Introduction to Anatomy & Physiology - Chapter 2: Cells and Tissues
Summary
TLDRThis video from the Anatomy and Physiology course delves into the intricacies of cells and tissues. It explains the cell's structure, including the cell membrane, nucleus, and organelles like mitochondria and the Golgi apparatus. The video also covers cell functions, communication, and division, highlighting the significance of the Human Genome Project. Tissues are explored, detailing their types and functions, such as epithelial for protection and muscle for contraction. The video concludes with a discussion on membranes, emphasizing their role in lining and covering body surfaces.
Takeaways
- π The organization of the body follows a hierarchy: from atoms to cells, to tissues, to organs, to systems, and finally to the organism.
- π¬ The cell is highly complex with components such as a control center (nucleus), internal transport, and power plants (mitochondria).
- 𧬠Cells are mainly composed of water, proteins, sugars, fats, and minerals, making them the fundamental unit of all living things.
- π Light microscopes use visible light, while electron microscopes offer detailed views of the cell's ultrastructure.
- π§ͺ The cell membrane regulates what enters and leaves the cell, consisting of a bilayer of lipids with embedded proteins.
- 𧫠The nucleus acts as the control center, containing chromosomes with genes made up of DNA, which regulates cell functions.
- 𧬠Humans have 23 pairs of chromosomes, and the Human Genome Project mapped 30,000 genes to help in treating disorders like cancer and diabetes.
- π₯ Mitochondria generate energy for the cell through ATP, play roles in cell death (apoptosis), and can influence health and aging.
- π Diffusion, osmosis, and filtration are key passive processes for moving materials in and out of cells without requiring energy.
- πͺ Muscle tissues consist of skeletal, cardiac, and smooth muscles, with skeletal muscles being voluntary and the others involuntary.
Q & A
What are the different levels of organization in the human body from the most basic to the most complex?
-The organization levels of the human body from the most basic to the most complex are: cells, tissues, organs, systems, and finally the organism.
What are the two types of microscopes mentioned in the script, and what are their primary functions?
-The two types of microscopes mentioned are the light microscope and the electron microscope. The light microscope uses visible light for illumination, while the electron microscope allows researchers to study the fine detail and ultrastructure of cells and their parts.
What is the primary function of the cell membrane, and what is its composition?
-The primary function of the cell membrane is to protect the cell and regulate what passes into and out of the cell. It is composed of a double layer of lipids, specifically phospholipids, with various proteins embedded within.
What is the nucleus of a cell, and what are its key features?
-The nucleus is the control center of the cell, typically a large rounded organelle surrounded by a double membrane called the nuclear envelope. It contains chromosomes, which are regions called genes that contain DNA.
What is the significance of the Human Genome Project, and when was it completed?
-The Human Genome Project was significant because it mapped the approximately 30,000 genes that make up the human genome. The project was completed in 2003 and has been applied to developing technology for the prevention and treatment of many disorders, including cancer and diabetes.
What is a karyotype, and how is it used in determining chromosomal abnormalities?
-A karyotype is a photograph of an individual's chromosomes arranged by size, shape, and number. It is used to determine whether chromosomes are normal or abnormal, such as in the case of Down syndrome (trisomy 21) where there are three chromosomes at number 21.
What are the functions of the endoplasmic reticulum and the Golgi apparatus in a cell?
-The endoplasmic reticulum (ER) is a network of canals within the cell that manufacture proteins. There are two types of ER: rough ER, which has ribosomes along its outwalls, and smooth ER, which synthesizes steroids, phospholipids, and fatty acids. The Golgi apparatus functions as a protein processing and packaging plant and also produces lysosomes.
What is the role of mitochondria in a cell, and how do they relate to health and aging?
-Mitochondria are the power plants of the cell, carrying on cellular respiration to break down fuel molecules and release their energy. They can affect health and aging by leaking electrons that form free radicals, which are highly toxic and reactive compounds that interfere with normal cell functions. Mitochondria also play a role in programmed cell death, known as apoptosis.
How do cells communicate with one another, and what are the steps involved in cell signaling?
