Stem Cells Explained - Easily Most Important Medical Discovery Of Our Times - Brain Surgeon Dr. Alok

Summary

The transcript explores the transformative potential of stem cell therapy, particularly in treating conditions like autism and neurological disorders. It discusses the healing properties of stem cells, their ability to regenerate damaged tissues, and the significant progress made in India, despite Western skepticism. The speaker highlights the challenges faced due to established medical and pharmaceutical interests, emphasizing the importance of patient outcomes as the driving force for innovation in this field.

Takeaways

• 🌟 Stem cells have the potential to heal damaged joints and can be used in treatments for conditions like tennis elbow and shoulder inflammation.
• 🧬 Stem cells are found in the body's bone marrow and umbilical cords, and they have the unique ability to become any other type of cell in the human body.
• 🚀 The application of stem cells in medicine has advanced significantly in the last 5-10 years, moving from a concept to practical treatments.
• 💊 Stem cells offer a third option in medicine, aside from drugs and surgery, by promoting biological healing through cell-to-cell interactions.
• 🧠 In the realm of neurological conditions, stem cells are particularly promising due to the brain's previously believed inability to regenerate.
• 👶 There is a growing focus on using stem cells to treat children with neurodevelopmental disorders such as autism, cerebral palsy, and intellectual disabilities.
• 📈 The incidence of autism has increased dramatically, with statistics showing a rise from 1 in 160 children to 1 in 36 children in the last decade.
• 🔬 Pioneering research has identified specific areas of the brain that are not functioning properly in children with autism, using advanced imaging techniques like PET CT scans.
• 💉 Autologous stem cell therapy, where stem cells are extracted from the patient's own body, is preferred over allogenic stem cells due to better compatibility and lack of preservatives.
• 🌐 The advancement of stem cell therapy has been hindered in the West due to political and ethical debates, allowing countries like India, China, and Japan to become leaders in the field.
• 🏥 Despite opposition from various lobbies and the potential threat to established medical and pharmaceutical industries, the success of stem cell therapy is supported by patient outcomes and scientific research.

Q & A

What is the primary application of stem cell therapy discussed in the script?

The primary application discussed in the script is the use of stem cell therapy for treating inflamed joints, as well as neurological conditions and neurodevelopmental disorders such as autism, cerebral palsy, and intellectual disabilities.

How are stem cells typically sourced for treatment according to the script?

Stem cells can be sourced from a patient's own bone marrow or fat (autologous), or from other sources like umbilical cords (allogenic).

What is the fundamental property of stem cells that makes them useful in medical treatments?

Stem cells have the ability to multiply and differentiate into any other type of cell in the human body, which is fundamental to their use in medical treatments.

What is the difference between autologous and allogenic stem cells as mentioned in the script?

Autologous stem cells are taken from the patient's own body, while allogenic stem cells are taken from another person, such as those found in umbilical cords.

Why does the speaker prefer using autologous stem cells over allogenic ones?

The speaker prefers autologous stem cells because they are fresh, without preservatives, and the patient's body is more likely to accept them without complications.

What is the significance of the speaker's work in the field of stem cell therapy for autism?

The speaker's work is significant because they published the world's first scientific paper on the role of cell therapy in autism and have treated thousands of patients, leading the way in this field.

How does the speaker describe the increase in autism prevalence over the years according to CDC figures?

The speaker describes a phenomenal increase in autism prevalence, from one in 160 children 10 years ago to one in 36 children in the present day, based on CDC figures.

What challenges has the speaker faced in promoting stem cell therapy for autism?

The speaker has faced opposition from various lobbies, including those with economic interests in the status quo, and has been criticized by 400 signatories in the field who are opposed to this work.

What is the role of cerebrospinal fluid in administering stem cell therapy to the brain as per the script?

Cerebrospinal fluid circulates around the brain and spinal cord. By injecting stem cells into the spinal fluid, they are carried directly to the brain, where damaged areas attract the stem cells for repair.

