Gastrulação: Ectoderma, Mesoderma e Endoderma - Terceira Semana do Desenvolvimento (Embriologia)

Bio Aulas - Prof. Matheus Moura
15 Dec 201809:14

Summary

TLDRThis educational video script discusses the third week of embryonic development, focusing on gastrulation. It explains how the bilaminar embryonic disc transforms into a trilaminar disc, establishing the three germ layers: ectoderm, mesoderm, and endoderm. The gastrulation process is described, starting with the formation of the primitive streak from epiblast cells that migrate and invaginate to form the endoderm and mesoderm, with the remaining epiblast becoming the ectoderm. The script includes a visual aid to illustrate the process, aiming to clarify this crucial stage in embryonic development.

Takeaways

  • 📅 The script discusses the third week of embryonic development, focusing on key events that occur during this period.
  • 🌱 Gastrulation is introduced as the process that establishes the three germ layers in the embryo: ectoderm, mesoderm, and endoderm.
  • 🔄 The gastrulation process begins with the formation of the primitive streak on the surface of the epiblast, where cells proliferate and migrate towards the embryo's median plane.
  • 📍 The primitive streak grows from the caudal region towards the cephalic region, stopping at the primitive node.
  • 🔍 Cells from the epiblast invaginate, or sink inwards, towards the hypoblast, which will eventually be replaced by the endoderm.
  • 🔄 Some cells that migrate to the hypoblast replace it, forming the endoderm, while others concentrate in the middle to form a new layer called the mesoderm.
  • 🌟 The remaining epiblast becomes the ectoderm, completing the formation of the trilaminar embryonic disc with ectoderm, mesoderm, and endoderm layers.
  • 🧬 These germ layers are crucial as they give rise to all tissues and organs of the embryo.
  • 📹 The script includes a visual demonstration of the gastrulation process, showing cells invaginating and forming the different germ layers.
  • 🔑 The video script ends with a golden key takeaway, emphasizing the importance of understanding the gastrulation process in embryonic development.
  • 👋 The presenter invites viewers to join the next video lesson, indicating a series of educational content on embryonic development.

Q & A

  • What is the main topic of the video lesson?

    -The main topic of the video lesson is the third week of embryonic development, specifically focusing on the process of gastrulation.

  • What significant transformation occurs during the third week of embryonic development?

    -During the third week, the bilaminar embryonic disc transforms into a trilaminar disc, forming the three germ layers: ectoderm, mesoderm, and endoderm.

  • What is gastrulation?

    -Gastrulation is the process that establishes the three germ layers (ectoderm, mesoderm, and endoderm) in the embryo, which will give rise to all tissues and organs.

  • What are the two membranes that appear in the epiblast at the end of the second week?

    -The two membranes are the precordal plate, indicating the cephalic (head) region, and the cloacal membrane, indicating the caudal (tail) region.

  • How does the primitive streak form?

    -The primitive streak forms when cells from the epiblast proliferate and migrate toward the midline, creating a visible line on the surface of the epiblast.

  • In which direction does the primitive streak grow?

    -The primitive streak grows from the caudal (tail) region towards the cephalic (head) region.

  • What happens to the cells of the epiblast during gastrulation?

    -During gastrulation, epiblast cells proliferate, migrate to the primitive streak, invaginate, and move toward the hypoblast, forming new germ layers.

  • What is the primitive groove?

    -The primitive groove is an indentation formed by the invagination of epiblast cells at the primitive streak.

  • What happens to the hypoblast during gastrulation?

    -During gastrulation, some invaginating epiblast cells displace the hypoblast cells, forming the endoderm.

  • What are the three germ layers formed by the end of gastrulation?

    -The three germ layers formed are the ectoderm, mesoderm, and endoderm.

  • What role does the epiblast play in gastrulation?

    -The epiblast plays a crucial role by contributing cells that form the primitive streak and subsequently differentiate into the three germ layers.

  • How can one visualize the process of gastrulation?

    -The process of gastrulation can be visualized through diagrams and animations that show the movement and differentiation of cells within the embryo.

Outlines

00:00

🌟 Introduction to the Third Week of Embryonic Development

The script introduces the third week of embryonic development, focusing on significant events that occur during this period. The main topic of this section is gastrulation, a process that establishes the three germ layers in the embryo: ectoderm, mesoderm, and endoderm. The video-lesson will cover each event in detail, starting with gastrulation. It explains the transformation of the bilaminar embryonic disc into a trilaminar one, where the cells of the epiblast proliferate and migrate towards the midline to form the primitive streak, which is essential for the formation of these germ layers.

