How do scientists know they hooked up?
Summary
TLDRThis video explores the intricate journey of modern humans, tracing their origins from Africa and highlighting interactions with other ancient species, such as Neanderthals and Denisovans. It reveals how genetics showcases a complex family tree, with modern humans carrying traces of these archaic relatives. The narrative emphasizes the evolving understanding of our ancestry and the research methods that shape these insights. Additionally, the video introduces Ground News, a platform designed to help users navigate diverse news coverage and uncover blind spots in their media consumption, fostering a more informed public dialogue.
Takeaways
- 🧬 Modern humans (Homo sapiens) share genetic material with Neanderthals, with many individuals having less than 2% Neanderthal DNA.
- 🔍 Early interpretations of Neanderthals as primitive ancestors have been challenged by recent research, revealing them as complex beings.
- 🧪 Svante Pääbo's work in extracting and sequencing ancient DNA has been pivotal in understanding human evolution.
- 🔗 Genetic studies indicate significant similarities between Neanderthal and modern human genomes, supporting the idea of interbreeding.
- 🌍 Evidence shows that Neanderthals and Homo sapiens coexisted and interacted in Europe, as suggested by archaeological finds.
- 🗺️ New discoveries, like a baby tooth in France, highlight direct evidence of Neanderthal and Homo sapiens interactions.
- 🔄 The Four-Population test reveals a genetic connection between Neanderthals and non-African modern humans, suggesting historical mixing.
- 🧑🤝🧑 The complexity of human ancestry includes other ancient humans, such as Denisovans, contributing to our genetic makeup.
- 📚 Ground News is introduced as a tool for comparing how different media outlets cover stories, emphasizing the importance of media literacy.
- 💡 The narrative of human ancestry is evolving, showcasing a messy and interconnected family tree rather than a linear progression.
Q & A
What does the script suggest about the complexity of human ancestry?
-The script suggests that human ancestry is much more complex than a simple linear progression, with multiple waves of migration, mixing with different archaic human species, and a 'messy' family tree.
Who are the Denisovans and how do they relate to Homo sapiens?
-Denisovans are another type of ancient human found in Siberia, and genetic evidence shows that they also interbred with Homo sapiens, indicating interactions among different human species.
What is the significance of Neanderthals in the context of human evolution?
-Neanderthals are portrayed as both close relatives and ancestors of modern humans, representing a separate branch of the human family tree, contributing to our genetic heritage.
What are some outcomes of human migrations mentioned in the script?
-Outcomes of human migrations include some groups dying off, others returning, some flourishing, and various populations mixing with unfamiliar groups.
How does the script address the idea of unknown archaic humans?
-The script indicates that our genomes may contain traces of additional unknown archaic humans whose remains have not yet been discovered.
What does the term 'blind spot' refer to in the context of news consumption?
-'Blind spot' refers to news stories that receive little or no reporting from specific political perspectives, highlighting areas where media coverage may be lacking.
What is Ground News and what features does it offer?
-Ground News is a platform that aggregates news stories from various sources, allowing users to compare how different outlets cover the same story, including their political bias and factual accuracy.
How does the script emphasize the importance of research methods in understanding news?
-The script emphasizes that there is a lot of nuance and uncertainty in research methods, and complexity is added when discoveries are reported in the news, affecting public perception.
What is the aim of the Howtown channel, as mentioned in the script?
-The aim of the Howtown channel is to explore not just what we know about human history but also the various methods we use to discover and understand that information.
How does the script suggest supporting the channel?
-The script suggests supporting the channel by signing up for Ground News, which not only helps the viewer navigate the news but also provides a way to support Howtown.
Outlines
🧬 Exploring Human Ancestry and Neanderthals
The narrator discusses the evolutionary relationship between modern humans and Neanderthals, suggesting that Neanderthals are both distant relatives and part of our ancestral lineage. This perspective emphasizes the complexity and messiness of the human family tree, challenging the conventional understanding of human ancestry. The narrator portrays this view as more realistic and compelling.