How does the speaker address the issue of Big Pharma's potential threat due to stem cell therapy?

The speaker acknowledges that Big Pharma may view stem cell therapy as an existential threat because it could replace the need for certain medications, and shares an anecdote of a doctor being pressured to stop his work on stem cells and diabetes.

What is the speaker's view on the future of stem cell therapy in the mainstream medical field?

The speaker anticipates that stem cell therapy will eventually take off in the mainstream medical field, despite current resistance, because of its potential to heal in ways that drugs and surgery cannot.

Outlines

00:00

🌐 Exploring Stem Cells: Basics and Applications

The video introduces the concept of stem cells, detailing their basic properties and applications in modern medicine. Stem cells can be harvested from bone marrow and umbilical cords, and have the potential to transform into various cell types to repair bodily damage. The discussion touches on their potential in treating joint inflammations and their fascinating future prospects.

05:02

📈 The Rising Prevalence of Autism

The discussion highlights the significant increase in autism prevalence over the past decade, with current statistics showing 1 in 36 children affected. Various potential causes, including lifestyle factors, mobile phone radiation, and modern diets, are explored. The conversation emphasizes the need for deeper understanding and research into the biological factors contributing to autism.

10:03

🧠 Understanding Autistic Brain Function

The video delves into pioneering research on the brains of autistic children, identifying specific areas that function differently. Advanced brain imaging techniques have revealed underactive and overactive regions, providing insights into the unique capabilities of autistic individuals. Notable figures like Elon Musk and Albert Einstein are mentioned as examples of autistic individuals with extraordinary abilities.

15:05

🩺 How Stem Cells Aid in Healing

The speaker explains the mechanisms through which stem cells aid in healing by differentiating into necessary cell types and releasing growth factors. They discuss the process of extracting stem cells from bone marrow and fat, and contrast autologous (self-derived) with allogenic (donor-derived) stem cells. The benefits of autologous stem cells in treating conditions like autism are highlighted.

20:06

🌍 India's Leadership in Stem Cell Therapy for Autism

The video celebrates India's pioneering role in publishing the first scientific paper on stem cell therapy for autism. The discussion covers the international recognition and the influx of patients from around the world seeking treatment in India. The speaker reflects on the challenges and resistance faced from established medical and pharmaceutical industries.

25:08

💡 Challenges and Resistance in Stem Cell Therapy

The narrative shifts to the challenges faced by stem cell therapy, including resistance from the pharmaceutical industry and entrenched medical practices. Personal anecdotes illustrate the intense opposition from various quarters, highlighting the socio-economic factors at play. Despite these challenges, the success and support from patients underline the transformative potential of stem cell therapy.

🔬 Hypotheses and Future Prospects

The speaker discusses various hypotheses regarding the causes of the decline in brain function in autistic children, touching on medication, lifestyle, diet, and birth-related factors. The potential of stem cell therapy in reversing these declines and enhancing the special abilities of autistic children is emphasized, suggesting a revolutionary approach to understanding and treating autism.

Keywords

💡Stem Cells

Stem cells are undifferentiated biological cells capable of giving rise to specialized cells and potentially dividing indefinitely under certain conditions. In the video's context, they are highlighted as a revolutionary treatment for various conditions, including joint inflammation and neurological disorders. The script discusses how stem cells can be extracted from one's own bone marrow and have the unique ability to become any other cell in the human body, which is crucial for regenerative medicine.

💡Neurological Conditions

Neurological conditions refer to disorders of the brain and nervous system. The script emphasizes that these conditions were previously untreatable with drugs or surgery due to the brain's inability to regenerate. However, stem cells offer a new avenue for treatment by biologically repairing damage, which is a significant theme in the video.

💡Autologous Stem Cells

Autologous stem cells are those taken from an individual's own body, such as from bone marrow or fat. The script explains that these cells are preferred for treatment because they are less likely to be rejected by the body and do not contain preservatives. This concept is central to the video's discussion on the benefits of using one's own stem cells for therapy.

