Psikoneuroimunologi (Bagian 1)

Summary

This educational video introduces psychoneuroimmunology, the study of interactions between the nervous, endocrine, and immune systems. It outlines the historical development of the field, starting from the 1919 discovery that stress can affect tuberculosis development. The video explains how psychological factors can influence the immune system through the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system, impacting immune cell function and behavior. It also discusses cytokines, molecules secreted by immune cells that affect the central nervous system and physiological responses to illness, such as mood, fever, appetite, and sleep patterns.

Takeaways

• 📚 The video is a remote learning program on the topic of psychoneuroimmunology from the Nursing Department of Padjadjaran University.
• 👨‍🏫 The lecturer is Usman Ibrahim, a lecturer at the Faculty of Nursing, Padjadjaran University.
• 🔍 The material is divided into three parts, aiming to explain the definition and concepts of psychoneuroimmunology, its history, and its relationship with health.
• 🤔 Psychoneuroimmunology is a field that studies the interaction between the central nervous system, the endocrine system, and the immune system, and the impact of behavior or stress on the body's immune response.
• 📉 Since 1919, stress has been known to affect the development of diseases like tuberculosis.
• 🐭 In 1974, Robert Ader conducted the first experiment on mice, showing that immune responses can be modified through conditioning.
• 🧠 The central nervous system influences the immune system through the hypothalamic-pituitary-adrenal (HPA) axis, which controls the secretion of hormones affecting immune function.
• 💉 Immune cells have receptors for HPA molecules, and their number and function can change due to hormonal secretion through the autonomic nervous system.
• 🚀 Cytokines, secreted by immune cells, are part of the body's defense against foreign substances and also influence the central nervous system and the HPA axis.
• 🌡 Cytokines also promote physiological responses to illness, affecting mood, fever, appetite, sleep patterns, and related behaviors.
• 🧬 The psychological state can impact the immune system and susceptibility to diseases, as shown by changes in nerve impulse rates and neurotransmitter changes in the brain.

Q & A

What is the main topic of the video lecture?

The main topic of the video lecture is psycho-neuro-immunology, which studies the interaction between the central nervous system, the endocrine system, and the immune system.

Who is the lecturer in the video?

The lecturer in the video is Usman Ibrahim, a lecturer at the Faculty of Nursing, Padjadjaran University.

What is the purpose of learning about psycho-neuro-immunology in this video?

The purpose of learning about psycho-neuro-immunology is to understand the definition and concepts of psychology, its application, the history of its development, and the relationship between psycho-neuro and immunology.

How was the impact of stress on health first recognized in the context of psycho-neuro-immunology?

The impact of stress on health was first recognized in 1919 when it was found that stress could influence the development of tuberculosis.

Who conducted the first experiment on the relationship between behavior and the immune response?

Robert Ader conducted the first experiment in 1974 on mice, demonstrating that the immune response could be modified through conditioning.

What is the role of the hypothalamic-pituitary-adrenal (HPA) axis in psycho-neuro-immunology?

The HPA axis plays a central role in psycho-neuro-immunology as it controls the secretion of hormones that modulate the immune system, and immune cells are equipped with receptors to receive molecules from the HPA axis.

How does the autonomic nervous system affect the immune system?

The autonomic nervous system has a direct effect on the immune system through the secretion of neurotransmitters and other molecules that can influence the activity and distribution of immune cells.

What is the significance of cytokines in the interaction between the immune system and the central nervous system?

Cytokines are significant because they are molecules secreted by immune cells that can influence the central nervous system, affecting mood, fever patterns, appetite, and sleep, as well as other related behaviors.

How do psychological factors influence the immune system through the nervous system?

Psychological factors influence the immune system through the nervous system by affecting the secretion of hormones and neurotransmitters that can modulate immune responses and susceptibility to diseases.

What changes can psychological states induce in the brain related to the immune system?

Psychological states can induce changes in the brain related to the immune system, such as alterations in the firing rate of neurons and the release of neurotransmitters.

What is the significance of the historical development of psycho-neuro-immunology mentioned in the script?

The historical development of psycho-neuro-immunology is significant as it provides a foundation for understanding how the field has evolved, starting from the early recognition of stress's impact on health to the more recent understanding of the intricate interactions between the brain, behavior, and the immune system.