📰 Navigating News Coverage with Ground News
The narrator highlights the significance of understanding how scientific discoveries are reported in the media, particularly in relation to the human ancestry discussion. They introduce Ground News, an app and website developed by Harleen Kaur, which aggregates news from around 50,000 sources. Ground News allows users to compare different outlets' coverage, revealing political biases and factual reliability. An example is provided regarding a study on Neanderthals caring for a disabled child, showcasing how various news outlets interpret the story. The narrator appreciates the 'Blind Spot' feature, which identifies underreported stories from specific political perspectives, encouraging users to explore Ground News for better media understanding.
Mindmap
Keywords
💡Homo sapiens
💡Neanderthals
💡Denisovans
💡Genetic mixing
💡Archaic humans
💡Human family tree
💡Research methods
💡Ground News
💡Political bias
💡Blind Spot feature
Highlights
The fossil record has revealed multiple waves of human migration out of Africa, showcasing complex patterns of survival and intermixing.
Neanderthals are identified not just as separate species but as part of the human family tree, being our 'great uncles' and also ancestors.
Recent studies indicate that modern humans interbred with Neanderthals and Denisovans, adding layers to our genetic heritage.
Denisovans, a previously lesser-known group, also mixed with Homo sapiens, further complicating our understanding of human evolution.
Genetic analysis shows evidence of unknown archaic humans, indicating that our evolutionary history is still being uncovered.
The depiction of the human family tree is now recognized as much messier and more interconnected than previously thought.
Howtown channel focuses on not just knowledge but on the processes used to uncover and understand scientific discoveries.
Ground News, developed by a former NASA engineer, helps users navigate news stories by providing comparative analyses of coverage.
Ground News aggregates news from around 50,000 sources, highlighting different perspectives and biases in media reporting.
The platform provides a visual breakdown of news stories, including coverage spectrum and ownership, to enhance understanding.
The 'Blind Spot' feature in Ground News helps users identify areas of underreported news, broadening their media consumption.
Insights into how different media outlets spin stories illustrate the importance of understanding bias in reporting.
The discussion on Neanderthals caring for a disabled child showcases the complexity of social behaviors in ancient human relatives.
Highlighting compassion and altruism in Neanderthals suggests that these traits may have ancient origins.
The overall narrative emphasizes the significance of staying informed and aware of different media biases for comprehensive understanding.
Transcripts
There's a secret in my family history,
and I'm not talking about my childhood
teddy bear addiction.
The truth was revealed a few years ago
thanks to genetic testing.
I have Neanderthal ancestors.
So it looks like
I have less than 2% Neanderthal DNA.
Interesting. Okay, I want to look at mine.
Okay.
It says less than 2% of my DNA.
But it's more than 31% of other customers.
There's growing scientific consensus that Joss
and I and every human on earth
has a little bit of DNA
passed down from ancient liaisons with a creature
who was once considered
a completely separate species.
The amount of Neanderthal DNA
you have depends on where your roots are.
But as we ask in every Howtown episode,
how do they know?
How did they figure that out?
It's a remarkable story.
Scientists had to reach back in time
and read the genetic code of people who died
50,000 years ago,
and then decrypt secret messages
hidden inside our living cells.
And their discoveries have rewritten
the established history of our species.
In 1856, in the Neander Valley of Germany.
Some miners unearthed this partial skull
along with a few other bones.
Scholars took a look at the remains and announced
that this was a new type of human.
Other bits
and pieces turned up from Spain to Siberia
in caves, in pits, sometimes fused into walls.
One of the skeletons
inspired this artist reconstruction,
which was widely published in 1909.
It helped popularize
a very specific image of Neanderthals
that survives to this day.
That early illustration was labeled
one of our first ancestors.
It was easy for readers
to imagine that this Neanderthal,
who could not assume
the upright position of the superior races,
was the uncivilized progenitor of the clever
skater on the same page.
But almost all of this turned out to be wrong.
For one thing,
the illustration’s reference skeleton
belonged to an old Neanderthal
with terrible arthritis.
Most of them actually stood up straight.
Plus, Neanderthals
weren't even around 20,000 years ago.
They went extinct several
thousand years before that.
And scientists
started debating
whether Neanderthals
were our evolutionary grandparents
or more like our distant great uncles.
The second theory was supported by the location
and timing of the remains.
Neanderthal bones
were found across this area
and dated to this time period.
Meanwhile, bones that looked like modern humans,
Homo sapiens, were found in Africa.
The oldest was around 200,000 years old.
This doesn't look like Neanderthals
gave rise to Sapiens.