💡Umbilical Cord Stem Cells

Umbilical cord stem cells are harvested from the umbilical cord after birth and are known for their richness in stem cells. The video mentions that these cells are often collected and stored for potential future use but are considered less preferable than autologous cells due to the preservatives used in their storage process.

💡Neurodevelopmental Disorders

Neurodevelopmental disorders, such as autism and cerebral palsy, are conditions that affect the development of the brain and nervous system. The script discusses the potential of stem cell therapy to treat these disorders, particularly in children, and how it could improve their quality of life and independence.

💡Cerebrospinal Fluid

Cerebrospinal fluid is a clear fluid that circulates around the brain and spinal cord, providing cushioning and nourishment. In the context of the video, stem cells are injected into the cerebrospinal fluid to treat brain-related conditions, as the fluid carries the cells directly to the brain.

💡Biological Healing

Biological healing refers to the body's natural processes of repair and regeneration. The video contrasts this with traditional treatments like drugs and surgery, highlighting stem cells' role in facilitating this innate healing process.

💡Growth Factors

Growth factors are naturally occurring substances that stimulate cell growth, division, and repair. The script explains that stem cells release growth factors, which aid in the healing process by promoting tissue regeneration and attracting new blood vessels to the area of injury.

💡Inflammation

Inflammation is the body's natural response to injury or infection. The video discusses how stem cells can reduce inflammation in the body, which is important for the healing process, especially in conditions like joint inflammation.

💡Neurotypical

Neurotypical refers to individuals whose neurological development and functioning are considered to be within the typical range. The script uses this term to differentiate between those who do not have neurodevelopmental disorders and those who are neurodiverse, emphasizing the uniqueness of each individual's brain.

💡Colonial Hangover

Colonial hangover is a term used in the script to describe a perceived bias where Western ideas and practices are automatically given more credibility than those from other regions, such as Asia or India. This concept is discussed in the context of the resistance faced by Indian stem cell therapy pioneers.

Highlights

Stem cells can be used for healing inflamed joints and have been applied in the treatment of tennis elbows and shoulders.

Stem cells are found in umbilical cords and bone marrow and have the potential to become any cell in the human body.

Stem cell therapy is a biological healing process that can repair damage in the body without the need for drugs or surgery.

Neurological conditions, previously untreatable, can now be addressed with stem cell therapy due to their regenerative properties.

Stem cells have been used to treat severe conditions like motor neuron disease, which affected Stephen Hawking.

The rise in autism cases has been linked to various factors, including lifestyle and environmental influences.

Stem cell therapy has shown promise in treating neurodevelopmental disorders in children, such as autism and cerebral palsy.

Advancements in brain imaging technology, like PET CT scans, have helped identify areas of the brain affected by autism.

Stem cells have the unique ability to multiply and differentiate into various cell types, aiding in the body's natural healing process.

Autologous stem cells, taken from the patient's own body, are preferred over allogenic stem cells due to their freshness and compatibility.

Stem cell therapy for autism involves injecting cells into the cerebrospinal fluid, allowing them to reach and repair damaged brain areas.

India has become a leader in stem cell therapy research and treatment, attracting patients from around the world.

The first scientific paper on the role of cell therapy in autism was published by an Indian researcher, setting a precedent in the field.

Stem cell therapy's success in treating autism challenges the established medical and pharmaceutical industries.

Resistance to stem cell therapy in the West is partly due to historical bans on embryonic stem cell research and funding.

The potential of stem cell therapy to replace traditional treatments poses a threat to big pharmaceutical companies and their business models.

Stem cell therapy's impact on autism has shifted the narrative from a hopeless condition to one where patients can develop unique abilities.

The hypothesis that the decline in autistic children's brain function could be due to medication or other factors is explored.

The importance of patient support and advocacy in the face of opposition to innovative treatments like stem cell therapy is highlighted.