05:00

🔬 The Process of Gastrulation and Formation of Germ Layers

This paragraph delves deeper into the process of gastrulation, illustrating how cells from the epiblast migrate and invaginate to form the primitive streak and eventually the three germ layers. The primitive streak's growth from the caudal to the cephalic region is highlighted, as is the formation of the node, where cells invaginate to replace the hypoblast, now termed endoderm. Additionally, some cells concentrate in the middle to form a new layer called mesoderm, while the remaining epiblast becomes the ectoderm. The paragraph concludes with a visual aid, a video showing the gastrulation process, emphasizing the active participation of the epiblast in this crucial stage of embryonic development.

Mindmap

Keywords

💡Gastrulation

Gastrulation is a critical process in embryonic development that establishes the three primary germ layers: ectoderm, mesoderm, and endoderm. It is central to the video's theme as it is the main event being discussed during the third week of development. In the script, gastrulation is described as the process where cells from the epiblast proliferate and migrate towards the median plane to form the primitive streak, which is essential for the formation of these germ layers.

💡Ectoderm

The ectoderm is one of the three germ layers formed during gastrulation. It gives rise to the nervous system and the skin among other structures. In the context of the video, the ectoderm is mentioned as the top layer that remains after the gastrulation process, where cells from the epiblast transform into the ectoderm, playing a vital role in the development of the embryo.

💡Mesoderm

The mesoderm is another germ layer that develops during gastrulation and will eventually give rise to muscles, bones, and the circulatory system. The script describes how some cells from the epiblast migrate and concentrate in the center to form a new layer known as the mesoderm, which is crucial for the structural development of the embryo.

💡Endoderm

The endoderm is the innermost germ layer, responsible for the development of the digestive and respiratory systems. In the script, the endoderm is formed when some cells from the epiblast migrate and replace the hypoblast, which was initially present. This transformation from hypoblast to endoderm is a key part of the gastrulation process.

💡Epiblast

The epiblast is an early embryonic layer that gives rise to the ectoderm, mesoderm, and endoderm. The script explains that the epiblast is the starting point for gastrulation, where cells begin to proliferate and migrate to form the primitive streak, which is the beginning of the formation of the three germ layers.

💡Hypoblast

The hypoblast is an early embryonic layer that is replaced by the endoderm during gastrulation. In the script, it is mentioned that cells from the epiblast migrate and replace the hypoblast, which is located beneath the epiblast, and this replacement marks the formation of the endoderm.

💡Primitive Streak

The primitive streak is a thickening of cells that forms along the dorsal surface of the epiblast during gastrulation. It is a critical structure as it guides the migration of cells that will form the mesoderm and endoderm. The script describes the formation and growth of the primitive streak from the caudal to the cephalic region, culminating at the primitive node.

💡Primitive Node

The primitive node is the termination point of the primitive streak and is a crucial area for the formation of the notochord and neural tube. In the script, the primitive node is mentioned as the point where the growth of the primitive streak stops, indicating the cephalic region of the embryo.

💡Caudal Region

The caudal region refers to the tail end of the embryo. In the context of the script, the caudal region is used to describe the starting point of the primitive streak's growth during gastrulation, emphasizing the directional movement of cells in the embryonic development process.

💡Cephalic Region

The cephalic region is the head end of the embryo. The script uses the cephalic region to illustrate the direction of the primitive streak's growth, which moves from the caudal region towards the cephalic region, indicating the anterior-posterior axis of the developing embryo.

💡Prechordal Plate

The prechordal plate is a thickening of the mesoderm that will give rise to the head and face structures. In the script, the prechordal plate is mentioned as a membrane that indicates the cephalic region of the embryo, playing a role in the regionalization of the developing embryo.

💡Cloacal Membrane

The cloacal membrane is a structure that marks the posterior end of the embryo and is involved in the development of the urogenital system. The script describes the cloacal membrane as an indicator of the caudal region, which helps in understanding the spatial orientation of the gastrulating embryo.

Highlights

Introduction to the third week of embryonic development.

Gastrulation is the process that establishes the three germ layers in the embryo: ectoderm, mesoderm, and endoderm.

Review of the bilaminar embryonic disc formation in the second week, consisting of epiblast and hypoblast layers.