This looks like two distinct populations
evolving separately on their own continents.
At some point, a group of sapiens left Africa,
and around the same time
they were spreading across the globe.
The intervals disappeared where Homo
sapiens and Neanderthals
were found in the same site.
The Neanderthals were always buried deeper,
separated by soil and time.
It looked like Team
Great Uncle was winning the debate.
But to really prove this,
they had to get their hands
on some Neanderthal DNA.
If you wanted to send a message
50,000 years into the future,
you wouldn't write that message in DNA.
There's so many things that can rip it to shreds.
Heat and light and moisture
and bacteria and even our own enzymes.
Ancient DNA is really low quality
and very difficult to work with.
And so you can't just take your run of the mill
molecular biology techniques
that you would use with modern DNA
and apply them to ancient samples.
But geneticists have slowly developed
new techniques.
In the 1980s, they coaxed a little DNA
out of a taxidermied quagga
that had died 140 years earlier.
They sequenced just 229 base pairs,
the letters of the genetic code.
Two years later, an enthusiastic Swede named
Svante Pääbo
published a paper on the DNA
he had collected from the face of a 2500 year
old mummy.
Meanwhile, DNA sequencing was swiftly improving.
Researchers who claim to have extracted DNA
from ancient insects
trapped in amber.
Suddenly, anything seemed possible.
Welcome
to Jurassic P--
But those amber results couldn't be replicated.
They are most likely just sequenced
some modern DNA
that had made its way into their samples.
And this contamination is a huge problem
for anyone trying to work with ancient DNA.
So if I touch the bone
and I sweat, I can transfer some DNA from my hand
to the bone
and the amount of DNA
that that will transfer
and can be like a million times more
than the DNA that is preserved inside.
Even Pääbo’s mummy DNA was questioned,
so he set out to eliminate sources
of contamination
using careful protocols that are now standard.
I have a whole clean suit that covers my entire
self a mask, hairnet, double gloves,
the whole nine yards.
Most of the people,
when they see us walking in that room, it's like,
oh my God, something dangerous is happening.
But we are actually protecting the sample.
I take actually a dentistry drill,
and I first clean off the surface
to remove potentially any of that contamination.
And after removing that first layer,
I then start to collect
small amounts of bone powder.
By the 2000, a more experienced
and cautious
Pablo embarked on an ambitious new project
sequencing the entire Neanderthal genome all
3.2 billion base pairs.
His team collected DNA from these
three shards of Neanderthal bone
that had been tucked in a cool,
dark Croatian cave for millennia.
Now, bone doesn't contain much DNA, even in life,
but DNA from the decomposing body
can seep into the bone
matrix and get stuck there.
And so Pääbo’s team was able to extract
and sequence a bunch of ancient DNA,
but it wasn't in great shape.
Those molecules that I'm getting out of
my bones are highly degraded, fragmented.
The chromosome will be like
hundreds of millions of bases
of units of DNA.
I got like a 30 to 50
bases. If a chromosome were enlarged
the length of the Boston Marathon,
These fragments
would be the size of a single baked bean.
And I try to find where they actually match,
like a puzzle.
It seems like really hard to know
if you're dealing
with such small fragments of DNA,
to know
that they are actually coming from the organism
that you want it to be coming
from, versus from a human,
or a bug or a microbe or something
that was just around. Exactly.
And in fact,
they think that most of the DNA
that they're getting is from microbes.
Assembling the entire Neanderthal genome
would be like solving a 20 million piece
puzzle with a bunch of other puzzles mixed in.
And there's no picture on the box.
They didn't have a full Neanderthal genome
to reference.
But they did have two recently completed genomes.
Sapiens and chimpanzees both come from a common
ancestor, splitting into two groups
millions of years ago.
The bundles of DNA in our cells, chromosomes,
look very similar.
And if you zoom in,
there's a different base, a different letter,
every 80 positions on average.
If you looked at the two of us,
it would be about every thousand base pairs
we'd have something different.
So there's still a fair amount of variation
just between individuals.
Since the Neanderthal-Sapiens split
is much more recent than our split with chimps,
you'd expect them to be pretty similar to us.
And you could use both genomes
as a reference, seeing
where little bits of Neanderthal DNA best line up.
This puzzle,
lining up method is how they can tell that
we're at least talking about a hominid and not a
microbe, right?