Transcripts

you either use the internet for fun or

you use the internet to grow you're here

to grow welcome to TRS clips

let's take a deep dive into stem cells

yeah

from literally the 101 till whatever it

is in 2023 up till what it's going to

become in 10 years time uh I think only

one or two people on this show out of

500 episodes have ever even brought it

up uh Chris gethin who's a world around

trainer brought it up because he said

that all his information on his tennis

elbows shoulders went down because you

take stem cells and you inject it into

those joints and then there's a

treatment that follows over the course

of one or two days and eventually that

joint heals a lot of my friends even

myself I have been weight training for a

while you do end up getting inflamed

joints so I know that that's one of the

most basic applications and the only

other thing in the word stem cells is

that again please correct me if I'm

wrong they found in babies umbilical

cords and I believe they're found in

your bone marrow that's right am I right

absolutely you extract them from your

own bone marrow stem cells are the cells

that can become any other cell in your

human body very accurate yeah uh it can

also become a nerve cell absolutely but

you you guys only figured out how to

turn it into a nursery in the last five

to ten years longer than that yeah okay

but I mean like application wise

probably in the last five to ten years

which is why I said the market shoe

marketing

uh anyway so you extracted out of your

bone marrow yeah and then I don't know

what happens I don't know what happens

in your lap the story of stem cells is

fascinating okay it's

it's not just

what's happening now it's what the

future is going to be all right

when I was a medical student

what I'm already doing now would come

under science fiction then if in the

1980s we spoke about this it would be

pure science fiction but it's happening

so what exactly are stem cells now in

the world of medicine we have two broad

treatment interventions we have drugs

medicines pills injections okay and we

have surgery you go you cut remove

something suture so there's medicine

there's surgery now

there there are many conditions where

there are no drugs that can help and

there's no surgery that can help

of all of these the most important are

in nervous system diseases because

neurological conditions the the brain

and the nervous system does was believed

to not regenerate so once there was

damage there was no drug you could give

and there was no surgery you could do

now in the but

stem cells are cells which not being a

drug not being surgery

what they do is they repair

damage in the body biologically you know

so it's like imagine if you ever if you

have a cut in your hand how your wound

heals that's a biological healing all

right so stem cells help in biological

healing right not as a drug not as a

surgery but cell to cell interaction

this is the way the body had meant to

heal it's a natural system of healing

now

we have stem cells in different parts of

our body but they take care of the

normal wear and tear so you have a

certain injury Here There and the local

stem cells will help heal it locals

themselves you have stem cells in the

brain your stem cells are on your hair

your stem cells little they're very

small amounts they're just for the local

wear and tear okay

but if there is a severe damage like if

you have

a brain injury you have a spinal cord

injury in adults there are some uh in

adults there are some conditions that

are potentially fatal one such condition

is something called motor neuron disease

something that Stephen Hawking had you

know the famous scientist from from

Cambridge

there's no there was a solution to this

you know these people just died but

because there was no drug and no surgery

but now with the availability of stem

cells we can actually help them but the

really more exciting area the area which

is now in the last few years become my

focus is actually children

because in children there are certain

neurodevelopmental disorders such as

autism a cerebral palsy uh intellectual

disability where the brain from birth

itself okay is not functioning

appropriately and because of that there

are a whole lot of symptoms that because

of which these children cannot lead

independent lives now the thing about

autism and this is something the world

is just not recognizing

you know there is something in the USA

called CDC Center of Disease Control

they are the ones who give all the

statistics on Covert and everything else

they've got the most accurate figures in

the world on disease

and if you just see the figures of covet

10 years ago one in 160 children had

autism okay CDC figures on autism

three years ago it was one in 54

children

two years ago it was last year it was

one in 44. this year it is 1 in 36. okay

so from one from one child out of 160

children having autism 10 years ago to

one in 36.

