#16 - La journée longévité - L'étude sur l'âge biologique et les gérosuppresseurs - 10 juill 2024.

Summary

The video discusses the ongoing biological aging and gerosuppressor study, emphasizing the importance of fasting and its potential health benefits. It introduces the concept of 'longevity days,' a fasting strategy incorporating chronobiology for optimized health and longevity. The speaker also shares insights on metabolic flexibility, physical activity during fasting, and the use of gerosuppressors and probiotics to enhance the benefits of fasting.

Takeaways

• 📅 The biological aging and gerosuppressor study began in March 2024 and is expected to last for over 2 years, with the first phase still ongoing and compiling results.
• 📈 The study involves analyzing a multitude of results and is described as very exciting, with the first results being compiled during the summer.
• 🗓 The speaker continues to provide information on health aspects related to longevity, aging, and cellular aging processes, with a focus on different facets each week.
• 🌟 Today's topic is 'Longevity Day,' which is an advanced fasting approach considering chronobiology aspects to maximize health and longevity benefits.
• 🚫 The Longevity Day is not suitable for everyone and is recommended for those who are advanced in optimizing lifestyle habits for longevity, starting with individuals in good health and physical condition.
• 🏋️‍♂️ The Longevity Day involves a day of fasting with physical training during the fasting period, which is said to enhance ketone production and cellular repair mechanisms.
• 💊 The use of gerosuppressors is mentioned as a way to stimulate the same mechanisms as fasting, suggesting their potential role in health optimization.
• 🍽️ Eating 4 hours before sleep is suggested as a basic health benefit, and extending the fasting period without eating is said to have even greater health benefits.
• 🧘‍♀️ The importance of training during the fasting period is highlighted for pushing metabolic flexibility and cellular energy optimization.
• 🛌 The Longevity Day includes taking probiotics, possibly gerosuppressors before sleep, and having a protein-rich meal after training to support muscle growth and repair.
• 📚 The script mentions an ongoing study with over 800 people interested and over 680 having started the process with the partner 'Vitoli,' indicating a significant community engagement in the research.

Q & A

What is the main topic of the Wednesday live session?

The main topic is the study on biological aging and gerosuppressors, with a focus on the concept of 'longevity days' and how fasting can be optimized for health and longevity.

How long is the research process on biological aging and gerosuppressors expected to take?

The research process is expected to take over 2 years, with the first phase still ongoing and the second phase dependent on the outcomes of the first.

What are 'longevity days' and how do they relate to fasting?

'Longevity days' refer to an optimized fasting approach that considers various aspects of health and chronobiology to maximize the benefits of fasting on longevity and health.

What is the significance of the hormone growth hormone (GH) in the context of fasting?

During fasting, there is a progressive increase in the growth hormone (GH), which helps to preserve muscle mass and stimulate repair mechanisms in the body.

How does physical activity during fasting affect the body's metabolic processes?

Physical activity during fasting can increase the production of ketones, stimulate autophagy, and enhance the performance and health of mitochondria, leading to more efficient energy production.

What is the recommended approach to consuming meals after a period of fasting?

It is recommended to consume a meal rich in animal protein after fasting, with at least 50 grams of protein to stimulate muscle growth and support the mTOR pathway.

What is the role of the mTOR pathway in the context of the 'longevity days'?

The mTOR pathway is involved in cell growth and development but also accelerates aging processes. It should be stimulated specifically after exercise to benefit muscle growth and then allowed to decrease to support cellular repair mechanisms during the night.

Why is it suggested to avoid eating for a period of 4 hours before going to sleep?

Avoiding food intake for 4 hours before sleep can already provide health benefits by initiating the body's production of ketones and starting the process of time-restricted feeding.

How does the speaker propose to modulate the microbiome during fasting?

The speaker suggests taking probiotics during the fasting period to help modulate the intestinal microbiome, which is known to change composition during fasting.

What is the significance of the study on biological aging and how can one participate?

The study on biological aging aims to analyze and understand the aging process better. To participate, one should create an account on biotwin, identify as part of the Vitalie study in the profile questionnaire, and follow the procedure for data collection and submission.

What is the speaker's next topic for the Wednesday live session?

The speaker's next topic will be about the 'pulsed approach,' a new concept that will be part of their 5th book, expected to be released in January 2025.