So the microbe pieces
aren't going to line up and overlap nicely.
It's a tedious process,
but of course, computers speed up the busywork.
In 2010, they published the first draft
of three full Neanderthal sequences.
As expected,
they were similar to ours,
with just one difference
every 600 positions on average.
Okay, so that shows that we're
we're related to them,
which I guess probably wasn't really disputed.
We knew we were related to them, just like
we know we're related to chimpanzees.
But to say that our ancestors
interbred with them seems like a different thing
that requires
more proof than just kind of showing
these similarities on the genome.
Totally.
We're back to that big question, grandpa versus
great uncle.
How did they figure out that our ancestors
knocked boots with Neanderthals?
The initial evidence came from something
called the Four-Population test.
We've got chimps and Neanderthals,
and then we can split Homo sapiens
into two groups:
The ones who stayed in Africa,
and those who left relatively recently
to live in Neanderthal territory.
I'll just switch to a logarithmic scale
so it's easier to see.
In most spots in the genome,
all four populations will have the same base
inherited from our common ancestor.
If you have a mutation here before the split,
you'd expect all three of these groups
to have that same change.
But if there was a mutation here,
you'd see that change only in Neanderthals.
When they compared the genomes, though,
there were a surprising number of places
where Neanderthals and Non-africans
shared the exact same change.
And there were often
several of these matches
in the same stretch of DNA.
Though it's possible that two identical mutations
could arise by chance
in Neanderthals and Sapiens,
you would expect
to see the same number
of coincidences in both sapiens groups,
not much more frequently in the group
that happened to visit Neanderthal territory.
Let me make sure I understand the logic of this.
Yeah.
So they find these similarities between us
and Neanderthals.
If our similarities with Neanderthals
could be attributed
to our common ancestry with Neanderthals,
then we would see those traits kind
of equally distributed across modern humans.
But instead,
they see a difference
in the amount of relatedness based on
whether the people's ancestors stayed in Africa
versus left into the part of the world
where Neanderthals were.
And thus the most obvious explanation
is that they were interbreeding.
Yeah, it is very suspicious, to say the least.
The scientists who made this
discovery were, in their own words,
strongly biased against the possibility
of Neanderthal interbreeding.
So they were deeply suspicious of their own data.
But the more they tested their conclusions,
the more data they gathered, the stronger
the evidence became that
people of Eurasian descent have Neanderthal DNA.
I remember learning somewhere
that different species
usually can't produce offspring that are fertile.
Yeah.
Is there an explanation for why that wouldn't
be the case here?
Well, the explanation is sort of
that “species” is a made up idea.
It's a squishy category and especially
within this research,
they don't really like to talk about species.
We are not using the term species anymore.
Even population gets difficult
now. We are using like lineage,
different human lineage or different human group.
We don't know how to define a species.
We don't know
how many
difference in the genomes
would make you a different species.
We don't even want to try to do it.
There's a lot of evidence that,
there might have been
some fertility issues
when these groups interbred.
But obviously it wasn't enough
to stop the mixing entirely.
They must have tried really hard.
They tried
really hard or enough times that it worked out.
But yeah, I mean,
all of these researchers
call Neanderthals “humans.”
The term “human” is a broader
term than just Homo Sapiens.
A few years ago,
a new paper offered evidence that all modern
human populations have Neanderthal DNA,
including Africans.
Instead of relying on a comparison of DNA
from different populations,
this study looked at the length of stretches
of DNA that matched Neanderthals.
Why would length be significant?
While chromosomes tend to get mixed up over time,
the child of a Neanderthal and a Sapien
would have one set of chromosomes
from each parent.
But in that child,
those chromosomes get slightly scrambled.
And with each generation that passes,
like the pulses of a food processor,
the continuous blocks of Neanderthal DNA
get smaller and smaller.
So longer length means more recent
influence.
So you can look through modern genomes
for stretches of Neanderthal flavored DNA
that aren't too short, which suggests
that they entered
the genome more recently through interbreeding.
Scientists
use this logic
in a more recently sequenced genome
that was higher quality to find shared DNA
between Africans and Neanderthals.
Part of the explanation
is that some sapiens must have picked up
some Neanderthal DNA in Eurasia,
and then migrated back into Africa.
