida Dan Sampah nitrogen air

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pada plasma

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nah digunakan untuk melarutkan zat-zat

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lain selanjutnya ada nutrisi seperti

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glukosa asam amino dan asam lemak

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nutrisi ini berguna untuk cadangan

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makanan di dalam sel dan molekulnya

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dapat diuraikan lagi berikutnya protein

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ada beberapa jenis protein yang ada di

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dalam plasma darah dengan fungsi yang

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beragam ada Albumin untuk mempertahankan

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keseimbangan air dalam darah dan

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jaringan serta dapat mengatur volume

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darah kemudian globulin untuk membentuk

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antibodi yang berguna untuk kekebalan

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tubuh fibrinogen berperan dalam proses

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penggumpalan darah licin menghancurkan

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atau memecah antigen presipitin untuk

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mengendapkan antigen antitoksin untuk

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menetralkan racun dan optimis in untuk

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memacu sifat fagosit pada leukosit

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komponen dalam plasma darah selanjutnya

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adalah garam-garam

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atau ion seperti natrium kalium kalsium

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magnesium klorida dan bikarbonat yang

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berguna untuk menyeimbangkan tekanan

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osmosis mempertahankan ph atau buffer

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fungsi saraf dan otot serta mengatur

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permeabilitas membran sel ada

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karbondioksida yang merupakan hasil

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respirasi sel dan dibawa ke paru-paru

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untuk dibuang kemudian hormon yang akan

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mempengaruhi aktivitas organ yang dituju

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Dan Sampah nitrogen sebagai hasil

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metabolisme yang akan diekskresikan ke

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ginjal selain plasma darah darah juga

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mengandung sel-sel darah pastinya

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teman-teman tahu kan ada saudara apa

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saja pertama ada sel darah merah atau

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eritrosit berikutnya ada sel darah putih

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atau leukosit dan ada keping darah atau

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trombosit

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Ayo kita bahas lebih lanjut pertama sel

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darah merah eritrosit eritrosit dalam

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tubuh kita jumlahnya sangat banyak

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mencapai 99% dari total darah eritrosit

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berbentuk bikonkaf tidak mempunyai inti

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sel sehingga tidak dapat hidup dalam

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waktu yang lama eritrosit berwarna merah

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karena mengandung hemoglobin Tahukah

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kamu apa itu hemoglobin hemoglobin

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merupakan molekul kompleks dari protein

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globin dan molekul besi hemin yang

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berperan dalam pengikatan oksigen dan

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karbondioksida nah eritrosit ini hanya

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berumur sekitar 120 hari eritrosit yang

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telah mati akan dirombak di hati menjadi

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bilirubin dan biliverdin atau zat warna

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empedu zat besi hasil perombakan

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tersebut kemudian dikirim ke hati dan

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limpa untuk digunakan dalam pembentukan

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eritrosit baru tiap satu mm3 darah

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laki-laki mengandung 5000000 saudara

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merah sedangkan perempuan memiliki

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kurang lebih empat juta sel darah merah

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per milimeter kubik kemudian ada sel

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darah putih leukosit leukosit memiliki

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inti sel sehingga dapat bertahan hidup

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berbulan-bulan tidak punya hemoglobin

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sehingga tidak berwarna merah dapat

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bergerak ameboid artinya gerakan

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sitoplasmanya memanjang sehingga Sel

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akan bergerak perlahan leukosit

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berbentuk tidak tetap dan dapat menembus

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dinding pembuluh darah leukosit ini

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diproduksi disusun merah limpa dan

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kelenjar getah bening jumlah leukosit

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sekitar 7.000 shelper mm3 darah

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[Musik]

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berdasarkan karakteristik sitoplasmanya

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sel darah putih dibagi menjadi dua

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kelompok ada granulosit merupakan sel

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darah putih yang sitoplasmanya

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bergranula John

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nya neutrofil eosinofil dan basofil dan

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ada agranulosit merupakan saudara putih

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yang sitoplasmanya tidak bergranula

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seperti limfosit dan monosit sekarang

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kita lihat satu persatu karakteristik

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leukosit bergranula pertama basofil

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jumlahnya 20-50 butir tiap satu mm3

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darah plasmanya bersifat basa dan

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terdapat bintik-bintik biru yang

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mengandung histamin fungsinya memberi

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reaksi alergi dengan mengeluarkan

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histamin yang mengakibatkan peradangan

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dan heparin yang berperan dalam