today is a phenomenal increase at this

rate in the next 20 years every third

child will have autism why is this

happening now that is a million dollar

question because it's got to do a lot

with multiple things they are you know

there are multiple factors there some

very controversial some uh you know not

clear so it's got to do with lifestyle

it's got to do with a whole lot of

things there are some people who said

vaccines are responsible for it but

that's again very controversial it's not

something in the medical we talk much

about there's talk about mobile phone

radiation causing it you know there is

talk about modern diet causing it there

is there is this conversations about you

know people having children later in

life because you know the older you get

if you have children you know the your

child is more likely to have autism so

the causes of autism are many so

biologically speaking what happens in an

autistic brain yeah exactly so this is

something we've done pioneering work on

we were among the first in the world

surprisingly despite the fact that there

is such a high incidence of autism

nobody had really looked deep into the

brains of these children to identify

which parts of the brain are not working

and we actually did this with sir there

is now newer brain Imaging see earlier

we had just CT scan and MRI scans but

now we have something called PET CT scan

positron emission tomography City in

which which shows you which parts of the

brain are working normally which are

working less and which are working more

all right and it's a color scan so it's

easy to you know the green color is

normal blue is working less yellow is

working more

so we have identified that you know you

know these areas the Deep area of the

brain we are talking about the limbic

system the medial temporal lobe and the

small brain the cerebellum we have found

because we have done scans in over 3000

children

with autism and we actually have clearly

identified almost for the first time in

the world which parts of the brain are

not working appropriately in children

with autism and we've published this in

a scientific paper in a world Journal of

nuclear medicine was it the lower brain

the animal brain that was not very

reactive absolutely so that means the

higher brains almost exactly exactly why

this whole angle about autistic kids

being Geniuses exactly wow you know Elon

Musk had awesome do you know that you

Google them Elon Musk had autism as a

kid but this man is the richest man in

the world today and he changed the way

the world thinks because these people

have and I I'm you know I'm so happy you

picked this up because most people don't

pick it up you looked at what positive

they have the whole world is looking at

what they don't have and you know Albert

Einstein and autism you know that okay

and many of many of our big Tech

Geniuses who run some of the biggest

companies in the world they had they

didn't have friends you know a minor

version of autism is something called

Attention Deficit Hyperactive Disorder

and then there is learning disabilities

you know some of these people could not

get through college and school they

didn't choose not to whether it's Bill

Gates or Steve Jobs or they didn't

graduate from college but they had a

Brilliance that was different these the

evolution of the human speech exactly

you know this is exactly what I've been

talking about people doing this is the

next step in human evolution because and

how do we know it because when we do the

scans we not only find parts of the

brain which are which are not working

which we sort of anticipated but there

are parts of the brain which are working

more

and we actually found and this is shown

in our published paper that the brains

of children with autism actually start

functioning higher in the earlier years

you know they're functioning more than

what is called neurotypical children and

then they decline so now we don't use

the word normal anymore we say

neurotypical people like you and me are

neurotypical

children with autism and neurodeiverse

there's a there's a change in the

mindset that you know just like somebody

can be tall somebody can be short

somebody can be fresh somebody can be

dark somebody can have a brain that is

like what we have and somebody can have

a brain like a person with autism so we

use the word neurotypical neurodiverse

but normal kids actually start off lower

but then proceed to grow so what we

found

is that when we give these children

cell or stem cell therapy

that blue part of the brain which was

the blue it's not actually blue it's on

the scan appears blue it's called hyper

metabolic that's brain that's little

less active functioning less that this

gets activated this gets repaired and

this becomes functional and once it

becomes functional these children don't

just start leading what is called normal

lives they all have something peculiar

different unique to give to the world

in which they completely Excel things

which are unimaginable things that you

and I cannot even imagine

now start functioning so first you know

go back to your question how do stem

cells work so you answer it yourself the

first thing about stem cells is that

when the stem cells of the ability to

multiply okay and when they divide

they make a copy of themselves another