Transformation of the bilaminar disc into a trilaminar disc during the third week.

The germ layers are called 'germ layers' because they give rise to all tissues and organs of the embryo.

Description of the primitive streak's emergence on the surface of the epiblast as the beginning of gastrulation.

Cells of the epiblast proliferate and migrate towards the median plane to form the primitive streak.

Growth of the primitive streak from the caudal region towards the cephalic region, marked by the cloacal membrane and prechordal plate.

Formation of the primitive node where the primitive streak stops growing.

Invagination of cells at the center where they descend towards the hypoblast, forming the primitive pit.

Cells that invade and replace the hypoblast are now referred to as the endoderm.

Concentration of cells in the center forming a new layer known as the mesoderm.

The remaining epiblast becomes the ectoderm, completing the trilaminar embryonic disc.

The epiblast actively participates in the gastrulation process, with cells derived from it forming the new layers.

The hypoblast is completely replaced, and the new layer formed is called the endoderm.

The process of gastrulation is simple yet crucial for the formation of the three germ layers.

A video demonstration is provided to visually explain the gastrulation process.

The video shows the cutting of the embryo to observe the invagination of cells.

Final formation of the ectoderm, mesoderm, and endoderm layers, completing the gastrulation process.

Transcripts

play00:03

oi oi pessoal sejam todos bem-vindos

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mais uma vez ao Canal Bio aulas e nesta

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vídeo-aula nós vamos falar sobre a

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terceira semana do desenvolvimento na

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verdade nós vamos começar a falar sobre

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a terceira semana porque o que é que

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acontece a terceira semana é marcada por

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vários eventos importantes a que eu

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listei para vocês os principais eventos

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da terceira semana e aí vai ser um vídeo

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aula para cada evento desse então a

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gente vai começar a falar nessa vídeo

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aula sobre o primeiro evento aqui que é

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a gastrulação Então essa aqui é a parte

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1 da terceira semana então vamos lá bom

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gente então o que que a gastrulação a

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gastrulação é o processo que vai

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estabelecer no embrião as três camadas

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germinativas que são aquelas que a gente

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conhece por ectoderma mesoderma e

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endoderma mas como assim vamos relembrar

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né lá na segunda semana foi o seu

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aconteceu a formação do disco

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embrionário bilaminar ou seja eram duas

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lâminas duas camadas de células que a

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gente chamava de

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epiblasto e hipoblasto mas na terceira

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semana esse disco bilaminar ele vai se

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transformar em

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trilaminar agora vão ser 3 lâminas três

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camadas de células que a gente vai

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chamar de ectoderma mesoderma E

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endoderma então a gastrulação é

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justamente isso é o processo que vai dar

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origem a essas três camadas germinativas

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a gente diz que são as camadas

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germinativas porque é as células que

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estão presentes nessas camadas elas vão

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dar origem a todos os tecidos e órgãos

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do embrião certo então isso é a

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gastrulação mas não é só isso a gente

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tem que saber como é que esse pro e

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parece que eu vou mostrar para vocês é

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bem simples Então vamos lá bom gente

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então lá no finalzinho do vídeo da

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segunda semana eu mostrei para vocês que

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surgiram duas membranas aqui não ep

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blasto uma membrana a gente chama de

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placa precordal que vai indicar a região

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cefálica do embrião e outra membrana a

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gente chama de membrana cloacal que

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indica a região caudal do embrião certo

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a que eu tenho disco bilaminar

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em azul web blasto e Amarelo o

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hipoblasto Então como é que inicia a

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gastrulação ela inicia com o surgimento

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da linha primitiva na superfície do

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epiblasto Como assim gente as células do

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epiblasto começam a proliferar Ea migrar

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em direção ao centro ao plano mediano

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formando a é o que a gente chama de

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linha primitivo essa linha essas células

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vão proliferando das laterais migrando

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para o plano mediano para o centro do

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epiblasto na tudo isso na superfície do

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epiblasto certo elas vão proliferando e

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migrando em direção ao centro E aí essa

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linha ela vai crescendo ela cresce da

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região caudal em direção à região

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cefálica como é que eu sei que ela tá

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crescendo Nesse sentido porque olha aqui

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ó membrana cloacal que indica a região

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caudal e placa pré-cordal que indica a

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região cefálica Então as células do

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epiblasto começam a proliferar Ea migrar

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em direção ao centro formando aqui a