-Cells communicate by signaling one another through a sequence of events: 1) a cell sends a signal, usually a chemical compound like a hormone, 2) reception, where specific proteins on target cells bind with the signal, 3) signal transduction, where a receptor converts an external signal into an internal one, and 4) response, where some cell activity is altered.
What are the four stages of mitosis, and what happens during each stage?
-The four stages of mitosis are prophase, metaphase, anaphase, and telophase. During prophase, chromatin coils making chromosomes visible, and the nuclear membrane dissolves. In metaphase, chromosomes position along the equator of the cell. Anaphase sees sister chromatids separate, and chromosomes move toward opposite ends. Finally, in telophase, chromosomes begin to uncoil, and the nuclear membrane forms around each set.
What are the different types of tissues in the body, and what are their primary functions?
-The different types of tissues include epithelial tissue (protection and secretion), connective tissue (joining, supporting, and protecting), muscle tissue (contraction), and nervous tissue (transmitting information). Epithelial tissue forms glands and lines body cavities, connective tissue includes cartilage, bone, and blood, muscle tissue is responsible for movement, and nervous tissue is composed of neurons and glial cells.
Outlines
π¬ Introduction to Cells and Tissues
This paragraph introduces the study of cells and tissues in anatomy and physiology, highlighting the complexity of cells despite their microscopic size. It explains the hierarchical organization of the body, from cells to tissues to organs and systems. The paragraph details the components of a cell, including the cell membrane, nucleus, chromosomes, and various organelles such as mitochondria, endoplasmic reticulum, and Golgi apparatus. It also touches on the use of light and electron microscopes to observe cells and their structures. The nucleus is described as the control center of the cell, with chromosomes and genes playing a crucial role in cell activities and the human genome. The Human Genome Project is mentioned, emphasizing its contribution to understanding genetic disorders.
𧬠Cell Structure and Function
This section delves deeper into the structure and function of various cell components. It discusses the cell membrane's role in protecting and regulating the cell's contents, the nucleus as the control center, and the nucleolus's role in ribosome assembly. The endoplasmic reticulum, with its rough and smooth forms, is explained in terms of protein synthesis and lipid production. The Golgi apparatus is described as a protein processing and packaging plant. Lysosomes are introduced as digestive enzymes containing sacs, and mitochondria are explained as the cell's power plants, responsible for cellular respiration and ATP production. The paragraph also covers the cytoskeleton, microtubules, cilia, and flagella, and how substances move through the plasma membrane via passive processes like diffusion, osmosis, and filtration. Active transport mechanisms, such as the sodium-potassium pump, are also explained.
π Cell Communication and Division
This paragraph focuses on how cells communicate with each other and the process of cell division. It outlines the steps of cell signaling, including signal sending, reception, transduction, and response. The importance of cell communication in tissue formation, homeostasis, and defense against diseases is emphasized. The process of cell division, specifically mitosis, is detailed through its stages: prophase, metaphase, anaphase, and telophase. The life cycle of a cell, including interphase and the mitotic phases, is also discussed, highlighting the importance of mitosis in ensuring the proper distribution of chromosomes to new cells.
πͺ Tissues and Membranes
The final paragraph shifts focus to tissues, which are groups of cells that work together for specific functions. It describes the different types of tissues: epithelial, connective, muscle, and nervous. Epithelial tissues are discussed in terms of their protective and secretory functions, with examples of various types of epithelial cells and glands. Connective tissue's role in joining, supporting, and protecting the body is explained, with details on different types of fibers and tissues like cartilage and bone. Muscle tissue is explored, differentiating between skeletal, cardiac, and smooth muscles, and their functions. Nervous tissue's role in transmitting information via neurons and glial cells is also covered. The paragraph concludes with a discussion of membranes, including epithelial, mucous, serous, and connective tissue membranes, and their functions in lining and covering body surfaces.
Mindmap
Keywords
π‘Cell
π‘Cell Membrane
π‘Nucleus
π‘Chromosomes
π‘DNA (Deoxyribonucleic Acid)
π‘Mitochondria
π‘Endoplasmic Reticulum
π‘Golgi Apparatus
π‘Tissues
π‘Cell Signaling
Highlights
Cells are the fundamental units of all living things, with complex structures including a control center, internal transportation system, power plants, and factories for making needed materials.