That all leaves us with a new mystery.
Genetics strongly
suggests that interbreeding happened.
But we don't have any evidence from archeology
that Neanderthals and Sapiens ever
interacted until now.
A recent discovery, for the very first time,
gave us a glimpse of a specific moment
when and where these two groups crossed paths.
It all hinges on three clues: a single baby tooth,
a pile of stone blades,
and the smoke of ancient campfires
trapped in stone.
And like many mystery stories,
this one starts
with an enigmatic European detective.
The skull is an empty box.
It won't tell you anything of what
is in the brain of this population
and who they were.
If you want to understand the Neanderthal,
well you have to read the Naked Neanderthal.
Or you have to do, like me,
to spend 50 years in caves
trying to understand this incredible creature.
Since the 1990s, Ludovic has been excavating
a rock shelter in the Rhone valley of France.
When you're working in the cave,
you are entering it and living in a time capsule.
Several time capsules
release several distinct layers of Earth.
The top layer is relatively recent and contains
remnants of Stone age sapiens.
Further down, Ludovic found a set of teeth.
It's the most complete series of teeth
we ever found on Neanderthals.
So far, we're following that familiar pattern
a Sapien layer above, Neanderthals below.
In most of the layers,
they found Neanderthal teeth.
But in this layer, layer E, was a single
baby tooth that looked Homo sapien.
And it just looks like a human tooth.
Or do they have any molecular way
to confirm that it's a human tooth? Right.
So unfortunately, this exposed,
you know, rock shelter
wasn't the best place to preserve DNA.
So they had
previously tried to get DNA out of animal bones
that were in the same layer,
and they weren't able to get the DNA out of it.
It was too degraded.
And so they were like,
it's not worth it to destroy this tooth,
just to see if we can get DNA
when we probably won't be able to.
But they also know the exact measurements
and proportions
of features of Neanderthal and Sapien teeth.
The baby tooth
definitely fell into the Sapien category,
but it was in rough shape.
When this baby tooth discovery was made
some people were a little suspicious.
They're like, what can we say for sure?
It looks like a human tooth,
but is there so much damage
that maybe it's hard to tell.
But Ludovic didn't
just find teeth in these layers.
We have millions of objects.
The bones they left from the animals
they were hunting, the flint
they were making their tools with that.
If you study these tools, and Ludovic
has literally
looked at millions of them in his career,
you start to notice a key difference
between Homo sapiens and Neanderthals.
Some of these Neanderthal craft
can be really impressive
in terms of technologies,
but each of them is unique.
You have an incredible creativity,
and on the other side,
among Homo sapiens population,
you have an incredible efficiency,
an incredible standardization.
It's very boring.
We don't like any kind of transgression.
We must be all together doing the same thing.
In layers D and F.
Ludovic found lots of varied Neanderthal tools
in layer E, the baby tooth layer,
there was something different.
Careful measurements
revealed those boring standardized points.
They looked just like the tools found in Sapiens
settlements all the way over in Lebanon.
Together with the tooth
that's compelling evidence that the people from
layer E were Homo sapiens.
Okay. But even if it's there
and it's sandwiched
between two Neanderthal layers,
that could just mean that, you know, different
people visit
this place at different times in history, right?
And they could be separated
by hundreds, if not thousands of years.
The tools they use to date,
these things aren't very precise.
If you find, like a skeleton in your backyard
and you want to know how old it is, radiocarbon
dating would be great at telling you
if it's 20,000 years old or 20 years old.
But when you get specific, if you found
a Neanderthal skeleton and a human skeleton
that had lived a thousand years
apart from each other,
they might still look like
they had the same age using this technique.
It's like if yesterday
you were eating with Caesar
on your left and Charlemagne on your right.
And so this is what I mean “contemporary.”
It's contemporary at the scale of 2000 years.
It's good
for getting a general picture of things.
But when you want to say,
hey, did these two people meet?
It's pretty much impossible to use that tool.
So researchers turned to this new method,
one that I think is so ingenious.
Right next to the stone tools and bones,
they found lots of little rocks
that had chipped off the ceiling,
and they had bits of soot from ancient
campfires trapped inside.
When you cut them and when you polish them,
it can sometimes smell of burnt wood.
And sometimes it smells like
like a barbecue, like meat.
Whoa, whoa.