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linha primitiva e aí essa linha ela vai

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crescendo da região caudal em di a

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região cefálica chega uma hora que ela

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para ela cresce cresce cresce mas chega

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uma hora que ela para bem aqui ó onde

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ela para se forma o nó primitivo tá

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então gente o que é que acontece essas

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células elas vão proliferando para o

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centro se vocês ver tem aqui essa linha

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Zinho no meio ó essa linha Zinha é uma

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invaginação ou seja essas células quando

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elas chegam aqui no centro elas vão

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descer elas vão invaginar elas descem em

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direção ao hipoblasto que tá logo aqui

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embaixo então de novo olha aqui essa

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outra imagem agora ó eu vou mostrar vou

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virar o embrião para você sol

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e as células do epiblasto começam a

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proliferar Ea migram em direção ao

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centro formando a linha primitiva essa

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linha ela vai crescendo crescendo

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crescendo né em direção à região

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cefálica Quando essas células migram que

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chegam no centro elas vão começar a

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invaginar elas vão começar a descer em

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direção ao hipograxa Elas começam a

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invadir nar se vocês observarem coração

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ser que tem até um espaço aqui ó esse

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espaço é o que a gente chama de suco

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primitivo que é um espaço para onde as

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células não aí invaginando elas vão

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descendo aqui ó por esse espaço da linha

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e para onde é que elas estão descendo

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Para quê Para onde é que elas vão

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Tá bom é só outra imagem ela já tá

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mostrando aqui ó as células de sendo

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elas estão descendo do epiblasto em

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direção ao hipoblasto Mas beleza para

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onde é que essas células elas estão indo

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gente é o seguinte essa estamos que

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estão invaginando que estão saindo do

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epiblasto algumas delas Venha vem aqui

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no hipoblasto e vão substituir essas

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células quando o hipoblasto ele é todo

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substituído essa camada que a gente não

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vai mais chamar de ir para o vasto a

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gente vai chamar agora de endoderma

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então algumas células invadir não vão lá

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no hipoblasto substituem todas as

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células do hipoblasto e agora a gente

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chama de endoderma

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em outras se concentram aqui no centro

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né no meio formando uma nova camada que

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a gente chama de mesoderma e o que

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restou aqui do epiblasto vai ser o

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ectoderma e agora a gente tem aqui as

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três camadas germinativas o disco

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embrionário trilaminar

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ectoderma mesoderma e endoderma

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percebam gente que o web blasto ele

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participa ativamente desse processo né

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porque a linha primitiva ela surge não é

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bíblico as células Ale são derivados do

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epiblasto tão de novo elas invaginam

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aqui por esse espaço da linha primitiva

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algumas delas

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substituem o hipoblasto e agora a gente

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chama de endoderma

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as outras ficam aqui no meio formando

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uma nova camada que a gente chama de

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mesoderma e o que restou do epiblasto

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vai ser o ectoderma só as três camadas

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germinativas e esse é o processo de

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gastrulação Ele é bem simples aí na

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descrição do vídeo vai ter esse a

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descrição desse processo eu coloquei

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para vocês a descrição do processo na

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descrição do vídeo e para fechar esse

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assunto com chave de ouro eu trouxe aqui

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para vocês um vídeo mostrando como esse

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processo acontece então vejo ó aqui em

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azul eu tenho ep do Astro EA quem

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Amarelo o hipoblasto

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[Música]

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a região cefálica região caudal e a

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linha primitiva ó crescendo aqui parou

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aqui no nó primitivo à placa pré-cordal

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membrana cloacal E aí gente ele vai

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fazer aqui um corte no embrião para que

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a gente consiga ver as células

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invaginando então vejo aí ó ele vai dar

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um zoom

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epiblasto em azul hipoblasto em amarelo

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Vejam as células invaginando algumas vão

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lá no hipoblasto substituem as células e

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a gente chama agora dia endoderma

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Oi e a elas continuam invaginando né ó

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vai mostrar

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vão se concentrar aqui no centro

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formando uma nova camada que a gente

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chama de mesoderma

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bom e o que restou vai ser o ectoderma

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eu espero que vocês tenham gostado e a

play09:11

gente se vê na próximo vídeo aula até lá

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Related Tags
Embryonic DevelopmentGastrulationGerm LayersEctodermMesodermEndodermEpiblastHypoblastPrimitiva LineEmbryo FormationBiological Education