Light and electron microscopes are essential tools for observing cells, with light microscopes using visible light and electron microscopes revealing fine details and ultrastructure.
The cell membrane is a thin plasma membrane that protects the cell and regulates the passage of substances in and out.
The nucleus serves as the control center of the cell, surrounded by a double membrane and containing chromosomes and genes that regulate cell activities.
Chromosomes are composed of DNA and proteins, with genes on chromosomes acting as recipes for making specific proteins.
The Human Genome Project, completed in 2003, mapped the human genetic material, which has applications in preventing and treating disorders like cancer and diabetes.
Karyotyping involves arranging an individual's chromosomes by size, shape, and number to determine if they are normal or abnormal, such as in Down syndrome.
The nucleolus is a region within the nucleus that assembles ribosomes, which are essential for protein synthesis.
The endoplasmic reticulum is a network of canals within the cell that manufactures proteins, with two types: rough and smooth, each serving different functions.
The Golgi apparatus functions as a protein processing and packaging plant, also producing lysosomes that contain digestive enzymes.
Mitochondria are the cell's power plants, carrying out cellular respiration and releasing energy stored in ATP for various cellular processes.
Vesicles are small membrane-enclosed structures that transport cargo within the cell, and vacuoles are larger sacs involved in ingesting large particles.
The cytoskeleton provides structural support within the cell and is involved in cell movement and division.
Cilia and flagella are hair-like organelles that aid in cell movement, with flagella propelling sperm cells towards the ovum.
The plasma membrane is selectively permeable, allowing certain substances to pass while preventing others, with materials moving through it via diffusion, osmosis, and filtration.
Active transport moves materials against a concentration gradient, requiring energy expenditure and examples include sodium-potassium pumps.
Phagocytosis and pinocytosis are forms of active transport where cells ingest large particles and droplets of fluid, respectively.
Cell communication is essential for processes like tissue formation and homeostasis, involving signaling between cells through chemical compounds like hormones.
Cell division, including mitosis with its stages of prophase, metaphase, anaphase, and telophase, ensures the chromosomes are duplicated and distributed to new cells.
Tissues are groups of cells that work together for specific functions, with major types including epithelial, connective, muscle, and nervous tissues.
Epithelial tissues provide protection and secretion, with variations like simple, stratified, and pseudostratified epithelium, and glandular formations.
Connective tissues support and protect, with types including loose connective tissue, adipose tissue, cartilage, and bone, containing fibers like collagen and reticular fibers.
Muscle tissues contract, with skeletal, cardiac, and smooth muscle types, each with specific structures and functions.
Nervous tissue transmits information, composed of neurons and glial cells, with sensory neurons detecting changes and motor neurons transmitting information to muscles and glands.
Membranes cover or line body surfaces, with epithelial membranes like mucous and serous membranes serving different functions in the body.
Transcripts
welcome to anatomy and physiology
chapter 2.
the information is credited to this book
Wikipedia and many other sources
chapter 2 covers cells and tissues
a quick reminder that the organization
level of the body is from Adam to cells
to tissues to organs then to systems and
finally organism
cell the cell is amazingly complex it
has a control center internal
transportation system power plants a
factory making needed materials and
packaging plants despite their
complexity most cells are so small that
they can be observed only under a
microscope
light microscope uses visible light as
the source of Illumination
and
the electron microscope enables
researchers to study the fine detail
Ultra structure of cells in their parts
the photograph taken with a light
microscope is referred to as a light
micrograph LM whereas one taken with an
electron microscope is an electron
micrograph em
cell all cells are similar in that they
contain a gelatinous substance composed
of water protein sugar fats and various
minerals the cell is a fundamental unit
of all living things major parts of the
cell include cell membrane nucleus
chromosomes Gene DNA karyotype cytoplasm
mitochondria endoplasmic reticulum and
Golgi apparatus
let's first discuss the cell membrane
cell membrane surrounds by a thin plasma
membrane that protects and regulates
what passes into the out of the cell the
plasma membrane consists of a double
layer by layer of lipids phospholipids
in which a variety of proteins are
embedded
nucleus is the control center of the