stem cell but they also become any other

cell of the body depending on where you

put it so if I take a stem cell and I

put it in the in the nervous system

it'll become a nervous cell if I put it

in the muscles it'll become a muscle

cell so depending on where you put it

it becomes that so this amazing property

of converting into other cell types okay

and the ability to multiply along with

that what they do is they release

certain positive chemicals in the body

called growth factors these help in the

healing process they also attract fresh

blood tourism called angiogenesis this

combination of being able to multiply to

divide to release growth factors to get

fresh blood they reduce the inflammation

the body they modulate the immune system

there are several mechanisms basically

this helps repair what is

non-functioning and once you and there

isn't there's no drug that can do it

there's no surgery they can do it now

you mentioned about bone marrow and

umbilical cord so I just want to clarify

that broadly speaking cell or stem cells

are of two types what is autologous that

means when you take from the body so

from the body you can take either from

the bone or you can take from the fat

these are two areas from which you can

actually get stem cells

then there are stem cells which you take

from now so autologous is you take from

your own bone and put it back in the

body

allogenic is when you take from somebody

else okay so for example the umbilical

cord that connects the mother and baby

at birth this is very rich with stem

cells so there are companies that go and

collect this normally this is thrown in

the garbage

in some children nowadays in fact most

the children they actually save it you

know so if you save it you can use it in

the future for the same child but the

other companies that collect it from

everywhere and they package it and it's

available as a as a package sort of

umbilical cord thing so this is somebody

else's cells and then your own cells you

know we don't use the package umbilical

cord because I believe your own cells

are much better than somebody else's

cells on your body for your body because

one their own cells or body will accept

it too it's fresh there's no

preservative you know you just take what

we do is we take from the bone marrow we

filter it we run it through machines

called centrifuges isolate the stem

cells and when the few hours put it back

whereas those are preserved they belong

to somebody else they are cry or Frozen

and they add a preservative so if I ask

you which is better take an orange and

make fresh orange juice or have a canned

orange juice you know fresh orange juice

is better so that's the difference

between umbilical cord and what we do

that is autologous now the thing about

autism is that once you repair you know

and so and the other thing very

important

what we do autologous we can inject it

in the spinal fluid so you know our

brain uh it continues doubt as the

spinal cord and surrounding the brain

there is a fluid called cerebrospinal

fluid it's a fluid that circulates can

you know it's continuously circulating

so what we do is with a little needle

prick we inject it into the lower back

into the fluid because this fluid

carries it to the brain and when it goes

to the brain the part of the brain

that's not functioning properly or

that's damaged it pulls the stem cells

towards it automatically automatically

the normal brain doesn't it's like you

know let's say you are hungry and I've

just had food and you know somebody

comes in with food what's going to

happen you're going to make a grab for

it I'm full I won't take it so the body

is like that you know the body tissues

are they're not greedy the the parts

that don't want it will not pull the

stem cells but the damage parts will

and there's a lot of research to show

that the stem cells home in uh to the

damaged area actually uh has the stem

cells come to them

so we inject it in the spinal fluid so

it goes directly to the brain now the

umbilical cord cells because they have a

preservative you cannot inject it in the

spinal fluid you have to give it

intravenously like an injection now when

you do that it goes from there to the

heart then to the lungs from the lungs

back to the heart and then the heart

sends it to the brain so there's a long

journey in fact a lot of these stem

cells get trapped in the lungs so for

the first time in medical history you

know there is now a solution for autism

which is affecting one out of 36

children in America in India the figures

are about one in hundred but I think

that's because

we aren't picking up enough I mean the

documentation is not so so solid and

concrete actually I think the incidence

is much more why why do you think it's

much more no I'll be much more official

than India okay no no the official

figures for India is one in 100 official

figures for America's one in 36. I think

because they are more they document more

properly here a lot of kids in The

Villages and all that it will not get

diagnosed now what is you know what is a

matter of great pride for me like

serious pride is that the world's first

scientific PubMed index paper on the

role of cell therapy in autism is

published by us okay the world's first

paper the second paper came from China

the third from Italy the fourth and