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pembekuan darah basofil ini bersifat

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fagosit artinya soalnya dapat menelan

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material padat didalam tubuh berikutnya

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eosinofil berjumlah 100-400 butir tiap

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mm3 darah plasmanya bersifat asam dan

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terdapat bintik-bintik merah berperan

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dalam pertahanan

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terhadap parasit eosinofil juga bersifat

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fagosit leukosit granulosit selanjutnya

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neutrofil berjumlah 3000 sampai 7000

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butir tiap mm3 darah plasmanya bersifat

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netral dan terdapat bintik-bintik merah

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kebiruan berperan dalam memusnahkan

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bakteri dan zat asing yang masuk ke

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tubuh serta bersifat fagosit dan

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karakteristik leukosit tidak bergerak

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nulla antara lain pertama limfosit

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berjumlah 1000 500-3 ribu butir tiap mm3

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darah tidak dapat bergerak bebas tetapi

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dapat membentuk zat antibodi berperan

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dalam pertahanan terhadap serangan

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mikroorganisme makromolekul asing dan

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sel-sel kanker selanjutnya ada monosit

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berjumlah 100 sampai 700 butir tiap mm3

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darah dapat bergerak cepat bersifat

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fagosit dapat bergerak bebas membesar

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dan berkembang menjadi makrofag berperan

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menjaga kekebalan tubuh dan infeksi nah

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leukosit memiliki fungsi yang sangat

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penting bagi tubuh kita diantaranya

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adalah pertama menghancurkan kuman

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penyakit dan zat-zat asing Seperti bahan

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kimia berbahaya kedua mengangkut lemak

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dan menghasilkan histamin dan terakhir

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dapat melumpuhkan kuman penyakit yang

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berada diluar darah keren banget ya

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teman-teman leukosit dapat membantu kamu

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agar tidak mudah sakit Sel darah yang

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terakhir yang akan kita bahas adalah

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keping darah atau trombosit trombosit

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dihasilkan oleh sel megakaryocyte

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berukuran lebih kecil dibandingkan sel

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darah lainnya tidak memiliki inti

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sehingga trombosit berumur pendek hanya

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sekitar 10-12 hari dan bentuknya tidak

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beraturan

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Hai trombosit tidak memiliki warna atau

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bening jumlahnya sekitar 200.000 sampai

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400 ribu tiap mm3 darah terakhir

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trombosit berperan penting dalam proses

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pembekuan darah saat terjadi luka atau

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cedera pembuluh darah kita bisa rusak

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dan dapat menyebabkan pendarahan

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akibatnya tubuh kita akan mengaktifkan

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serangkaian proses pembekuan darah atau

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hemostasis ketika terjadi luka dan darah

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keluar maka trombosit pecah dan

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mengeluarkan enzim trombokinase yang

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merupakan zat antihemofilia enzim

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trombokinase akan menghasilkan

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protrombin selanjutnya protrombin dengan

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bantuan ion kalsium dan vitamin K akan

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berubah menjadi trombin dan trombin akan

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mengubah fibrinogen menjadi

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benang-benang fibrin akhirnya darah yang

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keluar dapat dibendung dengan cara

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membekukan sel darah pada bagian yang

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luka

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Hai nah teman-teman meskipun semua jenis

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darah tampak sama tetapi kandungan

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proteinnya sangat beragam Apabila ada

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Protein asing yang tidak sesuai masuk ke

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tubuh kita maka tubuh akan menyerang

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dengan cara penggumpalan atau aglutinasi

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Protein asing ini disebut juga dengan

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antigen atau aglutinogen yang terdapat

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di dalam eritrosit didalam tubuh kita

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juga terdapat zat penolak antigen yang

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disebut antibodi atau aglutinin yang

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terdapat di dalam plasma darah karena

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penting dan uniknya komposisi darah ini

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pada tahun 1900 careless Steiner seorang

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ahli patologi melakukan penelitian dan

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berhasil menemukan perbedaan aglutinogen

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dan aglutinin yang terkandung dalam

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darah manusia sehingga dikemukakan

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sistem darah Abo yang membedakan darah

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menjadi empat golongan pertama gol

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udara a-dha rahyang eritrositnya

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mengandung aglutinogen a sedangkan

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plasma darahnya mengandung aglutinin

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beta atau anti-b kedua golongan darah B

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darah yang eritrositnya mengandung

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aglutinogen B sedangkan plasma darahnya

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mengandung aglutinin Alfa atau antia