cell it's typically a large rounded
organelle surrounded by a double
membrane called the nuclear envelope
nucleus pores in the nucleus envelope
allow the passage of material between
the nucleus and cytoplasm
chromosomes the nucleus contain Loosely
coiled material called chromatin when a
cell prepares to divide the chromatin
coils tightly and condense to form
rod-like structures within the nucleus
all human body cells except for the sex
cells the egg and the sperm short for
spermatozo on contains 23 pairs of
chromosomes
each sperm in each egg cell have only 23
of her chromosomes after an egg in a
sperm cell United to form the embryo
each cell of the embryo then has 46
chromosomes 23 pairs
Gene chromosomes regions called genes
thousands each gene contains a chemical
called DNA
deoxyribonucleic acid
DNA regulates the activities of the cell
according to its sequence's Arrangement
into genes on each chromosome DNA
sequence resembles a series of recipes
in code this code then passed out to the
nucleus to the rest of the cell directs
the activities of the cell such as cell
division and synthesis of proteins
we can think of the chromosomes as a
chemical cookbook for the cell the genes
are recipes for making specific proteins
the complete set of genes that make up
the human genetic Mater is the human
genome
the Human Genome Project completed in
2003 mapped their 30 000 or so genes
that made up the human genome here is a
connection why this matters the
knowledge and experience scientists
gained from their work on the Human
Genome Project research has been applied
to developing technology for prevention
and treatment of many disorders
including cancer and diabetes
karyotype is a photograph of an
individual's chromosomes arranged by
size shape and number
karyotyping can determine whether
chromosomes are normal
this is an abnormal karyotype of down
syndrome trisomy 21 it has three
chromosomes at number 21.
the nucleolus is a granular region
within the nucleus the nucleus assembles
ribosomes organelles that help
manufacture proteins
the endoplasmic reticulum is a network
reticulum of canals within the cell
these canals are cellular tunnel systems
that manufacture proteins for the cell
there are two types of er R rough and
smooth the rough ER has a granular
appearance that results from organelles
called ribosomes along its outwalls
ribosome function as factories where
proteins are manufactured
smooth ER is specialized to synthesize
steroids phospholipids and fatty acids
in the liver cells smooth ER has enzymes
that break down many drugs including
alcohol and amphetamines
Golgi complex is composed of layers of
plate-like membranes this organelle
functions as a protein processing and
packaging plant it also produces
lysosomes
lysosomes are little sacs that contain
about 40 different digestive enzymes
that destroy bacterial and other foreign
matter under some conditions lysosomes
break down organelles the components of
these organelles can then be recycled or
used as an energy source
mitochondria are the power plant these
organelles carry on cellular respiration
the process of breaking down fuel
molecules and releasing their energy
some of the energy is temporarily stored
in ATP adenosine triphosphate a chemical
compound that can be used to power a
variety of chemical reactions in the
cell
mitochondria can affect health and aging
by leaking electrons that form free
radicals and highly toxic and reactive
compounds interfere with normal cell
functions
mitochondria also play an important role
in program cell death referred to as
apoptosis a normal part of development
and maintenance
vesicles is a small membrane enclosed
structure that holds or transports some
type of cargo within the cell vesicles
are covered by a vacuole a larger
membrane enclosed Sac found in the
cytoplasm
evacule a larger membrane enclosed Sac
found in the cytoplasm vacuoles form
when a cell ingested a large particle
such as a bacterium
cytoskeleton is a dense network of tiny
protein filaments provide structural
support and is important in transporting
materials within the cell the
cytoskeleton helps determine the shape
of a cell and its ability to move it is
also important in cell division
microtubules one of the components of
the cytoskeleton are tiny hollow tubes
that provide support
microtubules are components of cilia and
flagella organelles important in
movement
cilia are tiny hair-like organelles that
project from the surface of some types
of cells used to to move materials
outside the cell
sperm cell is equipped with a flagellum
a whip-like tail that propels it toward
the ovum egg
materials move through the plasma
membrane plasma membrane is selective
permeable this means that it allows
certain substances to enter or leave the
cell while preventing the passage of
other substance
materials move through the cell
membranes passively by physical
processes including diffusions osmosis
and filtration these processes do not
require the cell to expend metabolic
energy
diffusion is the net movement of