fifth came from Duke University America

now that is something nobody can take

away they can only be one person who

climbs Mount Everest first or one person

who lands on the moon first

everybody else follows so now all the

papers on cell therapy or stem cell

therapy in autism have to cite us

because we are the first to publish and

when I say when I say the world's first

paper I never say I publish the world's

first paper although I'm saying it to

you I always say the world's first paper

on Cell Therapy in autism came from

India

this is a matter of Pride for me that

our country published the world's first

paper on something new and completely

Innovative after that we have

a total of 15 other papers on Cell

Therapy in autism and uh a second one

after that was published in a very

prestigious Journal you know all are

published in very prestigious journals

and we have a total of 106 scientific

papers which is the largest in the world

so this is an area where our country is

leading the way you know not just me is

our country there are a lot of

foreigners actually come to India for

stem cells yes I have treated patients

from 75 different countries 75. do they

basically come here because it's more

budget-friendly uh they're coming

because it's not available there our

results are better and also because yeah

of course it's a little more budget

friendly but you have to understand

people travel 20 hours we I get patients

every week you know I get patients

coming from America and Australia from

England they fly 15 20 hours to come

here okay so firstly this treatment is

not available everywhere else it's not

available as free you know the way it is

here because a lot of the western world

hasn't accepted why

okay so there's a there's a long story

behind it what happens is that um

in 2000 around 2001 President George

Bush he had banned uh embryonic stem

cells you know so okay to explain to you

we do from the bone marrow but you can

also get stem cells from the embryo you

know uh you know you have test tube

babies you have IVF you should be

familiar with IVF so in that you have

what is called spare embryos okay that

are you so you can actually make stem

cells from that as well now as you are

aware the you know on the Roman Catholic

Church doesn't permit abortion of family

planning in fact in America there's a

law the Supreme Court actually you know

create I think passed something about

abortion so abortion in many states are

not allowed that is because the

Christian thinking is Life Starts at

conception when the sperm and egg come

together Life Starts so anything you do

after that you are killing a living

person so that's the whole family

planning abortion debate

in the Western World George Bush the

player had banned Federal funding he

said the government will not pay for

research for embryonic stem cell but

people's hearing is let me know they

what people remember George Bush banned

stem cells he didn't ban stem cells he

banned Federal funding he said

government will not pay for research for

embryonic stem cells

again what most people don't remember is

when Obama became president one of his

earliest executive decisions was to lift

that ban okay now we are not using that

okay that is like you know the whole

mistake the whole mess is right now it's

like beverages beverages has got alcohol

it's got canned juice you know Pepsi

Coke Etc and he's got homemade orange

juice they're all Beverages and what

you're doing is you're taking something

for alcohol and implying it for homemade

orange juice there's no connection

that's the mistake there so what

happened because of that in the western

world in America England Canada

this all over Europe This therapy did

not develop it developed in India China

Korea and Japan we four countries are

the leaders India China Korea and Japan

we are way ahead of the West now the

West you know they just can't accept it

I mean because we are pioneering we have

done I've done close to 13 000 patients

already in the last 15 years you know

they are just starting you know at their

at some of their facilities they're just

starting to do the work in Medical

Careers experience plays a huge absolute

role yeah so that is happening and the

problem is not just that they are doing

it our own doctors we have what I call

and I say it openly normally we have

what is called a colonial hangover so

when somebody with a white skin an

attack from Harvard Stanford Oxford

comes and says Well everybody's blah

blah blah blah they are praising him

doing the Arty you know but when the

same thing comes from Asia or India they

don't have the same respect for it so I

call it Colonial hangover you know it

really is like that we are pioneers the

world is following what we are doing we

are being quoted when patients go to

doctors from there they are actually

being told to come here also I'm

assuming that in the long term if stem

cell therapy really takes off in the

mainstream which I anticipate that it

will it is it's almost it is it will

affect big Pharma badly or you know

you're brilliant here because this is so

you know you're you're touching the key

points one of the reasons that I was

going to mention about it that's stem

cell therapy hasn't taken off it doesn't

have backing from Big Pharma in fact a

very senior executive from a

multinational company told me says Dr