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ketiga golongan darah AB darah yang

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eritrositnya mengandung aglutinogen a

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dan b sedangkan plasma darahnya tidak

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mengandung aglutinin terakhir golongan

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darah O darah yang eritrositnya tidak

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mengandung aglutinogen sedangkan plasma

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darahnya mengandung aglutinin Alfa dan

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Beta penggolongan darah Abo ini sangat

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berperan dalam transfusi darah antara

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resipien dan pendonor resipien adalah

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orang yang menerima darah donor adalah

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orang yang memberikan darahnya Dalam

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transfusi darah harus diperhatikan jenis

play12:05

aglutinogen Dono

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dan aglutinin recipe and kamu harus tahu

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kalau golongan darah O disebut donor

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universal karena tidak memiliki antigen

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sehingga mampu memberikan darah ke semua

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golongan darah dan golongan darah AB

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disebut resipien universal karena tidak

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memiliki antibodi sehingga dapat

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menerima darah dari golongan darah

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manapun tapi pada praktiknya hal

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tersebut jarang dilakukan karena

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kemungkinan adanya ketidakcocokan darah

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di luar sistem ABO gimana sampai di sini

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kamu bisa kan memahami tentang komponen

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darah dan golongan darah Nah agar kamu

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lebih paham kita coba selesaikan

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soal-soal berikut

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Hai soal pertama menanyakan komponen sel

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darah yang sesuai dengan ciri-ciri yang

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disebutkan yaitu memiliki inti sel

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bentuknya tidak tetap dan sitoplasmanya

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terdapat granula Ayo menurut kamu

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jawabannya apa Oke kita ingat lagi semua

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cerita di merupakan ciri sel darah putih

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atau leukosit perlu kita perhatikan ciri

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yang ketiga sitoplasmanya bergranula nah

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leukosit granulosit adalah neutrofil

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eosinofil dan basofil sedangkan leukosit

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tidak bergerak nulla adalah limfosit dan

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monosit jadi jawaban yang benar adalah a

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soal kedua menanyakan alasan mengapa

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orang yang bergolongan darah A tidak

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bisa mendonorkan darah kepada orang

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bergolongan darah B nah Mari kita ingat

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lagi tentang aglutinogen dan aglutinin

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yang terkandung didalam sel darah

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golongan darah A eritrositnya

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Hai aglutinogen a sedangkan plasma

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darahnya mengandung aglutinin beta atau

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anti-b dan golongan darah B eritrositnya

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mengandung aglutinogen B sedangkan

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plasma darahnya mengandung aglutinin

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Alfa atau antia sehingga jika darah

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bergolongan darah A dan B bertemu maka

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aglutinogen a akan bertemu dengan

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aglutinin Alfa dan aglutinogen B akan

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bertemu dengan aglutinin beta maka

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jawaban yang benar adalah B soal

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terakhir kita diminta menganalisis

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pernyataan yang benar tentang leukosit

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Masih ingatkah kamu berapa jumlah normal

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leukosit di dalam darah jumlah leukosit

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normal sekitar 7.000 self er mm3 darah

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jika kadar leukosit rendah maka tubuh

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akan rentan terserang penyakit karena

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kurangnya pertahanan tubuh dan jika

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terlalu tinggi keadaan ini disebut

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leukemia yang akan menyebabkan tubuh

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mengalami

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ia berat karena leukosit berkembang

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dengan cepat sehingga sedikit ruang yang

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tersisa untuk eritrosit normal

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berkembang jadi jawaban yang tepat

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adalah c lekosit yang berlebih dari

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keadaan normal akan menyebabkan tubuh

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mengalami anemia

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[Musik]

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Hai Oke teman-teman jadi di video kali

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ini kita sudah membahas tentang komponen

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darah yang terdiri dari plasma darah dan

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sel-sel darah kemudian golongan darah

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yang dapat dibedakan menjadi golongan

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darah A B AB dan O yang memiliki

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aglutinogen dan aglutinin nya

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masing-masing jadi ketika aglutinogen

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tidak cocok dengan aglutininnya maka

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akan terjadi penggumpalan darah sekarang

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Kamu jadi tahu apa yang menyebabkan

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darah kita dapat menggumpal nah sampai

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disini dulu pembahasan kita tentang

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komponen dan golongan darah jangan lupa

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tonton terus video-video terbaru di

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channel kita ya sampai jumpa di video

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berikutnya

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[Musik]

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hai hai

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