molecules or ions from a region of
higher concentration to a region of
lower concentration bought about by the
energy of the molecules diffusion
depends on the random movement of
individual molecules
in the above illustration when a cube of
sugar is dropped in the water its
molecules dissolve then the modules
begin to diffuse through the water and
eventually the sugar molecules are
evenly distributed throughout the water
gases and nutrients move in and out of
cells by diffusion
osmosis is the diffusion of water
molecules through a selectively
permeable membrane from a region where
water molecules are more concentrated to
a region where they are less
concentrated
the dissolved ions and molecules solute
in the more concentrated solution pull
the water molecules across the membrane
by the force called the osmotic pressure
when living cells are placed in a
solution that has a solute concentration
that is isotonic equal to that of the
cells the water molecule concentration
is also equal and therefore water
molecules move in out of the cells at
the same rate
when cells are placed in a solution with
a solute consultation that is hypertonic
greater compared with that of the cell
water leaves the cells causing them to
dehydrate shrink and perhaps die
when cells are placed in a hypotonic
solution ion of lesser concentration
compared with that of the cell the cell
exerts an osmotic pressure on the
solution water moves into the cells
causing them to swell and perhaps burst
filtration is the passage of materials
through membranes by mechanical pressure
for example blood pressure forces some
of the liquid parts of the blood plasma
through the capillary wall by filtration
this is how tissue fluid is produced
the cell must actively move some
materials from a region of lower
concentration to a region of higher
concentration that is against a
concentration gradient working a pill
against a concentration gradient
requires the cell to expend energy in
active transport the cell must use some
of its stored energy ATP to drive the
active transport
an example of active transport is the
sodium potassium pumps found in the
plasma membrane of virtually all cells
each pump consists of a group of
specific proteins in the plasma membrane
ATP provides energy to pump sodium ions
out of the cell at the same time
potassium ions are moved into the cell
phagocytosis means cell eating it is a
form of active transport in phagocytosis
cells in just large solid particles such
as cellular debris of bacteria
pinocytosis sometimes called cell
drinking is another example of active
transport folds of the plasma membrane
track drops of fluid containing
dissolved particles the folds are
pinched off into the cytoplasm as small
vesicles the vesicles become smaller as
their contents are slowly transferred
into the cytoplasm
cells of the body must communicate with
one another to carry out essential
processes for example cells must
recognize one another to form tissues
cells also signal information about the
condition of the body and then sends
signals to initiate or terminate
processes that restore homeostasis many
types of cells must communicate to
protect the body against invading
disease organisms cells communicate by
signaling one another
a sequence of events takes place in cell
signaling step one a cell must send a
signal usually a chemical compound such
as a hormone
Step 2 reception receptors specific
proteins on target cells cells that can
respond to a specific signal bind with
the signal
step 3 signal transduction a process by
which a receptor converts a signal
outside the cell into a signal inside
the cell that affects some cellular
process
and step 4 response by the cell some
cell activity is altered
cell division certain cell types in the
body are divided almost continuously for
example stem cells in the red bone
narrow produce more than 2 million red
blood cells every second however the
mature blood cells do not divide before
a cell divides to form two cells the
chromosomes are precisely duplicated and
the cell undergoes mitosis mitosis has
four stages prophase metaphase anaphase
and telophase
life cycle stages of a cell include
interphase the period of growth and
activity between mitosis a cell
reproduces Itself by undergoing mitosis
and then dividing to form two new cells
note that there are 46 chromosomes in
this phase
during prophase the first stage of
mitosis the chromatin coils making the
chromosomes visible the nuclear membrane
dissolves centrioles migrate toward
opposite ends of the cell and a spindle
made of microtubules forms
during metaphase the chromosomes
position along the Equator of the cell
think of metaphase like in the Middle
with the letter m
during anaphase sister chromatid
separate and the two sets of chromosomes
move toward opposite ends of the cell
during telophase chromosomes begin to
uncoil and the nuclear membrane forms
around each set of chromosomes cell
division occurs
mitosis ensures that the chromosomes are
duplicated and distributed to each new
cell
this is the summary of the stages of a