Ooh. Just that smell is preserved.
Yeah. in this rock.
And then you cut it open and you could smell it.
Exactly.
So the smell can be preserved.
The soot had drifted up to the ceiling
and then was sealed in place as calcium
crystals formed new rock over it.
During the rainy season,
more water
seeps through the rock, carrying more dissolved
calcium, and bigger crystals form.
In the dry season, smaller crystals.
So you can actually see this annual cycle
and count the years in these layers of rock.
A little bit like tree rings.
And when you look at it under the microscope,
you're just like,
oh my God, there's 20 different layers.
And each one of these soot traces
represents an occupation event.
And so you have a kind of a barcode.
Collecting all the ceiling fragments
in one layer gives you a bunch of these barcodes.
It's pieces of a puzzle.
And we have to build the puzzle.
And just like the DNA puzzle, computers can help
line up all these barcodes
to create a continuous history.
Here's that history for layer F, a Neanderthal
layer, and here's
the one for the baby tooth layer, Layer E.
Incredibly, they overlap.
Between the last Neanderthal fire
and the first Sapiens fire,
the rock recorded just one seasonal cycle.
That was really surprising.
It wasn't just less than a human generation,
it was estimated to a year.
There on that specific territory,
we have the two populations, not more or less
a thousand years,
Not with Charlemagne
and Julius Caesar,
but in terms of the true life of a person.
These two groups
must have known about each other.
Maybe they even watched each other
from this rock shelter.
Wow.
What must of that have been like?
It's just a hint of an encounter,
one without any suggestion of interbreeding,
and one that we'll need more evidence
to convince the skeptics.
But our genomes tell us that moments like this
must have happened many times.
There's a new sort of picture forming.
Instead of this pure line of Homo
sapiens marching out of Africa,
we now have a much more chaotic family
story, with multiple waves of humans
leaving the continent,
sometimes to die off, sometimes to return,
sometimes to flourish,
and sometimes to mix with strangers.
And not just with Neanderthals.
Scientists found the remains of another type
of ancient human in a Siberian cave,
and genetics showed
that these Denisovans also mixed with sapiens.
And there's growing evidence that our genomes
contain traces of even more unknown archaic
humans, ones
whose remains we haven't even found yet.
And the Neanderthals?
They are our great uncles
from a different branch.
But they're also among our great,
great, 2000-times-great grandparents.
This picture of the human family
tree is much messier,
and I think much more believable.
Howtown is a channel that's not
just about what we know,
but the different ways we figure stuff out.
And if you like that,
you can support us by signing up for our Patreon.
There's a lot of nuance and uncertainty
when it comes to research methods,
and there's a whole other level of complexity
that gets added
when those discoveries are reported in the news.
That's where the sponsor for this video comes in.
Ground news. Ground news.
What is that?
So Ground
News is a website and app developed by a former
NASA engineer named Harleen Kaur.
It gathers
news stories from like 50,000 different sources,
so you can compare how different outlets
cover the news.
So I feel like as a news consumer, it's very hard
to navigate all of the different stories.
How would something like this
make that easier for me?
It gives you some more metadata basically.
For every story you've got
this visual breakdown of who covered the story,
where they land
on this spectrum of political bias.
You can see how factual those outlets tend to be.
And who owns them.
And all that info is coming from these three
independent news-monitoring organizations.
I see.
But let me just show you what it looks like.
Neanderthals in Spain care for a disabled child
with Down Syndrome, study finds.
I never saw that headline.
This is, I guess two months ago
this news came out.
This allows you
to see how the different outlets
sort of put their spin on the news.
So a lot of the--
The abortion angle.
So the National Review has an abortion angle.
The left-of-center news
outlets are talking a lot
about how compassion and altruism
are this ancient thing. I think
the thing that I like the most about Ground News
is they have this Blind Spot feature.
You know,
it's very easy
for us to be in our little media bubbles.
On the top, it says “for the left.”
So that means for the people on the left,
this is where you would go to see
what your blind spots are?
Exactly. News stories that had little
to no reporting on the left.
I think this is a good tool
for understanding the news,
which is of course one of our goals.
So if you want access to this tool,
you go to ground.news/howtown
to get 40% off their Vantage plan,
which is the one that I have access to.
If you support them, it's a way of supporting us.
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