Sharma you are an existential threat to

us I said like what so he said that if

you make everybody okay who will take

her medicines um I'll give you the big

medical companies I mean little big

medicine companies they don't want stem

cells to take he used that word

existential threat I mean that's huge

I'll give you an example I have a friend

of mine in Jordan

uh and we have a meeting all our stem

cell therapy doctors in Europe once a

year we meet in different parts of the

world and three years ago we met in

America and he were actually standing on

the stage in front of hundreds of us and

actually big tall tough guy and was in

tears you know you know the story told

us this guy was using stem cells to

reverse diabetes and I've been to Jordan

I've met his patients he was completely

reverse diabetes completely okay people

on insulin off he said and he said put

publicly in front of all of us that he

was threatened by the company's

manufacturing insulin because it's a

trillion dollar not directly but wires

you know why and he was told either you

stop

your work on Diabetes will let you

continue your other work or we will shut

you down completely and he said I had to

shut down okay now he's saying this

publicly all right because that

insurance a trillion dollar industry

they cannot have that be replaced so

here is somebody from Jordan telling me

that he had to stop his work on stem

cells and diabetes because

now for I'm not being you know

threatened but yes I have been

attacked really I've been seriously

attacked you know they've made so much

efforts in fact 400 I'm saying it

publicly 400.

400 people

in this field in the field of autism

have got together and I'm not saying it

they gave an article in times of India

saying we are 400 signatories they are

opposed to this work why because there

is an entire economy that sustains on

these kids never getting okay let's say

you're running a rehabilitation center

and these kids are coming you know a

child cannot talk he comes to you for a

lifetime of speech therapy I treat him

he starts talking he stops coming to you

so your business is directly affected so

there's this very strong Lobby that is

making all-out attempts to shut me down

okay but we got our results and it made

attempts they were unsuccessful and who

stood by us our patients when people

made these attempts our patience stood

up you know they signed petition they

went on petition.org they wrote to the

Prime Minister help Minister and

commissioner and it was flooded with

support for us So eventually what

matters is people if the parents of

children who have improved are standing

up and talking for us

that's real okay because no pen is going

to support something that has not work

for his child whenever you do anything

Innovative whenever you do anything

different you challenge the status quo

there is an established business model

of people who are who are sustaining on

something not happening okay I want to

threaten that they are going to rise up

and and speak about you and the real

pity is that all these people none of

these people

this should come in if you're if you say

you're working in this field and there

are people coming from all over the

world here

they've not even once come and asked me

okay to share our results talk to us you

know speak to us in fact you know I mean

at least you should be wanting to learn

and know what is going on no there's

just an opposition so anything new that

anybody does there will be resistance

there will be opposition people will try

to shut you down but you just have to

believe you have to believe in yourself

to believe in your work and most

important you have to you know it's the

people who are who are improving that

become your support and your structure

so we have completely changed the

thinking in the in the field of autism

and neurodevelopmental disorders from

nothing can be done to the fact that we

can almost not just completely reverse

it but when you reverse it these kids

not just go back to Independence you

start seeing the special abilities in

them so the special abilities thing is

something I want to Deep dive in but

first I want to put forward a hypothesis

and correct me if I'm wrong medically

um you spoke about how traditionally

speaking when a child is autistic

initially in his or her life the growth

of the brain and the functioning of the

brain is great greater than the average

kid and then there's like a dip yes

that's the traditional way that things

work do you think that that dip could be

happening because of the medication

given to the kid

there could be medications there are

lots of theories about it it could be

lifestyle diet stresses you know there

are there are a million causes as to why

uh there are some some people talk of

genetics a small percentage 15 to 20

percent okay there's a genetic

background but a majority of it is

lifestyle sometimes during the birth

process

like you know if the birth that's why

the role of gynecologist is just so

important because if there's a little

hypoxia

you know less of oxygen to the the brain

of the child when the child is being

delivered that can cause

um the kind of uh brain damage that we

are seeing now in autism so there can

there could be many reasons nucleus

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