cell's life cycle please learn this
cycle well
let's move on to tissues a tissue is a
group of closely associated cells that
work together to carry out a specific
function or group of functions
the major function of epithelial tissue
is protection it covers the body and
lines the body cavities some epithelial
tissue is specialized for secretion and
forms glands based on shape epithelial
cells may be squamous cuboidal or
columnar epithelial cells may be
arranged to form simple stratified or
pseudostratified epithelial tissue
a gland consists of one or more
epithelial cells specialized to produce
and secrete a products such as mucus
sweat saliva milk enzymes or hormones
for example in image a goblet cells in
the lining of the intestine secrete
mucus a slippery protective substance
there are two types of glands exocrine
and endocrine exocrine glands have ducts
tubes that also consist of epithelial
cells through which the secretion is
discharged to some body surfaces these
are the exocrine glands
endocrine glands do not have ducts they
release their products called hormones
into the surrounding tissue fluid the
hormone molecules usually diffuse into
the blood which transports them to their
destination below are the endocrine
glands in the human body
connective tissue joins other body
tissues supports the body and protects
underlying organs some main types of
connective tissue are loose connective
tissue adipose tissue cartilage bone
blood lymph and tissues producing blood
cells
three types of connective tissue fibers
are collagen fibers reticular fibers and
elastic fibers
whereas epithelial cells fit closely
together the cells of connective tissue
are separated by intercellular substance
which consists of thread-like fibers
scattered through a thick gel called a
matrix
collagen fibers contain the protein
collagen the most abundant protein in
the body
fibroblasts blue cells in the picture
the fiber producing cells and
macrophages the large scavenger cells
are commonly found in connective tissues
loose connective tissue also called a
realer tissue joints body structures it
is found as a thin filling between body
parts and serves as a reservoir for
water and salts
adipose fat tissue stores fat and
releases it when the body needs energy
adipose tissue helps to shape and
protect the body and provides insulation
cartilage tissue found in some
supporting structures such as in the
discs that serve as cushions between the
vertebra and at the ends of some bones
cartilage cells called chondrocytes
secret a tough rubbery Matrix as well as
collagen fibers the cartilage cells are
found in small cavities culpicuni in The
Matrix
like cartilage bone consists mainly of
Matrix bone cells called osteocytes are
located in lecune within the Matrix a
typical bone has an outer layer of
compact bone that surrounds an inner
region of spongy bone compact bone is
made up of single-shaped units called
osteons
muscle tissue which consists of
elongated cells called muscle fibers is
specialized to contract there are
different types of muscle tissues
skeletal cardiac and smooth
skeletal muscle and cardiac muscle
fibers are striated or striped
skeletal muscle is attached to bones and
is voluntary
cardiac muscle has intercalated discs
tight junctions between adjacent muscle
fibers that allow rapid transmission of
information
smooth muscle and cardiac muscle are
involuntary
smooth muscle functions in the movement
of internal organs
once again both smooth muscle and
cardiac muscle are involuntary for
example at night when you sleep your
heart still Beats
nervous tissue is specialized to
transmit information it consists of
neurons and glial cells which support
the neurons a neuron has a large cell
body that contains the nucleus and from
which extend dendrites specialize for
receiving impulses and an axon that
transmits information away from the cell
body
Sensory neurons receive information from
sensory receptors structures that detect
information about changes in the
internal or external environment for
example touch receptors in the skin and
photoreceptors in the retina of the eye
these neurons transmit information to
the brain and spinal cord motor neurons
transmit information from the brain and
spinal cord to muscles and glands
membranes cover or line body surfaces
membranes are sheets of tissue that
cover or line body surfaces
epithelial membranes consist of
epithelial tissue and a layer of
underlying connective tissue
a mucous membrane or mucosa lines body
cavities that open to the outside of the
body
serous membrane or sarasa lines a body
cavity that does not open to the outside
of the body the portion of the membrane
attached to the wall of the cavity is
the parietal membrane whereas the part
of the membrane that covers the organs
inside the cavity is the visceral
membrane
the membranes that cover bone and
cartilage are examples of connective
tissue membranes
the synovial membrane is a connective
tissue membrane that lines the joint
cavities
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